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11. 发明申请

WO2018007970A1 A NATURAL COMPOSITION TO INHIBIT BETA-SECRETASE AND ENHANCE BIOAVAILABILITY COMPRISING OF TURMERIC AND SESAME SEED EXTRACT 审中-公开
标题翻译：一种抑制β-分泌酶并提高含有番茄和芝麻种子提取物的生物可利用性的自然组合物
公开(公告)号：WO2018007970A1
公开(公告)日：2018-01-11
申请号：PCT/IB2017/054072
申请日：2017-07-06
申请人： ANTONY, Benny
发明人： ANTONY, Benny
IPC分类号： A61K36/00 , A61K31/00
摘要： Compositions for inhibiting beta secretase activity are disclosed. Compositions that enhance bioavailability of curcumin, demethoxycurcumin, bisdemethoxycurcumin, α-turmerone, ar- turmerone, or, sesamolin are disclosed. Some compositions include a curcuminoid mixture and essential oil of turmeric having a-turmerone. Some compositions include a curcuminoid mixture and a combination, wherein the combination includes essential oil of turmeric having α-turmerone, and, an extract of sesame oil having sesamolin. Some compositions are a combination of essential oil of turmeric having α-turmerone, and, an extract of sesame oil having sesamolin. Methods of preparing the compositions are disclosed. Methods of treatment of central nervous system or neurological disorders are provided.
摘要翻译：公开了用于抑制β分泌酶活性的组合物。公开了增强姜黄素，去甲氧基姜黄素，双去甲氧基姜黄素，α-姜黄酮，阿莫酮或芝麻酚的生物利用度的组合物。一些组合物包含姜黄色素混合物和具有α-托莫酮的姜黄精油。一些组合物包含姜黄色素混合物和组合，其中所述组合包括具有α-turmerone的姜黄精油和具有芝麻酚的芝麻油提取物。一些组合物是具有α-turmerone的姜黄精油和具有芝麻素的芝麻油提取物的组合。公开了制备组合物的方法。提供了治疗中枢神经系统或神经系统疾病的方法。

12. 发明申请

WO2014207770A8 A MEDICINAL COMPOSITION OF AMARANTH EXTRACT ORIGIN HAVING ENRICHED NITRATE CONTENT AND A METHOD OF PREPARING THE SAME 审中-公开
公开(公告)号：WO2014207770A8
公开(公告)日：2014-12-31
申请号：PCT/IN2014/000430
申请日：2014-06-26
申请人： ANTONY, Benny
发明人： ANTONY, Benny
IPC分类号： A61K33/00 , A61K36/21 , A61K36/00
摘要： The invention discloses an extract of Amaranth, having enriched nitrate content, L-arginine, Flavonoids, saponins, alkaloids, carbohydrates, proteins, potassium, and with negligible amount of oxalic acid or oxalate content. The extract of Amaranth can be prepared from fresh or dried leaves and stem of Amaranth. It can be administered into different dosage viz. fast melt tablet, lozenge, candy, chewing gum, beverage, tablet, capsule, pill, and powder to patients. The said enriched extract of Amaranth has the capability to enhance nitric oxide concentration, nitrate level concentration, and nitrite level in blood as well as in saliva. Hence by administering it can lower blood pressure, increase physical endurance, increase swimming endurance, increase running endurance, and improve sexual performance among human beings.

13. 发明申请

WO2014207770A3 A MEDICINAL COMPOSITION OF AMARANTH EXTRACT ORIGIN HAVING ENRICHED NITRATE CONTENT AND A METHOD OF PREPARING THE SAME 审中-公开
公开(公告)号：WO2014207770A3
公开(公告)日：2014-12-31
申请号：PCT/IN2014/000430
申请日：2014-06-26
申请人： ANTONY, Benny
发明人： ANTONY, Benny
IPC分类号： A61K33/00 , A61K36/21 , A61K36/00
摘要： The invention discloses an extract of Amaranth, having enriched nitrate content, L-arginine, Flavonoids, saponins, alkaloids, carbohydrates, proteins, potassium, and with negligible amount of oxalic acid or oxalate content. The extract of Amaranth can be prepared from fresh or dried leaves and stem of Amaranth. It can be administered into different dosage viz. fast melt tablet, lozenge, candy, chewing gum, beverage, tablet, capsule, pill, and powder to patients. The said enriched extract of Amaranth has the capability to enhance nitric oxide concentration, nitrate level concentration, and nitrite level in blood as well as in saliva. Hence by administering it can lower blood pressure, increase physical endurance, increase swimming endurance, increase running endurance, and improve sexual performance among human beings.

14. 发明申请

WO2014111956A2 SUSTAINED RELEASE FORMULATIONS OF CURCUMINOIDS AND METHOD OF PREPARATION THEREOF 审中-公开
标题翻译：光泽剂的持续释放配方及其制备方法
公开(公告)号：WO2014111956A2
公开(公告)日：2014-07-24
申请号：PCT/IN2014/000031
申请日：2014-01-16
申请人： ANTONY, Benny
发明人： ANTONY, Benny
CPC分类号： A61K9/145 , A61K9/146 , A61K9/5047 , A61K36/9066
摘要： A sustained curcuminoid release pharmaceutical composition is provided. The sustained curcuminoid release composition includes bioavailable curcumin formulation and release rate controlling excipients such as ethyl cellulose, shellac, copolymer of ethyl acrylate and methyl methacrylate, acrylic acid copolymers, hydroxy propyl methyl cellulose (HPMC), hydroxy propyl cellulose. A process for the manufacturing of sustained release curcuminoid formulations is provided.
摘要翻译：提供持久的姜黄素类释放药物组合物。持续的姜黄素释放组合物包括生物可利用的姜黄素制剂和释放速率控制赋形剂如乙基纤维素，虫胶，丙烯酸乙酯和甲基丙烯酸甲酯的共聚物，丙烯酸共聚物，羟丙基甲基纤维素（HPMC），羟丙基纤维素。提供了制备缓释姜黄素制剂的方法。

15. 发明申请

WO2014068597A2 FORMULATION OF CURCUMIN WITH ENHANCED BIOAVAILABILITY OF CURCUMIN AND METHOD OF PREPARATION AND TREATMENT THEREOF 审中-公开
标题翻译：具有增强的姜黄素生物利用度的姜黄素的制剂及其制备和处理方法
公开(公告)号：WO2014068597A2
公开(公告)日：2014-05-08
申请号：PCT/IN2013/000673
申请日：2013-10-31
申请人： ANTONY, Benny
发明人： ANTONY, Benny , KURIAKOSE, Moni Abraham
CPC分类号： A61K31/12 , A61K9/1664 , A61K9/4808 , A61K36/9066 , A61K2300/00
摘要： Invention relates to a medicinal composition useful for the treatment of head and neck cancer premalignant lesions comprising a) curcuminoid mixture and b) an essential oil of turmeric, wherein said curcuminoid mixture consists of curcumin, demethoxycurcumin and bisdemethoxycurcumin, and said essential oil of turmeric consists of about 45% ar-turmerone. The weight ratio of curcuminoid mixture to essential oil of turmeric is ranging from about 1 :3 to about 99: 1. The invention also provides a method of preparation of the said composition and its efficacy in the treatment of head and neck cancer premalignant lesions by oral administration.
摘要翻译：本发明涉及用于治疗头颈癌癌前病变的药物组合物，其包含a）类姜黄素混合物和b）姜黄精油，其中所述类姜黄素混合物由姜黄素，去甲氧基姜黄素和双去甲氧基姜黄素，姜黄精油含有约45％的ar-turmerone。姜黄素混合物与姜黄精油的重量比为约1:3至约99:1。本发明还提供了一种制备所述组合物的方法及其在治疗头颈癌癌前病变中的功效口服给药。

16. 发明申请

WO2004078190A1 A PROCESS AND TECHNIQUE TO ELEVATE SERUM HIGH DENSITY LIBOPROTEIN 审中-公开
标题翻译：加强血清高密度脂蛋白的方法和技术
公开(公告)号：WO2004078190A1
公开(公告)日：2004-09-16
申请号：PCT/IN2003/000137
申请日：2003-04-03
申请人： ANTONY, Benny
发明人： ANTONY, Benny
IPC分类号： A61K35/78
CPC分类号： A61K36/47 , A61K36/185 , A61K36/78
摘要： This invention relates to an innovative and path breaking technique (2 to 4) that elevates high-density libo protein (HDL) serum and enhances its efficacy to prevent accumulation of Cholesterol in the tissues. The inventive step (1) is also epitomized in an Eco-friendly method and manner of extracting (2) a standardized and efficacious vegetable phytosterol of Embilica Officinalis dispensable in free flowing ingestible granules (5 and 6). The effect of the invention on cholesterol build up is made under claims (6 to 8).
摘要翻译：本发明涉及提高高密度脂蛋白（HDL）血清的创新和路径破坏技术（2至4），并提高其预防胆固醇在组织中积累的功效。本发明的步骤（1）还以环保方式和提取方式（2）标准化和有效的可自由流动的可摄取颗粒（5和6）中的Emblica Officinalis植物甾醇的植物甾醇代谢。本发明对胆固醇积聚的作用是根据权利要求（6至8）进行的。

17. 发明申请

WO2019097417A2 A PHARMACEUTICAL COMPOSITION MADE FROM HYDROPHOBIC PHYTOCHEMICALS DISPERSED IN SESAME OIL TO ENHANCE BIOACTIVITY 审中-公开
公开(公告)号：WO2019097417A2
公开(公告)日：2019-05-23
申请号：PCT/IB2018/058948
申请日：2018-11-14
申请人： ANTONY, Benny
发明人： ANTONY, Benny
IPC分类号： A61K36/324
CPC分类号： A61K36/324 , A61K9/00 , A61K9/08 , A61K9/10 , A61K36/185 , A61K36/9066 , A61K47/44 , A61K2300/00
摘要： Pharmaceutical formulations and methods to increase the bioactivity and bioavailability of plant compound having hydrophobic phytochemicals which have poor bioavailability due to poor water solubility. Dispersions of extracts of Boswellia and/or Curcuma longa in sesame seed oil. Analgesic and anti-inflammatory composition having a) an extract of Boswellia, b) one or more of an extract of Curcuma longa, a curcuminoid composition and combinations thereof, and, c) a sesame seed oil. The analgesic and anti-inflammatory composition has particles having a particle size ranging from less than about 20 micrometers to about 1 micrometer. The analgesic and anti- inflammatory composition provides a total combined specific surface area provided by particles in the composition ranging from about 900 meter 2 per kilogram to about 3000 meter 2 per kilogram of the composition. Methods of preparing the compositions and methods of treating inflammation and musculoskeletal disorders are provided.

18. 发明申请

WO2019038681A3 NATURAL FOOD PRESERVATIVE FORMULATION 审中-公开
公开(公告)号：WO2019038681A3
公开(公告)日：2019-02-28
申请号：PCT/IB2018/056337
申请日：2018-08-22
申请人： ANTONY, Benny
发明人： ANTONY, Benny
IPC分类号： A01N65/22 , A01N65/24 , A01N65/28 , A23L3/3463 , A23L3/3472
摘要： A natural food preservative formulation to prevent microbial spoilage and oxidative damage in a food article. The natural preservative includes constituents derived mainly from plants, such as essential oils and organic acids and plant extract. Combination of different plant derived constituents to form different natural preservative formulations are disclosed. Tailor made formulation for specific food material is also disclosed. Methods for preparing the food preservative and application of the food preservative formulation into different food article/products are also disclosed.

19. 发明申请

WO2019025993A3 MEDICINAL COMPOSITION OF AMARANTH ORIGIN FOR CARDIOVASCULAR TREATMENT 审中-公开
公开(公告)号：WO2019025993A3
公开(公告)日：2019-02-07
申请号：PCT/IB2018/055773
申请日：2018-08-01
申请人： ANTONY, Benny
发明人： ANTONY, Benny
IPC分类号： A61K36/21 , A61K36/906 , A61K36/9066
摘要： A medicinal composition having a nitrate enriched extract of Amaranth for the prevention and treatment of myocardial ischemia-reperfusion injury, and for the improvement of cardioprotective health and cardio renal protection. A method for the prevention and treatment of myocardial ischemia-reperfusion injury, method of improving cardioprotective health and cardio renal protection by using the composition having a nitrate enriched extract of Amaranth.

20. 发明申请

WO2019025993A2 MEDICINAL COMPOSITION OF AMARANTH ORIGIN FOR CARDIOVASCULAR TREATMENT 审中-公开
公开(公告)号：WO2019025993A2
公开(公告)日：2019-02-07
申请号：PCT/IB2018/055773
申请日：2018-08-01
申请人： ANTONY, Benny
发明人： ANTONY, Benny
IPC分类号： A61K36/185 , A61K33/00
CPC分类号： A61K36/21 , A61K33/00 , A61K36/185 , A61K36/9066 , A61K2300/00
摘要： A medicinal composition having a nitrate enriched extract of Amaranth for the prevention and treatment of myocardial ischemia-reperfusion injury, and for the improvement of cardioprotective health and cardio renal protection. A method for the prevention and treatment of myocardial ischemia-reperfusion injury, method of improving cardioprotective health and cardio renal protection by using the composition having a nitrate enriched extract of Amaranth.

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