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1. 发明申请

WO2021195582A1 METHODS OF ALLEVIATING SYMPTOMS OF OCULAR SURFACE DISCOMFORT USING MEDICAL ICE SLURRY 审中-公开
公开(公告)号：WO2021195582A1
公开(公告)日：2021-09-30
申请号：PCT/US2021/024514
申请日：2021-03-26
申请人： STEFATER, James Anthony, III , STRYJEWSKI, Tomas Pawel , SABIR, Sameer
发明人： STEFATER, James Anthony, III , STRYJEWSKI, Tomas Pawel , SABIR, Sameer
IPC分类号： A61K47/10 , A61K9/10 , A61B18/02 , A61F7/02 , A61M5/31 , A61M5/44
摘要： Disclosed herein is a method of alleviating symptoms of ocular surface discomfort, the method comprising: topically applying a cold slurry adjacent to a corneal limbus of an eye of a patient, wherein the cold slurry comprises water and a freezing point depressant, wherein the topical application of the cold slurry is configured to cause a degree of numbing of a cornea of the eye for a period of time, and wherein an ocular sensation of the eye is restored following the period of time.

2. 发明申请

WO2015166475A1 SOIL SCREENING APPARATUS AND A METHOD FOR SCREENING SOIL 审中-公开
标题翻译：土壤筛选装置和筛选土壤的方法
公开(公告)号：WO2015166475A1
公开(公告)日：2015-11-05
申请号：PCT/IE2015/000004
申请日：2015-04-30
申请人： DOYLE, Larry Thomas , DELAHUNTY, James Anthony
发明人： DOYLE, Larry Thomas , DELAHUNTY, James Anthony
IPC分类号： B07B1/00 , B07B1/04 , B07B1/15 , B07B13/16
CPC分类号： B07B1/005 , B07B1/04 , B07B1/15 , B07B13/16 , B07B2201/04
摘要： Apparatus (1) for screening soil comprises a chassis (2) having an upwardly inclined conveyor (10) mounted therein. A forward soil engaging scraper plate (8) is coupled to and extends forwardly from an upstream end (11) of the conveyor (10) for engaging the soil beneath the surface for scraping the soil above the scraper plate (8) and transferring the scraped soil onto the conveyor (10) as the apparatus (1) is urged forwardly. The soil is conveyed to a downstream end (12) of the conveyor (10) and delivered to a first screen (30) which screens material of a first predefined size of 150mm and greater from the material and discharges the screened material into a storage container (32). Material of size less than the first predefined size passes through the first screen (30) to a second screen (35) which retains material of a second predefined size of 20mm and greater and passes material of less than the second predefined size of 20mm, for example, soil fines therethrough, which are deposited on the ground. The second screen (35) is configured to urge the material of the second predefined size of 20mm and greater towards a forward downstream end (37) of the second screen (35) which is deposited onto the ground in advance of the soil fines, so that the fines are deposited on the ground on top of the material of the second predefined size of 20mm and greater.
摘要翻译：用于筛选土壤的装置（1）包括具有安装在其中的向上倾斜的输送机（10）的底盘（2）。前部土壤接合刮板（8）从输送机（10）的上游端（11）联接并向前延伸，用于接合表面下方的土壤，以刮擦刮板（8）上方的土壤并将刮土当装置（1）被向前推动时，输送机（10）上的土壤。将土壤输送到输送机（10）的下游端（12）并且被输送到第一筛网（30），该筛网从第一筛网材料筛选出第一预定尺寸为150mm以上的材料，并将筛选的材料排放到储存容器（32）。尺寸小于第一预定义尺寸的材料通过第一屏幕（30）到第二屏幕（35），第二屏幕（35）保留第二预定尺寸为20mm及更大的材料，并通过小于20mm的第二预定尺寸的材料，以便例如，通过其中的土壤细粉沉积在地面上。第二屏幕（35）被构造成朝着第二屏幕（35）的向前下游端（37）推动第二预定尺寸为20mm及更大的材料，该第二屏幕（35）在土壤细粉之前沉积到地面上，因此在第二预定尺寸为20mm及以上的材料的顶部将细粉沉积在地面上。

3. 发明申请

WO2013074180A1 COATING METHODS AND COATED ARTICLES 审中-公开
标题翻译：涂料方法和涂料文章
公开(公告)号：WO2013074180A1
公开(公告)日：2013-05-23
申请号：PCT/US2012/052964
申请日：2012-08-30
申请人： GENERAL ELECTRIC COMPANY , AJDELSZTAJN, Leonardo , RUUD, James, Anthony , GRAY, Dennis, Michael
发明人： AJDELSZTAJN, Leonardo , RUUD, James, Anthony , GRAY, Dennis, Michael
IPC分类号： C23C4/12 , C23C4/04 , F16K3/00
CPC分类号： C09D1/00 , C23C4/129 , C23C24/04 , F16K3/30 , Y10T428/252
摘要： One aspect of the present invention includes a method. The method includes combusting a fuel and an oxidant in a combustion chamber of a thermal spray gun to form a combustion stream. The method further includes injecting a liquid and a feedstock material into the combustion stream in the combustion chamber to form an entrained feedstock stream, wherein the feedstock material includes a plurality of cermet particles having a median particle size of less than about 5 microns. The method further includes directing the entrained feedstock stream on a surface of a substrate to form a coating, wherein a temperature of the plurality of cermet particles in the entrained feedstock stream is less than a melting temperature of the plurality of cermet particles. Coated articles are also presented.
摘要翻译：本发明的一个方面包括一种方法。该方法包括在热喷枪的燃烧室中燃烧燃料和氧化剂以形成燃烧流。该方法还包括将液体和原料材料注入燃烧室中的燃烧流中以形成夹带的原料流，其中原料包括多个中值粒度小于约5微米的金属陶瓷颗粒。该方法还包括将夹带的原料流引导到基材的表面上以形成涂层，其中夹带的原料流中的多个金属陶瓷颗粒的温度小于多个金属陶瓷颗粒的熔融温度。还提供涂层制品。

4. 发明申请

WO2013016172A1 SYSTEM AND METHOD OF PROVIDING INFORMATION BASED ON STREET ADDRESS 审中-公开
标题翻译：基于街道地址提供信息的系统和方法
公开(公告)号：WO2013016172A1
公开(公告)日：2013-01-31
申请号：PCT/US2012/047555
申请日：2012-07-20
申请人： GOOGLE INC. , TANG, Xinyu , CHAPIN, Charles , STOUT, Bryce , BREWINGTON, Brian, Edmond , GUGGEMOS, James, Anthony , LIMBER, Mark , YANG, Po-Feng, Paul , MUDURE, Mihai , HAWKINS, Dale
发明人： TANG, Xinyu , CHAPIN, Charles , STOUT, Bryce , BREWINGTON, Brian, Edmond , GUGGEMOS, James, Anthony , LIMBER, Mark , YANG, Po-Feng, Paul , MUDURE, Mihai , HAWKINS, Dale
IPC分类号： G06F17/30 , G06F3/14 , G06Q30/02
CPC分类号： G06F17/3087 , G06Q30/02
摘要： A system and method is provided that, in at least one aspect, associates a search term with a building (1906) that occupies more than one street address (1902) by selecting the term based on all of the listings located at all of the street addresses occupied by the building (1904, 1905).
摘要翻译：提供了一种系统和方法，在至少一个方面，通过基于位于所有街道的所有列表来选择所述术语，将搜索项与占用多于一个街道地址（1902）的建筑物（1906）相关联建筑物占用的地址（1904年，1905年）。

5. 发明申请

WO2012088026A1 AUGMENTATION OF PLACE RANKING USING 3D MODEL ACTIVITY IN AN AREA 审中-公开
标题翻译：在区域中使用3D模型活动的地理位置补充
公开(公告)号：WO2012088026A1
公开(公告)日：2012-06-28
申请号：PCT/US2011/066009
申请日：2011-12-20
申请人： GOOGLE INC. , BREWINGTON, Brian, Edmond , BROWN, Brian, Gammon , GUGGEMOS, James, Anthony , HAWKINS, Dale , STOUT, Bryce
发明人： BREWINGTON, Brian, Edmond , BROWN, Brian, Gammon , GUGGEMOS, James, Anthony , HAWKINS, Dale , STOUT, Bryce
IPC分类号： G06F17/30 , G06F17/40 , G06T19/00
CPC分类号： G06F17/30241 , G06F17/3087
摘要： Aspects of the invention relate generally to ranking geographic locations based on perceived user interest. More specifically, a database (136) of three-dimensional models of buildings or other architectural features may be used to determine the level of user interest in a particular location and accordingly rank, for example, geographic locations or web or map search results with local intent. For example, various signals such as the number of models created by users for a particular location (306), the number of clicks or requests for the models of the particular location (710, 806), the number of POIs contained within or associated with the models associated with the particular geographic location (904), number of categories associated with a model associated with the geographic location (1008), number of embedded views or views of the models associated with the particular location on other web sites (1104), and the age of the models associated with the particular geographic location (1206) may be used.
摘要翻译：本发明的方面一般涉及基于感兴趣的用户兴趣对地理位置进行排名。更具体地，可以使用建筑物或其他建筑特征的三维模型的数据库（136）来确定特定位置处的用户兴趣的水平，并且因此将例如地理位置或具有本地的地理位置或地图搜索结果意图。例如，诸如由特定位置（306）的用户创建的模型的数量，特定位置的模型的点击次数或请求的各种信号（710,806），包含在或与其相关联的POI的数量与特定地理位置相关联的模型（904），与与地理位置相关联的模型（1008）相关联的类别数量，与其他网站（1104）上的特定位置相关联的模型的嵌入视图或视图数量，并且可以使用与特定地理位置相关联的模型的时代（1206）。

6. 发明申请

WO2010123692A1 OPTOELECTRONIC DEVICES AND ORGANIC COMPOUNDS USED THEREIN 审中-公开
标题翻译：光电器件及其使用的有机化合物
公开(公告)号：WO2010123692A1
公开(公告)日：2010-10-28
申请号：PCT/US2010/030390
申请日：2010-04-08
申请人： GENERAL ELECTRIC COMPANY , KONICA MINOLTA HOLDINGS, INC. , YE, Qing , LIU, Jie , CELLA, James, Anthony , KATOH, Eisaku
发明人： YE, Qing , LIU, Jie , CELLA, James, Anthony , KATOH, Eisaku
IPC分类号： C09K11/06 , H05B33/14
CPC分类号： H05B33/14 , C09K11/06 , C09K2211/1022 , C09K2211/1029 , C09K2211/1033
摘要： An optoelectronic device comprises a cathode; an electron-transporting layer comprising a compound of formula I; formula I a light emitting-layer, and an anode; wherein R1 and R2 are independently at each occurrence, hydrogen, a C rC2U aliphatic radical a CyC2U aromatic radical or a d~ C-JO cycloaliphatic radical; R3 is H or alky]; a and b are, independently at each occurrence 0, or an integer ranging from 1 to 3; n is 2 or 3; and Ar is an aryl.
摘要翻译：光电器件包括阴极; 包含式I化合物的电子传输层; 式I为发光层和阳极; 其中R 1和R 2在每次出现时独立地为氢，C 1 -C 20脂族基团，CyC 2 U芳族基团或d〜C-JO脂环族基团; R3为H或烷基]; a和b各自独立地为0或1至3的整数; n为2或3; 并且Ar是芳基。

7. 发明申请

WO2010068479A1 AROMA RELEASING PACKAGE WITH MOVEABLY ENGAGEABLE PORTIONS 审中-公开
标题翻译： AROMA释放包装与可移动的工具
公开(公告)号：WO2010068479A1
公开(公告)日：2010-06-17
申请号：PCT/US2009/065870
申请日：2009-11-25
申请人： CADBURY ADAMS USA LLC , GLYDON, James, Anthony
发明人： GLYDON, James, Anthony
IPC分类号： B65D81/32
CPC分类号： B65D5/503 , B65D5/38 , B65D43/18 , B65D43/20 , B65D85/36 , B65D2203/12
摘要： Packages with at least two moveably engageable portions have one or more aroma providing substances placed at one or more contact points on the portions such that the one or more aroma providing substances are released when the portions are moved relative to each other. The packages can also include one or more aroma providing substances on one or more exterior surfaces of the packages so as to provide a consumer with an immediate sensory impression.
摘要翻译：具有至少两个可移动接合部分的包装具有一个或多个香味提供物质，其放置在部分上的一个或多个接触点处，使得当部分相对于彼此移动时，一种或多种香味提供物质被释放。包装还可以包括在包装的一个或多个外表面上提供物质的一种或多种香气，以便为消费者提供立即的感觉印象。

8. 发明申请

WO2010065515A1 ELECTRON-TRANSPORTING POLYMERS 审中-公开
标题翻译：电子传输聚合物
公开(公告)号：WO2010065515A1
公开(公告)日：2010-06-10
申请号：PCT/US2009/066215
申请日：2009-12-01
申请人： GENERAL ELECTRIC COMPANY , KONICA MINOLTA HOLDINGS, INC. , YE, Qing , CELLA, James, Anthony , KATOH, Eisaku , LIU, Jie
发明人： YE, Qing , CELLA, James, Anthony , KATOH, Eisaku , LIU, Jie
IPC分类号： C08F12/26 , C08F12/28
CPC分类号： C08F12/26 , C08F12/32 , C08F112/14 , H01L51/0003 , H01L51/004 , H01L51/0042 , H01L51/5012
摘要： The invention relates to polymers useful in optoelectronic devices and comprising structural unit of formula (I), wherein R 1 and R 2 are independently at each occurrence, hydrogen, a C 1 -C 20 aliphatic radical, a C 3 -C 20 aromatic radical, or a C 3 -C 20 cycloaliphatic radical; R 3 is H or alkyl; a and b are, independently at each occurrence 0, or an integer ranging from 1 to 3; and Ar is a direct bond or aryl.
摘要翻译：本发明涉及可用于光电子器件的聚合物，其包含式（I）的结构单元，其中R 1和R 2在每次出现时独立地为氢，C 1 -C 20脂族基，C 3 -C 20芳族基或C 3 -C 20 脂环族基团 R3是H或烷基; a和b各自独立地为0或1至3的整数; 并且Ar是直接键或芳基。

9. 发明申请

WO2010052198A1 ( PYRROLIDIN-2 -YL) PHENYL DERIVATIVES FOR USE IN THE TREATMENT OF PAIN 审中-公开
标题翻译：（吡咯烷-2-基）苯基衍生物用于治疗疼痛
公开(公告)号：WO2010052198A1
公开(公告)日：2010-05-14
申请号：PCT/EP2009/064490
申请日：2009-11-03
申请人： N.V. ORGANON , GROVE, Simon, James, Anthony , MISTRY, Ashvinkumar, Dhirubhai , PALIN, Ronald , MACLEAN, John, Kinnaird, Ferguson
发明人： GROVE, Simon, James, Anthony , MISTRY, Ashvinkumar, Dhirubhai , PALIN, Ronald , MACLEAN, John, Kinnaird, Ferguson
IPC分类号： C07D401/10 , A61K31/4439 , A61P25/02
CPC分类号： C07D401/10
摘要： The invention relates to (pyrrolidin-2-yl)phenyl derivatives having the general Formula (I), wherein R 1 is (C 1-4 )alkyl, halo(C 1-4 )alkyl, (C 1-4 )alkyloxy, or halo(C 1-4 )alkyloxy; R 2 is H, (C 1-4 )alkyl, halo(C 1-4 )alkyl, (C 1-4 )alkyloxy, halo(C 1-4 )alkyloxy or halogen; R 3 is H, (C 1-4 )alkyl or halo(C 1-4 )alkyl; R 4 is H, (C 1-4 )alkyl or halo(C 1-4 )alkyl; R 5 is H, (C 1-4 )alkyl or halo(C 1-4 )alkyl; or R4 and R5, when bonded to the same carbon atom, can together with the carbon atom form a spiro(C 3-6 )cycloalkyl group, optionally substituted with halogen; R 6 is H, (C 1-4 )alkyl, halo(C 1-4 )alkyl, (C 1-4 )alkyloxy, halo(C 1-4 )alkyloxy or halogen; or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of these (pyrrolidin-2-yl)phenyl derivatives for the treatment of pain, such as neuropathic pain or inflammatory pain.
摘要翻译：本发明涉及具有通式（I）的（吡咯烷-2-基）苯基衍生物，其中R 1为（C 1-4）烷基，卤代（C 1-4）烷基，（C 1-4）烷氧基或卤素 -4）烷氧基; R 2是H，（C 1-4）烷基，卤代（C 1-4）烷基，（C 1-4）烷氧基，卤代（C 1-4）烷氧基或卤素; R3是H，（C1-4）烷基或卤代（C1-4）烷基; R4是H，（C1-4）烷基或卤代（C1-4）烷基; R5是H，（C1-4）烷基或卤代（C1-4）烷基; 或R 4和R 5在与相同碳原子键合时可与碳原子一起形成任选被卤素取代的螺（C 3-6）环烷基; R 6为H，（C 1-4）烷基，卤代（C 1-4）烷基，（C 1-4）烷氧基，卤代（C 1-4）烷氧基或卤素; 或其药学上可接受的盐，包含其的药物组合物，以及这些（吡咯烷-2-基）苯基衍生物用于治疗疼痛如神经性疼痛或炎性疼痛的用途。

10. 发明申请

WO2010008486A2 PLURIPOTENT CELL LINES AND METHODS OF USE THEREOF 审中-公开
标题翻译： PLUIPOTENT细胞系及其使用方法
公开(公告)号：WO2010008486A2
公开(公告)日：2010-01-21
申请号：PCT/US2009/003783
申请日：2009-06-24
申请人： PARKINSONS INSTITUTE , THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , REIJO PERA, Renee, Ann , LANGSTON, J., William , SCHULE, Birgitt , PALMER, Theodore, D. , BYERS, Blake , NGUYEN, Ha, Nam , BYRNE, James, Anthony , CORD, Branden, John
发明人： REIJO PERA, Renee, Ann , LANGSTON, J., William , SCHULE, Birgitt , PALMER, Theodore, D. , BYERS, Blake , NGUYEN, Ha, Nam , BYRNE, James, Anthony , CORD, Branden, John
IPC分类号： C12N5/02
CPC分类号： C12N5/0619 , A61K35/12 , C12N7/00 , C12N2500/25 , C12N2500/46 , C12N2501/01 , C12N2501/115 , C12N2501/119 , C12N2501/13 , C12N2501/15 , C12N2501/392 , C12N2501/41 , C12N2501/50 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/70 , C12N2501/71 , C12N2503/02 , C12N2506/1307 , C12N2506/45 , C12N2740/15032 , C12Q1/6883 , C12Q2600/136 , G01N33/5023 , G01N33/5058 , G01N2333/47
摘要： Methods of generating cell lines with a sequence variation or copy number variation of a gene of interest, methods of use thereof, and cell lines with a sequence variation or copy number variation of a gene of interest are provided.
摘要翻译：提供了产生具有感兴趣基因的序列变异或拷贝数变异的细胞系的方法，其使用方法和具有感兴趣的基因的序列变异或拷贝数变异的细胞系。

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