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1. 发明申请

US20180207264A1 PORCINE IMMUNE MODULATION MODEL 审中-公开
公开(公告)号：US20180207264A1
公开(公告)日：2018-07-26
申请号：US15875606
申请日：2018-01-19
申请人： Government of the United States as Represented by the Secretary of the Air Force
发明人： Thomas Shaak , Suizhao Wang , Joseph Harre
IPC分类号： A61K39/39 , A61K31/568 , A61K31/573 , A61K9/00 , A61K9/127
CPC分类号： A61K9/1271 , A61B10/02 , A61B17/32053 , A61B2017/00707 , A61K9/0019 , A61K31/565 , A61K31/568 , A61K31/573 , A61K39/39 , A61K47/10 , A61K47/24 , A61K2300/00 , A61M1/0088 , A61P35/00 , G09B23/306 , G09B23/34
摘要： A method of modulating an immune response. The method includes administering a treatment comprising delta 5-androsten-3B, 17B-diol, delta 5-androsten-3B, 7B, 17B-triol, or both.

2. 发明申请

US20180055570A1 Low-Resistance Anatomical Tissue Model 审中-公开
公开(公告)号：US20180055570A1
公开(公告)日：2018-03-01
申请号：US15682733
申请日：2017-08-22
申请人： Virtamed AG
发明人： Carolyn O'BRIEN , Kelly WETTENGEL
IPC分类号： A61B34/10 , G09B23/30 , G09B23/34
CPC分类号： A61B34/10 , G09B23/285 , G09B23/30 , G09B23/306 , G09B23/34
摘要： Anatomy mannequins, models and medical simulation systems described herein may facilitate various medical procedure training by rendering a realistic passive haptic touch when the end user manipulates the anatomy model with a handheld tool. An anatomy tissue model may comprise at least one fabric layer arranged over at least one foam layer to replicate the low-friction, elasticity and hardness of a living body anatomy tissue, such as the vagina wall, without requiring the use of lubricant in the medical simulation training procedure. The anatomy tissue model may be attached as an insert to a body structure model. A diversity of anatomy tissue models may be adapted with different fabric layer and/or foam layer designs, each design corresponding to a different haptic touch, so they can be interchanged in a medical training simulator system to realistically replicate different medical training scenarios.

3. 发明申请

US20170263158A1 SPINAL INJECTION TRAINER AND METHODS THEREFOR 有权
公开(公告)号：US20170263158A1
公开(公告)日：2017-09-14
申请号：US15608652
申请日：2017-05-30
申请人： BIOTRAS HOLDINGS, LLC
发明人： Johnny Wayne East , Brandon Knutson , Edwin V. East, JR.
IPC分类号： G09B23/28 , G09B23/30 , G09B23/34 , A61B17/16
CPC分类号： G09B23/285 , A61B5/4566 , A61B17/1671 , B29C45/14795 , G09B23/28 , G09B23/30 , G09B23/306 , G09B23/34
摘要： A model for anatomical training includes a clear thermoplastic elastomer matrix formed with at least one contoured surface that simulates at least a portion of a human body. The visibly clear thermoplastic elastomer matrix provides visible needle tracks upon needle penetration that may be fused closed upon heating the thermoplastic elastomer matrix. The model includes at least a portion of a vertebral column with a synthetic spinal sheath passing through a portion of the vertebral column, the synthetic spinal sheath providing tactile feedback upon needle penetration that simulates the tactile feedback of a needle penetrating a natural human spinal sheath.

4. 发明申请

US20170238533A1 HEART-LUNG PREPARATION AND METHOD OF USE 审中-公开
公开(公告)号：US20170238533A1
公开(公告)日：2017-08-24
申请号：US15592343
申请日：2017-05-11
申请人： Medtronic, Inc.
发明人： Paul A. IAIZZO , Timothy G. LASKE , Michael D. EGGEN , Ryan P. GOFF , Brian HOWARD
IPC分类号： A01N1/02 , G09B23/30
CPC分类号： A01N1/0247 , G09B23/303 , G09B23/306
摘要： An isolated heart or heart-lung preparation in which essentially normal pumping activity of all four chambers of the heart is preserved, allowing for the use of the preparation in conjunction with investigations of electrode leads, catheters, ablation methods, cardiac implants and other medical devices intended to be used in or on a beating heart. The system can be designed to be used within a Magnetic Resonance Imaging (MRI) unit or a X-ray computed tomography (CT) scanner. The preparation may also be employed to investigate heart and lung functions, in the presence or absence of such medical devices. In order to allow comparative imaging visualizations of either or simultaneously the heart and/or lung structures and devices located within the chambers of the heart or vessels or bronchi within the lungs, a clear perfusate such as a modified Krebs buffer solution with oxygenation is circulated through all four chambers of the heart and thus the coronary and/or pulmonary vasculatures. A ventilator with intubation tube can be used to inflate/deflate the lungs and/or provide oxygen to the isolated organs. The preparation and recordings of the preparation may be used in conjunction with the design, development and evaluation of devices for use in or on the heart and/or lungs, as well as for use as an investigational and teaching aid to assist physicians and students in understanding the operation of the cardiopulmonary system.

5. 发明申请

US20160329000A1 MODULAR STAGED REALITY SIMULATOR 有权
公开(公告)号：US20160329000A1
公开(公告)日：2016-11-10
申请号：US15148317
申请日：2016-05-06
申请人： The University of North Carolina at Chapel Hill
发明人： Richard H. Feins , W. Andrew Grubbs , Alexander McLain Grubbs , Matthew M. Dedmon
IPC分类号： G09B23/30
CPC分类号： G09B23/306 , G09B19/00 , G09B23/30 , G09B23/303
摘要： This invention is directed to a modular staged simulator and a process of simulating medical trauma and maladies for the purpose of training or certifying individuals including medical professionals. More specifically, this disclosure relates to ex vivo training exercises as opposed to traditional forms of training using intact cadavers, in vivo surgery on animal subjects; and supervised apprenticeship performing surgery on human subjects with trauma or maladies under the watch of a skilled medical practitioner.

6. 发明申请

US20160314717A1 TELEROBOTIC SURGERY SYSTEM FOR REMOTE SURGEON TRAINING USING ROBOTIC SURGERY STATION COUPLED TO REMOTE SURGEON TRAINEE AND INSTRUCTOR STATIONS AND ASSOCIATED METHODS 审中-公开
标题翻译：用于远程手术训练的机器人手术系统，使用机器人手术站与远程训练员和指导员站联合进行远程训练和相关方法
公开(公告)号：US20160314717A1
公开(公告)日：2016-10-27
申请号：US15150635
申请日：2016-05-10
申请人： KINDHEART, INC.
发明人： W. Andrew GRUBBS
IPC分类号： G09B23/30 , G09B23/32 , A61B34/35
CPC分类号： G09B23/306 , A61B34/35 , A61B34/37 , A61B90/361 , A61B2017/00216 , A61B2034/254 , A61B2090/371 , G09B5/14 , G09B23/32 , H04L67/12
摘要： A telerobotic surgery system for remote surgeon training may include a robotic surgery station at a first location in a first structure at a first geographic point. Harvested animated animal tissue is at the robotic surgery station and includes harvested animal tissue, and at least one animating device coupled thereto. A remote surgeon trainee station at a second location in a second structure at a second geographic point is remote from the first geographic point. A remote surgeon instructor station may also be included. A communications network couples the stations so that a trainee surgeon at the remote surgeon trainee station is able to remotely train by performing surgery on the harvested animated animal tissue at said robotic surgery station, and while an instructor surgeon at the remote surgeon instructor station is able to remotely instruct the trainee surgeon by also performing surgery.
摘要翻译：用于远程外科医生训练的远程外科手术系统可以包括在第一地理点处的第一结构中的第一位置的机器人手术台。收获的动物动物组织在机器人手术台处，并且包括收获的动物组织，和至少一个耦合到其上的动画装置。在第二地理点处的第二结构中的第二位置处的远程外科医生实习站远离第一地理点。还可以包括远程外科医生指导台。通信网络耦合站，使得在远程外科医生实习站的实习外科医生能够通过在所述机器人手术站对所获取的动物动物组织进行手术来远程训练，并且在远程外科医生指导站的教导外科医生能够通过执行手术远程指导实习医生。

7. 发明授权

US09472121B2 Portable laparoscopic trainer 有权
标题翻译：便携式腹腔镜教练
公开(公告)号：US09472121B2
公开(公告)日：2016-10-18
申请号：US14270664
申请日：2014-05-06
申请人： Applied Medical Resources Corporation
发明人： Boun Pravong , Kennii Pravongviengkham , Lee Cohen , Charles C. Hart , Vivek Sikri , Zoran Falkenstein , Richard W Conklin , Eduardo Bolanos , Adam Hoke , Jacob J. Filek , Michael Palermo
IPC分类号： G09B23/30 , G09B23/28
CPC分类号： G09B23/285 , G09B5/02 , G09B23/30 , G09B23/306 , G09B23/34
摘要： A portable surgical training device is provided. The trainer includes a top cover spaced apart from a base to form a simulated body cavity for locating model organs that are substantially obscured from the field of view of the user. The top cover includes a video display, fixed insertion ports and interchangeable inserts containing simulated tissue layers. The training device has open sides for demonstrating and training lateral surgical techniques including a simulated or live tissue colon attached to a support leg for simulating transanal minimally invasive surgery. A training endoscope with an adjustable focal length for use with the trainer and, in particular, with optical trocars is disclosed. The surgical trainer can be angled and is well suited for training laparoscopic surgery techniques and demonstrating surgical instruments.
摘要翻译：提供便携式外科手术训练装置。训练器包括与基座间隔开的顶盖，以形成模拟体腔，用于定位从使用者视野基本遮蔽的模型器官。顶盖包括视频显示器，固定插入端口和包含模拟组织层的可互换插入件。训练装置具有展示和训练横向手术技术的开放性，包括连接到支撑腿的模拟或活组织结肠，用于模拟经肛门微创手术。公开了一种具有可调节焦距的训练内窥镜，用于训练者，特别是与光学套针。手术训练器可以成角度，非常适合于培养腹腔镜手术技术和展示手术器械。

8. 发明申请

US20150024362A1 SURGICAL SIMULATION ASSEMBLY 有权
标题翻译：手术模拟装置
公开(公告)号：US20150024362A1
公开(公告)日：2015-01-22
申请号：US14340265
申请日：2014-07-24
申请人： KindHeart, Inc.
发明人： Richard H. Feins , Tom Birchard , W. Andrew Grubbs , Don Aikin , Daniel C. Fuccella
IPC分类号： G09B23/30
CPC分类号： G09B23/303 , A61G13/08 , G09B23/30 , G09B23/306
摘要： A surgical simulation assembly is provided for simulating realistic surgery on animal organs or human cadavers. The surgical simulation assembly comprises a generally flat tray having a central indentation for receiving an organ, at least one drainage aperture and at least one indented trough extending from the central indentation for receiving at least one tube. The tray is assembled with a simulator heart and lungs prepped for connection to a variable speed double action air pump assembly that creates both positive pressure and a vacuum on the heart to simulate a beating heart. The tray is supported on a basket having a lower containment portion for containing fluid waste collected during the simulated surgery. The basket is elevated by risers over a base designed to support the assembly.
摘要翻译：提供了一种手术模拟组件，用于模拟动物器官或人体尸体的现实手术。手术模拟组件包括具有用于接纳器官的中心凹陷，至少一个排水孔和从中心凹槽延伸的至少一个凹槽的大致平坦的托盘，用于容纳至少一个管。托盘组装有模拟器心脏和肺，准备连接到变速双动气泵组件，其在心脏上产生正压和真空以模拟跳动心脏。托盘支撑在具有下容纳部分的篮子上，用于容纳在模拟手术期间收集的流体废物。篮子由提升器升高到设计用于支撑组件的基座上。

9. 发明申请

US20140335496A1 HUMAN CONDUCTING AIRWAY MODEL COMPRISING MULTIPLE FLUIDIC PATHWAYS 审中-公开
标题翻译：包含多个流体路径的人造航空模型
公开(公告)号：US20140335496A1
公开(公告)日：2014-11-13
申请号：US14362419
申请日：2012-12-04
申请人： Research Triangle Institute , The University of North Carolina at Chapel Hill
发明人： Sonia Grego , Kristin Hedgepath Gilchrist , Scott H. Randell
IPC分类号： G09B23/30
CPC分类号： G09B23/306 , C12M21/08 , C12M23/16 , C12M25/02 , C12M25/14 , C12M35/08 , G01N33/5088
摘要： A multicellular fluidic enhanced airway model system of the conducting airways as a tool for the evaluation of biological threats and medical countermeasures is provided. The airway model system can include a first chamber having an inlet and an outlet and containing epithelial cells; a second chamber having an inlet and an outlet and containing an extracellular matrix, wherein the second chamber is separated from the first chamber by a porous membrane; and a third chamber having an inlet and an outlet, wherein the third chamber is separated from the second chamber by a porous membrane, and wherein the airway tissue model system is configured to provide a separate fluidic pathway through each of said first, second, and third chambers. A method of analyzing tissue response to an agent via an airway tissue model system is also provided.
摘要翻译：提供了导航气道的多细胞流体强化气道模型系统作为评估生物威胁和医疗对策的工具。气道模型系统可以包括具有入口和出口并包含上皮细胞的第一腔室; 具有入口和出口并且包含细胞外基质的第二腔室，其中所述第二腔室通过多孔膜与所述第一腔室分离; 以及具有入口和出口的第三腔室，其中所述第三腔室通过多孔膜与所述第二腔室分离，并且其中所述气道组织模型系统构造成提供通过所述第一，第二和第第三室。还提供了一种通过气道组织模型系统分析对试剂的组织反应的方法。

10. 发明授权

US08764452B2 Portable laparoscopic trainer 有权
标题翻译：便携式腹腔镜教练
公开(公告)号：US08764452B2
公开(公告)日：2014-07-01
申请号：US13248449
申请日：2011-09-29
申请人： Boun Pravong , Kennii Pravongviengkham , Lee Cohen , Charles C. Hart , Vivek Sikri , Zoran Falkenstein , Rick Conklin , Eduardo Bolanos , Adam Hoke , Jacob J. Filek , Michael Palermo
发明人： Boun Pravong , Kennii Pravongviengkham , Lee Cohen , Charles C. Hart , Vivek Sikri , Zoran Falkenstein , Rick Conklin , Eduardo Bolanos , Adam Hoke , Jacob J. Filek , Michael Palermo
IPC分类号： G09B23/28 , G09B23/30
CPC分类号： G09B23/285 , G09B5/02 , G09B23/30 , G09B23/306 , G09B23/34
摘要： A portable surgical training device is provided. The trainer includes a top cover spaced apart from a base to form a simulated body cavity for locating model organs that are substantially obscured from the field of view of the user. The top cover includes a video display, fixed insertion ports and interchangeable inserts containing simulated tissue layers. The training device has open sides for demonstrating and training lateral surgical techniques including a simulated or live tissue colon attached to a support leg for simulating transanal minimally invasive surgery. A training endoscope with an adjustable focal length for use with the trainer and, in particular, with optical trocars is disclosed. The surgical trainer can be angled and is well suited for training laparoscopic surgery techniques and demonstrating surgical instruments.
摘要翻译：提供便携式外科手术训练装置。训练器包括与基座间隔开的顶盖，以形成模拟体腔，用于定位从使用者视野基本遮蔽的模型器官。顶盖包括视频显示器，固定插入端口和包含模拟组织层的可互换插入件。训练装置具有展示和训练横向手术技术的开放性，包括连接到支撑腿的模拟或活组织结肠，用于模拟经肛门微创手术。公开了一种具有可调节焦距的训练内窥镜，用于训练者，特别是与光学套针。手术训练器可以成角度，非常适合于培养腹腔镜手术技术和展示手术器械。

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