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11. 发明申请

WO2012154154A1 HIGHER RESOLUTION STILL IMAGE GENERATION FROM LOWER RESOLUTION VIDEO CAMERA FRAMES 审中-公开
标题翻译：更高分辨率下降分辨率视频相机框架的图像生成
公开(公告)号：WO2012154154A1
公开(公告)日：2012-11-15
申请号：PCT/US2011/035490
申请日：2011-05-06
申请人： EMPIRE TECHNOLOGY DEVELOPMENT LLC , LEUNG, Henry , LIU, Xiaoxiang
发明人： LEUNG, Henry , LIU, Xiaoxiang
IPC分类号： G06K9/32
CPC分类号： H04N5/23232 , G06T3/4053 , H04N5/2254
摘要： Technologies are generally described herein for generating a higher resolution still frame. Some example technologies may configure a video camera at a first configuration, which the video camera to capture video at a first pixel offset. The technologies may capture a first frame of a field-of-view through the video camera configured at the first configuration. The first frame may contain the field-of-view captured at the first pixel offset. The technologies may adjust the video camera from the first configuration to a second configuration, which adapts the video camera to capture the video at a second pixel offset, the adjustment using a hardware mechanism. The technologies may capture a second frame of the field-of-view through the video camera configured at the second configuration. The second frame may contain the field-of-view captured at the second pixel offset.
摘要翻译：这里通常描述了用于产生更高分辨率静止帧的技术。一些示例性技术可以以第一配置配置摄像机，其中摄像机以第一像素偏移捕获视频。这些技术可以通过在第一配置配置的摄像机捕获视场的第一帧。第一帧可以包含在第一像素偏移处捕获的视场。这些技术可以将摄像机从第一配置调整到第二配置，其适配摄像机以第二像素偏移捕获视频，使用硬件机制进行调整。这些技术可以通过在第二配置下配置的摄像机捕获视场的第二帧。第二帧可以包含在第二像素偏移处捕获的视场。

12. 发明申请

WO2011152902A1 BROADBAND PASSIVE TRACKING FOR AUGMENTED REALITY 审中-公开
标题翻译：宽带无源跟踪适用于现实
公开(公告)号：WO2011152902A1
公开(公告)日：2011-12-08
申请号：PCT/US2011/026298
申请日：2011-02-25
申请人： EMPIRE TECHNOLOGY DEVELOPMENT LLC , LEUNG, Henry , LIU, Xiaoxiang
发明人： LEUNG, Henry , LIU, Xiaoxiang
IPC分类号： G01S13/00 , G06F19/00 , H04W4/02
CPC分类号： G06T7/0042 , G06T7/246 , G06T7/73 , G06T19/006 , H04N5/225 , H04N7/18
摘要： Technologies are generally described for a broadband passive sensing and tracking system that may employ a number of passive receivers that each have the capability of sensing electromagnetic waves (e.g., Radio Frequency "RF" signals) from surrounding broadcast sources. Each passive receiver may be adapted to sense through one or more antennas. Multiple receivers at different positions may be utilized to form a broadband sensing network adapted to perform collaborative tracking of a scene of interest. According to some examples, a beam-forming algorithm may be applied over the broadband sensing network utilizing an antenna array formed by the passive receivers to localize and track objects.
摘要翻译：技术通常被描述用于宽带被动感测和跟踪系统，其可以使用多个无源接收机，每个被动接收机具有感测来自周围广播源的电磁波（例如，射频“RF”信号）的能力。每个无源接收机可以适于通过一个或多个天线进行感测。可以利用不同位置处的多个接收器来形成适于执行感兴趣的场景的协作跟踪的宽带感测网络。根据一些示例，波束形成算法可以利用由无源接收器形成的天线阵列在宽带感测网络上应用，以定位和跟踪对象。

13. 发明申请

WO2008103351A2 HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS 审中-公开
标题翻译：异源ASPARTYL蛋白酶抑制剂
公开(公告)号：WO2008103351A2
公开(公告)日：2008-08-28
申请号：PCT/US2008/002182
申请日：2008-02-20
申请人： SCHERING CORPORATION , PHARMACOPEIA, INC. , ZHU, Zhaoning , MCKITTRICK, Brian , SUN, Zhong-Yue , YE, Yuanzan, C. , VOIGT, Johannes, H. , STRICKLAND, Corey , SMITH, Elizabeth, M. , STAMFORD, Andrew , GREENLEE, William, J. , MAZZOLA, JR., Robert, D. , CALDWELL, John , CUMMING, Jared, N. , WANG, Lingyan , WU, Yusheng , ISERLOH, Ulrich , LIU, Xiaoxiang , HUANG, Ying , LI, Guoqing , PAN, Jianping , MISIASZEK, Jeffrey, A. , GUO, Tao , LE, Thuy X. H. , SAIONZ, Kurt, W. , BABU, Suresh, D. , HUNTER, Rachael, C. , MORRIS, Michelle, L. , GU, Huizhong , QIAN, Gang , TADESSE, Dawit , LAI, Gaifa , DUO, Jingqi , QU, Chuanxing , SHAO, Yuefei
发明人： ZHU, Zhaoning , MCKITTRICK, Brian , SUN, Zhong-Yue , YE, Yuanzan, C. , VOIGT, Johannes, H. , STRICKLAND, Corey , SMITH, Elizabeth, M. , STAMFORD, Andrew , GREENLEE, William, J. , MAZZOLA, JR., Robert, D. , CALDWELL, John , CUMMING, Jared, N. , WANG, Lingyan , WU, Yusheng , ISERLOH, Ulrich , LIU, Xiaoxiang , HUANG, Ying , LI, Guoqing , PAN, Jianping , MISIASZEK, Jeffrey, A. , GUO, Tao , LE, Thuy X. H. , SAIONZ, Kurt, W. , BABU, Suresh, D. , HUNTER, Rachael, C. , MORRIS, Michelle, L. , GU, Huizhong , QIAN, Gang , TADESSE, Dawit , LAI, Gaifa , DUO, Jingqi , QU, Chuanxing , SHAO, Yuefei
IPC分类号： C07D233/88 , C07D239/22 , C07D401/06 , C07D409/04 , C07D409/14 , C07D413/04 , C07D417/14 , C07D495/10 , C07D401/10 , C07D417/10 , A61K31/513 , A61P25/28
CPC分类号： C07D233/88 , A61K31/4168 , A61K31/4178 , C07D239/22 , C07D401/06 , C07D401/10 , C07D403/06 , C07D409/04 , C07D409/14 , C07D413/04 , C07D417/10 , C07D417/14 , C07D495/10
摘要： Disclosed are compounds of the formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein W is a bond, -C(=S)-, -S(O)-, -S(O) 2 -, -C(=O)-, -O-, -C(R 6 )(R 7 )-, -N(R 5 )- or -C(=N(R 5 ))-; X is -O-, -N(R 5 )- or -C(R 6 )(R 7 )-; provided that when X is -O-, U is not -O-, -S(O)-, -S(O) 2 -, -C(=O)- or -C(=NR 5 )-; U is a bond, -S(O)-, -S(O) 2 -, -C(O)-, -O-, -P(O)(OR 15 )-, -C(=NR 5 )-, -(C(R 6 )(R 7 )) b - or -N(R 5 )-; wherein b is 1 or 2; provided that when W is -S(O)-, -S(O) 2 -, -O-, or -N(R 5 )-, U is not -S(O)-, -S(O) 2 -, -O-, or -N(R 5 )-; provided that when X is -N(R 5 )- and W is -S(O)-, -S(O) 2 -, -O-, or -N(R 5 )-, then U is not a bond; and R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , and R 7 are as defined in the specification; and pharmaceutical compositions comprising the compounds of formula (I). Also disclosed is the method of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases, and the methods of inhibiting of Human Immunodeficiency Virus, plasmepins, cathepsin D and protozoal enzymes. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula I in combination with a cholinesterase inhibitor or a muscarinic m 1 agonist or m 2 antagonist.
摘要翻译：公开了式（I）化合物或其立体异构体，互变异构体或其药学上可接受的盐或溶剂化物，其中W为键，-C（= S） - ， - S（O） - ， - S（O） -C（= O） - ， - O - ， - （R 6） - （R 7） - ， - N（ R 5） - 或-C（= N（R 5）） - ; X是-O-，-N（R 5） - 或-C（R 6）（R 7）。条件是当X是-O-时，U不是-O-，-S（O） - ， - S（O）2 - ， - C（= O） - 或-C（= NR ^{5 ） - ; U是一个键，-S（O） - ， - S（O）2 - ， - C（O） - ， - O - ，-P（O）（C（R 6）） - ， - （C（R 6）） - ， - C（= NR 5） > - 或-N（R 5） - ; 其中b为1或2; 条件是当W是-S（O） - ， - S（O）2 - ， - O-或-N（R 5）时，U不是 -S（O） - ， - S（O）2 - ， - O-或-N（R 5））。条件是当X是-N（R 5） - 且W是-S（O） - ，-S（O）2 - ， - O-或 - N（R 5） - ，则U不是键; 和R 1，R 2，R 3，R 4，R 5， R 6，R 6和R 7如说明书中所定义; 和包含式（I）化合物的药物组合物。还公开了抑制天冬氨酰蛋白酶的方法，特别是治疗心血管疾病，认知和神经退行性疾病的方法，以及抑制人类免疫缺陷病毒，plasmepins，组织蛋白酶D和原生动物酶的方法。还公开了使用式I化合物与胆碱酯酶抑制剂或毒蕈碱m 1激动剂或m 2 H 2拮抗剂组合治疗认知或神经变性疾病的方法。}

14. 发明申请

WO2007075783A2 SUBSTITUTED ISOQUINOLINE-1,3(2H,4H)-DIONES, 1-THIOXO-1,4-DIHYDRO-2H-ISOQUINOLINE-3-ONES AND 1,4-DIHYDRO-3(2H)-ISOQUINOLONES AND METHODS OF USE THEREOF 审中-公开
标题翻译：取代的异喹啉-1,3-（2H，4H） - 酮，1-硫代-1,4-二氢-2H-异喹啉-3-酮和1,4-二氢-3（2H） - 异喹啉及其使用方法
公开(公告)号：WO2007075783A2
公开(公告)日：2007-07-05
申请号：PCT/US2006048603
申请日：2006-12-20
申请人： WYETH CORP , TSOU HWEI-RU , AYRAL-KALOUSTIAN SEMIRAMIS , BIRNBERG GARY HAROLD , FLOYD MIDDLETON BRAWNER , KAPLAN JOSHUA , KUTTERER KRISTINA M K , LIU XIAOXIANG , NILAKANTAN RAMASWAMY , OTTENG MERCY ADUFA , TANG ZHILIAN , ZASK ARIE , REICH MARVIN , TRAN TRITAN
发明人： TSOU HWEI-RU , AYRAL-KALOUSTIAN SEMIRAMIS , BIRNBERG GARY HAROLD , FLOYD MIDDLETON BRAWNER , KAPLAN JOSHUA , KUTTERER KRISTINA M K , LIU XIAOXIANG , NILAKANTAN RAMASWAMY , OTTENG MERCY ADUFA , TANG ZHILIAN , ZASK ARIE , REICH MARVIN , TRAN TRITAN
CPC分类号： C07D217/24 , C07D237/28 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/12 , C07D405/14 , C07D409/04 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/12 , C07D417/04 , C07D417/06 , C07D417/12 , C07D487/04
摘要： This invention provides compounds of Formula (I), having the structure where G 1 , G 2 , G 3 , G 4 , A 1 , A 2 , Y 1 , Y 2 , L 1 , Z, e and f are defined herein, or a pharmaceutically acceptable salt thereof, which are useful for treating or preventing cancer.
摘要翻译：本发明提供式（I）化合物，其具有如下结构：其中G 1，G 2，G 3，G 4， / SUP>，A 1，A 2，Y 1，Y 2，L 1， / SUP>，Z，e和f如本文所定义，或其药学上可接受的盐，其可用于治疗或预防癌症。

15. 发明申请

WO2006138264A3 ASPARTYL PROTEASE INHIBITORS 审中-公开
标题翻译： ASPARTYL PROTEASE抑制剂
公开(公告)号：WO2006138264A3
公开(公告)日：2007-03-01
申请号：PCT/US2006022918
申请日：2006-06-12
申请人： SCHERING CORP , ZHU ZHAONING , MCKITTRICK BRIAN , STAMFORD ANDREW , GREENLEE WILLIAM J , LIU XIAOXIANG , MANDAL MIHIRBARAN , VOIGT JOHANNES H , STRICKLAND COREY
发明人： ZHU ZHAONING , MCKITTRICK BRIAN , STAMFORD ANDREW , GREENLEE WILLIAM J , LIU XIAOXIANG , MANDAL MIHIRBARAN , VOIGT JOHANNES H , STRICKLAND COREY
IPC分类号： C07D487/04 , A61K31/519 , A61P25/28
CPC分类号： C07D487/04
摘要： Disclosed are compounds of the formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein j, k, U, W, R, R 1 , R 2 , R 3 , R 4 , R 6 , R 7 and R 7a are as described above in the specification. Also disclosed is the method of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula (I) in combination with a cholinesterase inhibitor or a muscarinic m1 agonist or m 2 antagonist.
摘要翻译：公开了式（I）化合物或其立体异构体，互变异构体或其药学上可接受的盐或溶剂化物，其中j，k，U，W，R，R 1，R 2， R 3，R 4，R 4，R 6，R 7和R 7， / SUP>如上文在说明书中所述。还公开了抑制天冬氨酰蛋白酶的方法，特别是治疗心血管疾病，认知和神经变性疾病的方法。还公开了使用式（I）化合物与胆碱酯酶抑制剂或毒蕈碱m1激动剂或m 2拮抗剂组合治疗认知或神经变性疾病的方法。

16. 发明申请

WO2014025344A3 REAL-TIME COMPRESSIVE DATA COLLECTION FOR CLOUD MONITORING 审中-公开
公开(公告)号：WO2014025344A3
公开(公告)日：2014-02-13
申请号：PCT/US2012/049884
申请日：2012-08-08
申请人： EMPIRE TECHNOLOGY DEVELOPMENT, LLC , LEUNG, Henry , LIU, Xiaoxiang
发明人： LEUNG, Henry , LIU, Xiaoxiang
IPC分类号： H04L12/26
摘要： Technologies are presented for implementing a compressive-sensing-based data collection system in a cloud environment. In some examples, high-dimensional sensor data may be compressed using sparsity transforms and compressive sampling. The resulting low-dimensional data messages may be steered through a switch network to a cloud service manager, which then reconstructs the compressed messages for subsequent analysis, reporting, and/or comparable actions.

17. 发明申请

WO2014025344A2 REAL-TIME COMPRESSIVE DATA COLLECTION FOR CLOUD MONITORING 审中-公开
标题翻译：用于云端监控的实时压缩数据收集
公开(公告)号：WO2014025344A2
公开(公告)日：2014-02-13
申请号：PCT/US2012049884
申请日：2012-08-08
申请人： EMPIRE TECHNOLOGY DEV LLC , LEUNG HENRY , LIU XIAOXIANG
发明人： LEUNG HENRY , LIU XIAOXIANG
IPC分类号： H04L12/26
CPC分类号： H04L69/04 , H04L41/142 , H04L41/5012 , H04L41/5096 , H04L43/08 , H04L43/10 , H04L43/12
摘要： Technologies are presented for implementing a compressive-sensing-based data collection system in a cloud environment. In some examples, high-dimensional sensor data may be compressed using sparsity transforms and compressive sampling. The resulting low-dimensional data messages may be steered through a switch network to a cloud service manager, which then reconstructs the compressed messages for subsequent analysis, reporting, and/or comparable actions.
摘要翻译：介绍了在云环境中实施基于压缩感测的数据收集系统的技术。在一些示例中，可以使用稀疏变换和压缩采样来压缩高维传感器数据。所产生的低维度数据消息可以通过交换网络引导至云服务管理器，然后云服务管理器重建压缩的消息以用于随后的分析，报告和/或类似的动作。

18. 发明申请

WO2010056849A1 GAMMA SECRETASE MODULATORS 审中-公开
标题翻译： GAMMA秘密调节器
公开(公告)号：WO2010056849A1
公开(公告)日：2010-05-20
申请号：PCT/US2009/064190
申请日：2009-11-12
申请人： SCHERING CORPORATION , ZHU, Zhaoning , GREENLEE, William J. , HUANG, Xianhai , QIN, Jun , LIU, Xiaoxiang , LI, Hongmei , ZHOU, Wei , PALANI, Anandan , ZHU, Xiaohong , VICAREL, Monica L. , MANDAL, Mihirbaran , SUN, Zhong-Yue , BENNETT, Chad E. , MCCRACKEN, Troy M. , GALLO, Gioconda
发明人： ZHU, Zhaoning , GREENLEE, William J. , HUANG, Xianhai , QIN, Jun , LIU, Xiaoxiang , LI, Hongmei , ZHOU, Wei , PALANI, Anandan , ZHU, Xiaohong , VICAREL, Monica L. , MANDAL, Mihirbaran , SUN, Zhong-Yue , BENNETT, Chad E. , MCCRACKEN, Troy M. , GALLO, Gioconda
IPC分类号： C07D471/04 , C07D498/04 , A61K31/5395 , A61P25/28
CPC分类号： C07D471/04 , C07D498/04
摘要： In its many embodiments, the present invention provides a novel class of heterocyclic compounds of Group A or Group, as defined herein, as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.
摘要翻译：在其许多实施方案中，本发明提供了一类新颖的本文所定义的组A或组的杂环化合物作为γ-分泌酶的调节剂，制备此类化合物的方法，含有一种或多种此类化合物的药物组合物，制备药物的方法包含一种或多种这样的化合物的制剂，以及使用这些化合物或药物组合物治疗，预防，抑制或改善与中枢神经系统相关的一种或多种疾病的方法。

19. 发明申请

WO2009131975A1 PHENYL-SUBSTITUTED 2-IMINO-3-METHYL PYRROLO PYRIMIDINONE COMPOUNDS AS BACE-1 INHIBITORS, COMPOSITIONS, AND THEIR USE 审中-公开
标题翻译：作为BACE-1抑制剂，组合物及其使用的苯基取代的2-亚氨基-3-甲基吡咯啉吡啶酮化合物
公开(公告)号：WO2009131975A1
公开(公告)日：2009-10-29
申请号：PCT/US2009/041202
申请日：2009-04-21
申请人： SCHERING CORPORATION , STAMFORD, Andrew, W. , ZHU, Zhaoning , MANDAL, Mihirbaran , WU, Yusheng , CUMMING, Jared, N. , LIU, Xiaoxiang , LI, Guoqing , ISERLOH, Ulrich
发明人： STAMFORD, Andrew, W. , ZHU, Zhaoning , MANDAL, Mihirbaran , WU, Yusheng , CUMMING, Jared, N. , LIU, Xiaoxiang , LI, Guoqing , ISERLOH, Ulrich
IPC分类号： C07D487/04 , A61P25/28 , A61K31/519
CPC分类号： C07D487/04
摘要： In its many embodiments, the present invention provides provides certain 2-imino-3-methyl pyrrolo pyrimidone compounds, including compounds Formula (II): and include tautomers, steroisomers, or pharmaceutically acceptable salts or solvates of said compounds, stereoisomers, or said tautomers, wherein R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , and R 9 are each selected independently and as defined herein. Pharmaceutical compositions comprising one or more such compounds, and methods for their preparation and use in treating pathologies associated with amyloid beta (Aβ) protein, including Alzheimer's Disease, are also disclosed.
摘要翻译：在其许多实施方案中，本发明提供某些2-亚氨基-3-甲基吡咯并嘧啶化合物，包括式（II）化合物：并且包括所述化合物，立体异构体或所述互变异构体的互变异构体，立体异构体或药学上可接受的盐或溶剂合物其中R2，R3，R4，R5，R6，R7，R8和R9各自独立地并如本文所定义。还公开了包含一种或多种这样的化合物的药物组合物及其制备和用于治疗与淀粉样蛋白β（Aβ）蛋白质（包括阿尔茨海默病）相关的病理学的方法。

20. 发明申请

WO2006138264A2 ASPARTYL PROTEASE INHIBITORS 审中-公开
标题翻译： ASPARTYL PROTEASE抑制剂
公开(公告)号：WO2006138264A2
公开(公告)日：2006-12-28
申请号：PCT/US2006/022918
申请日：2006-06-12
申请人： SCHERING CORPORATION , ZHU, Zhaoning , MCKITTRICK, Brian , STAMFORD, Andrew , GREENLEE, William, J. , LIU, Xiaoxiang , MANDAL, Mihirbaran , VOIGT, Johannes, H. , STRICKLAND, Corey
发明人： ZHU, Zhaoning , MCKITTRICK, Brian , STAMFORD, Andrew , GREENLEE, William, J. , LIU, Xiaoxiang , MANDAL, Mihirbaran , VOIGT, Johannes, H. , STRICKLAND, Corey
IPC分类号： C07D487/04 , A61K31/519 , A61P25/28
CPC分类号： C07D487/04
摘要： Disclosed are compounds of the formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein j, k, U, W, R, R 1 , R 2 , R 3 , R 4 , R 6 , R 7 and R 7a are as described above in the specification. Also disclosed is the method of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula (I) in combination with a cholinesterase inhibitor or a muscarinic m1 agonist or m 2 antagonist.
摘要翻译：公开了式（I）化合物或其立体异构体，互变异构体或其药学上可接受的盐或溶剂化物，其中j，k，U，W，R，R 1，R 2， R 3，R 4，R 4，R 6，R 7和R 7， / SUP>如上文在说明书中所述。还公开了抑制天冬氨酰蛋白酶的方法，特别是治疗心血管疾病，认知和神经变性疾病的方法。还公开了使用式（I）化合物与胆碱酯酶抑制剂或毒蕈碱m1激动剂或m2拮抗剂组合治疗认知或神经退行性疾病的方法。

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