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1. 发明授权

US11864567B2 Methods and formulations for reducing bovine emissions 有权
公开(公告)号：US11864567B2
公开(公告)日：2024-01-09
申请号：US17724717
申请日：2022-04-20
申请人： Elanco US Inc.
发明人： Cory T. Herr , John Charles Kube , Jerold Scott Teeter
IPC分类号： A23K20/121 , A23K20/111 , A23K20/132 , A23K20/195 , A23K50/10 , A23K20/184 , A23K10/40 , A23K10/00
CPC分类号： A23K20/111 , A23K10/40 , A23K20/121 , A23K20/132 , A23K20/184 , A23K20/195 , A23K50/10 , A23K10/00 , A23V2002/00 , A23V2002/00 , A23V2200/32
摘要： The present disclosure provides methods and formulations for reducing ammonia and carbon dioxide emissions from a bovine using lubabegron, or a physiologically acceptable salt thereof. The present disclosure also provides bovine feed additives and bovine feed compositions.

2. 发明公开

US20230404107A1 BERBERINE ALKALOIDS IN THE PREVENTION AND/OR TREATMENT OF INTESTINAL DISEASE 审中-公开
公开(公告)号：US20230404107A1
公开(公告)日：2023-12-21
申请号：US16499155
申请日：2018-01-02
申请人： IRP Health Pty Ltd
发明人： David Xiang YU , Zhicheng XIAO , Colin William POUTON , Zhiyong HE
IPC分类号： A23K20/132 , A23K50/75 , A61K31/4375
CPC分类号： A23K20/132 , A23K50/75 , A61K31/4375
摘要： This invention relates to berberine alkaloids, formulations thereof and their use for the prevention and/or treatment of infectious disease, especially disease caused by C. perfringens and Eimeria in animals. The invention also relates to improving the feed conversion ratio in a food producing animal by administering berberine compositions.

3. 发明申请

US20210329946A1 BERBERINE ALKALOID FORMULATIONS IN THE PREVENTION AND/OR TREATMENT OF INFECTIOUS DISEASE 有权
公开(公告)号：US20210329946A1
公开(公告)日：2021-10-28
申请号：US16499163
申请日：2018-03-28
申请人： IRP Health Pty Ltd
发明人： David Xiang YU , Zhicheng XIAO , Colin William POUTON , Zhiyong HE
IPC分类号： A23K20/132 , A23K50/75 , A61K31/4375 , A61P31/04 , A61K9/00 , A23K50/30
摘要： This invention relates to berberine alkaloids, formulations thereof, and their use in the prevention and/or treatment of infectious disease in animals, particularly Lawsonia infection. In particular, the invention relates to berberine alkaloids, formulations thereof, and their application as antimicrobial agents in the prevention and/or treatment of infectious disease including bacterial, viral, parasitic or fungal infections, and for improving feed conversion ratio in food-producing animals. Also described is the use of berberine alkaloids as feed preservatives, added to feed compositions, and used in combination with further agents suitable for treating infectious disease.

4. 发明授权

US10889547B2 Method for the purification of ethoxyquin 有权
公开(公告)号：US10889547B2
公开(公告)日：2021-01-12
申请号：US16311206
申请日：2017-06-22
申请人： BASF SE
发明人： Sumana Roy , Andreas Keller , Wolfgang Siegel , Michael Joedecke , Martin Haubner
IPC分类号： C07D215/20 , B01D3/14 , A23K20/132 , A23L3/3526 , B01D3/10 , B01J19/30
摘要： The present invention relates to a process for purifying ethoxyquin by distillation, to high-purity ethoxyquin obtainable by means of distillative purification and to the use thereof, particularly as additive in foodstuffs and feedstuffs.

5. 发明授权

US10064909B2 Compositions and methods for chronic use of a weight-gaining compound 有权
公开(公告)号：US10064909B2
公开(公告)日：2018-09-04
申请号：US15601240
申请日：2017-05-22
申请人： Aratana Therapeutics, Inc.
发明人： Linda Rhodes , Marie-Paul Lachaud , Bill Zollers , Ernst Heinen
IPC分类号： A61K38/05 , G01N33/74 , A23K50/40 , A23K20/111 , A23K20/132 , A23K20/137 , A23K50/20 , A23K50/10 , A23K50/30 , A23K20/184
摘要： Provided herein is a method of binding growth hormone secretagogue receptors in one or more companion animals or livestock to stimulate hunger independent of release of growth hormone. The method can provide administering a therapeutically effective amount of a capromorelin-containing composition to a companion animal or livestock in need thereof for a period of at least 30 days. Optionally, one or more flavoring agents or flavor-masking agents can be added to the capromorelin-containing composition to enhance or mask the flavoring of the composition for the companion animal or livestock.

6. 发明申请

US20180153203A1 (5R)-(ß-D-GLUCOPYRANOSYLOXY)-1,5-DIHYDRO-2H-PYRROL-2-ONE AS UMAMI MOLECULE 审中-公开
公开(公告)号：US20180153203A1
公开(公告)日：2018-06-07
申请号：US15580473
申请日：2016-06-22
申请人： NESTEC S.A.
发明人： Silke Schopp , Maria Monteiro de Araujo Silva
IPC分类号： A23L27/00 , A23L27/20 , A23L23/10 , A23K20/121 , A23K20/132
CPC分类号： A23L27/88 , A23K20/121 , A23K20/132 , A23K20/137 , A23K50/40 , A23L23/10 , A23L27/2056 , A23V2002/00 , A23V2200/15
摘要： The present invention relates to the use of (5R)-(β-D-glucopyranosyloxy)-1,5-dihydro-2H-pyrrol-2-one for umami taste and/or flavor enhancing of a food product.

7. 发明申请

US20170281712A1 COMPOSITIONS AND METHODS FOR CHRONIC USE OF A WEIGHT-GAINING COMPOUND 审中-公开
公开(公告)号：US20170281712A1
公开(公告)日：2017-10-05
申请号：US15601240
申请日：2017-05-22
申请人： Aratana Therapeutics, Inc.
发明人： Linda Rhodes , Marie-Paul Lachaud , Bill Zollers , Ernst Heinen
IPC分类号： A61K38/05 , A23K20/184 , A23K20/111 , A23K50/40 , A23K20/137 , A23K50/20 , A23K50/10 , A23K50/30 , G01N33/74 , A23K20/132
CPC分类号： A61K38/05 , A23K20/111 , A23K20/132 , A23K20/137 , A23K20/184 , A23K50/10 , A23K50/20 , A23K50/30 , A23K50/40 , G01N33/74 , G01N33/743 , G01N2333/61 , G01N2333/65 , G01N2800/52
摘要： Provided herein is a method of binding growth hormone secretagogue receptors in one or more companion animals or livestock to stimulate hunger independent of release of growth hormone. The method can provide administering a therapeutically effective amount of a capromorelin-containing composition to a companion animal or livestock in need thereof for a period of at least 30 days. Optionally, one or more flavoring agents or flavor-masking agents can be added to the capromorelin-containing composition to enhance or mask the flavoring of the composition for the companion animal or livestock.

8. 发明授权

US4863939A Heteroarylethylamine as production promoters in livestock 失效
标题翻译：杂环三乙胺作为家畜生产促进剂
公开(公告)号：US4863939A
公开(公告)日：1989-09-05
申请号：US80284
申请日：1987-07-30
申请人： Hans Lindel , Werner Hallenbach , Friedrich Berschauer , Anno de Jong , Martin Scheer
发明人： Hans Lindel , Werner Hallenbach , Friedrich Berschauer , Anno de Jong , Martin Scheer
IPC分类号： C07D213/84 , A23K20/132 , A61K31/44 , A61K31/4402 , A61K31/4412 , A61K31/4418 , A61P15/00 , C07D213/36 , C07D213/38 , C07D213/61 , C07D213/70 , C07D213/72 , C07D213/73 , C07D213/74 , C07D213/75 , C07D213/79 , C07D213/81
CPC分类号： C07D213/73 , A23K20/132 , C07D213/38 , C07D213/61
摘要： The growth of livestock is promoted by the new compounds of the formula ##STR1## in which R.sup.1 represents hydrogen, alkyl, halogen, halogenoalkyl, hydroxyl, cyano, alkoxycarbonyl, aminocarbonyl, mono- and dialkylaminocarbonyl, alkoxy, halogenoalkoxy, halogenoalkylthio or NHSO.sub.2 -alkyl,R.sup.2 represents hydrogen, hydroxyl, alkoxy or the --NR.sup.11 R.sup.12 radical,R.sup.3 represents the radicals mentioned in the case of R.sup.1R.sup.4 represents hydroxyl, acyloxy or alkoxy,R.sup.5 represents hydrogen or alkyl,R.sup.6 represents hydrogen or alkyl,R.sup.7 represents hydrogen or alkyl,R.sup.8 represents hydrogen or alkyl,X represents C.sub.1 -C.sub.10 -alkylene or a direct bond,Y represents oxygen or a direct bond,R.sup.9 represents hydrogen, C.sub.1 -C.sub.10 -alkyl which is optionally substituted by hydroxyl, alkoxy, acyloxy or the --NR.sup.13 R.sup.14 radical, or represents the COR.sup.15 radical or the O--Z--R.sup.16 radical,Z represents C.sub.1 -C.sub.10 -alkylene, C.sub.1 -C.sub.10 -alkenylene or C.sub.1 -C.sub.10 -alkinylene,R.sup.10 represents hydrogen, halogen, alkyl, alkoxy, hydroxyl or the COR.sup.15 radical,R.sup.11 represents hydrogen or alkyl,R.sup.12 represents hydrogen, alkyl, halogenoalkyl or acyl,R.sup.13 represents hydrogen, optionally substituted alkyl or optionally substituted aryl,R.sup.14 represents the radicals mentioned in the case of R.sup.13,R.sup.15 represents hydroxyl, alkoxy or the NR.sup.13 R.sup.14 radical, andR.sup.16 represents hydroxyl, alkoxy, acyloxy, the NR.sup.13 R.sup.14 radical or the COR.sup.15 radical,and the physiologically acceptable salts and N-oxides thereof. Several new intermediates are also disclosed.
摘要翻译：新型化合物“IMAGE”促进了家畜的生长，其中R1代表氢，烷基，卤素，卤代烷基，羟基，氰基，烷氧基羰基，氨基羰基，一烷基氨基羰基和二烷基氨基羰基，烷氧基，卤代烷氧基，卤代烷硫基或NHSO2-烷基，R 2表示氢，羟基，烷氧基或-NR 11 R 12基团，R 3表示在R 4表示羟基，酰氧基或烷氧基的情况下提及的基团，R 5表示氢或烷基，R 6表示氢或烷基，R 7表示氢或烷基， R8表示氢或烷基，X表示C1-C10-亚烷基或直接键，Y表示氧或直接键，R9表示氢，任选被羟基，烷氧基，酰氧基或-NR13R14基团取代的C1-C10-烷基，或表示COR15基团或OZ-R16基团，Z表示C1-C10-亚烷基，C1-C10亚烯基或C1-C10亚烯基，R10表示氢，卤素，烷基，烷氧基，羟基或COR15基，R11 代理人 R12表示氢，烷基，卤代烷基或酰基，R13表示氢，任选取代的烷基或任选取代的芳基，R 14表示在R 13的情况下提及的基团，R 15表示羟基，烷氧基或NR 13 R 14基，R 16 表示羟基，烷氧基，酰氧基，NR 13 R 14基或COR 15基，及其生理上可接受的盐和N-氧化物。还披露了几个新的中间体。

9. 发明授权

US11344047B2 Methods and formulations for reducing bovine emissions 有权
公开(公告)号：US11344047B2
公开(公告)日：2022-05-31
申请号：US15514876
申请日：2016-10-03
申请人： Elanco US Inc.
发明人： Cory T. Herr , John Charles Kube , Jerold Scott Teeter
IPC分类号： A23K50/10 , A23K20/111 , A23K20/121 , A23K20/132 , A23K20/195 , A23K20/184 , A23K10/40 , A23K10/00
摘要： The present disclosure provides methods and formulations for reducing ammonia and carbon dioxide emissions from a bovine using lubabegron, or a physiologically acceptable salt thereof. The present disclosure also provides bovine feed additives and bovine feed compositions.

10. 发明申请

US20220118064A1 MULTI-SUPPLEMENT COMPOSITIONS 有权
公开(公告)号：US20220118064A1
公开(公告)日：2022-04-21
申请号：US17562330
申请日：2021-12-27
申请人： Melaleuca, Inc.
发明人： Alexander B. Rabovsky , Begonia Yeeman Ho , Stephanie Y. Nielson , Nasser A. Fredj , Subhendu Nayak , Erin A. Stone
IPC分类号： A61K38/48 , A23L33/15 , A23L33/10 , A61K31/702 , A23L33/175 , A23L33/115 , A61K45/06 , A23L33/11 , A23L33/105 , A23K20/121 , A61K33/42 , A23L33/29 , A23L33/135 , A23K20/24 , A23K20/168 , A23K20/142 , A23K20/189 , A23K20/132 , A23K20/174 , A23K20/10 , A23K10/18 , A23K20/111 , A23K20/158 , A23K20/126 , A23K20/163 , A61K31/10 , A61K31/12 , A61K31/122 , A61K31/202 , A61K31/205 , A61K31/355 , A61K31/385 , A61K31/435 , A61K31/593 , A61K31/685 , A61K31/7004 , A61K31/726 , A61K33/06 , A61K35/60 , A61K35/745 , A61K35/747 , A61K36/16 , A61K36/68 , A61K36/74 , A61K36/81 , A61K36/82 , A61K36/87 , A61K36/9068
摘要： This document provides dietary supplement compositions. For example, multi-supplement compositions having combinations of dietary supplement formulations useful for human or animal consumption are provided.

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