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    • 1. 发明授权
    • Aminoalkylethers; composition and method of use
    • 氨基烷基醚; 组成和使用方法
    • US4049825A
    • 1977-09-20
    • US734358
    • 1976-10-20
    • Johan Gootjes
    • Johan Gootjes
    • C07C9/20
    • Diphenylmethoxyethylamines of the general formula ##STR1## in which R.sub.1 represents a fluorine, bromine or chlorine atom, R.sub.2 represents a hydrogen or fluorine atom and R.sub.3 represents a hydrogen, fluorine or chlorine atom, with the provisos that R.sub.3 is a hydrogen atom when R.sub.2 is a fluorine atom, R.sub.1 is a fluorine atom when R.sub.3 is a chlorine atom and R.sub.1 is a fluorine or bromine atom when R.sub.2 and R.sub.3 both are hydrogen atoms, and their non-toxic acid addition salts are disclosed. The compounds have dopaminergic properties and their use is indicated for treating the Parkinson syndrome. Compositions for such use are disclosed.
    • 通式II“IMAGE”的二苯基甲氧基乙胺,其中R 1表示氟,溴或氯原子,R 2表示氢或氟原子,R 3表示氢,氟或氯原子,条件是当R 2为R 2时,R 3为氢原子 当R 2是氢原子时,R 1是氟原子,当R 2和R 2都是氢原子时,R 1是氟或溴原子,并且它们的无毒酸加成盐被公开。 这些化合物具有多巴胺能性质,其用途用于治疗帕金森综合征。 公开了用于此类用途的组合物。