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    • 14. 发明申请
    • CONFORMING ANCHOR FOR DUODENAL BARRIER
    • 适用于DUODENAL BARRIER的锚固器
    • WO2015031154A1
    • 2015-03-05
    • PCT/US2014/052090
    • 2014-08-21
    • ETHICON ENDO-SURGERY, INC.
    • HARRIS, Jason L.ZEINER, Mark S.DUNKI-JACOBS, Adam R.SHERRILL, Justin W.
    • A61F5/00
    • A61F5/0076A61F5/0079A61F5/0089
    • An apparatus comprises a sleeve, a seal, and an anchor assembly. The sleeve is flexible and non-permeable and is configured to fit in a duodenum. The seal is positioned at the proximal end of the sleeve and is configured to seal the proximal end of the sleeve against the stomach mucosa, the pylorus, or the duodenum mucosa. The anchor assembly comprises a pair of a traumatic anchor ends and a resilient member positioned between the anchor ends. At least a portion of the resilient member extends along at least a portion of the length of the sleeve. The resilient member is configured to bias the anchor ends generally toward each other, to thereby substantially anchor the sleeve in the duodenum. The sleeve is configured to prevent chyme from contacting the mucosa of the duodenum; and to prevent enzymes excreted in the duodenum from mixing with chyme in the duodenum.
    • 一种装置包括套筒,密封件和锚固组件。 套管是柔性的且不可渗透的并且被配置成适合于十二指肠。 密封件定位在套筒的近端处,并且构造成将套筒的近端密封抵靠胃粘膜,幽门或十二指肠粘膜。 锚固组件包括一对创伤性锚固端部和位于锚固端部之间的弹性构件。 弹性构件的至少一部分沿着套筒的长度的至少一部分延伸。 弹性构件构造成将锚固端部大致朝向彼此偏压,从而基本上将套管锚定在十二指肠中。 套筒构造成防止食糜接触十二指肠粘膜; 并防止在十二指肠中排泄的酶与十二指肠中的食糜混合。