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    • 8. 发明申请
    • Optical Analysis System With Background Signal Compensation
    • 具有背景信号补偿的光学分析系统
    • US20070291251A1
    • 2007-12-20
    • US11574181
    • 2005-08-24
    • Wouter RensenBernardus Leonardus BakkerMichael Van Beek
    • Wouter RensenBernardus Leonardus BakkerMichael Van Beek
    • G01N33/48G01N21/00G06F19/00
    • G01J3/30G01J3/02G01J3/0229G01J3/32G01J3/44
    • The invention provides an optical analysis system for efficient compensation of spectroscopic broadband back-ground, such as spectroscopic fluorescence background or background signals that are due to the dark current of a detector. The optical analysis system effectively provides multivariate optical analysis of a spectroscopic signal. It provides wavelength selective detection of various spectral components that are indicative of a superposition of spectroscopic peaks or bands and their broadband background. Additionally, the optical analysis system is adapted to acquire spectral components that predominantly correspond to the broadband background of the spectroscopic peaks or bands. Wavelength selective selection of various spectral components is performed on the basis of reconfigurable multivariate optical elements or on the basis of a position displacement of a spatial optical transmission mask.
    • 本发明提供了一种用于有效补偿光谱宽带背景的光学分析系统,例如由于检测器的暗电流引起的分光荧光背景或背景信号。 光学分析系统有效地提供了光谱信号的多变量光学分析。 它提供各种光谱分量的波长选择性检测,这些光谱分量指示光谱峰或带的叠加及其宽带背景。 此外,光学分析系统适于获取主要对应于光谱峰或带的宽带背景的光谱分量。 基于可重构多变量光学元件或者基于空间光学透射掩模的位置位移来执行各种光谱分量的波长选择性选择。
    • 9. 发明授权
    • Multivariate spectroscopy with optical computation
    • 多光谱与光学计算
    • US6078389A
    • 2000-06-20
    • US376542
    • 1999-08-18
    • Mark S. Zetter
    • Mark S. Zetter
    • G01J3/02G01J3/12G01J3/30G01J3/42G01J3/51G01N21/59G01J3/00
    • G01J3/02G01J3/0218G01J3/30G01J3/42G01J3/51G01N21/59G01J3/12
    • A method is presented to perform accurate property measurements using spectroscopic measurements at multiple wavelengths using nondispersed radiation with one, or sometimes two, detectors sensing all the requisite wavelengths simultaneously and calculating the value of the property by optical means. The heart of our invention is the utilization of an optical device opaque everywhere but at the finite and limited number of wavelengths where the transmittance measurements are being made, and whose transmittance at the measuring wavelengths is proportional to the coefficient for that wavelength in a predictive equation for the property value. The process which is our invention passes nondispersed light through a sample, with the transmitted light being led onto an optical device passing only the measuring wavelengths onto a detector. The optical device transmittances at the measuring wavelengths are proportional to the coefficients for those wavelengths, so that the total light passing through the optical device is actually proportional to the value of the property being measured. Our method leads to substantial reduction in instrument costs through simplified design and a reduction in components, with concomitant increased ease of use, and the elimination of the need for ancillary computational means.
    • 提出了一种使用具有一个或有时两个检测器同时检测所有必需波长的非分散辐射在多个波长上进行光谱测量的精确性质测量的方法,并通过光学方法计算该性质的值。 我们发明的核心在于使用不透明的光学装置,但是在有限和有限数量的波长处进行透射率测量,并且其在测量波长处的透射率与预测方程中该波长的系数成比例 为物业价值。 本发明的方法使非分散的光通过样品,其中透射的光被引导到仅将测量波长传递到检测器上的光学装置上。 在测量波长处的光学器件透射率与这些波长的系数成比例,使得通过光学器件的总光线实际上与被测量的性质的值成正比。 我们的方法通过简化设计和减少部件,同时提高易用性,消除对辅助计算手段的需求,从而大大降低了仪器成本。