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1. 发明申请

US20130059998A1 Poly(Ester Amide) Macromers and Polymers Thereof 审中-公开
标题翻译：聚（酯酰胺）大分子单体和聚合物
公开(公告)号：US20130059998A1
公开(公告)日：2013-03-07
申请号：US13583426
申请日：2011-03-09
申请人： Chih-Chang Chu , Mingxiao Deng
发明人： Chih-Chang Chu , Mingxiao Deng
IPC分类号： C08F236/20 , C07C235/74 , C07C309/21 , C07C235/12
摘要： Amino acid-based poly(ester amide) (PEA) macromers (e.g., functional PEA macromers) and methods for preparing amino acid-based poly(ester amide) (PEA) macromers. The functional PEA macromers can comprise functional groups such as hydroxyl, amine, sulfonic acids, carboxyl, thiol and acryloyl at the two terminuses of the PEA macromers. The content of the terminal functional groups on the macromers can be precisely controlled by adjusting the molar ratio of reactive monomers. The resulting versatility of these new functional PEA macromers can be used to fabricate a wide range of PEAs and PEA hybrid derivatives with very different chemical, physical, mechanical, thermal and biological properties. The functional PEA macromers can also be polycondensed into forming block PEA polymers.
摘要翻译：基于氨基酸的聚（酯酰胺）（PEA）大分子单体（例如功能性PEA大分子单体）和制备基于氨基酸的聚（酯酰胺）（PEA）大分子单体的方法。功能性PEA大分子单体可以在PEA大分子单体的两个末端包含官能团，例如羟基，胺，磺酸，羧基，硫醇和丙烯酰基。大分子单体末端官能团的含量可以通过调整反应性单体的摩尔比来精确控制。这些新的功能性PEA大分子单体的多功能性可用于制造具有非常不同化学，物理，机械，热和生物学特性的各种各样的PEAs和PEA杂化衍生物。功能性PEA大分子单体也可以缩聚成成型块PEA聚合物。

2. 发明授权

US5869725A Derivatives of aminosulfonic acids, utilization of the same in the synthesis of pseudopeptides and process for their preparation 失效
标题翻译：氨基磺酸的衍生物，在合成假肽中使用相同的方法及其制备方法
公开(公告)号：US5869725A
公开(公告)日：1999-02-09
申请号：US737379
申请日：1996-10-30
申请人： Cesare Gennari , Donatella Potenza , Barbara Salom
发明人： Cesare Gennari , Donatella Potenza , Barbara Salom
IPC分类号： C07C303/02 , C07C303/36 , C07C309/21 , C07C309/69 , C07C309/77 , C07C309/83 , C07C311/34 , C07C311/47 , C07D207/08 , C07F7/18
CPC分类号： C07D207/08 , C07C309/69 , C07C311/47 , Y02P20/55
摘要： Derivatives of gamma-amino-alpha,beta-unsaturated sulfonic acids, a process for the preparation of the same and their utilization in the synthesis of pseudopeptides characterized by the presence of at least a sulfonamide type bond conjugated to a double bond are described.
摘要翻译： PCT No.PCT / EP95 / 01788 Sec。 371日期1996年10月30日 102（e）日期1996年10月30日PCT提交1995年5月11日PCT公布。公开号WO95 / 31433 日期1995年11月23日γ-氨基-α，β-不饱和磺酸的衍生物，其制备方法及其在合成伪肽中的应用，其特征在于至少存在与双键结合的磺酰胺型键债券被描述。

3. 发明授权

US11370749B2 Method for treating a suspension of solid particles in water using a (co)polymer of a hydrated crystalline form of 2-acrylamido-2-methylpropanesulfonic acid 有权
公开(公告)号：US11370749B2
公开(公告)日：2022-06-28
申请号：US16494587
申请日：2018-03-19
申请人： SPCM SA
发明人： Cédrick Favero , Johann Kieffer , Frédéric Daguerre
IPC分类号： C07C309/15 , C02F1/56 , C02F11/147 , C09K8/588 , C09K8/80 , E21B43/16 , E21B43/26 , C08F20/58 , C09K8/68 , C02F103/10 , C09K8/88 , C07C309/21 , C07C303/02 , C07C303/44 , C08F20/56
摘要： The present invention relates to a method for the treatment of a suspension of solid particles in water using water-soluble (co)polymers made from the hydrated crystalline form of 2-acrylamido-2-methylpropane sulfonic acid or of at least one of the salts thereof. This method is particularly useful for treating residues resulting from the mining industry.

4. 发明授权

US11008362B2 Malonyl-coenzyme A mimics as fatty acid synthase inhibitors and methods of use 有权
公开(公告)号：US11008362B2
公开(公告)日：2021-05-18
申请号：US16432147
申请日：2019-06-05
申请人： Purdue Research Foundation
发明人： Jeremy R. Lohman , Lee M. Stunkard
IPC分类号： C07H19/207 , C07F9/09 , C07C233/13 , C07C309/21
摘要： The present disclosure generally relates to novel compounds as a fatty acid synthase inhibitor useful for the treatment of infection diseases, cancers, or metabolic diseases that malfunction of fatty acid synthase is involved. In particular this present invention directs to malonyl-coenzyme A (CoA) mimetics and methods of use thereof. The invention described herein also pertains to pharmaceutical compositions and methods for treating diseases in mammals using compounds disclosed herein.

5. 发明申请

US20170008918A1 NOVEL CYP-EICOSANOID DERIVATIVES 审中-公开
标题翻译：新型CYP-EICOSANOID衍生物
公开(公告)号：US20170008918A1
公开(公告)日：2017-01-12
申请号：US15113139
申请日：2015-01-21
申请人： MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN , BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人： Wolf-Hagen Schunck , Dominik Mueller , Robert Fischer , Gerd Wallukat , Anne Konkel , John Russell Falck
IPC分类号： C07F9/38 , C07C311/51 , C07F9/40 , C07C309/21 , C07D291/04 , C07C323/41 , C07D277/82
CPC分类号： C07F9/3826 , C07C309/21 , C07C311/51 , C07C323/41 , C07D277/82 , C07D291/04 , C07F9/3882 , C07F9/4015
摘要： The present invention relates to compounds according to general formula (I) which are analogues of epoxymetabolites produced by cytochrome P450 (CYP) enzymes from omega-3 (n-3) polyunsaturated fatty acids (PUFAs). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for C the treatment or prevention of conditions and diseases associated with inflammation, proliferation, hypertension, coagulation, immune function, pathologic angiogenesis, heart failure and cardiac arrhythmias.
摘要翻译：本发明涉及通式（I）的化合物，它是由ω-3（n-3）多不饱和脂肪酸（PUFA）的细胞色素P450（CYP）酶产生的环氧代谢产物的类似物。本发明还涉及含有这些化合物中的一种或多种的组合物以及这些化合物或组合物用于治疗或预防与炎症，增殖，高血压，凝血，免疫功能，病理性血管发生，心脏相关的病症和疾病的用途失败和心律失常。

6. 发明授权

US10998574B2 Non-aqueous electrolyte magnesium secondary battery 有权
公开(公告)号：US10998574B2
公开(公告)日：2021-05-04
申请号：US15517349
申请日：2015-10-08
申请人： NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
发明人： Keigo Kubota , Kenichi Teramoto , Rie Ooyabu , Hajime Matsumoto
IPC分类号： H01M10/054 , H01M10/056 , H01M10/0568 , H01M10/0569 , H01M4/38 , H01M4/48 , C07C211/63 , C07C309/06 , C07C309/21 , C07F9/54 , H01M4/46
摘要： This invention provides a non-aqueous electrolyte magnesium secondary battery comprising a positive electrode, a negative electrode, a separator, and a non-aqueous electrolyte, the non-aqueous electrolyte comprising [N(SO2CF3)2]− as an anion, and Mg2+ and/or an organic onium cation as a cation.

7. 发明授权

US10538484B1 Maleamic acid monomer and preparation method and use thereof 有权
公开(公告)号：US10538484B1
公开(公告)日：2020-01-21
申请号：US16129285
申请日：2018-09-12
申请人： China Petroleum & Chemical Corporation , SINOPEC Research Institute of Petroleum Engineering
发明人： Xiaohua Yang , Yongxue Lin , Jian He , Lin Wang , Haibo Wang , Fan Yang , Zhoujun Li , Xiaoqiang Dong
IPC分类号： C07C235/28 , C07H5/04 , C07C231/02 , C07C309/21 , C07C309/29 , C07C235/30
摘要： A maleamic acid monomer, and a preparation method and a use of the maleamic acid monomer. The structural formula of the monomer is as follows: formula (1), wherein, R is selected from The maleamic acid monomer provided in the present invention may be used as a comonomer to prepare temperature-tolerant and calcium salt-tolerant polymers.

8. 发明授权

US08299294B2 Process for producing vinyl sulfonic acid 有权
标题翻译：制备乙烯基磺酸的方法
公开(公告)号：US08299294B2
公开(公告)日：2012-10-30
申请号：US12448607
申请日：2007-12-26
申请人： Hiroshi Akikaze , Takehiko Miyai
发明人： Hiroshi Akikaze , Takehiko Miyai
IPC分类号： C07C309/21
CPC分类号： C07C303/22 , C07C303/44 , C07C309/20
摘要： The subject invention provides: a method for producing vinyl sulfonic acid, comprising conducting demetallation of vinyl sulfonate salt, wherein the demetallation rate is not less than 95% according to the following formula: Demetallation rate(%)={(acid value after demetallation)/(acid value before demetallation)}×100; a method for producing vinyl sulfonic acid, comprising conducting demetallation of vinyl sulfonate salt, wherein demetallation is carried out using a strongly acidic ion exchange resin; and said method further comprising the step of purifying a product of the demetallation using a thin film evaporator.
摘要翻译：本发明提供：一种乙烯基磺酸的制造方法，其特征在于，进行乙烯基磺酸盐的脱金属化，其中脱金属率不低于95％根据下式：脱金属率（％）= {（脱金属后的酸值） /（脱金属前的酸值）}×100; 一种生产乙烯基磺酸的方法，包括进行乙烯基磺酸盐的脱金属，其中使用强酸性离子交换树脂进行脱金属化; 并且所述方法还包括使用薄膜蒸发器纯化脱金属产品的步骤。

9. 发明授权

US11130772B2 CYP-eicosanoid derivatives 有权
公开(公告)号：US11130772B2
公开(公告)日：2021-09-28
申请号：US15113139
申请日：2015-01-21
申请人： MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN , BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人： Wolf-Hagen Schunck , Dominik Mueller , Robert Fischer , Gerd Wallukat , Anne Konkel , John Russell Falck
IPC分类号： C07F9/38 , C07C309/21 , C07C311/51 , C07C323/41 , C07D277/82 , C07D291/04 , C07F9/40
摘要： The present invention relates to compounds according to general formula (I) which are analogues of epoxymetabolites produced by cytochrome P450 (CYP) enzymes from omega-3 (n-3) polyunsaturated fatty acids (PUFAs). The present invention further relates to compositions containing one or more of these compounds and to the use of these compounds or compositions for the treatment or prevention of conditions and diseases associated with inflammation, proliferation, hypertension, coagulation, immune function, pathologic angiogenesis, heart failure and cardiac arrhythmias.

10. 发明申请

US20170294675A1 NON-AQUEOUS ELECTROLYTE MAGNESIUM SECONDARY BATTERY 审中-公开
公开(公告)号：US20170294675A1
公开(公告)日：2017-10-12
申请号：US15517349
申请日：2015-10-08
申请人： NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
发明人： Keigo KUBOTA , Kenichi TERAMOTO , Rie OOYABU , Hajime MATSUMOTO
IPC分类号： H01M10/054 , C07C309/21 , C07C211/63 , H01M4/46 , C07F9/54 , C07C309/06 , H01M10/056
CPC分类号： H01M10/054 , C07C211/63 , C07C309/06 , C07C309/21 , C07F9/5407 , H01M4/381 , H01M4/466 , H01M4/483 , H01M10/056 , H01M10/0568 , H01M10/0569 , H01M2300/0045
摘要： This invention provides a non-aqueous electrolyte magnesium secondary battery comprising a positive electrode, a negative electrode, a separator, and a non-aqueous electrolyte, the non-aqueous electrolyte comprising [N(SO2CF3)2]− as an anion, and Mg2+ and/or an organic onium cation as a cation.

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