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1. 发明申请

US20090137941A1 METHOD AND APPARATUS FOR ACOUSTICALLY ENHANCED REMOVAL OF BUBBLES FROM A FLUID 审中-公开
标题翻译：用于从流体中有效地去除泡沫的方法和装置
公开(公告)号：US20090137941A1
公开(公告)日：2009-05-28
申请号：US12129985
申请日：2008-05-30
申请人： John E. Lynch , Christopher S. Domack
发明人： John E. Lynch , Christopher S. Domack
IPC分类号： A61M1/36 , B01D19/00
CPC分类号： A61M1/3627 , A61M1/3626 , A61M1/363 , A61M1/3666 , A61M2205/3606 , B01D19/0078
摘要： A vessel for removing bubbles from a fluid is provided. The vessel includes a fluid inlet port for receiving the fluid, and a bubble outlet port for removing bubbles in the fluid from the vessel. An ultrasonic transducer is mounted in the vessel and transmits an ultrasonic beam through the received fluid to move bubbles in the fluid towards the bubble outlet port. A fluid outlet port outputs the fluid insonified by the ultrasonic beam. An ultrasonic reflector mounted near the bubble outlet port reflects the ultrasonic beam away from the fluid outlet port to reduce or prevent reflection of the ultrasonic beam off an interior surface in the vessel directed towards the fluid outlet port.
摘要翻译：提供了用于从流体中除去气泡的容器。容器包括用于接收流体的流体入口和用于从容器中除去流体中的气泡的气泡出口。超声换能器安装在容器中，并将超声波束穿过接收的流体，以将流体中的气泡移向气泡出口。流体出口输出由超声波束加强的液体。安装在气泡出口附近的超声波反射器将超声波束从流体出口端口反射离开，以减少或防止超声波束从指向流体出口的容器内表面的反射。

2. 发明申请

US20090105628A1 EXTRACORPOREAL ULTRASONIC MEDICAL DEVICE 审中-公开
标题翻译：超声波超声医疗器械
公开(公告)号：US20090105628A1
公开(公告)日：2009-04-23
申请号：US12345486
申请日：2008-12-29
申请人： Simcha MILO
发明人： Simcha MILO
IPC分类号： A61N7/00 , B01D17/12 , B01D19/00 , A61M1/36 , B01D24/40 , B01D35/01
CPC分类号： A61M1/3627 , A61B8/481 , A61B17/22012 , A61B2017/22009 , A61M1/363 , B01D19/0078 , B01D19/0084
摘要： Ultrasonic devices for preventing microbubbles and/or microparticles from reaching the brain during a PCI or cardiovascular surgery. Devices 27 and 77 are designed for implantation in the chest cavity and operate in combination with needle vents or other vent systems for removing diverted microbubbles. Systems 77 and 83 are designed for noninvasive employment. Devices 57 and 87 are particularly designed to prevent microbubbles from reaching the great origins of the carotid arteries and/or for diverting bubbles that might reach the vicinity and otherwise pass through. Improved devices 11 and 94 separate microbubbles from a flowing bloodstream and produce a cleansed stream.
摘要翻译：用于在PCI或心血管手术期间防止微泡和/或微粒到达脑的超声波装置。设备27和77设计用于植入胸腔，并与排气口或其他排气系统组合操作，用于去除转移的微泡。系统77和83设计用于无创工作。装置57和87被特别设计用于防止微泡到达颈动脉的大起点和/或用于转移可能到达附近或以其他方式通过的气泡。改进的装置11和94将微泡与流动的血液分离并产生清洁的流。

3. 发明授权

US5334136A System for treating blood processed in a cardiopulmonary bypass machine and ultrasound filtration apparatus useful therein 失效
标题翻译：用于治疗在体外循环机中处理的血液的系统和其中有用的超声过滤装置
公开(公告)号：US5334136A
公开(公告)日：1994-08-02
申请号：US467444
申请日：1990-01-19
申请人： Karl Schwarz , Richard S. Meltzer , Charles C. Church
发明人： Karl Schwarz , Richard S. Meltzer , Charles C. Church
IPC分类号： A61M1/36 , B01D19/00 , A61M1/30
CPC分类号： B01D19/0078 , A61M1/3627 , A61M1/363
摘要： A system for reducing post-cardiopulmonary bypass encephalopathy due to microembolization of the brain of a patient with gaseous microbubbles (less than 40 microns in diameter) occurring during open-heart surgery using a cardiopulmonary bypass machine by passing a stream of blood from the patient through an ultrasonic traveling wave which propagates across the stream without reflection and sweeps the blood clean of the microbubbles without inducing blood cell trauma. The blood passes through a chamber between an input port and a filtrate exit port. An ultrasonic beam is projected so that a pressure maximum of the main lobe of the beam is centered at the filtrate exit port. The microbubbles are carried by the traveling wave to a waste exit port in the chamber downstream of the input port. To prevent establishment of resonance conditions, reflections and traveling waves the chamber may be submerged in a liquid bath and a body of acoustic absorbent material disposed at an end of the chamber opposite to the end into which the ultrasonic beam is projected.
摘要翻译：一种系统，用于通过使来自患者的血液流通过心肺旁路机器的患者的脑部微栓塞（小于直径小于40微米）而在心脏外科手术中发生的体外循环脑病系统，超声波行波，其在没有反射的情况下传播，并扫描微泡的血液清洁而不引起血细胞损伤。血液通过输入口和滤液出口之间的腔室。投射超声波束，使得光束的主瓣的最大压力在滤液出口处居中。微波通过行波携带到输入端口下游的室中的废物出口。为了防止共振条件的建立，反射和行波，室可以浸没在液体槽中，并且吸声材料体设置在与突出超声波束的端部相反的端部处的吸声材料体。

4. 发明授权

US10016552B2 Method of ultrasonic degassing of liquids for dialysis 有权
公开(公告)号：US10016552B2
公开(公告)日：2018-07-10
申请号：US14784118
申请日：2014-03-27
申请人： Fresenius Medical Care Deutschland GmbH
发明人： Michael Koch
IPC分类号： B01D19/00 , A61M1/16 , C02F1/20 , A61M1/36 , C02F1/36 , C02F1/44 , C02F103/02
CPC分类号： A61M1/1658 , A61M1/363 , A61M2205/123 , B01D19/0063 , B01D19/0078 , C02F1/20 , C02F1/36 , C02F1/44 , C02F2103/026
摘要： A device for degassing liquids, in particular liquids used in dialysis, has a degassing unit that includes an ultrasonic unit. Liquids to be degassed are treated in the degassing unit by ultrasound from the ultrasonic unit. Degassed liquids are discharged from the degassing unit through a hollow channel in the ultrasonic unit, and are available for further use.

5. 发明申请

US20110245750A1 METHOD AND APPARATUS FOR ACOUSTICALLY ENHANCED REMOVAL OF BUBBLES FROM A FLUID 审中-公开
标题翻译：用于从流体中有效地去除泡沫的方法和装置
公开(公告)号：US20110245750A1
公开(公告)日：2011-10-06
申请号：US13063547
申请日：2009-09-08
申请人： John E Lynch , Christopher S. Domack , Bill B. Hefner, JR.
发明人： John E Lynch , Christopher S. Domack , Bill B. Hefner, JR.
IPC分类号： A61M1/36 , B01D19/00
CPC分类号： A61M1/3627 , A61M1/3626 , A61M1/363 , A61M2205/3375 , A61M2205/3606 , A61M2206/16 , B01D19/0057 , B01D19/0078
摘要： A vessel for removing bubbles from a fluid is provided. The vessel includes a fluid inlet port for receiving the fluid and a bubble outlet for removing bubbles in the fluid from the vessel. One or more ultrasonic transducers transmit one or more ultrasonic beams through the received fluid to move bubbles in the fluid towards the bubble outlet. A fluid outlet port outputs the fluid insonified by the one or more ultrasonic beams. A conduit structure conveys the one or more ultrasonic beams through the vessel in a first direction towards the air outlet. An interface prevents reflection of one or more ultrasonic beams in a direction generally opposite the first direction.
摘要翻译：提供了用于从流体中除去气泡的容器。容器包括用于接收流体的流体入口和用于从容器中除去流体中的气泡的气泡出口。一个或多个超声换能器通过所接收的流体传送一个或多个超声波束，以将流体中的气泡移向气泡出口。流体出口端口输出被一个或多个超声波束加强的流体。导管结构将一个或多个超声波束沿第一方向传送通过容器朝向空气出口。接口防止一个或多个超声波束在与第一方向大致相反的方向上的反射。

6. 发明授权

US07470363B2 Separation device for removing microbubbles 失效
标题翻译：用于除去微泡的分离装置
公开(公告)号：US07470363B2
公开(公告)日：2008-12-30
申请号：US11245583
申请日：2005-10-07
申请人： Simcha Milo
发明人： Simcha Milo
IPC分类号： B01D19/00
CPC分类号： A61M1/3627 , A61B8/481 , A61B17/22012 , A61B2017/22009 , A61M1/363 , B01D19/0078 , B01D19/0084
摘要： Ultrasonic devices for preventing microbubbles and/or microparticles from reaching the brain during a PCI or cardiovascular surgery. Devices 27 and 77 are designed for implantation in the chest cavity and operate in combination with needle vents or other vent systems for removing diverted microbubbles. Systems 77 and 83 are designed for noninvasive employment. Devices 57 and 87 are particularly designed to prevent microbubbles from reaching the great origins of the carotid arteries and/or for diverting bubbles that might reach the vicinity and otherwise pass through. Improved devices 11 and 94 separate microbubbles from a flowing bloodstream and produce a cleansed stream.
摘要翻译：用于在PCI或心血管手术期间防止微泡和/或微粒到达脑的超声波装置。设备27和77设计用于植入胸腔，并与排气口或其他排气系统组合操作，用于去除转移的微泡。系统77和83设计用于无创工作。装置57和87被特别设计用于防止微泡到达颈动脉的大起点和/或用于转移可能到达附近或以其他方式通过的气泡。改进的装置11和94将微泡与流动的血液分离并产生清洁的流。

7. 发明申请

US20070045188A1 Ultrasonic Material Removal System for Cardiopulmonary Bypass and Other Applications 失效
标题翻译：超声波材料去除系统用于心肺旁路及其他应用
公开(公告)号：US20070045188A1
公开(公告)日：2007-03-01
申请号：US11463121
申请日：2006-08-08
申请人： Jared Blanton
发明人： Jared Blanton
IPC分类号： A01N1/02 , B01D69/04
CPC分类号： B01D19/0094 , A61M1/3627 , A61M1/363
摘要： Devices, systems, and methods manipulate target materials within fluids, and may be useful for removing microbubbles and other materials from blood. Ultrasound or acoustic filtering waves may be directed across a flow of blood, and differences in density between the target microbubbles and the blood may enhance separation by driving the lighter matter upward for removal from the blood stream. A disposable acoustically transmissive conduit can replaceably engage an ultrasound transmitter to facilitate sterilization. Exemplary conduits have elongate lumen cross-sections and an axial path resembling a portion of a Mobius strip.
摘要翻译：设备，系统和方法操纵流体内的目标材料，并且可用于从血液中除去微泡和其他材料。超声波或声波过滤波可以被引导穿过血流，并且目标微泡和血液之间的密度差可以通过向上驱动较轻的物质来提高分离，从而从血流中除去。一次性透声导管可以替代地接合超声波发射器以促进灭菌。示例性管道具有细长的内腔横截面和类似于Mobius条的一部分的轴向路径。

8. 发明申请

US20130175226A1 ACOUSTIC SEPARATORS 审中-公开
标题翻译：声音分离器
公开(公告)号：US20130175226A1
公开(公告)日：2013-07-11
申请号：US13805551
申请日：2011-06-24
申请人： Constantin Coussios , Yiannis Ventikos , Giuliana Trippa , David Taggart
发明人： Constantin Coussios , Yiannis Ventikos , Giuliana Trippa , David Taggart
IPC分类号： B01D21/28
CPC分类号： B01D21/28 , A61M1/363 , A61M1/3633 , A61M1/3678 , A61M1/3693 , B01D21/283 , B01D2221/10 , Y10T29/49826
摘要： An acoustic separator comprises: two parallel chamber walls defining a separation chamber therebetween, each chamber wall defining one side of the chamber; inlet means through which fluid can flow into the chamber; and outlet means through which fluid can flow out of the chamber. One of the chamber walls includes a transducer arranged to transmit pressure waves across the chamber towards the other of the chamber walls which in turn is arranged to reflect the pressure waves to set up a standing wave in the chamber. The outlet means defines an opening in one of the sides of the chamber.
摘要翻译：声分离器包括：两个平行的室壁，在其间限定分隔室，每个室壁限定室的一侧; 流体可以通过该入口装置流入腔室; 以及流体可以通过其流出室的出口装置。腔壁之一包括一个换能器，其被布置成将压力波穿过腔室朝向腔室壁中的另一个，这又被布置成反射压力波，以在腔室中建立驻波。出口装置在腔室的一个侧面中限定开口。

9. 发明授权

US07842123B2 Extraction of gas from infused liquid 失效
标题翻译：从输液中提取气体
公开(公告)号：US07842123B2
公开(公告)日：2010-11-30
申请号：US12429106
申请日：2009-04-23
申请人： Ehud Milo , Simcha Milo
发明人： Ehud Milo , Simcha Milo
IPC分类号： B01D19/00
CPC分类号： A61M1/3627 , A61M1/363 , B01D19/0057
摘要： Apparatus (20) for removing gas bubbles from a liquid to be infused to a patient wherein a gas trap (42) is located at the upper end of a vertical column (38, 40, 40a) having a lower inlet (44) and an upper outlet (56). A bracket (39) supports the column above the patient, and a bubble-separator (46, 39a, 47, 66, 63), positioned between the inlet and the outlet, causes gas bubbles to move toward the column axis as they rise so that they are captured in the gas trap (42). Liquid to be de-gasified is supplied from a vertical level above the column outlet and is delivered through the side outlet (56) to the patient below.
摘要翻译：用于从要输注给患者的液体中除去气泡的装置（20），其中气体收集器（42）位于具有下入口（44）的垂直柱（38,40,40a）的上端，并且上部出口（56）。支架（39）支撑患者上方的柱，并且位于入口和出口之间的气泡分离器（46,39a，47,66,63）在其上升时使气泡朝向柱轴移动它们被捕获在气阱（42）中。要脱气的液体从柱出口上方的垂直水平供应并且通过侧出口（56）输送到下面的患者。

10. 发明申请

US20100152625A1 EXTRACORPOREAL ULTRASONIC MEDICAL DEVICE 审中-公开
标题翻译：超声波超声医疗器械
公开(公告)号：US20100152625A1
公开(公告)日：2010-06-17
申请号：US12709488
申请日：2010-02-21
申请人： Simcha MILO
发明人： Simcha MILO
IPC分类号： A61N7/00 , A61M37/00
CPC分类号： A61M1/3627 , A61B8/481 , A61B17/22012 , A61B2017/22009 , A61M1/363 , B01D19/0078 , B01D19/0084
摘要： Ultrasonic devices for preventing microbubbles and/or microparticles from reaching the brain during a PCI or cardiovascular surgery. Devices 27 and 77 are designed for implantation in the chest cavity and operate in combination with needle vents or other vent systems for removing diverted microbubbles. Systems 77 and 83 are designed for noninvasive employment. Devices 57 and 87 are particularly designed to prevent microbubbles from reaching the great origins of the carotid arteries and/or for diverting bubbles that might reach the vicinity and otherwise pass through. Improved devices 11 and 94 separate microbubbles from a flowing bloodstream and produce a cleansed stream.
摘要翻译：用于在PCI或心血管手术期间防止微泡和/或微粒到达脑的超声波装置。设备27和77设计用于植入胸腔，并与排气口或其他排气系统组合操作，用于去除转移的微泡。系统77和83设计用于无创工作。装置57和87被特别设计用于防止微泡到达颈动脉的大起点和/或用于转移可能到达附近或以其他方式通过的气泡。改进的装置11和94将微泡与流动的血液分离并产生清洁的流。

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