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1. 发明申请

WO2010131865A2 ANTIMICROBIAL COMPOSITION WITH AN ACTIVITY AGAINST AN ANTIBIOTIC-RESISTANT STRAIN 审中-公开
标题翻译：具有抗生素抗性活性的抗微生物组合物
公开(公告)号：WO2010131865A2
公开(公告)日：2010-11-18
申请号：PCT/KR2010002845
申请日：2010-05-04
申请人： UNIV CHUNG ANG IND , KIM JONG-KEE , KIM HUN , LIM SOO-YEON , LEE SOO-SEONG
发明人： KIM JONG-KEE , KIM HUN , LIM SOO-YEON , LEE SOO-SEONG
IPC分类号： A61K31/26 , A61P31/00 , A61P31/04
CPC分类号： A61K31/26
摘要： The present invention relates to an antimicrobial composition against an antibiotic-resistant strain containing, as active ingredients, one or more elements selected from a group consisting of sulforaphene and sulforaphane. More particularly, the present invention relates to an antimicrobial composition which contains, as active ingredients, one or more elements selected from a group consisting of sulforaphene and sulforaphane, and which acts on methicillin-resistant staphylococcus, vancomycin-resistant enterococcus or antibiotic-resistant colon bacillus, pneumobacillus, salmonella typhimurium and enterococcus faecalis and the like to inhibit the growth of an antibiotic-resistant strain. The antimicrobial composition of the present invention inhibits the growth of gram-negative bacillus and gram-positive bacillus having a resistance to beta-lactam antibiotics such as vancomycin, penicillin, methicillin and the like or against non-beta-lactam antibiotics, and therefore can be used in the prevention and treatment of various infectious diseases caused by antibiotic-resistant bacterial infections, and can be valuably used as antibiotics against super-bacteria.
摘要翻译：本发明涉及一种抗生素抗性菌株的抗微生物组合物，其含有选自由磺基吡咯和萝卜硫素组成的组中的一种或多种元素作为活性成分。更具体地说，本发明涉及一种抗微生物组合物，其含有作为活性成分的一种或多种选自由磺基芴和萝卜硫素组成的组分，并且其作用于耐甲氧西林葡萄球菌，万古霉素耐药性肠球菌或抗生素耐药结肠杆菌，肺炎杆菌，鼠伤寒沙门氏菌和粪肠球菌等，以抑制抗生素抗性菌株的生长。本发明的抗微生物组合物抑制对β-内酰胺抗生素如万古霉素，青霉素，甲氧西林等具有抗性或针对非β-内酰胺抗生素的革兰氏阴性杆菌和革兰氏阳性杆菌的生长，因此可以用于预防和治疗由抗生素抵抗细菌感染引起的各种感染性疾病，可以有价值地用作抗细菌的抗生素。

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