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1. 发明申请

WO2007117826A2 IMPLANTABLE MEDICAL DEVICE SYSTEM AND METHOD WITH SIGNAL QUALITY MONITORING AND RESPONSE 审中-公开
标题翻译：可植入医疗器械系统及信号质量监测与响应方法
公开(公告)号：WO2007117826A2
公开(公告)日：2007-10-18
申请号：PCT/US2007/063795
申请日：2007-03-12
申请人： MEDTRONIC, INC. , GREENHUT, Saul E. , VITENSE, Haooly S. , STADLER, Robert W.
发明人： GREENHUT, Saul E. , VITENSE, Haooly S. , STADLER, Robert W.
IPC分类号： A61N1/37 , A61B5/0428 , A61N1/05
CPC分类号： A61N1/3704 , A61B5/042 , A61B5/0452 , A61B5/7203 , A61B5/7221 , A61B5/726 , A61N1/05
摘要： An implantable medical device system and method are provided for monitoring the quality of signals sensed by a subcutaneously implanted device using subcutaneous electrodes. In one embodiment, the method includes selecting one or more sensing vectors; sensing signals from selected sensing vectors, determining a signal quality metric in response to a sensed signal, comparing the signal quality metric to a predetermined threshold, and generating a loss of signal quality response in response to the signal quality crossing the threshold.
摘要翻译：提供了一种植入式医疗装置系统和方法，用于监测由皮下植入装置使用皮下电极感测的信号的质量。在一个实施例中，该方法包括选择一个或多个感测向量; 感测来自所选择的感测向量的信号，响应于感测到的信号确定信号质量度量，将信号质量度量与预定阈值进行比较，以及响应于穿过阈值的信号质量而产生信号质量响应的损失。

2. 发明申请

WO2007117822A1 METHOD AND APPARATUS FOR DETECTING ARRHYTHMIAS IN A SUBCUTANEOUS MEDICAL DEVICE 审中-公开
标题翻译：用于检测亚急性医疗器械中的ARRHYTHMIAS的方法和装置
公开(公告)号：WO2007117822A1
公开(公告)日：2007-10-18
申请号：PCT/US2007/063784
申请日：2007-03-12
申请人： MEDTRONIC, INC. , STADLER, Robert W. , GHANEM, Raja N. , ZHANG, Xusheng , GREENHUT, Saul E.
发明人： STADLER, Robert W. , GHANEM, Raja N. , ZHANG, Xusheng , GREENHUT, Saul E.
IPC分类号： A61B5/046 , A61B5/0464 , A61N1/39
CPC分类号： A61N1/3956 , A61B5/046 , A61B5/0464 , A61B5/7239 , A61N1/3621
摘要： A method and apparatus for detecting a cardiac event in a medical device that includes sensing cardiac signals from a plurality of electrodes forming a first sensing vector and a second sensing vector, advancing from a first state to a second state in response to processing of an interval associated with a cardiac cycle of the sensed cardiac signals, and advancing from the second state in response to processing of a cardiac signal sensed during a predetermined sensing window.
摘要翻译：一种用于检测医疗装置中的心脏事件的方法和装置，包括：感测来自形成第一感测向量的多个电极的心脏信号和响应于间隔的处理从第一状态进入第二状态的第二感测向量与感测的心脏信号的心动周期相关联，并且响应于在预定感测窗口期间感测的心脏信号的处理而从第二状态前进。

3. 发明申请

WO2010033400A1 FILTERING OF A PHYSIOLOGIC SIGNAL IN A MEDICAL DEVICE 审中-公开
标题翻译：医疗设备中生理信号的过滤
公开(公告)号：WO2010033400A1
公开(公告)日：2010-03-25
申请号：PCT/US2009/056184
申请日：2009-09-08
申请人： MEDTRONIC, INC. , CHO, Yong K. , BENNETT, Tommy D. , ERICKSON, Mark K. , SHRIVASTAV, Maneesh , KLECKNER, Karin J. , SPERLING, Charles P. , COREY, Robert A. , GREENHUT, Saul E.
发明人： CHO, Yong K. , BENNETT, Tommy D. , ERICKSON, Mark K. , SHRIVASTAV, Maneesh , KLECKNER, Karin J. , SPERLING, Charles P. , COREY, Robert A. , GREENHUT, Saul E.
IPC分类号： A61B5/08 , A61B5/0205 , A61B5/03 , H03H21/00 , A61N1/365 , A61N1/37 , A61N1/372
CPC分类号： A61B5/6846 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/0816 , A61B5/4818 , A61N1/36514 , A61N1/3702 , A61N1/37258
摘要： A system and method for filtering a pressure signal in a medical device in which a sensor terminal senses the pressure signal, an electrode terminal receives cardiac electrical signals, a signal filtering system filters the sensed pressure signal in response to a determined heart rate to generate a heart-rate dependent frequency response, and a microprocessor derives a respiration signal in response to the heart rate dependent frequency response, and determines metrics of hemodynamic function in response to the derived respiration signal.
摘要翻译：一种用于过滤医疗装置中的压力信号的系统和方法，其中传感器端子感测压力信号，电极端子接收心脏电信号，信号滤波系统响应于确定的心率来过滤感测到的压力信号，以产生心率依赖频率响应，并且微处理器响应于心率依赖的频率响应导出呼吸信号，并且响应于所得到的呼吸信号确定血液动力学函数的度量。

4. 发明申请

WO2012148513A1 MEASUREMENT OF CARDIAC CYCLE LENGTH AND PRESSURE METRICS FROM PULMONARY ARTERIAL PRESSURE 审中-公开
标题翻译：心脏循环长度和压力测量从脉搏压力测量
公开(公告)号：WO2012148513A1
公开(公告)日：2012-11-01
申请号：PCT/US2012/022154
申请日：2012-01-23
申请人： MEDTRONIC, INC. , GREENHUT, Saul E.
发明人： GREENHUT, Saul E.
IPC分类号： A61B5/021 , A61B5/0215
CPC分类号： A61B5/0215 , A61B5/02108 , A61B5/4839 , A61B5/6869 , A61B5/7239 , A61B5/7246 , A61M5/1723 , A61N1/08 , A61N1/36564
摘要： A method and apparatus for monitoring a cardiovascular pressure signal in a medical device that includes determining whether the sensed pressure signal is greater than a first pressure threshold, determining a first metric of the pressure signal in response to the sensed pressure signal being greater than the first pressure threshold, determining whether the sensed pressure signal is greater than a second pressure threshold not equal to the first pressure threshold, determining a second metric of the pressure signal in response to the sensed pressure signal being greater than the first pressure threshold, and determining at least one of a systolic pressure or a diastolic pressure, wherein the at least one of a systolic pressure or a diastolic pressure is determined based on the first metric in response to the pressure signal not being greater than the second threshold, and based on the second metric in response to the pressure signal being greater than the second threshold.
摘要翻译：一种用于监测医疗装置中的心血管压力信号的方法和装置，包括确定感测到的压力信号是否大于第一压力阈值，响应于感测到的压力信号确定压力信号的第一度量大于第一压力信号压力阈值，确定所感测到的压力信号是否大于不等于第一压力阈值的第二压力阈值，响应于所感测的压力信号确定压力信号的第二度量大于第一压力阈值，并且在收缩压或舒张压中的至少一个，其中基于所述第一度量响应于所述压力信号不大于所述第二阈值来确定所述收缩压或舒张压中的至少一个，并且基于所述第二阈值响应于压力信号大于第二阈值的度量。

5. 发明申请

WO2010033405A1 METHOD AND APPARATUS FOR DETECTING RESPIRATORY EFFORT IN A MEDICAL DEVICE 审中-公开
标题翻译：用于检测医疗装置中呼吸道作用的方法和装置
公开(公告)号：WO2010033405A1
公开(公告)日：2010-03-25
申请号：PCT/US2009/056305
申请日：2009-09-09
申请人： MEDTRONIC, INC. , CHO, Yong K. , BENNETT, Tommy D. , ERICKSON, Mark K. , SHRIVASTAV, Maneesh , GREENHUT, Saul E. , KLECKNER, Karin J. , SPERLING, Charles P. , COREY, Robert A.
发明人： CHO, Yong K. , BENNETT, Tommy D. , ERICKSON, Mark K. , SHRIVASTAV, Maneesh , GREENHUT, Saul E. , KLECKNER, Karin J. , SPERLING, Charles P. , COREY, Robert A.
IPC分类号： A61B5/08 , A61B5/0205 , A61B5/03 , A61N1/365 , A61N1/37 , A61N1/372 , H03H21/00
CPC分类号： A61B5/6846 , A61B5/0031 , A61B5/0205 , A61B5/0215 , A61B5/0816 , A61B5/4818 , A61N1/36514 , A61N1/3702 , A61N1/37258
摘要： A medical device for determining a respiratory effort having a pressure sensor to sense pressure signals, a housing having system components positioned therein, and a microprocessor positioned within the housing, wherein the microprocessor detects an inspiration and an expiration in response to the pressure signals, detects a breath in response to the detected inspiration and the detected expiration, and determines the respiratory effort in response to the detected breath.
摘要翻译：一种用于确定具有用于感测压力信号的压力传感器的呼吸力的医疗装置，具有定位在其中的系统部件的壳体和位于壳体内的微处理器，其中微处理器响应于压力信号检测吸气和呼气，检测响应于检测到的吸气和检测到的呼气而呼吸，并且响应于检测到的呼吸来确定呼吸努力。

6. 发明申请

WO2022046394A1 MEDICAL DEVICE AND METHOD FOR ENABLING A CARDIAC MONITORING FEATURE 审中-公开
公开(公告)号：WO2022046394A1
公开(公告)日：2022-03-03
申请号：PCT/US2021/045154
申请日：2021-08-09
申请人： MEDTRONIC, INC.
发明人： GALARNEAU, Michelle M. , GREENHUT, Saul E. , GRINBERG, Yanina , SHELDON, Todd J.
IPC分类号： A61N1/365 , A61N1/372 , A61N1/375 , A61B5/00 , A61N1/37
摘要： A medical device is configured to sense a cardiac signal, determine a monitoring metric representative of activity of at least one heart chamber from the sensed cardiac signal, and determine that the monitoring metric meets expected rhythm criteria. The medical device may enable a monitoring feature of the medical device that is based on processing and analysis of the cardiac signal in response to the monitoring metric meeting the expected rhythm criteria.

7. 发明申请

WO2017189802A1 MULTI-THRESHOLD SENSING OF CARDIAC ELECTRICAL SIGNALS IN AN EXTRACARDIOVASCULAR IMPLANTABLE CARDIOVERTER DEFIBRILLATOR 审中-公开
标题翻译：心脏外科植入式心脏起搏器除颤器心脏电信号的多次阈值检测
公开(公告)号：WO2017189802A1
公开(公告)日：2017-11-02
申请号：PCT/US2017/029762
申请日：2017-04-27
申请人： MEDTRONIC, INC.
发明人： CAO, Jian , EBELING, Timothy A. , GREENHUT, Saul E. , HEINKS, Michael W. , SANCHEZ, Irving J. , SOLHEIM, Paul R. , ZHANG, Xusheng , ARNE, Gerald P.
IPC分类号： A61B5/0456 , A61N1/05 , A61N1/362 , A61N1/365 , A61N1/39
摘要： An implantable medical device system capable of sensing cardiac electrical signals includes a sensing circuit, a therapy delivery circuit and a control circuit. The sensing circuit is configured to receive a cardiac electrical signal and sense a cardiac event in response to the signal crossing a cardiac event sensing threshold. The therapy delivery circuit is configured to deliver an electrical stimulation therapy to a patient's heart via the electrodes coupled to the implantable medical device. The control circuit is configured to control the sensing circuit to set a starting value of the cardiac event sensing threshold and hold the starting value constant for a sense delay interval. The control circuit is further configured to detect an arrhythmia based on cardiac events sensed by the sensing circuit and control the therapy delivery circuit to deliver the electrical stimulation therapy in response to detecting the arrhythmia.
摘要翻译：能够感测心电信号的可植入医疗设备系统包括感测电路，治疗传递电路和控制电路。感测电路被配置为接收心脏电信号并且响应于信号越过心脏事件感测阈值来感测心脏事件。治疗递送电路被配置为经由耦合到可植入医疗设备的电极将电刺激治疗递送到患者的心脏。控制电路被配置为控制感测电路设置心脏事件感测阈值的起始值并且将感测延迟间隔中的起始值保持恒定。控制电路还被配置为基于由感测电路感测的心脏事件来检测心律失常，并且响应于检测到心律失常而控制治疗传递电路传递电刺激治疗。

8. 发明申请

WO2016144575A1 MULTI-CHAMBER INTRACARDIAC PACING SYSTEM 审中-公开
标题翻译：多室内吸入系统
公开(公告)号：WO2016144575A1
公开(公告)日：2016-09-15
申请号：PCT/US2016/019889
申请日：2016-02-26
申请人： MEDTRONIC, INC.
发明人： DEMMER, Wade M. , SHELDON, Todd J. , GREENHUT, Saul E. , REINKE, James D.
IPC分类号： A61N1/375 , A61N1/368 , A61N1/372 , A61N1/362 , A61B5/00 , A61B5/0452
CPC分类号： A61N1/3756 , A61B5/0452 , A61B5/4836 , A61B5/686 , A61N1/3622 , A61N1/3682 , A61N1/3688 , A61N1/37205
摘要： The control module of a first pacemaker included in an implantable medical device system including the first pacemaker and a second pacemaker is configured to set a pacing escape interval in response to a far field pacing pulse sensed by the first pacemaker. The far field pacing pulse is a pacing pulse delivered by the second pacemaker. The pacing escape interval is allowed to continue without restarting the in response to a far field intrinsic event sensed by the first pacemaker during the pacing escape interval. The first pacemaker delivers a cardiac pacing pulse to the heart upon expiration of the pacing escape interval.
摘要翻译：包括在包括第一起搏器和第二起搏器的可植入医疗装置系统中的第一起搏器的控制模块被配置为响应于由第一起搏器感测到的远场起搏脉冲设置起搏逃生间隔。远场起搏脉冲是由第二起搏器提供的起搏脉冲。在起搏逃逸间隔期间允许响应于由第一起搏器感测到的远场固有事件而不重新启动起搏逃生间隔。第一个起搏器在起搏逃生间隔期满后向心脏提供心脏起搏脉冲。

9. 发明申请

WO2016064644A1 FILTERING NOISE FROM A SIGNAL SUBJECTED TO BLANKING 审中-公开
标题翻译：从被遮挡的信号中过滤噪声
公开(公告)号：WO2016064644A1
公开(公告)日：2016-04-28
申请号：PCT/US2015/055622
申请日：2015-10-15
申请人： MEDTRONIC, INC.
发明人： HEMMING, Michael T. , GREENHUT, Saul E.
IPC分类号： A61N1/365 , A61N1/37 , A61B5/0428
CPC分类号： A61B5/7203 , A61B5/04012 , A61B5/0402 , A61B5/0452 , A61B5/0538 , A61B5/1107 , A61B5/686 , A61N1/365 , A61N1/3718
摘要： The disclosure describes techniques and systems for filtering noise from a physiological signal. In one example, one or more processors are configured to receive a signal indicative of physiological activity of a patient, wherein the signal comprises noise at one or more frequencies, and filter the noise from the signal according to a noise rejection model, wherein the noise rejection model predicts the noise at the one or more frequencies. The one or more processors may also be configured to, responsive to initiation of a blanking period for the signal, advance the noise rejection model in time during the blanking period, and, responsive to termination of the blanking period, filter, based on the noise rejection model advanced in time, the noise at the one or more frequencies from the signal.
摘要翻译：本公开描述了用于从生理信号滤波噪声的技术和系统。在一个示例中，一个或多个处理器被配置为接收指示患者的生理活动的信号，其中所述信号包括一个或多个频率的噪声，并且根据噪声抑制模型对来自信号的噪声进行滤波，其中噪声拒绝模型预测在一个或多个频率的噪声。一个或多个处理器还可以被配置为响应于信号的消隐周期的启动，在消隐期间及时推进噪声抑制模型，并且响应消隐周期的终止，基于噪声进行滤波拒绝模式及时提前，噪声在一个或多个频率的信号。

10. 发明申请

WO2016014330A1 SYSTEM AND METHOD FOR TRIGGERED PACING 审中-公开
标题翻译：触发的系统和方法
公开(公告)号：WO2016014330A1
公开(公告)日：2016-01-28
申请号：PCT/US2015/040713
申请日：2015-07-16
申请人： MEDTRONIC, INC.
发明人： GREENHUT, Saul E. , CARNEY, James K.
IPC分类号： A61N1/372 , A61N1/375 , A61N1/362
CPC分类号： A61N1/365 , A61N1/3621 , A61N1/3622 , A61N1/37205 , A61N1/37211 , A61N1/37288 , A61N1/3756
摘要： A medical device system including an intracardiac pacemaker is configured to receive by an implantable medical device sensing module a first cardiac signal using a first pair of electrodes implanted outside the cardiovascular system and identify a P-wave from the first cardiac signal. The system transmits a wireless trigger signal to the intracardiac pacemaker in response to identifying the P-wave. The intracardiac pacemaker delivers a pacing therapy in response to the trigger signal.
摘要翻译：包括心内心脏起搏器的医疗装置系统被配置为使用植入在心血管系统外部的第一对电极并且从第一心脏信号识别P波，由可植入医疗装置感测模块接收第一心脏信号。响应于识别P波，系统向心脏起搏器发送无线触发信号。心脏起搏器响应于触发信号提供起搏治疗。

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