专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO02090934A2 EVALUATION OF ULTRAVIOLET RADIATION DAMAGE TO SKIN USING NEW GENEMARKERS, METHODS AND COMPOSITIONS RELATED THERETO 审中-公开
标题翻译：使用新的生物标志物评估超紫外线对皮肤的损伤，方法和组合物
公开(公告)号：WO02090934A2
公开(公告)日：2002-11-14
申请号：PCT/US0214884
申请日：2002-05-09
申请人： UNIV CLEVELAND HOSPITALS , JONES BRIAN C , BOSKO CAROL , COOPER KEVIN , MCCORMICK THOMAS
发明人： JONES BRIAN C , BOSKO CAROL , COOPER KEVIN , MCCORMICK THOMAS
IPC分类号： G01N33/50 , A23L33/00 , A61K45/00 , A61P17/16 , C07H21/04 , C12N15/01 , C12N15/09 , C12Q1/02 , C12Q1/68 , G01N20060101 , G01N33/15 , G01N33/53 , G01N33/58 , G01N37/00 , G01N
CPC分类号： C12Q1/6883 , C12Q1/6886 , C12Q2600/158
摘要： The present invention describes a method for treating and/or evaluating photodamage and/or photoaging of skin caused by exposure to solar ultraviolet (UV) radiation. The method employs a unique set of marker genes whose expression was newly found to be altered following exposure of skin to UV radiation. The invention provides an advantageous system of identifying and assessing substances that are capable of modulating, e.g., via attenuation, UV radiation induced alteration or change in the expression of at least one of the newly provided marker genes in skin relative to the gene expression level in skin not exposed to UV radiation. Also provided are compositions comprising materials that upon application to skin can modulate the gene expression of at least one gene of the marker gene set after exposure of skin to UV radiation, thereby affording protective and therapeutic effects and treatments for photodamage and photoaging. The potential benefit of, e.g., skincare, hair care, cosmetic, and personal care agents, and nutritional supplements, as materials having antiphotodamage and/or antiphotoaging properties can be assessed using the present method.
摘要翻译：本发明描述了一种用于治疗和/或评估由暴露于太阳紫外线（UV）辐射引起的皮肤光损伤和/或光老化的方法。该方法采用独特的一组标记基因，其表达在皮肤暴露于紫外线辐射后被新发现被改变。本发明提供了一种鉴定和评估能够通过衰减，UV辐射诱导的改变或皮肤中至少一种新提供的标记基因在表达中相对于基因表达水平进行调节的物质的有利系统皮肤未暴露于紫外线辐射。还提供了包含施用于皮肤的材料的组合物，其可以在将皮肤暴露于UV辐射后调节标记基因集合的至少一个基因的基因表达，由此提供光损伤和光老化的保护和治疗效果和治疗。可以使用本发明的方法来评估例如护肤品，头发护理剂，化妆品和个人护理剂以及营养补充剂作为具有防重染性和/或抗重复性能的材料的潜在益处。

2. 发明申请

WO0015543A9 BEVERAGE DISPENSER 审中-公开
标题翻译：饮料分配器
公开(公告)号：WO0015543A9
公开(公告)日：2000-08-17
申请号：PCT/US9921021
申请日：1999-09-14
申请人： IMI CORNELIUS INC , JONES BRIAN C , SULLIVAN SCOTT J , CURRIER PETER J , DUCHENE RUSSELL J , FAROOQUI AMIR , ROTHWELL TIMOTHY C , ROGALA ALLEN L
发明人： JONES BRIAN C , SULLIVAN SCOTT J , CURRIER PETER J , DUCHENE RUSSELL J , FAROOQUI AMIR , ROTHWELL TIMOTHY C , ROGALA ALLEN L
IPC分类号： B67D1/00 , B67D1/08 , B67D5/56 , B67D5/62
CPC分类号： B67D1/0872 , B67D1/0864 , B67D2210/00039
摘要： The present invention is a beverage dispenser (10) that can be assembled virtually entirely by hand without the need for hand or power tools. Exterior cladding panels (14, 50, 52, 54 and 70) thereof provide for interlocking assembly. A new ice bank evaporator structure (46), baffle (28) and method of ice bank control are also shown. In addition, dispenser (10) includes a merchandising cover (100) that permits for quick low cost conversion from an opaque display to one utilizing a back-lit transparency (120). Dispenser (10) further includes a molded plastic box (146) releasably securable to the base panel (14) thereof for retaining syrup pumps (134) therein for permitting quick access thereto.
摘要翻译：本发明是一种饮料分配器（10），其可以几乎完全由手工组装而不需要手动或电动工具。其外部覆盖板（14,50,52,54和70）提供互锁组件。还显示了一个新的冰库蒸发器结构（46），挡板（28）和冰库控制方法。此外，分配器（10）包括商品外壳（100），其允许从不透明显示器到使用背光透明度（120）的快速低成本转换。分配器（10）还包括可释放地固定到其底板（14）上的模制塑料盒（146），用于将糖浆泵（134）保持在其中以便快速进入其中。

3. 发明申请

WO2006069072A2 METHOD AND COMPOSITION FOR REDUCING THE APPEARANCE OF WRINKLES 审中-公开
标题翻译：减少皱纹外观的方法和组合物
公开(公告)号：WO2006069072A2
公开(公告)日：2006-06-29
申请号：PCT/US2005046190
申请日：2005-12-20
申请人： AVON PROD INC , JONES BRIAN C , HINES MICHELLE D
发明人： JONES BRIAN C , HINES MICHELLE D
IPC分类号： A61K36/18 , A61Q19/08
CPC分类号： A61Q19/08 , A61K8/63 , A61K8/64 , A61K8/97 , A61K2800/782
摘要： The present invention provides a cosmetic composition having a cosmetically acceptable vehicle and one or more gap junction inhibitors and/or one or more choline acetyl transferase (CAT) inhibitors in an amount effective for reducing the appearance of deep wrinkles on the skin. Also provided is a method of reducing the appearance of deep wrinkles on the skin, including the steps of topically applying to the skin the above cosmetic composition in an amount and for a period of time sufficient to reduce the appearance of deep wrinkles on the skin.
摘要翻译：本发明提供了化妆品组合物，其具有化妆品可接受的载体和一种或多种间隙连接抑制剂和/或一种或多种胆碱乙酰转移酶（CAT）抑制剂，其量可有效减少皮肤上深度皱纹的出现。还提供了一种减少皮肤上深度皱纹出现的方法，包括将上述化妆品组合物以足以减少皮肤上深度皱纹出现的量和时间局部施用于皮肤的步骤。

4. 发明申请

WO2005060536A3 si-RNA-MEDIATED GENE SILENCING TECHNOLOGY TO INHIBIT TYROSINASE AND REDUCE PIGMENTATION 审中-公开
标题翻译： si-RNA介导的基因沉默技术抑制酪氨酸激酶和减少色素沉着
公开(公告)号：WO2005060536A3
公开(公告)日：2007-03-22
申请号：PCT/US2004039941
申请日：2004-11-30
申请人： AVON PROD INC , BINETTI RALPH R , JONES BRIAN C
发明人： BINETTI RALPH R , JONES BRIAN C
IPC分类号： A61K48/00 , C07H21/04 , C12N15/11 , C12N15/113
CPC分类号： C12N15/1137 , C12N15/111 , C12N2310/14 , C12N2320/32 , C12Y114/18001
摘要： The present invention describes compositions and methods for treating, preventing and improving hyperpigmentation, or other unwanted pigmentation of the skin, or other unwanted skin condition, such as age spots, aged skin, skin discoloration, etc., wherein the compositions include siRNA-gene silencing oligomers specific for tyrosinase. The compositions are used to treat a broad variety of pigmentation conditions, and are preferably applied to the skin, or are delivered by directed means to a site in need thereof.
摘要翻译：本发明描述了用于治疗，预防和改善皮肤色素沉着过度或其它不需要的色素沉着或其它不需要的皮肤状况（如老年斑，老化皮肤，皮肤变色等）的组合物和方法，其中组合物包括siRNA-基因沉默酪氨酸酶特异性低聚物。所述组合物用于治疗各种各样的色素沉着状况，并且优选施用于皮肤，或通过定向方式递送至有需要的部位。

5. 发明申请

WO2004094585A3 METHOD AND APPARATUS FOR PRODUCING A TEA BEVERAGE EMPLOYNG A CONTINUOUS MIXING CHAMBER 审中-公开
标题翻译：用于生产连续混合室的茶叶饮料的方法和装置
公开(公告)号：WO2004094585A3
公开(公告)日：2005-06-02
申请号：PCT/US2004008836
申请日：2004-03-23
申请人： JONES BRIAN C , ROTHENBERG PAUL JOHN
发明人： JONES BRIAN C , ROTHENBERG PAUL JOHN
IPC分类号： A47J31/41 , B67D1/00 , B67D7/74 , B67D7/80 , A23F3/00 , A23F5/00 , A23L2/00 , A23L2/38
CPC分类号： B67D1/0021 , A47J31/401 , A47J31/41 , B67D2210/00118
摘要： The present invention relates to a mixing chamber for producing a non-carbonated tea beverage, wherein the tea beverage is susceptible to growth of detrimental microorganisms, comprising: a tea concentrate feed line (135) having a check valve; a hot water feed line (128); a cold water feed line having a check valve (129); and wherein the non-carbonated tea beverage is better than an acceptable microbial count and is a substantially homogeneous non-carbonated tea beverage. The present invention also relates to a method of producing a non-carbonated tea beverage, wherein the tea beverage is susceptible to growth of detrimental microorganisms, comprising the steps of: continuously feeding hot water into a mixing chamber; continuously feeding tea concentrate into the mixing chamber; continuously feeding cold water into the mixing chamber (122); continuously mixing the tea concentrate, hot water and cold water in the mixing chamber; and continuously dispensing a non-carbonated tea beverage wherein the non-carbonated tea beverage is better than an acceptable microbial count and is a substantially homogeneous non-carbonated tea beverage.
摘要翻译：本发明涉及一种用于生产非碳酸茶饮料的混合室，其中所述茶饮料易受到有害微生物的生长，包括：具有止回阀的茶浓缩物供给管线（135）热水供给管线（128）; 具有止回阀（129）的冷水供给管线; 并且其中所述非碳酸化茶饮料优于可接受的微生物计数，并且是基本均匀的非碳酸化茶饮料。本发明还涉及一种生产非碳酸化茶饮料的方法，其中所述茶饮料易受有害微生物生长，包括以下步骤：将热水连续地供入混合室; 将浓缩咖啡连续喂入混合室; 连续地将冷水送入混合室（122）中; 在混合室中连续混合茶精，热水和冷水; 并连续分配非碳酸化茶饮料，其中非碳酸化茶饮料比可接受的微生物数量更好，并且是基本均匀的非碳酸化茶饮料。

6. 发明申请

WO2004060289A3 USE OF PURSLANE TO TREAT FACIAL WRINKLES 审中-公开
标题翻译：用于治疗面部皱纹的使用
公开(公告)号：WO2004060289A3
公开(公告)日：2005-04-28
申请号：PCT/US0340443
申请日：2003-12-17
申请人： AVON PROD INC , JONES BRIAN C
发明人： JONES BRIAN C
IPC分类号： A61K8/02 , A61K8/97 , A61Q19/00 , A61Q19/08 , A61K35/78
CPC分类号： A61K8/97 , A61Q19/08
摘要： The invention relates to topical compositions containing components of plants from the Purslane family and methods for improving the aesthetic appearance of skin, particularly, preventing, ameliorating, treating and/or reducing fine lines and/or wrinkles. More particularly, the present invention relates to the use of topical compositions containing extract from the Portulaca oleracea plant to treat signs of dermatological aging, especially facial lines and deep wrinkles, and/or improve the aesthetic appearance of the skin. Preferably, the composition is applied once daily to the skin.
摘要翻译：本发明涉及含有来自Purslane家族的植物成分的局部组合物以及用于改善皮肤美学外观，特别是预防，改善，治疗和/或减少细纹和/或皱纹的方法。更具体地，本发明涉及含有来自马齿苋属植物的提取物的局部组合物用于治疗皮肤病学老化的征象，特别是面部线条和深层皱纹，和/或改善皮肤美学外观的用途。优选地，将组合物每天一次施用于皮肤。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式