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1. 发明授权

US06597943B2 Method of using spectral measures to distinguish among atrialfibrillation, atrial-flutter and other cardiac rhythms 有权
标题翻译：使用光谱测量法区分心房颤动，心房颤动和其他心律的方法
公开(公告)号：US06597943B2
公开(公告)日：2003-07-22
申请号：US09748462
申请日：2000-12-26
申请人： Basel Taha , Shankara Reddy , Joel Xue
发明人： Basel Taha , Shankara Reddy , Joel Xue
IPC分类号： A61B5046
CPC分类号： A61B5/04525 , A61B5/0464
摘要： A method and apparatus are provided for differentiating among atrial-flutter, atrial-fibrillation and other cardiac rhythms. The method includes the steps of estimating a spectral entropy of atrial cardiac activity from an electrocardiogram of a patient and determining that the patient has atrial fibrillation when the spectral entropy is greater than a predetermined value.
摘要翻译：提供了一种用于区分心房颤动，心房颤动和其他心律的方法和装置。该方法包括以下步骤：从患者的心电图估计心房心脏活动的频谱熵，并且当频谱熵大于预定值时确定患者具有心房颤动。

2. 发明授权

US06834203B2 System and method for prioritizing multiple health disorders for use in automated patient care 有权
标题翻译：用于优先考虑多种健康障碍以用于自动病人护理的系统和方法
公开(公告)号：US06834203B2
公开(公告)日：2004-12-21
申请号：US10210418
申请日：2002-07-31
申请人： Gust H. Bardy
发明人： Gust H. Bardy
IPC分类号： A61B5046
CPC分类号： A61N1/37282 , A61B5/0002 , A61N1/3627 , G06F19/00 , G06F19/324 , G06F19/3418 , G06F19/3481 , G06Q50/22 , G16H10/60 , G16H15/00 , G16H50/20 , Y10S128/923
摘要： A system and method for prioritizing multiple health disorders for use in automated patient care is described. A plurality of monitoring sets are retrieved from a database. Each of the monitoring sets include stored measures relating to patient information recorded and derived on a substantially continuous basis. A patient status change is determined by comparing at least one stored measure from each of the monitoring sets to at least one other stored measure with both stored measures relating to the same type of patient information. Each patient status change is ordered in temporal sequence from least recent to most recent. A plurality of health disorder candidates categorized by quantifiable physiological measures of pathophysiologies indicative of each respective health disorder are evaluated and the health disorder candidate with the pathophysiology most closely matching those patient status changes which occurred least recently is identified.
摘要翻译：描述了将多种健康障碍的优先级用于自动化患者护理中的系统和方法。从数据库检索多个监视集。每个监测组包括与基本上连续的基础上记录和导出的患者信息相关的存储措施。通过将来自每个监测组的至少一个存储的测量值与至少一个其他存储的测量值相比较来确定患者状态变化，其中存储的测量值与相同类型的患者信息相关。每个患者状态变化按照从最近到最近的时间顺序排列。对通过可量化的生理指标进行分类的多种健康障碍候选者进行评价，所述健康障碍候选者具有与每个相应的健康障碍相关的病理生理学最接近匹配的病理生理学指标。

3. 发明授权

US06223073B1 Noninvasive method for identifying coronary disfunction utilizing electrocardiography derived data 有权
标题翻译：使用心电图导出数据识别冠状动脉障碍的无创方法
公开(公告)号：US06223073B1
公开(公告)日：2001-04-24
申请号：US09399602
申请日：1999-09-20
申请人： Ronald D. Seegobin
发明人： Ronald D. Seegobin
IPC分类号： A61B5046
CPC分类号： A61B5/04525 , A61B5/7264
摘要： A method of analyzing experimentally derived electrocardiograph (ECG) data, and system for practicing said method, which allow tracking of subject cardiac status change and which allow accurate catagorization of subjects into various abnormal and normal classifications is disclosed. The presently preferred embodiment applies an algorithm which compares representative parameter, (eg. root-mean-square (RMS) mean), values derived from analysis of a selected portion of a single cycle of an ECG PQRST waveform obtained from investigation of a subject, to similarly derived representative parameter, (eg. RMS mean and RMS standard deviation), values for a composite ECG waveform present in a compiled data bank derived from (ECG) investigation of numerous subjects who were documented as normals, typically in each of a plurality of frequency range bands. A highly diagnostic numerical “Score” is calculated by addition of “Score” components found to be acceptable under certain mathematical criteria, and provided by the algorithm. Visually interpretable time domain and power spectral density plots enhance the method. In addition, comparison of the calculated “Score” to subject cardiac ejection fraction provides indication of risk for sudden death as does the presence of “rhomboids” following a QRS complex in frequency domain plots. The present method is directly adapted to tracking subject cardiac status change by substituting a baseline subject data set for the normal population data set.normal population data set.
摘要翻译：公开了一种分析实验导出的心电图（ECG）数据的方法，以及用于实施所述方法的系统，其允许对主体心脏状态变化的跟踪，并且允许受试者准确地分类为各种异常和正常分类。目前优选的实施例应用一种比较代表参数（例如，均方根（RMS）均值）的算法，从对主题调查获得的ECG PQRST波形的单个周期的选定部分的分析得到的值，（例如，RMS平均值和RMS标准偏差），存在于编码数据库中的复合心电图波形的值，该编码数据库来源于（多个被记录为法线）的多个主题的（ECG）调查，通常在多个的频段范围。通过添加在某些数学标准下被认为是可接受的并且由该算法提供的“Score”分量来计算高度诊断数字“Score”。视觉上可解释的时域和功率谱密度图增强了该方法。此外，计算的“得分”与受试者心脏射血分数的比较提供了猝死风险的指示，如在频域图中的QRS复合物之后存在“菱形”。本方法直接适用于通过将正常人群数据集的正态分布数据集替换为基线主体数据集来追踪对象心脏状态变化。

4. 发明授权

US06253102B1 System for displaying cardiac arrhythmia data 有权
标题翻译：显示心律失常数据的系统
公开(公告)号：US06253102B1
公开(公告)日：2001-06-26
申请号：US09572410
申请日：2000-05-11
申请人： William Hsu , Douglas J. Lang
发明人： William Hsu , Douglas J. Lang
IPC分类号： A61B5046
CPC分类号： A61N1/37247 , A61N1/3702 , G06F19/00 , G16H15/00 , G16H40/63 , G16H50/20
摘要： A medical device system and method of plotting symbols representing complexes of selected arrhythmic events on an interactive display screen, for organizing, displaying and interacting with a patient's recorded arrhythmia episodes. Stored arrhythmic episode are selected from a plurality of arrhythmic episodes, where the stored arrhythmic episode having a plurality of complexes. A similarity value and a dissimilarity value is calculated for each complex of the plurality of complexes of the selected arrhythmic episode with respect to normal sinus rhythm complexes. Symbols representing the arrhythmic complexes are then plotted as a function of the calculated similarity values and the dissimilarity values on an interactive display screen. Additional information relating to the arrhythmic event is elicited through interacting with the symbols displayed on the interactive display screen.
摘要翻译：一种用于在交互式显示屏幕上绘制表示所选择的心律不齐事件的复合物的符号的图形化的医疗装置系统和方法，用于组织，显示和与患者记录的心律失常发作相互作用。存储的心律失常发作选自多种心律失常发作，其中存储的心律不齐事件具有多个复合物。对于所选择的心律失常发作的多个复合物相对于正常窦性心律复合物的每个复合物计算相似值和不相似性值。然后将表示心律不齐复合物的符号作为在交互式显示屏幕上计算的相似度值和不相似性值的函数来绘制。通过与交互式显示屏幕上显示的符号进行交互，引发与心律失常事件相关的附加信息。

5. 发明授权

US06171257B2 Method and system for predicting the immediate success of a defibrillatory shock during cardiac arrest 有权
标题翻译：用于预测心脏骤停期间除颤器休克的直接成功的方法和系统
公开(公告)号：US06171257B2
公开(公告)日：2001-01-09
申请号：US09385537
申请日：1999-08-30
申请人： Max Harry Weil , Wanchun Tang , Joe Bisera
发明人： Max Harry Weil , Wanchun Tang , Joe Bisera
IPC分类号： A61B5046
CPC分类号： A61N1/39 , A61N1/36592 , A61N1/3925
摘要： A method and system (30, 50) for predicting the immediate success of a defibrillatory shock during cardiac arrest are shown. The sequencing of cardiopulmonary resuscitation is determined by an electronic computer (80) based on the probability of success as determined by a comparison of the amplitude spectrum area or the power spectrum area of an electrocardiogram sample and to empirical data. When the probability of successful resuscitation is 80% or greater, immediate defibrillation is implemented. When the probability of success is 20% or less, advanced cardiopulmonary resuscitation is implemented. When the probability of success remains greater than 20% but less than 80% for a period of four minutes, the patient is also defibrillated.
摘要翻译：示出了用于预测心脏骤停期间除颤器休克的直接成功的方法和系统（30,50）。基于通过心电图样本的振幅谱面积或功率谱面积的比较确定的成功概率与经验数据，由电子计算机（80）确定心肺复苏的顺序。当成功复苏的概率为80％以上时，立即进行除颤。当成功的概率在20％以下时，进行先进的心肺复苏。当成功的概率在四分钟的时间内保持大于20％但小于80％时，患者也被除颤。

6. 发明授权

US06704595B2 Automated method for diagnosing and monitoring the outcomes of atrial fibrillation 有权
标题翻译：用于诊断和监测心房颤动结果的自动化方法
公开(公告)号：US06704595B2
公开(公告)日：2004-03-09
申请号：US09929229
申请日：2001-08-13
申请人： Gust H. Bardy
发明人： Gust H. Bardy
IPC分类号： A61B5046
CPC分类号： A61B5/0452 , A61B5/0031 , A61B5/046 , A61N1/3622 , A61N1/37282 , G06F19/00 , Y10S128/923
摘要： An automated system and method for diagnosing and monitoring the outcomes of atrial fibrillation is described. A plurality of monitoring sets is retrieved from a database. Each of the monitoring sets include recorded measures relating to patient information recorded on a substantially continuous basis. A patient status change is determined in response to an atrial fibrillation diagnosis by comparing at least one recorded measure from each of the monitoring sets to at least one other recorded measure. Both recorded measures relate to the same type of patient information. Each patient status change is tested against an indicator threshold corresponding to the same type of patient information as the recorded measures which were compared. The indicator threshold corresponds to a quantifiable physiological measure of a pathophysiology resulting from atrial fibrillation.
摘要翻译：描述了用于诊断和监测心房颤动结果的自动化系统和方法。从数据库检索多个监视集。每个监测组包括与基本上连续的基础上记录的患者信息有关的记录措施。通过将来自每个监测组的至少一个记录的测量值与至少一个其他记录的测量值进行比较来响应于心房颤动诊断来确定患者状态变化。两种记录的措施都与相同类型的患者信息相关。根据与所比较的记录措施相同类型的患者信息的指标阈值测试每个患者状态变化。指标阈值对应于由房颤引起的病理生理学的可量化的生理测量。

7. 发明授权

US06701183B2 Long term atrial fibrillation monitor 有权
标题翻译：长期房颤监测
公开(公告)号：US06701183B2
公开(公告)日：2004-03-02
申请号：US09827551
申请日：2001-04-06
申请人： Robert L. Baker , Jack E. Lohman
发明人： Robert L. Baker , Jack E. Lohman
IPC分类号： A61B5046
CPC分类号： A61B5/046
摘要： An atrial fibrillation monitor provides hand-contacting electrodes to allow daily ECG measurements of a patient without cumbersome electrode connection to the patient. ECG data may be diagnosed by the monitor to indicate likelihood of atrial fibrillation and an indication provided to the patient ECG data based on that indication may be forwarded to a physician or other healthcare professional for a review.
摘要翻译：心房颤动监测器提供手接触电极，以允许患者的每日ECG测量，而不会对患者造成麻烦的电极连接。 ECG数据可以由监视器诊断以指示房颤的可能性，并且基于该指示提供给患者ECG数据的指示可以被转发给医师或其他医疗保健专业人员进行审查。

8. 发明授权

US06487443B2 Prioritized rule based method and apparatus for diagnosis and treatment of arrhythmias 失效
标题翻译：用于诊断和治疗心律失常的优先规则方法和装置
公开(公告)号：US06487443B2
公开(公告)日：2002-11-26
申请号：US09819433
申请日：2001-03-28
申请人： Walter H. Olson , William F. Kaemmerer , Mark L. Brown
发明人： Walter H. Olson , William F. Kaemmerer , Mark L. Brown
IPC分类号： A61B5046
CPC分类号： A61N1/3622 , A61B5/042 , A61B5/046 , A61B5/0464 , A61B5/7264
摘要： An implantable antiarrhythmia device which detects and classifies arrhythmias of the human heart, and delivers appropriate therapy. The device employs a method of arrhythmia classification based on a set of prioritized rules, each of the rules defining a plurality of criteria based upon characteristics of sensed depolarizations of heart tissue, each rule being met when the criteria associated with the rule are met. Some rules, when met, trigger delivery of antiarrhythmia therapy. Other rules, when met, inhibit delivery of antiarrhythmia therapy. The rules may be met simultaneously, and if so, the highest priority rule governs the behavior of the device.
摘要翻译：一种可植入的抗心律失常装置，用于检测和分类人心脏的心律失常，并提供适当的治疗。该装置采用基于一组优先规则的心律失常分类方法，每个规则基于感测到的心脏组织去极化的特征来定义多个标准，当满足与规则相关联的标准时，满足每个规则。一些规则，当遇到时，触发了抗心律失常治疗的传递。遇到其他规则时，抑制抗心律失常治疗。可以同时满足规则，如果是，则最高优先级规则控制设备的行为。

9. 发明授权

US06178347B1 Apparatus for frequency analysis of atrial fibrillation 有权
标题翻译：心房颤动频率分析装置
公开(公告)号：US06178347B1
公开(公告)日：2001-01-23
申请号：US09180238
申请日：1999-01-08
申请人： Bertil Olsson
发明人： Bertil Olsson
IPC分类号： A61B5046
CPC分类号： A61N1/3925 , A61N1/395
摘要： An apparatus for frequency analysis of atrial fibrillation, as a measure of the state of the illness which includes a device for registration of electrical signals from the heart of a patient, a device for separating a signal originating from the atrium and a device for frequency analysis of the atrial signal. Preferably, the separating device has a system for identification of signals originating from the ventricles, a system for classification of the ventricular signals, a system for formation of the average of the classified ventricular signals and a system for subtracting the averaged, classified ventricular signals from the total registered signal, in order to obtain the atrial signal. Preferably, the registration device comprises electrodes to be placed on the patient and for simultaneous registration of conventional ECG signals.
摘要翻译：用于心房颤动频率分析的装置，作为疾病状态的量度，其包括用于从患者心脏登记电信号的装置，用于分离源自心房的信号的装置和用于频率分析的装置的心房信号。优选地，分离装置具有用于识别源自心室的信号的系统，用于分类心室信号的系统，用于形成分类的心室信号的平均值的系统，以及用于从平均分类的心室信号总登记信号，以获得心房信号。优选地，登记装置包括要放置在患者身上并用于同时登记常规ECG信号的电极。

10. 发明授权

US06826425B2 System and method for providing diagnosis and monitoring of atrial fibrillation for use in automated patient care 有权
标题翻译：用于诊断和监测房颤的系统和方法，用于自动化患者护理
公开(公告)号：US06826425B2
公开(公告)日：2004-11-30
申请号：US10152650
申请日：2002-05-20
申请人： Gust H. Bardy
发明人： Gust H. Bardy
IPC分类号： A61B5046
CPC分类号： A61B5/0452 , A61B5/0031 , A61B5/046 , A61N1/3622 , A61N1/37282 , G06F19/00 , Y10S128/923
摘要： An automated system and method for diagnosing and monitoring the outcomes of atrial fibrillation is described. A plurality of monitoring sets is retrieved from a database. Each of the monitoring sets include recorded measures relating to patient information recorded on a substantially continuous basis. A patient status change is determined in response to an atrial fibrillation diagnosis by comparing at least one recorded measure from each of the monitoring sets to at least one other recorded measure. Both recorded measures relate to the same type of patient information. Each patient status change is tested against an indicator threshold corresponding to the same type of patient information as the recorded measures which were compared. The indicator threshold corresponds to a quantifiable physiological measure of a pathophysiology resulting from atrial fibrillation.
摘要翻译：描述了用于诊断和监测心房颤动结果的自动化系统和方法。从数据库检索多个监视集。每个监测组包括与基本上连续的基础上记录的患者信息有关的记录措施。通过将来自每个监测组的至少一个记录的测量值与至少一个其他记录的测量值进行比较来响应于心房颤动诊断来确定患者状态变化。两种记录的措施都与相同类型的患者信息相关。根据与所比较的记录措施相同类型的患者信息的指标阈值测试每个患者状态变化。指标阈值对应于由房颤引起的病理生理学的可量化的生理测量。

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