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1. 发明授权

US10500312B2 Bioactive porous bone graft compositions with collagen 有权
公开(公告)号：US10500312B2
公开(公告)日：2019-12-10
申请号：US14543862
申请日：2014-11-17
申请人： PROSIDYAN, INC.
发明人： Charanpreet S. Bagga , Steve B. Jung , Hyun W. Bae
IPC分类号： A61L27/56 , A61L27/54 , A61L27/34
CPC分类号： A61L27/56 , A61L27/34 , A61L27/54 , A61L2300/10 , A61L2300/102 , A61L2300/104 , A61L2300/112 , A61L2300/404 , A61L2300/412
摘要： Bioactive porous bone graft implants in various forms suitable for use in bone tissue regeneration and/or repair, as well as methods of use are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may be contained in polymer for enhanced clinical results and better handling.

2. 发明授权

US09655990B2 Polymer based hydrogel 有权
公开(公告)号：US09655990B2
公开(公告)日：2017-05-23
申请号：US14783081
申请日：2014-04-08
申请人： YEDITEPE UNIVERSITESI
发明人： Fikrettin Sahin , Selami Demirci , Aysegul Dogan
IPC分类号： A61L26/00 , A61K9/00 , A61K47/32 , A61L15/26 , A61L15/44 , A61L15/46 , A61K47/34 , A61K8/04 , A61K8/19 , A61K8/84 , A61Q17/00 , A61Q19/08 , C08K3/38
CPC分类号： A61L26/0019 , A61K8/042 , A61K8/19 , A61K8/84 , A61K8/90 , A61K9/0014 , A61K47/32 , A61K47/34 , A61L15/26 , A61L15/44 , A61L15/46 , A61L26/0004 , A61L26/0066 , A61L26/008 , A61L2300/10 , A61L2300/404 , A61L2300/412 , A61Q17/005 , A61Q19/08 , C08K3/38 , C08K2003/387 , C08L71/02
摘要： The present invention relates to an anti-aging antimicrobial wound healing polymer based hydrogel. In the study of the present invention, a wound healing gel formulation is developed by combining poloxamer polymers and boron component at adequate concentrations in a carbopol based gel. The said gel exhibits fast action on the damaged area and prevents scar formation.

3. 发明申请

US20170027660A1 TAGGED SURGICAL INSTRUMENTS AND METHODS THEREFOR 审中-公开
标题翻译：标记的手术仪器及其方法
公开(公告)号：US20170027660A1
公开(公告)日：2017-02-02
申请号：US15303286
申请日：2015-10-04
申请人： COVIDIEN LP
发明人： William A. Blair
IPC分类号： A61B90/00 , A61B17/06 , A61B8/08 , A61B90/90
CPC分类号： A61B90/39 , A61B8/481 , A61B17/06004 , A61B90/90 , A61B2017/00526 , A61B2090/3929 , A61B2090/3933 , A61B2090/3983 , A61L17/04 , A61L17/14 , A61L2300/10 , A61L2300/44 , C08L25/06
摘要： Provided herein is a tag comprising an imaging sphere suspended within a matrix. In some embodiments, the matrix comprises a polymer. In some embodiments, the matrix comprises an adhesive polymer. In some embodiments, the matrix comprises a shelf-stable polymer. In some embodiments, the matrix comprises an epoxy. In some embodiments, the adhesive polymer comprises cyanoacrylate. In some embodiments, the imaging sphere comprises a cavity loaded with an imaging agent surrounded by a shell. In some embodiments, the imaging agent exhibits echogenic properties. Further provided is a method for preparing an imaging sphere comprising: depositing organic or inorganic material onto a bead surface to form a sphere with a solid core; removing the solid core by solvent extraction or calcination to form a hollow sphere; and loading the hollow sphere with an imaging agent.
摘要翻译：本文提供的是包括悬浮在基质内的成像球的标签。在一些实施方案中，基质包含聚合物。在一些实施方案中，基质包含粘合剂聚合物。在一些实施方案中，基质包含储存稳定的聚合物。在一些实施方案中，基质包含环氧树脂。在一些实施方案中，粘合剂聚合物包含氰基丙烯酸酯。在一些实施例中，成像球包括加载有由壳包围的成像剂的空腔。在一些实施方案中，成像剂显示回声特性。还提供了一种用于制备成像球的方法，包括：将有机或无机材料沉积到珠粒表面上以形成具有实芯的球体; 通过溶剂萃取或煅烧去除固体核心以形成中空球体; 并用成像剂装载中空球体。

4. 发明授权

US09474831B2 Systems, devices, and methods including implantable devices with anti-microbial properties 有权
标题翻译：系统，装置和方法，包括具有抗微生物特性的可植入装置
公开(公告)号：US09474831B2
公开(公告)日：2016-10-25
申请号：US12931926
申请日：2011-02-14
申请人： Edward S. Boyden , Roy P. Diaz , Roderick A. Hyde , Jordin T. Kare , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
发明人： Edward S. Boyden , Roy P. Diaz , Roderick A. Hyde , Jordin T. Kare , Elizabeth A. Sweeney , Lowell L. Wood, Jr.
IPC分类号： A61L2/00 , A61L29/08 , A61L2/232 , A61L2/24 , A61L2/26 , A61L27/54 , A61L31/08 , A61L17/14 , A61L27/28 , A61L27/30 , A61L29/00 , A61L29/16 , B82Y5/00 , B82Y30/00 , A61L2/08 , A61L2/14 , B82Y40/00
CPC分类号： A61L2/24 , A61L2/0011 , A61L2/08 , A61L2/14 , A61L2/232 , A61L2/26 , A61L17/145 , A61L27/28 , A61L27/306 , A61L27/54 , A61L29/00 , A61L29/08 , A61L29/16 , A61L31/024 , A61L31/026 , A61L31/08 , A61L31/14 , A61L31/16 , A61L2202/14 , A61L2300/10 , A61L2300/108 , A61L2300/404 , A61L2300/606 , A61M25/0045 , A61M27/006 , B82Y5/00 , B82Y30/00 , B82Y40/00
摘要： Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.
摘要翻译：描述了用于提供被配置为例如监测，治疗或预防微生物生长或粘附于植入物的主动控制植入物的系统，装置，方法和组合物。

5. 发明申请

US20160213806A1 SOLID DRESSING FOR TREATING WOUNDED TISSUE 审中-公开
公开(公告)号：US20160213806A1
公开(公告)日：2016-07-28
申请号：US15088438
申请日：2016-04-01
申请人： STB, Ltd.
发明人： Martin MacPhee , Dawson Beall
IPC分类号： A61L15/44 , A61L15/22 , A61L15/32 , A61L15/58 , A61L15/64 , A61L15/38
CPC分类号： A61L15/64 , A61F13/00012 , A61F13/00017 , A61F13/00021 , A61F13/00029 , A61F13/00034 , A61F13/00063 , A61F13/00068 , A61F13/00991 , A61F13/02 , A61F13/0226 , A61F13/0246 , A61F2013/00106 , A61F2013/00174 , A61F2013/00472 , A61F2013/00536 , A61F2013/0054 , A61F2013/0091 , A61F2013/00931 , A61K38/363 , A61K38/4833 , A61L15/18 , A61L15/225 , A61L15/26 , A61L15/28 , A61L15/32 , A61L15/325 , A61L15/38 , A61L15/44 , A61L15/58 , A61L26/0042 , A61L26/0052 , A61L26/0066 , A61L26/009 , A61L2300/10 , A61L2300/252 , A61L2300/254 , A61L2300/418 , A61L2300/604 , A61L2300/606 , A61L2300/608 , A61L2400/04 , C12Y304/21005 , C08L89/00
摘要： Disclosed are solid dressings for treated wounded tissue in mammalian patients, such as a human, comprising a haemostatic layer consisting essentially of a fibrinogen component and thrombin, wherein the thrombin is present in an amount between 0.250 Units/mg of fibrinogen component and 0.062 Units/mg of fibrinogen component. Also disclosed are methods for treating wounded tissue.

6. 发明申请

US20160175098A1 Solid Forms for Tissue Repair 审中-公开
标题翻译：用于组织修复的固体形式
公开(公告)号：US20160175098A1
公开(公告)日：2016-06-23
申请号：US14978510
申请日：2015-12-22
申请人： CARTIHEAL (2009) LTD.
发明人： Nir ALTSCHULER , Razi VAGO
IPC分类号： A61F2/30 , A61L27/54 , A61L27/38 , A61L27/34
CPC分类号： A61F2/30756 , A61F2/28 , A61F2/30 , A61F2/4618 , A61F2002/30205 , A61F2002/30224 , A61F2002/30299 , A61F2002/30795 , A61F2002/30878 , A61F2002/30891 , A61F2002/4627 , A61F2230/0067 , A61F2230/0069 , A61F2230/0093 , A61F2310/00341 , A61K33/10 , A61K35/12 , A61K38/00 , A61K45/06 , A61L27/025 , A61L27/34 , A61L27/3604 , A61L27/38 , A61L27/3834 , A61L27/427 , A61L27/446 , A61L27/54 , A61L27/56 , A61L2300/10 , A61L2300/406 , A61L2300/414 , A61L2300/426 , A61L2300/606 , A61L2300/64 , A61L2430/02 , A61L2430/06 , C08L5/08
摘要： This invention provides coral-based scaffolds for cartilage repair, and instruments for insertion and utilization of same within a site of cartilage repair.
摘要翻译：本发明提供了用于软骨修复的基于珊瑚的支架，以及用于在软骨修复部位内插入和使用其的仪器。

7. 发明申请

US20150056262A1 SOLID FORMS FOR TISSUE REPAIR 审中-公开
标题翻译：固定形式用于组织修复
公开(公告)号：US20150056262A1
公开(公告)日：2015-02-26
申请号：US14321491
申请日：2014-07-01
申请人： Cartiheal (2009) Ltd.
发明人： Nir Altschuler , Razi Vago
IPC分类号： A61L27/02 , A61K45/06 , A61L27/34 , A61L27/54 , A61K33/10 , A61L27/38
CPC分类号： A61F2/30756 , A61F2/28 , A61F2/30 , A61F2/4618 , A61F2002/30205 , A61F2002/30224 , A61F2002/30299 , A61F2002/30795 , A61F2002/30878 , A61F2002/30891 , A61F2002/4627 , A61F2230/0067 , A61F2230/0069 , A61F2230/0093 , A61F2310/00341 , A61K33/10 , A61K35/12 , A61K38/00 , A61K45/06 , A61L27/025 , A61L27/34 , A61L27/3604 , A61L27/38 , A61L27/3834 , A61L27/427 , A61L27/446 , A61L27/54 , A61L27/56 , A61L2300/10 , A61L2300/406 , A61L2300/414 , A61L2300/426 , A61L2300/606 , A61L2300/64 , A61L2430/02 , A61L2430/06 , C08L5/08
摘要： This invention provides coral-based scaffolds for cartilage repair, and instruments for insertion and utilization of same within a site of cartilage repair.
摘要翻译：本发明提供了用于软骨修复的基于珊瑚的支架，以及用于在软骨修复部位内插入和使用其的仪器。

8. 发明授权

US08759604B2 Absorbent product 失效
标题翻译：吸收产品
公开(公告)号：US08759604B2
公开(公告)日：2014-06-24
申请号：US12096682
申请日：2005-12-09
申请人： Ulla Forsgren Brusk , Chatrine Stridfeldt , Arie Cornelis Besemer
发明人： Ulla Forsgren Brusk , Chatrine Stridfeldt , Arie Cornelis Besemer
IPC分类号： A61F13/15 , A61F13/20 , A61F13/84 , A61F13/51
CPC分类号： A61F13/8405 , A61F2013/5109 , A61F2013/8408 , A61L15/28 , A61L15/46 , A61L2300/10 , A61L2300/108 , A61L2300/232 , A61L2300/802 , C08L3/02
摘要： Absorbent product, such as a diaper, a sanitary napkin or an incontinence product, having a longitudinal and a lateral direction, including a back sheet, being distal from the body of the wearer in use of the product, and a top sheet, being proximal to the body of the wearer in use of the product, the product having a front part, a rear part and a crotch part lying between the front and rear parts, the product further including an absorbent structure, between the top and back sheet, extending longitudinally from the front part to the rear part, and whereby the product includes at least one starch-based odor control agent having a specific area of at least 5 m2/g, preferably at least 10 m2/g, more preferably at least 50 m2/g, even more preferably at least 100 m2/g, and most preferably at least 200 m2/g. Hereby, an enhanced capacity to absorb malodorous compounds of large size intervals in wet and dry systems is achieved.
摘要翻译：具有纵向和横向方向的吸收性产品，例如尿布，卫生巾或失禁产品，其包括背面片，其使用该产品远离使用者的身体，以及顶片在使用该产品的同时，该产品具有位于前部和后部之间的前部，后部和裆部，产品还包括吸收结构，位于顶部和背面之间，延伸纵向地从前部到后部，并且由此产品包括至少一种具有至少5m 2 / g，优选至少10m 2 / g，更优选至少50m 2的比表面积的基于淀粉的气味控制剂 g，甚至更优选至少100m2 / g，最优选至少200m2 / g。因此，实现了在湿和干系统中增加大尺寸间隔的恶臭化合物的能力。

9. 发明申请

US20120148659A1 SOLID DRESSING FOR TREATING WOUNDED TISSUE 审中-公开
标题翻译：用于治疗有创组织的固体治疗
公开(公告)号：US20120148659A1
公开(公告)日：2012-06-14
申请号：US13364762
申请日：2012-02-02
申请人： Martin MacPhee , Dawson Beall
发明人： Martin MacPhee , Dawson Beall
IPC分类号： A61L15/44 , A61K38/18 , A61K39/395 , A61F13/02 , A61K9/127 , A61K38/48 , A61K35/58 , A61K38/36 , A61K38/22
CPC分类号： A61L15/64 , A61F13/00012 , A61F13/00017 , A61F13/00021 , A61F13/00029 , A61F13/00034 , A61F13/00063 , A61F13/00068 , A61F13/00991 , A61F13/02 , A61F13/0226 , A61F13/0246 , A61F2013/00106 , A61F2013/00174 , A61F2013/00472 , A61F2013/00536 , A61F2013/0054 , A61F2013/0091 , A61F2013/00931 , A61K38/363 , A61K38/4833 , A61L15/18 , A61L15/225 , A61L15/26 , A61L15/28 , A61L15/32 , A61L15/325 , A61L15/38 , A61L15/44 , A61L15/58 , A61L26/0042 , A61L26/0052 , A61L26/0066 , A61L26/009 , A61L2300/10 , A61L2300/252 , A61L2300/254 , A61L2300/418 , A61L2300/604 , A61L2300/606 , A61L2300/608 , A61L2400/04 , C12Y304/21005 , C08L89/00
摘要： Disclosed are solid dressings for treated wounded tissue in mammalian patients, such as a human, comprising a haemostatic layer consisting essentially of a fibrinogen component and a fibrinogen activator, wherein the haemostatic layer(s) is cast or formed from a single aqueous solution containing the fibrinogen component and the fibrinogen activator. Also disclosed are methods for treating wounded tissue using these dressings and frozen compositions useful for preparing the haemostatic layer(s) of these dressings.
摘要翻译：公开了用于哺乳动物患者例如人的治疗伤口组织的固体敷料，其包含基本上由纤维蛋白原组分和纤维蛋白原激活剂组成的止血层，其中止血层由含有纤维蛋白原组分和纤维蛋白原激活剂。还公开了使用这些敷料和用于制备这些敷料的止血层的冷冻组合物来治疗伤口组织的方法。

10. 发明申请

US20110295090A1 Systems, devices, and methods including implantable devices with anti-microbial properties 审中-公开
公开(公告)号：US20110295090A1
公开(公告)日：2011-12-01
申请号：US12931927
申请日：2011-02-14
申请人： Edward S. Boyden , Roy P. Diaz , Roderick A. Hyde , Jordin T. Kare , Elizabeth A. Sweeney , Lowell L. Wood, JR.
发明人： Edward S. Boyden , Roy P. Diaz , Roderick A. Hyde , Jordin T. Kare , Elizabeth A. Sweeney , Lowell L. Wood, JR.
IPC分类号： A61B5/00
CPC分类号： A61L2/24 , A61L2/0011 , A61L2/08 , A61L2/14 , A61L2/232 , A61L2/26 , A61L17/145 , A61L27/28 , A61L27/306 , A61L27/54 , A61L29/00 , A61L29/08 , A61L29/16 , A61L31/024 , A61L31/026 , A61L31/08 , A61L31/14 , A61L31/16 , A61L2202/14 , A61L2300/10 , A61L2300/108 , A61L2300/404 , A61L2300/606 , A61M25/0045 , A61M27/006 , B82Y5/00 , B82Y30/00 , B82Y40/00
摘要： Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant.

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