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    • 10. 发明授权
    • Compound sea cucumber product, preparation method, and dosage forms thereof
    • 复合海参产品,制备方法及其剂型
    • US08927008B2
    • 2015-01-06
    • US13576972
    • 2011-03-03
    • Jian JiaoJunjie Shao
    • Jian JiaoJunjie Shao
    • A61K9/48A61K36/258A23L1/327A61K35/56
    • A61K36/258A23L17/50A23V2002/00A61K35/616A61K2236/39A61K2300/00A23V2200/25A23V2250/2042
    • A compound sea cucumber product, preparation method thereof and dosage forms thereof are disclosed. A fresh sea cucumber is cut open, the viscus thereof is taken out, and they are well-cleaned respectively and put into an airtight container; at 70˜130° C., gelatinate for 1 min˜20 hours; thereafter freeze-dry till the water content is less than 10 wt %; apply coarse crushing till the fineness reaches 10˜300 mesh; then apply ultra-micro crushing by means of an airflow crusher until the fineness reaches 100˜3000 mesh; lastly apply nanometer crushing by means of high-energy ball grinding mill till the fineness reaches 10˜1000 nm. The nanometer sea cucumber extract is mixed with panax pseudo-ginseng saponins extract at the proportion of 99˜80 wt %:1˜20 wt %. The compound preparation of nanometer sea cucumber and panax pseudo-ginseng saponins can greatly enhance the pharmacological functions of the sea cucumber single preparation or the panax pseudo-ginseng single preparation and eliminate the side effects of the single preparations when used alone. The compound preparation can achieve a better health-care effect than the single preparations and it can be applied for various health-care and medicinal purposes.
    • 公开了一种复合海参产品及其制备方法及其剂型。 将新鲜的海参切开,取出其粘液,分别清洗干净并放入密闭容器中; 在70〜130℃,明胶1分钟〜20小时; 然后冷冻干燥至含水量低于10重量%; 应用粗粉碎至细度达到10〜300目; 然后通过气流破碎机进行超微粉碎,直到细度达到100〜3000目; 最后用高能球磨机进行纳米压碎,直到细度达到10〜1000nm。 将纳米海参提取物与人参皂甙提取物以99〜80重量%:1〜20重量%的比例混合。 纳米海参和人参皂角苷的复合制剂可以大大提高海参单人制剂或人参单人制剂的药理功能,消除单次使用时单一制剂的副作用。 复方制剂可以比单一制剂达到更好的保健效果,可用于各种保健和药用。