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1. 发明申请

WO0118021A9 B7-LIKE POLYNUCLEOTIDES, POLYPEPTIDES, AND ANTIBODIES 审中-公开
标题翻译： B7样多核苷酸，多肽和抗体
公开(公告)号：WO0118021A9
公开(公告)日：2002-11-28
申请号：PCT/US0023792
申请日：2000-08-30
申请人： HUMAN GENOME SCIENCES INC , RUBEN STEVEN M , CHEN LIEPING , MAYO FOUNDATION , BAKER KEVIN , NI JIAN
发明人： RUBEN STEVEN M , CHEN LIEPING , BAKER KEVIN , NI JIAN
IPC分类号： G01N33/50 , A61K31/7115 , A61K31/712 , A61K31/7125 , A61K31/713 , A61K35/76 , A61K38/00 , A61K48/00 , A61P1/00 , A61P1/02 , A61P1/04 , A61P1/16 , A61P1/18 , A61P3/10 , A61P5/00 , A61P5/14 , A61P7/00 , A61P7/02 , A61P7/04 , A61P7/06 , A61P7/08 , A61P9/00 , A61P9/04 , A61P9/06 , A61P9/08 , A61P9/10 , A61P9/14 , A61P11/00 , A61P11/06 , A61P13/02 , A61P13/12 , A61P15/08 , A61P15/18 , A61P17/00 , A61P17/02 , A61P17/04 , A61P17/06 , A61P19/02 , A61P19/04 , A61P19/06 , A61P19/08 , A61P19/10 , A61P21/00 , A61P21/02 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/28 , A61P27/02 , A61P27/06 , A61P27/14 , A61P27/16 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/08 , A61P43/00 , C07K14/47 , C07K14/705 , C07K14/725 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04 , C07K14/46 , C07K14/52 , C12N15/00 , C12N15/63
CPC分类号： C07K14/70532 , A61K38/00
摘要： The present invention relates to novel human B7-like polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human B7-like polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human B7-like polypeptides.
摘要翻译：本发明涉及新的人B7样多肽和含有编码这些多肽的基因的编码区的分离的核酸。还提供了用于生产人类B7样多肽的载体，宿主细胞，抗体和重组方法。本发明进一步涉及用于诊断和治疗与这些新型人类B7样多肽有关的病症的诊断和治疗方法。

2. 发明申请

WO2007020484A3 INTERLOCKING COMPONENT ASSEMBLY SYSTEM 审中-公开
标题翻译：互锁组件组装系统
公开(公告)号：WO2007020484A3
公开(公告)日：2007-04-19
申请号：PCT/IB2004004476
申请日：2004-07-27
申请人： THAI UNIVERSAL OFFICE PRODUCTS , BAKER KEVIN
发明人： BAKER KEVIN
IPC分类号： F16B12/38 , A47B47/02 , A47B47/05 , A47B67/04 , F16B12/02
CPC分类号： F16B12/38 , A47B47/0075 , A47B47/02 , A47B47/05
摘要： An interlocking component assembly is made of a plurality of frame components and a plurality of panels. One panel is formed integrally with a respective frame to form a frame and panel component. A channel formed along the entire periphery of each of the frame components enables each of the frame and panel components to be interconnected. During assembly the channel of one frame component is inserted within a channel of another frame component to lock the components together along the length thereof. A plurality of locking tabs are disposed within the channel of each of the plurality of frame components. A plurality of apertures are also disposed within the channel of each of the plurality of frame components, wherein when the channel of a frame component is inserted within the channel of another frame component at least one locking tab is received within a corresponding aperture. This process is repeated until a three-dimensional unit is formed.
摘要翻译：互锁部件组件由多个框架部件和多个面板构成。一个面板与相应的框架一体地形成以形成框架和面板部件。沿着每个框架部件的整个周边形成的通道使得框架和面板部件中的每一个能够相互连接。在组装期间，一个框架部件的通道被插入另一个框架部件的通道中，以沿着其长度将部件锁定在一起。多个锁定突出部设置在多个框架部件的每个的通道内。多个孔也设置在多个框架部件的每一个的通道内，其中当框架部件的通道插入到另一个框架部件的通道内时，至少一个锁定突片被接收在相应的孔内。重复该过程直到形成三维单元。

3. 发明申请

WO0107611A3 Novel polynucleotides and method for the use of thereof 审中-公开
标题翻译：新型多核苷酸及其使用方法
公开(公告)号：WO0107611A3
公开(公告)日：2001-08-23
申请号：PCT/US0020006
申请日：2000-07-21
申请人： BAKER KEVIN , GODDARD AUDREY , WOOD WILLIAM
发明人： BAKER KEVIN , GODDARD AUDREY , WOOD WILLIAM
IPC分类号： C12N15/09 , A61K31/7088 , A61K38/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/12 , C12P21/08 , C12Q1/68 , G01N33/68
CPC分类号： C07K14/47
摘要： The present invention is directed to novel polynucleotides and to polypeptides encoded thereby. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译：本发明涉及新型多核苷酸及其编码的多肽。本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法发明。

4. 发明申请

WO9963088A8 SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME 审中-公开
标题翻译：分泌和转运蛋白多核苷酸和编码其的核酸
公开(公告)号：WO9963088A8
公开(公告)日：2000-10-19
申请号：PCT/US9912252
申请日：1999-06-02
申请人： GENENTECH INC , BAKER KEVIN , CHEN JIAN , GODDARD AUDREY , GURNEY AUSTIN L , SMITH VICTORIA , WATANABE COLIN K , WOOD WILLIAM I , YUAN JEAN
发明人： BAKER KEVIN , CHEN JIAN , GODDARD AUDREY , GURNEY AUSTIN L , SMITH VICTORIA , WATANABE COLIN K , WOOD WILLIAM I , YUAN JEAN
IPC分类号： C07K14/705 , C12N15/12 , C07K16/28 , C12N15/62
CPC分类号： C07K14/705 , C07K2319/00
摘要： The present invention is directed to polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译：本发明涉及多肽和编码那些多肽的核酸分子。本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法发明。

5. 发明申请

WO9963088A3 MEMBRANE-BOUND PROTEINS AND NUCLEIC ACIDS ENCODING THE SAME 审中-公开
标题翻译：膜结合蛋白和核酸编码它们
公开(公告)号：WO9963088A3
公开(公告)日：2001-03-29
申请号：PCT/US9912252
申请日：1999-06-02
申请人： GENENTECH INC , BAKER KEVIN , CHEN JIAN , GODDARD AUDREY , GURNEY AUSTIN L , SMITH VICTORIA , WATANABE COLIN K , WOOD WILLIAM I , YUAN JEAN
发明人： BAKER KEVIN , CHEN JIAN , GODDARD AUDREY , GURNEY AUSTIN L , SMITH VICTORIA , WATANABE COLIN K , WOOD WILLIAM I , YUAN JEAN
IPC分类号： C07K14/705 , C12N15/12 , C07K16/28 , C12N15/62
CPC分类号： C07K14/705 , C07K2319/00
摘要： The present invention is directed to membrane-bound polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译：本发明涉及膜结合多肽和编码那些多肽的核酸分子。本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法发明。

6. 发明申请

WO0012708A3 FURTHER PRO POLYPEPTIDES AND SEQUENCES THEREOF 审中-公开
标题翻译：其他多肽及其序列
公开(公告)号：WO0012708A3
公开(公告)日：2001-10-04
申请号：PCT/US9920111
申请日：1999-09-01
申请人： GENENTECH INC , BAKER KEVIN , GODDARD AUDREY , GURNEY AUSTIN L , SMITH VICTORIA , WATANABE COLIN K , WOOD WILLIAM I
发明人： BAKER KEVIN , GODDARD AUDREY , GURNEY AUSTIN L , SMITH VICTORIA , WATANABE COLIN K , WOOD WILLIAM I
IPC分类号： C07K14/705 , C12N15/12 , C07K16/28 , C12N5/10 , C12N15/62 , C12Q1/68
CPC分类号： C07K14/705 , C07K2319/00
摘要： Membrane-bound proteins and receptor molecules have various industrial applications, including as pharmaceutical and diagnostic agents. Receptor immunoadhesins, for instance, can be employed as therapeutic agents to block receptor-ligand interactions. The membrane-bound proteins can also be employed for screening of potential peptide or small molecule inhibitors of the relevant receptor/ligand interaction. Efforts are being undertaken by both industry and academia to identify new, native receptor or membrane-bound proteins. Many efforts are focused on the screening of mammalian recombinant DNA libraries to identifiy the coding sequences for novel receptor or membrane-bound proteins. The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
摘要翻译：膜结合蛋白和受体分子具有各种工业应用，包括作为药物和诊断剂。例如，受体免疫粘附素可以用作阻断受体 - 配体相互作用的治疗剂。膜结合蛋白也可用于筛选相关受体/配体相互作用的潜在肽或小分子抑制剂。工业界和学术界正在努力确定新的天然受体或膜结合蛋白。许多努力集中在筛选哺乳动物重组DNA文库以鉴定新受体或膜结合蛋白的编码序列。本发明涉及新型多肽和编码那些多肽的核酸分子。本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法发明。

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