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    • 9. 发明授权
    • Balanced myristate- and laurate-containing edible oil
    • 平衡的肉豆蔻酸和含月桂酸的食用油
    • US09491955B2
    • 2016-11-15
    • US13836505
    • 2013-03-15
    • Brandeis University
    • Daniel PerlmanKenneth C. Hayes
    • A23D9/00A23D7/00
    • A23D9/00A23D7/001A23D7/003
    • Nutritional fat or oil-based compositions for increasing HDL cholesterol, decreasing total cholesterol (TC), LDL cholesterol and decreasing the LDL/HDL cholesterol ratio in human plasma are described. The compositions can advantageously include at least 10% of myristic acid and/or lauric acid in which at least 3% of said fatty acid composition is myristic acid and at least 3% is lauric acid; in some cases at least 1% by weight myristic acid and/or lauric acid is esterified at the sn-2 position in triglyceride molecules. The compositions also include between 5% and 40% by weight linoleic acid, and typically further include at least 10% by weight monounsaturated fatty acids and between 15% and 55% by weight total saturated fatty acids. The sum of weight percentages for saturated, monounsaturated and polyunsaturated fatty acids equals 100%. In desirable cases, the composition is substantially cholesterol-free. Also described are fat compositions and diets which are adapted to limit increases in blood triglycerides, total cholesterol, LDL, and VLDL, even in the presence of dietary cholesterol.
    • 描述了用于增加HDL胆固醇,降低总胆固醇(TC),低密度脂蛋白胆固醇和降低人血浆中LDL / HDL胆固醇比例的营养脂肪或油基组合物。 组合物可以有利地包括至少10%的肉豆蔻酸和/或月桂酸,其中至少3%的所述脂肪酸组合物是肉豆蔻酸,并且至少3%是月桂酸; 在一些情况下,至少1重量%的肉豆蔻酸和/或月桂酸在甘油三酯分子的sn-2位被酯化。 组合物还包括5重量%至40重量%的亚油酸,并且通常还包括至少10重量%的单不饱和脂肪酸和15重量%至55重量%的总饱和脂肪酸。 饱和,单不饱和和多不饱和脂肪酸的重量百分比之和等于100%。 在期望的情况下,组合物基本上不含胆固醇。 还描述了脂肪组合物和饮食,其适于限制血液甘油三酯,总胆固醇,低密度脂蛋白和VLDL的增加,即使在膳食胆固醇的存在下。