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1. 发明授权

US08506526B2 Seal structures for wet/dry automatic injectors 有权
标题翻译：湿/干自动注射器的密封结构
公开(公告)号：US08506526B2
公开(公告)日：2013-08-13
申请号：US13468421
申请日：2012-05-10
申请人： Steven M. Griffiths , Robert L. Hill
发明人： Steven M. Griffiths , Robert L. Hill
IPC分类号： A61M37/00
CPC分类号： A61M5/31596 , A61M5/19 , A61M5/2033 , A61M5/2066 , A61M5/284 , A61M5/286 , A61M5/3145 , A61M5/31513 , A61M5/3202 , A61M5/3293 , A61M5/34 , A61M5/343 , A61M5/348 , A61M2005/206 , A61M2005/2073 , A61M2005/287 , A61M2005/3106 , A61M2005/3131 , A61M2005/3132 , A61M2202/064 , A61M2205/7536 , A61M2205/7545
摘要： An automatic injection device including a housing, a chamber with a first compartment and a second compartment, and a seal structure between the compartments. The seal structure is initially in a sealing condition that seals the first compartment from the second compartment, where the seal includes a plug and an outer sealing member. The plug is slidably movable within the outer sealing member to convert the seal structure from the sealing condition to a mixing condition by opening a path between the first compartment and the second compartment. The automatic injection device also includes a needle assembly and an activation assembly. Activation of the activation assembly causes (1) pressurization of the first compartment, (2) the seal structure to convert from the sealing condition to the mixing condition, and (3) the first and second medicament components to be mixed and forced through the needle assembly.
摘要翻译：一种自动注射装置，包括壳体，具有第一隔室的腔室和第二隔室，以及隔室之间的密封结构。密封结构最初处于将第一隔室与第二隔室密封的密封状态，其中密封件包括塞子和外密封件。塞子可在外部密封件内滑动移动，以通过打开第一隔室和第二隔室之间的路径将密封结构从密封状态转换成混合状态。自动注射装置还包括针组件和激活组件。激活组件的激活导致（1）第一隔室的加压，（2）密封结构从密封条件转化为混合状态，以及（3）要混合并强制通过针的第一和第二药物成分部件。

2. 发明申请

US20120220930A1 Seal Structures For Wet/Dry Automatic Injectors 有权
标题翻译：湿/干自动注射器的密封结构
公开(公告)号：US20120220930A1
公开(公告)日：2012-08-30
申请号：US13468421
申请日：2012-05-10
申请人： Steven M. GRIFFITHS , Robert L. Hill
发明人： Steven M. GRIFFITHS , Robert L. Hill
IPC分类号： A61M5/31
CPC分类号： A61M5/31596 , A61M5/19 , A61M5/2033 , A61M5/2066 , A61M5/284 , A61M5/286 , A61M5/3145 , A61M5/31513 , A61M5/3202 , A61M5/3293 , A61M5/34 , A61M5/343 , A61M5/348 , A61M2005/206 , A61M2005/2073 , A61M2005/287 , A61M2005/3106 , A61M2005/3131 , A61M2005/3132 , A61M2202/064 , A61M2205/7536 , A61M2205/7545
摘要： An automatic injection device including a housing, a chamber with a first compartment and a second compartment, and a seal structure between the compartments. The seal structure is initially in a sealing condition that seals the first compartment from the second compartment, where the seal includes a plug and an outer sealing member. The plug is slidably movable within the outer sealing member to convert the seal structure from the sealing condition to a mixing condition by opening a path between the first compartment and the second compartment. The automatic injection device also includes a needle assembly and an activation assembly. Activation of the activation assembly causes (1) pressurization of the first compartment, (2) the seal structure to convert from the sealing condition to the mixing condition, and (3) the first and second medicament components to be mixed and forced through the needle assembly.
摘要翻译：一种自动注射装置，包括壳体，具有第一隔室的腔室和第二隔室，以及隔室之间的密封结构。密封结构最初处于将第一隔室与第二隔室密封的密封状态，其中密封件包括塞子和外密封件。塞子可在外部密封件内滑动移动，以通过打开第一隔室和第二隔室之间的路径将密封结构从密封状态转换成混合状态。自动注射装置还包括针组件和激活组件。激活组件的激活导致（1）第一隔室的加压，（2）密封结构从密封条件转化为混合状态，以及（3）要混合并强制通过针的第一和第二药物成分部件。

3. 发明申请

US20100228190A1 SEAL STRUCTURES FOR WET/DRY AUTOMATIC INJECTORS 有权
标题翻译：湿/干自动注射器密封结构
公开(公告)号：US20100228190A1
公开(公告)日：2010-09-09
申请号：US12784595
申请日：2010-05-21
申请人： Steven M. Griffiths , Robert L. Hill
发明人： Steven M. Griffiths , Robert L. Hill
IPC分类号： A61M5/31
CPC分类号： A61M5/31596 , A61M5/19 , A61M5/2033 , A61M5/2066 , A61M5/284 , A61M5/286 , A61M5/3145 , A61M5/31513 , A61M5/3202 , A61M5/3293 , A61M5/34 , A61M5/343 , A61M5/348 , A61M2005/206 , A61M2005/2073 , A61M2005/287 , A61M2005/3106 , A61M2005/3131 , A61M2005/3132 , A61M2202/064 , A61M2205/7536 , A61M2205/7545
摘要： An automatic medicament injector has a first compartment for a first medicament component and a second compartment for a second medicament component. The two compartments are separated by a seal structure that converts from a sealing condition to a mixing condition when the device is activated. The seal structure has a plug that opens a flow path through the seal structure to allow the second medicament component to mix with the first medicament component in the first compartment when the seal structure is in the mixing condition.
摘要翻译：自动药物注射器具有用于第一药物组分的第一隔室和用于第二药物组分的第二隔室。两个隔室由密封结构分开，当设备被激活时，该密封结构从密封条件转变为混合状态。密封结构具有塞子，该塞子打开通过密封结构的流动路径，以便当密封结构处于混合状态时允许第二药物组分与第一隔室中的第一药物组分混合。

4. 发明申请

US20020123717A1 DISPOSABLE NEEDLE-FREE INJECTION APPARATUS AND METHOD 失效
标题翻译：不需要的无针注射装置和方法
公开(公告)号：US20020123717A1
公开(公告)日：2002-09-05
申请号：US09799787
申请日：2001-03-05
申请人： Bioject Medical Technologies Inc.
发明人： Sergio Landau
IPC分类号： A61M005/00
CPC分类号： A61M5/30 , A61M5/1782 , A61M5/2053 , A61M5/3007 , A61M2005/287 , A61M2005/3132
摘要： One form of the invention provides a needle-free injection system including the following components: a nozzle portion having a glass wall defining a drug storage space, and an injection wall defining a drug injection space, the injection wall being coaxial with the glass wall and defining a plurality of drug bypass conduits disposed adjacent a forward end of the drug injection space; an injection orifice defined at the forward end of the injection space; a drug plunger defining a rearward end of the storage space; a drug plug initially disposed between the storage space and the injection space, and being displaceable into the injection space adjacent the bypass conduits; and a pierceable gas cartridge for providing injection power to the drug plunger.
摘要翻译：本发明的一种形式提供了一种无针注射系统，其包括以下部件：具有限定药物储存空间的玻璃壁的喷嘴部分和限定药物注射空间的注射壁，所述注射壁与玻璃壁同轴，限定邻近药物注射空间的前端设置的多个药物旁路导管; 注射孔限定在注射空间的前端; 药剂柱塞，其限定所述存储空间的后端; 最初设置在所述存储空间和所述注入空间之间的药物塞，并且能够邻近所述旁路管道移动到所述注入空间中; 以及用于向药物柱塞提供注射力的可刺穿的气体盒。

5. 发明授权

US5688252A Syringe 失效
标题翻译：注射器
公开(公告)号：US5688252A
公开(公告)日：1997-11-18
申请号：US535915
申请日：1995-09-28
申请人： Terumi Matsuda , Nobuo Tanaka
发明人： Terumi Matsuda , Nobuo Tanaka
IPC分类号： A61M5/28 , A61M5/315 , A61M5/00
CPC分类号： A61M5/2448 , A61M5/284 , A61M5/31511 , A61M2005/287 , A61M5/31515
摘要： A syringe has a tubular body provided at its front end portion with a portion for mounting an injection needle thereon and opens at its rear end portion so as to have a rear end opening. A gasket for sealing the rear end opening of the tubular body is slidably inserted into the tubular body. A plunger rod is detachably coupled with a rear end portion of the gasket through the rear end opening of the tubular body. A male screw is formed at a front end portion of the plunger rod and is circumferentially alternately divided into at least one male screw portion and at least one first recess portion. A female screw is formed on a rear end face of the gasket and is circumferentially alternately divided into at least one female screw portion and at least one second recess portion. A state where the male screw portion and the first recess portion of the male screw are, respectively, fitted into the second recess portion and the female screw portion of the female screw, the male screw is rotated relative to the female screw so as to be brought into engagement with the female screw such that the plunger rod is coupled with the gasket.
摘要翻译：注射器具有在其前端部设置有用于在其上安装注射针的部分的管状体，并在其后端部开口以具有后端开口。用于密封管状体的后端开口的垫圈可滑动地插入到管状体中。柱塞杆通过管状体的后端开口与衬垫的后端部分可拆卸地联接。外螺纹形成在柱塞杆的前端部，并且周向交替地分成至少一个阳螺纹部和至少一个第一凹部。内螺纹形成在垫圈的后端面上，并且周向地交替地分成至少一个内螺纹部分和至少一个第二凹部。外螺纹部和外螺纹的第一凹部分别嵌入第二凹部和内螺纹的内螺纹部的状态，外螺纹相对于内螺纹旋转，与内螺纹接合，使得柱塞杆与垫圈联接。

6. 发明授权

US5273542A Pre-filled syringe with flow valve 失效
标题翻译：带流量阀的预充注射器
公开(公告)号：US5273542A
公开(公告)日：1993-12-28
申请号：US944455
申请日：1992-09-14
申请人： Joseph W. Blake, III
发明人： Joseph W. Blake, III
IPC分类号： A61M5/28 , A61M5/00
CPC分类号： A61M5/286 , A61M2005/287
摘要： The present invention is a hypodermic syringe pre-filled with a volume of a desired solution. A plug member is positioned within the hypodermic syringe in between the pre-filled fluid and the lumen of the syringe's cannula. The presence of the plug member within the hypodermic syringe separates the cannula from the pre-filled fluid thereby leaving the cannula unaffected by the presence of the fluid within the syringe. As the plunger of the hypodermic syringe is engaged, the pressure of the pre-filled fluid is increased. The fluid pressure acts upon the plug member, displacing the plug member when a predetermined fluid pressure is achieved. Once the plug member is displaced, the occlusion between the pre-filled fluid and the cannula is removed and the pre-filled fluid is free to flow through the lumen of the cannula.
摘要翻译：本发明是预先填充一定体积的所需溶液的皮下注射器。插塞构件位于注射器插管的预填充流体和内腔之间的皮下注射器内。插塞构件在皮下注射器内的存在将套管与预填充的流体分开，从而使套管不受注射器内流体的存在的影响。当皮下注射器的柱塞接合时，预填充流体的压力增加。流体压力作用在塞子构件上，当实现预定的流体压力时使塞子构件移位。一旦插塞构件被移动，则预先填充的流体和套管之间的闭合被移除，并且预填充的流体自由地流过插管的内腔。

7. 发明授权

US5125892A Dispenser for storing and mixing several components 失效
标题翻译：用于存储和混合多个组件的分配器
公开(公告)号：US5125892A
公开(公告)日：1992-06-30
申请号：US579299
申请日：1990-08-14
申请人： Arnie Drudik
发明人： Arnie Drudik
IPC分类号： A61M5/28 , A61M5/315
CPC分类号： A61M5/31596 , A61M2005/287 , A61M5/286 , A61M5/31505
摘要： The invention relates to a plural-compartment dispenser for storing and mixing several components at least one of them a liquid, and in particular to a dispenser comprising a barrel, a plunger, a needle or means to connect same, finger grip or means to connect same, a stopper placed in the barrel between the needle and the plunger, said stopper having a hollow dilated central cavity open proximally and distally by apertures, said proximal aperture being releasably sealed by a bounded or fitted pressure activated blow plug.
摘要翻译：本发明涉及一种多室分配器，用于储存和混合多个部件，其中至少一个部件为液体，特别涉及一种分配器，包括筒体，柱塞，针或连接其的装置，手指夹或连接装置相同的是，塞子被放置在针和柱塞之间的筒体中，所述止动器具有通过孔向近端和远端打开的中空扩张的中心腔，所述近端孔通过有界或装配的压力激活的吹塞可释放地密封。

8. 发明授权

US3941128A Fluid dispensing arrangement 失效
标题翻译：流体分配装置
公开(公告)号：US3941128A
公开(公告)日：1976-03-02
申请号：US515966
申请日：1974-10-18
申请人： Brian E. Baldwin
发明人： Brian E. Baldwin
IPC分类号： A61M5/28 , A61M5/32 , A61M5/34 , A61M5/00
CPC分类号： A61M5/286 , A61M5/32 , A61M5/34 , A61M2005/287
摘要： A fluid dispensing arrangement for injecting liquid parenteral drugs or other liquids, including a syringe or cartridge with a needle-hub secured thereto, a plunger in the syringe or cartridge for effecting liquid discharge and injection, and a combination sealing and by-pass valve plug initially in a radially compressed sealing position at the forward end of the cartridge or syringe body or barrel and separating the liquid in the cartridge or syringe body or barrel from the needle-hub assembly, the valve plug being longitudinally forwardly movable to a by-pass discharge position within a by-pass chamber of larger diameter than the normal unrestricted and uncompressed diameter of the plug. The plug has tapered cruciform ends with corresponding circumferentially spaced by-pass grooves formed thereby at its opposite ends to aid in liquid by-pass therepast during liquid discharge or aspirating action.
摘要翻译：一种用于注射液体肠胃外药物或其他液体的流体分配装置，包括固定有针座的注射器或药筒，用于进行液体排出和注射的注射器或药筒中的柱塞，以及组合密封和旁通阀塞最初在药筒或注射器主体或针筒的前端处的径向压缩的密封位置中，将药筒或注射器主体或针筒中的液体与针毂组件分开，阀塞纵向向前移动到旁路在旁路室内的排放位置比直径大于插塞的正常无限制和未压缩直径。塞子具有锥形十字形端部，在其相对端形成相应的周向间隔开的旁路凹槽，以在液体排放或抽吸动作期间帮助液体旁路。

9. 发明授权

US3326215A Two compartment syringe with vapor seal between compartments 失效
标题翻译：两室间注射器，隔室之间具有蒸汽密封
公开(公告)号：US3326215A
公开(公告)日：1967-06-20
申请号：US33074163
申请日：1963-12-16
申请人： SARNOFF
发明人： SARNOFF STANLEY J , BALENGER JOHN W
IPC分类号： A61M5/28 , A61M5/315
CPC分类号： A61M5/284 , A61M5/286 , A61M2005/287 , A61M2005/31598

10. 发明授权

US3240209A Needle cap 失效
标题翻译：针帽
公开(公告)号：US3240209A
公开(公告)日：1966-03-15
申请号：US37879564
申请日：1964-06-29
申请人： HYPODERMIC NEEDLE VALVE CORP
发明人： OGLE ROBERT W
IPC分类号： A61M5/31 , A61M5/32
CPC分类号： A61M5/32 , A61M5/31 , A61M2005/287

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