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11. 发明申请

WO2012093364A1 COMPUTED TOMOGRAPHY SYSTEM AND METHOD FOR TRACKING A BOLUS 审中-公开
标题翻译：计算机图像系统和追踪玻璃的方法
公开(公告)号：WO2012093364A1
公开(公告)日：2012-07-12
申请号：PCT/IB2012/050042
申请日：2012-01-04
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , SCHMITT, Holger , GRASS, Michael
发明人： SCHMITT, Holger , GRASS, Michael
IPC分类号： A61B6/03
CPC分类号： G06T11/008 , A61B6/032 , A61B6/469 , A61B6/481 , A61B6/488 , A61B6/504
摘要： The present invention relates to a computed tomography system (10) and a corresponding method which enable tracking of a contrast material bolus and which involve a reduced radiation dose. The proposed computed tomography system (10) comprises an acquisition unit including an X-ray source (18) and an X-ray detector (30) for acquiring projection data sets (42, 44, 46), a reconstruction unit (41) for reconstructing a planning image (48) from a first projection data set (42), an identification unit (52) for identifying a region of interest (40) in the planning image (48), a selection unit (54) for selecting a projection angle (60) through the region of interest (40), a calculator (62) for calculating a target projection value (64) for a projection of said region of interest (40) with the selected projection angle (60), a control unit (32) for controlling said acquisition unit to acquire a second, reduced projection data set (44) including projection data from projections of said region of interest (40) with the selected projection angle (60), and a comparator (68) for comparing projection values of the second projection data set (44) with the target projection value (64), wherein the control unit (32) is adapted to control the acquisition unit to initiate the acquisition of a third projection data set (46) based on the comparison result (70) and to reconstruct a diagnostic image (50) from the third projection data set (46).
摘要翻译：本发明涉及计算机断层摄影系统（10）和相应的方法，其能够跟踪造影剂推注并且涉及减小的辐射剂量。所提出的计算机断层摄影系统（10）包括：采集单元，包括用于获取投影数据组（42,44,46）的X射线源（18）和X射线检测器（30）;重建单元（41），用于从第一投影数据集（42）重建规划图像（48）;识别单元（52），用于识别所述规划图像（48）中的感兴趣区域（40）;选择单元（54），用于选择投影通过感兴趣区域（40）的角度（60）;计算器（62），用于计算用于所选择的投影角度（60）的所述感兴趣区域（40）的投影的目标投影值（64）;控制单元（32），用于控制所述获取单元以选择的投影角度（60）获取包括来自所述感兴趣区域（40）的投影的投影数据的第二缩减投影数据集（44），以及比较器第二投影数据集（44）的投影值与目标投影值（64），w 这里，控制单元（32）适于控制采集单元基于比较结果（70）开始获取第三投影数据集（46），并且从第三投影数据集重建诊断图像（50）（46）。

12. 发明申请

WO2012011036A1 3D-ORIGINATED CARDIAC ROADMAPPING 审中-公开
标题翻译： 3D原始的心脏道路交通
公开(公告)号：WO2012011036A1
公开(公告)日：2012-01-26
申请号：PCT/IB2011/053169
申请日：2011-07-15
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , FLORENT, Raoul , AUVRAY, Vincent , GRASS, Michael , SCHAEFER, Dirk , SCHOONENBERG, Gert Antonius Franciscus
发明人： FLORENT, Raoul , AUVRAY, Vincent , GRASS, Michael , SCHAEFER, Dirk , SCHOONENBERG, Gert Antonius Franciscus
IPC分类号： A61B6/12 , G06T7/00 , A61B19/00
CPC分类号： A61B6/022 , A61B6/12 , A61B6/4441 , A61B6/463 , A61B6/487 , A61B6/504 , A61B6/5223 , A61B6/5235 , A61B2090/364 , A61B2090/367
摘要： The present invention relates to 3D-originated cardiac roadmapping. In order to improve the accuracy of the information provided to the user as navigation information, without any additional burden to the patient such as additional X-ray dose, a method is described comprising the steps of a) providing 3D+t image data of a vascular structure of an object; b) acquiring two-dimensional image data of the object, which object comprises the vascular structure, the 2D image data comprising at least one 2D image; c) projecting the vascular structure, thereby generating a plurality of mask images on the basis of a 3D+t image data; d) registering the at least one 2D image with one of the plurality of the mask images, wherein the registration comprises finding the maximum of a similarity factor between the mask images and the at least one 2D image; e) generating a combination of the at least one 2D image and a projection of the vascular structure on the basis of the 3D+t image data according to the registration; and f) displaying the combination as a guiding vessel tree projection. Thus improved cardiac roadmapping in form of a topographical roadmapping is provided since the roadmapping is based on three-dimensional data.
摘要翻译：本发明涉及3D起源的心脏路线图。为了提高作为导航信息提供给用户的信息的准确性，对病人没有任何额外的负担，例如额外的X射线剂量，描述了一种方法，其包括以下步骤：a）提供a的3D + t图像数据物体的血管结构; b）获取所述对象的二维图像数据，所述对象包括所述血管结构，所述2D图像数据包括至少一个2D图像; c）投影血管结构，从而基于3D + t图像数据生成多个掩模图像; d）使用所述多个掩模图像之一注册所述至少一个2D图像，其中所述注册包括找到所述掩模图像与所述至少一个2D图像之间的相似性因子的最大值; e）根据所述注册，基于所述3D + t图像数据生成所述至少一个2D图像和所述血管结构的投影的组合; 以及f）将所述组合显示为引导血管树投影。因此，由于路线图基于三维数据，所以提供了形成地形路线图的改进的心脏路线图。

13. 发明申请

WO2011015957A1 METHOD AND APPARATUS FOR GENERATING COMPUTED TOMOGRAPHY IMAGES WITH OFFSET DETECTOR GEOMETRIES 审中-公开
标题翻译：用偏移检测器几何生成计算机图像的方法和装置
公开(公告)号：WO2011015957A1
公开(公告)日：2011-02-10
申请号：PCT/IB2010/053093
申请日：2010-07-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , SOWARDS-EMMERD, David , NORTMANN, Charles , HANSIS, Eberhard , GRASS, Michael
发明人： SOWARDS-EMMERD, David , NORTMANN, Charles , HANSIS, Eberhard , GRASS, Michael
IPC分类号： G06T11/00
CPC分类号： G06T11/006 , G06T2211/432
摘要： In accordance with one aspect of the invention a method and apparatus for generating complete scout scans with CT imaging devices having offset detector geometries is provided. In accordance with another aspect of the invention, a method and apparatus for increasing the reconstructable field of view for CT imaging devices having offset detector geometries is provided. In accordance with another aspect of the invention, a method and apparatus for image reconstruction for region of interest and full-body imaging with CT imaging devices having offset detector geometries is provided. In accordance with another aspect of the invention, a combined x-ray and SPECT imaging system is provided.
摘要翻译：根据本发明的一个方面，提供了一种用于产生具有偏移检测器几何形状的CT成像装置的完整侦察扫描的方法和装置。根据本发明的另一方面，提供了一种用于增加具有偏移检测器几何形状的CT成像装置的可重建视场的方法和装置。根据本发明的另一方面，提供了一种用于具有偏移检测器几何形状的CT成像装置的感兴趣区域和全身成像的图像重建方法和装置。根据本发明的另一方面，提供组合的x射线和SPECT成像系统。

14. 发明申请

WO2007138526A3 HIERARCHICAL MOTION ESTIMATION 审中-公开
公开(公告)号：WO2007138526A3
公开(公告)日：2007-12-06
申请号：PCT/IB2007/051915
申请日：2007-05-21
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , SCHÄFER, Dirk , ENGLER, Andreas , MOVASSAGHI, Babak , RASCHE, Volker , GRASS, Michael
发明人： SCHÄFER, Dirk , ENGLER, Andreas , MOVASSAGHI, Babak , RASCHE, Volker , GRASS, Michael
IPC分类号： A61B6/00 , A61B6/03 , G06T3/00 , G06T7/00 , G06T7/20
摘要： In three-dimensional rotational x-ray coronary imaging problems may arise when estimating the motion of small vessels. According to an exemplary embodiment of the present invention, an examination apparatus is provided which is adapted for performing a hierarchical motion estimation by global affine transformation for every heart phase, followed by vessel branch selective affine and non-affine transformations. This may provide for an improved image quality.

15. 发明申请

WO2007116329A1 DUAL SPECTRUM X-RAY TUBE WITH SWITCHED FOCAL SPOTS AND FILTER 审中-公开
标题翻译：双光谱X射线管与开关的焦点和过滤器
公开(公告)号：WO2007116329A1
公开(公告)日：2007-10-18
申请号：PCT/IB2007/050894
申请日：2007-03-15
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , GRASS, Michael , JENSEN, Dye , SCHÄFER, Dirk
发明人： GRASS, Michael , JENSEN, Dye , SCHÄFER, Dirk
IPC分类号： H01J35/30 , A61B6/03
CPC分类号： A61B6/032 , A61B6/4028 , A61B6/4035 , A61B6/4441 , A61B6/466 , A61B6/482 , A61B6/503 , A61B6/504 , A61B6/527 , G01N23/046 , G01N2223/419 , G01N2223/612 , H01J35/30
摘要： In three-dimensional computed tomography or three-dimensional rotational X-ray imaging, the acquisition of different spectral measurement data requires subsequent acquisition runs. According to an exemplary embodiment of the present invention, an examination apparatus is provided in which different spectral measurement data are acquired immediately one after another during the same acquisition run by performing a focal spot switching during data acquisition. This may reduce motion artefacts.
摘要翻译：在三维计算机断层扫描或三维旋转X射线成像中，采集不同的光谱测量数据需要随后的采集运行。根据本发明的示例性实施例，提供了一种检查装置，其中在相同的采集运行期间，通过在数据采集期间执行焦斑切换，立即一个接一个地获取不同的光谱测量数据。这可以减少运动伪影。

16. 发明申请

WO2006051442A1 ENERGY-RESOLVED COMPUTER TOMOGRAPHY 审中-公开
标题翻译：能量计算机图形学
公开(公告)号：WO2006051442A1
公开(公告)日：2006-05-18
申请号：PCT/IB2005/053564
申请日：2005-11-02
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , GRASS, Michael , KOEHLER, Thomas
发明人： GRASS, Michael , KOEHLER, Thomas
IPC分类号： A61B6/03
CPC分类号： A61B6/032 , A61B6/483 , G01T1/2985
摘要： In coherent scatter computed tomography, the scatter angle from object points (31, 32, 33, 34, 35), which are located on a line (36) perpendicular to the central beam (45) in the plane of rotation, varies as a non-linear function of the fan-angle of the detector row (37). According to an exemplary embodiment of the present invention, a single-line energy-resolved detector for CSCT data acquisition is used, which measures scattered photons originating from object points on a circular arc under the same scatter angle. This automatically leads to a Cartesian q- sampling on a parallel-rebinned detector. Advantageously, this may avoid q- interpolation prior to parallel-rebinned filtered back-projection reconstruction.
摘要翻译：在相干散射计算机断层摄影中，位于与旋转平面中的中心光束（45）垂直的线（36）上的物体点（31,32,33,34,35）的散射角随着检测器行（37）的扇角的非线性函数。根据本发明的示例性实施例，使用用于CSCT数据采集的单行能量分辨检测器，其测量源自圆弧上的物点的散射光子在相同的散射角下。这将自动导致在并行重组检测器上的笛卡尔q采样。有利地，这可以避免在并行重新组合的滤波反投影重建之前的q-内插。

17. 发明申请

WO2006003578A1 EXAMINATION APPARATUS FOR PERFUSION STUDIES 审中-公开
标题翻译：检查设备用于灌注研究
公开(公告)号：WO2006003578A1
公开(公告)日：2006-01-12
申请号：PCT/IB2005/052095
申请日：2005-06-24
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , GRASS, Michael , RASCHE, Volker
发明人： GRASS, Michael , RASCHE, Volker
IPC分类号： G06T11/00
CPC分类号： G06T11/005 , A61B6/027 , G06T2211/404 , G06T2211/412 , G06T2211/416
摘要： The invention relates to an examination apparatus and a method for perfusion studies in a patient (1). According to the method, a rotational X-ray device (10) is moved on a closed, preferably non-planar trajectory (T) while continuously generating projections of the patient (1) after the injection of a contrast agent with an injection device (20). The projections are used by a data processing system (30) in a sliding window technique to reconstruct three-dimensional images of the body volume. The resulting sequence of 3D images may be displayed on a monitor (31) to reveal the desired information about the perfusion process.
摘要翻译：本发明涉及一种用于患者（1）中的灌注研究的检查装置和方法。根据该方法，旋转X射线装置（10）在闭合的，优选非平面的轨迹（T）上移动，同时在用注射装置注射造影剂之后连续产生患者（1）的突起 20）。数据处理系统（30）在滑动窗口技术中使用投影来重建身体体积的三维图像。所得到的3D图像序列可以显示在监视器（31）上，以显示关于灌注过程的期望信息。

18. 发明申请

WO2003105017A3 ANALYSIS OF A MULTI-DIMENSIONAL STRUCTURE 审中-公开
公开(公告)号：WO2003105017A3
公开(公告)日：2003-12-18
申请号：PCT/IB2003/002161
申请日：2003-05-21
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , RASCHE, Volker , MOVASSAGHI, Babak , GRASS, Michael
发明人： RASCHE, Volker , MOVASSAGHI, Babak , GRASS, Michael
IPC分类号： G06T7/00
摘要： A method is provided for analysis of a multi-dimensional structure which includes a tubular structure from two-dimensional datasets for respective pre-determined projection directions. A pair of corresponding initial projected centre points of the tubular structure is identified in two respective initial and further two-dimensional datasets.Projected edges of the tubular structure in said initial two-dimensional datasets and in said further two-dimensional dataset near the respective projected centre points are identified. A local size of the tubular structure is derived at the three-dimensional spatial position of the centre point of the tubular structure from said projected edges and the predetermined projection directions.

19. 发明申请

WO2003085390A2 COMPUTED TOMOGRAPHY METHOD 审中-公开
标题翻译：计算机测图法
公开(公告)号：WO2003085390A2
公开(公告)日：2003-10-16
申请号：PCT/IB2003/001284
申请日：2003-04-09
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , GRASS, Michael , KOEHLER, Thomas , PROKSA, Roland
发明人： GRASS, Michael , KOEHLER, Thomas , PROKSA, Roland
IPC分类号： G01N23/00
CPC分类号： A61B6/032 , A61B6/027 , G01N23/046 , G01N2223/419 , G06T11/005 , Y10S378/901
摘要： The invention relates to a computed tomography method in which a rebinning operation is carried out so as to form parallel fan beams whose rays traverse a plane, containing the axis of rotation, in equidistant puncture points. Reconstruction is performed for rays which extend perpendicularly to said planes. Such a transition from a cone beam geometry to a parallel beam geometry enables very fast reconstruction which can be carried out notably for CT fluoroscopy.
摘要翻译：本发明涉及一种计算机断层摄影方法，其中进行重组操作以形成平行扇形束，其平行扇形束横穿包含旋转轴线的平面在等距穿刺点中。对垂直于所述平面延伸的射线进行重建。从锥形束几何形状到平行光束几何形状的这种过渡使得能够非常快速地重建，这可以用于CT荧光透视。

20. 发明申请

WO2003065894A1 SEQUENTIAL COMPUTED TOMOGRAPHY METHOD 审中-公开
标题翻译：顺序计算的TOMOGRAPHY方法
公开(公告)号：WO2003065894A1
公开(公告)日：2003-08-14
申请号：PCT/IB2003/000314
申请日：2003-01-30
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , GRASS, Michael , KÖHLER, Thomas
发明人： GRASS, Michael , KÖHLER, Thomas
IPC分类号： A61B6/03
CPC分类号： A61B6/032 , A61B6/027 , Y10S378/901
摘要： The invention relates to a computed tomography method in which an examination zone is irradiated from two mutually offset, preferably circular trajectories. In an intermediate region the absorption distribution is reconstructed by means of measuring values from both trajectories, the weight with which the measuring values are used being larger as the distance between the voxel to be reconstructed and the relevant trajectory is smaller.
摘要翻译：本发明涉及一种计算机断层摄影方法，其中从两个相互偏移，优选圆形轨迹照射检查区。在中间区域中，通过来自两个轨迹的测量值重建吸收分布，使用测量值的重量随着待重建的体素与相关轨迹之间的距离较小而变大。

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