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1. 发明授权

US07578982B1 Radioisotope TI-201 production process 有权
标题翻译：放射性同位素TI-201生产工艺
公开(公告)号：US07578982B1
公开(公告)日：2009-08-25
申请号：US11500931
申请日：2006-08-09
申请人： Wuu-Jyh Lin , Ting-Shien Duh , Ying-Ming Tsai , Sun-Rong Huang , Chien-Hsin Lu , Mao-Hsung Chang , Jenn-Tzong Chen
发明人： Wuu-Jyh Lin , Ting-Shien Duh , Ying-Ming Tsai , Sun-Rong Huang , Chien-Hsin Lu , Mao-Hsung Chang , Jenn-Tzong Chen
IPC分类号： C01F3/00 , C01F13/00 , C01F15/00
CPC分类号： G21G1/10 , G21G1/001 , G21G2001/0078
摘要： A radioisotope TI-201 is produced. The process includes electroplating, irradiating, dissolving, precipitating, ion exchanging, decaying and filtering. The TI-201 obtained is a liquid having a high purity.
摘要翻译：生产放射性同位素TI-201。该方法包括电镀，照射，溶解，沉淀，离子交换，腐蚀和过滤。获得的TI-201是具有高纯度的液体。

2. 发明授权

US07138643B2 Method and apparatus for separating ions of metallic elements in aqueous solution 失效
标题翻译：在水溶液中分离金属元素的离子的方法和装置
公开(公告)号：US07138643B2
公开(公告)日：2006-11-21
申请号：US10762990
申请日：2004-01-22
申请人： Robert E. Lewis , Fu-Min Su , Timothy A. Lane , Keith R. Olewine , Peter S. Holton
发明人： Robert E. Lewis , Fu-Min Su , Timothy A. Lane , Keith R. Olewine , Peter S. Holton
IPC分类号： G21G1/02
CPC分类号： G21G1/0005 , G21G2001/0078 , G21G2001/0094
摘要： Methods and apparatus for separating ions of metallic elements are provided. Preferred methods utilize a hydrophobic chelating extractant, such as an organophosphorus compound, adsorbed onto carbon or graphite fibers in the form of felt. Also described is a new thallium-201 generator that comprises a column containing an acidic organophosphorus extractant adsorbed on carbon or graphite fibers, and a yttrium-90 generator system comprised of two extraction columns designed to selectively absorb yttrium-90 at different pH, to enable the separation of yttrium-90 from strontium-90. The two columns are connected in series for stepwise separation. The yttrium-90 product is freed from residual strontium-90 and metal contaminants and can be eluted from the second column with dilute acid, acetate buffer, water or saline for labeling biological targeted molecules. The new generator system provides rapid and efficient separation of yttrium-90 and is amenable to both scale-up and automation. Also described is a new 99mTc generator that comprises a column containing an acidic organophosphorus extractant adsorbed on carbon or graphite fibers designed to selectively absorb 99Mo at a selected pH, to enable the separation of 99mTc from 99Mo.
摘要翻译：提供了分离金属元素离子的方法和装置。优选的方法利用以毡的形式吸附到碳或石墨纤维上的疏水螯合萃取剂，例如有机磷化合物。还描述了一种新的铊-201发生器，其包含吸附在碳或石墨纤维上的酸性有机磷萃取剂的柱，以及由两个提取塔组成的钇-90发生器系统，其设计成在不同pH下选择性吸收钇-90，以使得钇-90与锶-90分离。两列串联连接以进行逐步分离。钇-90产物不含残留的锶-90和金属污染物，并可用稀酸，乙酸盐缓冲液，水或盐水从第二柱洗脱，用于标记生物靶向分子。新型发电机系统可快速有效地分离钇-90，并适应放大和自动化。还描述了一种新的99m Tc发生器，其包括吸附在碳或石墨纤维上的酸性有机磷萃取剂的柱，其设计成在选定的pH下选择性吸收99％的Mo，以使得能够从99％Mo分离99m Tc。

3. 发明申请

US20090211917A1 RADIOISOTOPE T1-201 PRODUCTION PROCESS 有权
标题翻译：放射科技T1-201生产工艺
公开(公告)号：US20090211917A1
公开(公告)日：2009-08-27
申请号：US11500931
申请日：2006-08-09
申请人： Wuu-Jyh Lin , Ting-Shien Duh , Ying-Ming Tsai , Sun-Rong Huang , Chien-Hsin Lu , Mao-Hsung Chang , Jenn-Tzong Chen
发明人： Wuu-Jyh Lin , Ting-Shien Duh , Ying-Ming Tsai , Sun-Rong Huang , Chien-Hsin Lu , Mao-Hsung Chang , Jenn-Tzong Chen
IPC分类号： C25B1/24
CPC分类号： G21G1/10 , G21G1/001 , G21G2001/0078
摘要： A radioisotope Tl-201 is produced. The process includes electroplating, irradiating, dissolving precipitating, ion exchanging, decaying and filtering. The Tl-201 obtained is a liquid having a high purity.
摘要翻译：生产放射性同位素Tl-201。该方法包括电镀，照射，溶解沉淀，离子交换，腐蚀和过滤。得到的T1-201是纯度高的液体。

4. 发明申请

US20040164025A1 Method and apparatus for separating ions of metallic elements in aqueous solution 失效
标题翻译：在水溶液中分离金属元素的离子的方法和装置
公开(公告)号：US20040164025A1
公开(公告)日：2004-08-26
申请号：US10762990
申请日：2004-01-22
发明人： Robert E. Lewis , Fu-Min Su , Timothy A. Lane , Keith R. Olewine , Peter S. Holton
IPC分类号： C22B060/00 , B01D015/00
CPC分类号： G21G1/0005 , G21G2001/0078 , G21G2001/0094
摘要： Methods and apparatus for separating ions of metallic elements are provided. Preferred methods utilize a hydrophobic chelating extractant, such as an organophosphorus compound, adsorbed onto carbon or graphite fibers in the form of felt. Also described is a new thallium-201 generator that comprises a column containing an acidic organophosphorus extractant adsorbed on carbon or graphite fibers, and a yttrium-90 generator system comprised of two extraction columns designed to selectively absorb yttrium-90 at different pH, to enable the separation of yttrium-90 from strontium-90. The two columns are connected in series for stepwise separation. The yttrium-90 product is freed from residual strontium-90 and metal contaminants and can be eluted from the second column with dilute acid, acetate buffer, water or saline for labeling biological targeted molecules. The new generator system provides rapid and efficient separation of yttrium-90 and is amenable to both scale-up and automation. Also described is a new 99mTc generator that comprises a column containing an acidic organophosphorus extractant adsorbed on carbon or graphite fibers designed to selectively absorb 99Mo at a selected pH, to enable the separation of 99mTc from 99Mo.
摘要翻译：提供了分离金属元素离子的方法和装置。优选的方法利用以毡的形式吸附到碳或石墨纤维上的疏水螯合萃取剂，例如有机磷化合物。还描述了一种新的铊-201发生器，其包含吸附在碳或石墨纤维上的酸性有机磷萃取剂的柱，以及由两个提取塔组成的钇-90发生器系统，其设计成在不同pH下选择性吸收钇-90，以使得钇-90与锶-90分离。两列串联连接以进行逐步分离。钇-90产物不含残留的锶-90和金属污染物，并可用稀酸，乙酸盐缓冲液，水或盐水从第二柱洗脱，用于标记生物靶向分子。新型发电机系统可快速有效地分离钇-90，并适应放大和自动化。还描述了一种新的99m Tc生成器，其包括吸附在碳或石墨纤维上的酸性有机磷萃取剂的柱，其设计为在选定的pH下选择性吸收99Ma，以使99m Tc从99 >莫。

5. 发明申请

US20030152502A1 Method and apparatus for separating ions of metallic elements in aqueous solution 审中-公开
标题翻译：在水溶液中分离金属元素的离子的方法和装置
公开(公告)号：US20030152502A1
公开(公告)日：2003-08-14
申请号：US10321333
申请日：2002-12-17
发明人： Robert E. Lewis , Fu-Min Su , Timothy A. Lane , Keith R. Olewine , Peter S. Holton
IPC分类号： B01D015/00
CPC分类号： G21G1/0005 , G21G2001/0078 , G21G2001/0094
摘要： Methods and apparatus for separating ions of metallic elements are provided. Preferred methods utilize a hydrophobic chelating extractant, such as an organophosphorus compound, adsorbed onto carbon or graphite fibers in the form of felt. Also described is a new thallium-201 generator that comprises a column containing an acidic organophosphorus extractant adsorbed on carbon or graphite fibers, and a yttrium-90 generator system comprised of two extraction columns designed to selectively absorb yttrium-90 at different pH, to enable the separation of yttrium-90 from strontium-90. The two columns are connected in series for stepwise separation. The yttrium-90 product is freed from residual strontium-90 and metal contaminants and can be eluted from the second column with dilute acid, acetate buffer, water or saline for labeling biological targeted molecules. The new generator system provides rapid and efficient separation of yttrium-90 and is amenable to both scale-up and automation.
摘要翻译：提供了分离金属元素离子的方法和装置。优选的方法利用以毡的形式吸附到碳或石墨纤维上的疏水螯合萃取剂，例如有机磷化合物。还描述了一种新的铊-201发生器，其包含吸附在碳或石墨纤维上的酸性有机磷萃取剂的柱，以及由两个提取塔组成的钇-90发生器系统，其设计成在不同pH下选择性吸收钇-90，以使得钇-90与锶-90分离。两列串联连接以进行逐步分离。钇-90产物不含残留的锶-90和金属污染物，并可用稀酸，乙酸盐缓冲液，水或盐水从第二柱洗脱，用于标记生物靶向分子。新型发电机系统可快速有效地分离钇-90，并适应放大和自动化。

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