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1. 发明授权

US06984239B1 Thrombectomy and tissue removal method 失效
标题翻译：血栓切除术和组织清除法
公开(公告)号：US06984239B1
公开(公告)日：2006-01-10
申请号：US08351602
申请日：1994-12-08
申请人： William J. Drasler , Robert G. Dutcher , Mark L. Jenson , Joseph M. Thielen , Emmanuil I. Protonotarios
发明人： William J. Drasler , Robert G. Dutcher , Mark L. Jenson , Joseph M. Thielen , Emmanuil I. Protonotarios
IPC分类号： A61B12/32
CPC分类号： A61B17/32037 , A61B17/3203
摘要： A device for removing a thrombus or other tissue deposit from the cardiovascular system, natural or synthetic tubule or cavity found in the human body of a patient without the need to surgically access the location of the thrombus or other tissue deposit via a cut-down or other surgical procedure. A flexible metal or high pressure plastic tube conveys an extremely high pressure stream of sterile saline or other physiologic solution to at least one jet at the distal end of the catheter. At least one jet is directed at the opening of a large exhaust lumen or other target. The jet(s) is responsible for providing a localized negative pressure which entrains tissue into the jet from break-up of the debris. This jet(s) can also provide stagnation pressure in the exhaust lumen which drives the tissue or thrombotic debris out of the exhaust lumen. Operation of the device with tip pressure greater than 500 psi provides this device with the entrainment and exhaust characteristics which contribute to its effectiveness. The rate of exhaust of tissue debris is metered to ensure minimal local impact on the vasculature at the site of the thrombus deposit. A fluid metering means, such as a roller pump, controls the rate of exhaust such that it is in balance with the saline input or can be adjusted to be greater or less than the input. A positive displacement pump operating at steady or pulsatile flow provides the high pressure saline to the tip of the catheter.
摘要翻译：一种用于从心血管系统去除血栓或其他组织沉积物的装置，在患者的人体中发现的天然或合成的小管或腔，而不需要经由切口或外科手术来进入血栓或其他组织沉积物的位置其他外科手术。柔性金属或高压塑料管将非常高压的无菌盐水或其他生理溶液流输送到导管远端处的至少一个射流。至少一个射流指向大排气腔或其他靶的开口。喷气机负责提供局部的负压，其将组织夹带到喷射器中从碎片的分解中。这种喷射器还可以在排气腔中提供停滞压力，其将组织或血栓形成的碎片驱动出排出管腔。尖端压力大于500 psi的设备的操作为该设备提供了有助于其有效性的夹带和排气特性。计量组织碎片的排气速率，以确保局部对血栓沉积部位脉管系统的局部影响最小。诸如辊式泵的流体计量装置控制排气速率，使其与盐水输入平衡，或者可以将其调节为大于或小于输入。以稳定或脉动流动运行的容积式泵向导管的尖端提供高压盐水。

2. 发明授权

US5961534A Multi-motion side cutting biopsy sampling device 失效
标题翻译：多运动侧切片活检取样装置
公开(公告)号：US5961534A
公开(公告)日：1999-10-05
申请号：US798564
申请日：1997-02-11
申请人： Michael S. Banik , Donald E. Robinson
发明人： Michael S. Banik , Donald E. Robinson
IPC分类号： A61B10/00 , A61B10/02 , A61B10/06 , A61B17/28 , A61B12/32
CPC分类号： A61B10/06 , A61B2010/0225 , A61B2017/2936 , A61B2017/2939 , A61B2017/2944
摘要： An instrument for obtaining tissue samples from a site deep within the body. The instrument has an elongated proximal portion that is constructed to follow a long, torturous path to the site and a distal end constructed to remove a tissue sample from the body, including tissue specimens, polyps or the like. The instrument is constructed to take multiple biopsy samples without being withdrawn from the body by including a storage space along the axis of the device suitable for storage of multiple, successively taken samples. The instrument includes a side-facing sampling element constructed such that it can be actuated in a first, rotational motion about the device axis to separate a tissue sample from the body and a second, axial motion for disposing the sample axially to facilitate positioning the sample in the storage space.
摘要翻译：用于从身体深处的部位获取组织样本的仪器。该仪器具有细长的近端部分，该近端部分构造成遵循到该部位的长而弯曲的路径，以及构造成从身体移除组织样本的远端，包括组织标本，息肉等。该仪器被构造成采取多个活检样本，而不是通过沿着装置的轴线包括适于存储多个连续采集的样品的存储空间而从身体中排出。仪器包括侧面取样元件，其被构造成使得其能够围绕设备轴线以第一旋转运动来致动，以将组织样本与身体分离，以及第二轴向运动，用于轴向设置样品以便于定位样品在存储空间。

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