专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US06458981B1 Composition and method for preparing amino acid chelate hydroxides free of interfering ions 有权
标题翻译：制备不含干扰离子的氨基酸螯合氢氧化物的组成和方法
公开(公告)号：US06458981B1
公开(公告)日：2002-10-01
申请号：US09686046
申请日：2000-10-11
申请人： Stephen D. Ashmead , David C. Wheelwright , Clayton Ericson , Mark Pedersen
发明人： Stephen D. Ashmead , David C. Wheelwright , Clayton Ericson , Mark Pedersen
IPC分类号： C07F300
CPC分类号： C07C227/16 , C07C229/76
摘要： The present invention relates to compositions and methods of preparing amino acid chelates that are essentially free of interfering ions. The composition is prepared by reacting in an aqueous solution, a calcium oxide and/or hydroxide, an amino acid, and a soluble metal sulfate salt at a ratio sufficient to allow substantially all of the ions present in solution to react forming a positively charged metal amino acid chelate having a hydroxide counter-ion, and calcium sulfate, and wherein the metal amino acid chelate has a ligand to metal molar ratio from 1:1 to 2:1.
摘要翻译：本发明涉及制备基本上不含干扰离子的氨基酸螯合物的组合物和方法。该组合物通过使水溶液，氧化钙和/或氢氧化物，氨基酸和可溶性金属硫酸盐以足以使溶液中存在的基本上所有离子反应形成带正电荷的金属的比例反应来制备具有氢氧化物抗衡离子的氨基酸螯合物和硫酸钙，其中金属氨基酸螯合物的配体与金属的摩尔比为1:1至2:1。

2. 发明授权

US06814895B2 Process for the synthesis of 1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-one 失效
标题翻译： 1-（3,5-双（三氟甲基）苯基）乙-1-酮的合成方法
公开(公告)号：US06814895B2
公开(公告)日：2004-11-09
申请号：US10451293
申请日：2004-01-28
申请人： Raymond Cvetovich , Tomoyuki Asai , Yoshiko Yodogawa
发明人： Raymond Cvetovich , Tomoyuki Asai , Yoshiko Yodogawa
IPC分类号： C07F300
CPC分类号： C07F3/02 , C07C17/12 , C07C45/004 , C07C49/80 , C07C25/13
摘要： The present invention is concerned with a novel process for the preparation of 1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-one (CAS 30071-93-3). This compound is useful as an intermediate in the synthesis of therapeutic agents.

3. 发明授权

US06294678B1 Treatment for cancer and compounds for use therewith 失效
标题翻译：癌症治疗及其使用化合物
公开(公告)号：US06294678B1
公开(公告)日：2001-09-25
申请号：US09005996
申请日：1998-01-12
申请人： George P. Sakalosky
发明人： George P. Sakalosky
IPC分类号： C07F300
CPC分类号： C07F9/94 , A61K31/00 , A61K31/375 , A61K31/555 , C07D307/62 , C07F3/003
摘要： A treatment for cancer and compounds for use therewith are provided. The compounds treat cancer by correcting a TATA box lesion in DNA that leads to the cancer's uncontrolled cell proliferation. The preferred compounds each contain strontium; iodine; ascorbic acid; and a diamagnetic ion, either bismuth, zinc, or potassium. These components orient the compound, transport it to the lesion, dissociate the aberrational bonds of the lesion, hydrogenate the dissociated TATA nucleotides at the lesion, and reconvert the lesion's chemical structure to that of normal DNA.
摘要翻译：提供癌症治疗及其使用化合物。该化合物通过校正导致癌症不受控制的细胞增殖的DNA中的TATA盒损伤来治疗癌症。优选的化合物各自含有锶; 碘; 抗坏血酸; 和抗磁离子，铋，锌或钾。这些成分使化合物定向，将其转运到损伤处，解离病变的异常结合，使损伤处解离的TATA核苷酸氢化，并将病变的化学结构重新转化为正常DNA。

4. 发明授权

US06426424B1 Composition and method for preparing granular amino acid chelates and complexes 有权
标题翻译：制备颗粒状氨基酸螯合物和配合物的组合物和方法
公开(公告)号：US06426424B1
公开(公告)日：2002-07-30
申请号：US09686413
申请日：2000-10-11
申请人： Stephen D. Ashmead , Mark Pedersen
发明人： Stephen D. Ashmead , Mark Pedersen
IPC分类号： C07F300
CPC分类号： C07D233/64 , C07C227/16 , C07C319/20 , C07C229/76 , C07C323/58
摘要： Compositions and methods of preparing amino acid chelates and complexes are disclosed and described. Specifically, by (a) blending hydrated metal sulfate salts, amino acid ligands, and reaction modifiers; (b) confining the particulate blend in an enclosed environment; and (c) applying heat to the particulate blend in the enclosed environment causing the waters of hydration of the metal sulfate salt to be released into the enclosed environment causing a reaction resulting in the formation of a granular amino acid chelate or complex by effecting the reaction between functional electron rich groups of the amino acid ligand and a metal ion of the metal sulfate salt. The waters of hydration serve to provide the water necessary to enable a bonding reaction to take place between the electron rich functional groups of the amino acid ligand and the metal ion of the hydrated metal sulfate salt.
摘要翻译：公开和描述了制备氨基酸螯合物和络合物的组合物和方法。具体地，通过（a）水合金属硫酸盐，氨基酸配体和反应改性剂的混合; （b）将颗粒状混合物限制在封闭的环境中; 和（c）在封闭的环境中对颗粒混合物进行加热，导致金属硫酸盐的水合水被释放到封闭环境中，导致通过进行反应而导致形成颗粒状氨基酸螯合物或络合物的反应在氨基酸配体的功能性富电子基团与金属硫酸盐的金属离子之间。水合水用于提供使氨基酸配体的富含电子的官能团和水合金属硫酸盐的金属离子之间发生结合反应所需的水。

5. 发明授权

US06348166B1 Method for producing di-organo alkaline-earth compounds 失效
标题翻译：二有机碱土类化合物的制造方法
公开(公告)号：US06348166B1
公开(公告)日：2002-02-19
申请号：US09555593
申请日：2000-05-31
申请人： Konrad Knoll , Hans-Herbert Brintzinger , Armin Weeber
发明人： Konrad Knoll , Hans-Herbert Brintzinger , Armin Weeber
IPC分类号： C07F300
CPC分类号： C07F3/02 , C07F3/00 , C08F12/04 , C08F4/50
摘要： A process for the preparation of bisorganoalkaline earth metal compounds comprises reacting an organometallic compound RnM2 with an alkaline earth metal salt M1Xm.
摘要翻译：制备双有机碱土金属化合物的方法包括使有机金属化合物RnM2与碱土金属盐M1Xm反应。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式