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    • 4. 发明申请
    • Composite Material and Method for Production Thereof
    • 复合材料及其生产方法
    • US20100184864A1
    • 2010-07-22
    • US12665021
    • 2008-06-27
    • Tadashi HamajimaTomomi YanagibayashiRyuji ArakawaMorihiro AoyagiMasayoshi Kushi
    • Tadashi HamajimaTomomi YanagibayashiRyuji ArakawaMorihiro AoyagiMasayoshi Kushi
    • A61K31/16A61K8/42A61P1/00A61P3/00A61P9/00A23D9/007
    • A61K31/165A23L27/84A23L33/105C07B63/02
    • Disclosed are: a material which contains a lipophilic component having a pungent taste or flavor such as a spicy component (e.g., a capsaicin) and a bitter component (e.g., a turmeric extract), in which the pungent taste and/or flavor of the lipophilic component can be reduced effectively, and in which the separation among components contained therein is not caused; a method for producing the material; a composition such as a food, a beverage, a cosmetic and a medicine, which contains the material; and a liquid composition having such a form that the material is dispersed in water. Specifically disclosed are: a composite material comprising a lipophilic component having a pungent taste and/or flavor, a plant-derived cholesterol ester and a cyclodextrin; a composition comprising the composite material; a liquid composition which comprises the composite material, water and a thickening agent and has such a form that the composite material is dispersed in water; and a method for producing a composite material comprising a lipophilic component having a pungent taste and/or flavor, a plant-derived cholesterol ester and a cyclodextrin, which comprises mixing the lipophilic component, the plant-derived cholesterol ester and the cyclodextrin in the presence of water to form the composite material.
    • 公开的是含有具有刺激性味道或风味的亲脂成分如辣成分(例如辣椒素)和苦味成分(例如姜黄提取物)的材料,其中刺激性味道和/或香味 能够有效地降低亲油性成分,并且不会引起其中所含的成分之间的分离; 一种生产该材料的方法; 包含所述材料的组合物,例如食品,饮料,化妆品和药物; 以及具有使材料分散在水中的形式的液体组合物。 具体公开的是:复合材料,其包含具有刺激味道和/或风味的亲脂性组分,植物来源的胆固醇酯和环糊精; 包含所述复合材料的组合物; 包含复合材料,水和增稠剂并具有复合材料分散在水中的形式的液体组合物; 以及一种制备复合材料的方法,该复合材料包含具有刺激味道和/或风味的亲脂性组分,植物来源的胆固醇酯和环糊精,其包括在存在下混合亲油性组分,植物来源的胆固醇酯和环糊精 的水形成复合材料。
    • 5. 发明申请
    • GENE OF ENZYME HAVING ACTIVITY TO GENERATE LACHRYMATORY FACTOR
    • 具有活性的酵母基因生成LACHRYMATORY因子
    • US20090081754A1
    • 2009-03-26
    • US12051023
    • 2008-03-19
    • Shinsuke IMAINobuaki TsugeMuneaki Tomotake
    • Shinsuke IMAINobuaki TsugeMuneaki Tomotake
    • C12N9/00C12N15/52C12N15/74C07H21/02C12N1/00
    • C12N9/90C07K14/415C12N9/88
    • It is an object of the present invention to provide isozymes of the lachrymatory factor producing enzyme, the amino acid sequences of these isozymes and a gene that codes for these amino acid sequences, and the present invention relates to three types of isozymes of the lachrymatory factor producing enzyme that contributes to the production of the lachrymatory factor that is present in onions and the like, amino acid sequences indicated by SEQ ID Nos. 1 to 3 which constitute the proteins or polypeptides of these isozymes, DNA indicated by SEQ ID Nos. 4 and 5 which contains base sequences that code for the abovementioned proteins or polypeptides, a method of producing the abovementioned isozymes, a recombinant vector which contains the abovementioned DNA, a transformant formed by transforming a host cell with the abovementioned recombinant vector, a method of producing proteins or polypeptides that have lachrymatory factor producing enzyme activity by culturing the abovementioned host cell, and anti-sense RNA which has a base sequence that is complementary to that of the mRNA corresponding to the abovementioned DNA.
    • 本发明的一个目的是提供产生泪液因子的酶的同工酶,这些同工酶的氨基酸序列和编码这些氨基酸序列的基因,本发明涉及三种类型的变应原因子的同功酶 产生有助于产生存在于洋葱等中的变应原因子的酶,由构成这些同功酶的蛋白质或多肽的SEQ ID NO.1至3表示的氨基酸序列,SEQ ID No.4所示的DNA 和5,其包含编码上述蛋白质或多肽的碱基序列,产生上述同功酶的方法,含有上述DNA的重组载体,通过用上述重组载体转化宿主细胞形成的转化体,制备 蛋白质或多肽,其具有通过培养上述宿主c产生酶活性的lachrymatory因子 和具有与对应于上述DNA的mRNA互补的碱基序列的反义RNA。
    • 6. 发明授权
    • Isozymes of lacrimator component synthase and gene encoding the same
    • 流感组分合成酶的同工酶和编码相同的基因
    • US07371554B2
    • 2008-05-13
    • US10344158
    • 2001-08-30
    • Shinsuke ImaiNobuaki TsugeMuneaki Tomotake
    • Shinsuke ImaiNobuaki TsugeMuneaki Tomotake
    • C12N9/00C12N9/88C07H21/04
    • C12N9/90C07K14/415C12N9/88
    • It is an object of the present invention to provide isozymes of the lachrymatory factor producing enzyme, the amino acid sequences of these isozymes and a gene that codes for these amino acid sequences, and the present invention relates to three types of isozymes of the lachrymatory factor producing enzyme that contributes to the production of the lachrymatory factor that is present in onions and the like, amino acid sequences indicated by SEQ ID Nos. 1 to 3 which constitute the proteins or polypeptides of these isozymes, DNA indicated by SEQ ID Nos. 4 and 5 which contains base sequences that code for the abovementioned proteins or polypeptides, a method of producing the abovementioned isozymes, a recombinant vector which contains the abovementioned DNA, a transformant formed by transforming a host cell with the abovementioned recombinant vector, a method of producing proteins or polypeptides that have lachrymatory factor producing enzyme activity by culturing the abovementioned host cell, and anti-sense RNA which has a base sequence that is complementary to that of the mRNA corresponding to the abovementioned DNA.
    • 本发明的一个目的是提供产生泪液因子的酶的同工酶,这些同工酶的氨基酸序列和编码这些氨基酸序列的基因,本发明涉及三种类型的变应原因子的同功酶 产生有助于产生存在于洋葱等中的变应原因子的酶,由构成这些同功酶的蛋白质或多肽的SEQ ID NO.1至3表示的氨基酸序列,SEQ ID No.4所示的DNA 和5,其包含编码上述蛋白质或多肽的碱基序列,产生上述同功酶的方法,含有上述DNA的重组载体,通过用上述重组载体转化宿主细胞形成的转化体,制备 蛋白质或多肽,其具有通过培养上述宿主c产生酶活性的lachrymatory因子 和具有与对应于上述DNA的mRNA互补的碱基序列的反义RNA。
    • 7. 发明申请
    • Method for detecting target plant genus
    • 检测目标植物属的方法
    • US20070048779A1
    • 2007-03-01
    • US11581872
    • 2006-10-17
    • Takashi HiraoMasayuki Hiramoto
    • Takashi HiraoMasayuki Hiramoto
    • C12Q1/68C12P19/34
    • C12Q1/6895
    • A method for detecting species in a target plant genus comprises the steps of conducting PCR using at least one member selected from the group consisting of primers (A) and (B), which can hybridize under stringent conditions to a nucleic acid molecule having a common nucleotide sequence for all species in the target plant genus in 45S rRNA precursor gene sequence thereof, wherein 3′ end of primer (A) can complementarily bind to a base in ITS-1 sequence of the target plant genus when the primer hybridizes to the nucleic acid molecule while 3′ end of primer (B) can complementarily bind to a base in ITS-2 sequence of the target plant genus when the primer hybridizes to the nucleic acid molecule, and identifying the presence of the resulting amplification product from PCR containing at least a part of ITS-1 or ITS-2 sequence of the target plant genus. The method for detecting species in a target plant genus, particularly an allergenic plant genus such as the genus Fagopyrum, can make it possible to detect with high sensitivity, for example, about 1 ppm of the plant(s) in cases where the plant(s) is contained in a food ingredient or food product.
    • 一种用于检测目标植物属物种的方法,包括以下步骤:使用选自引物(A)和(B)中的至少一种成员进行PCR,其可在严格条件下与具有共同的核酸分子杂交 在45S rRNA前体基因序列中的目标植物属中的所有物种的核苷酸序列,其中引物(A)的3'末端可以在引物与核酸杂交时与靶植物属的ITS-1序列中的碱基互补结合 酸分子,而当引物与核酸分子杂交时,引物(B)的3'末端可以与靶植物属的ITS-2序列中的碱基互补结合,并且从PCR中鉴定所得扩增产物的存在, 目标植物属的ITS-1或ITS-2序列的至少一部分。 用于检测目标植物属,特别是变应原植物属(如禾本科)的物种的方法可以使得可以以高灵敏度检测例如约1ppm的植物(例如植物( s)包含在食品成分或食品中。
    • 8. 发明授权
    • Method for detecting target plant genus
    • 检测目标植物属的方法
    • US07144702B2
    • 2006-12-05
    • US10285061
    • 2002-10-31
    • Takashi HiraoMasayuki Hiramoto
    • Takashi HiraoMasayuki Hiramoto
    • C12Q1/68C12P19/34
    • C12Q1/6895
    • A method for detecting species in a target plant genus comprises the steps of conducting PCR using at least one member selected from the group consisting of primers (A) and (B), which can hybridize under stringent conditions to a nucleic acid molecule having a common nucleotide sequence for all species in the target plant genus in 45S rRNA precursor gene sequence thereof, wherein 3′ end of primer (A) can complementarily bind to a base in ITS-1 sequence of the target plant genus when the primer hybridizes to the nucleic acid molecule while 3′ end of primer (B) can complementarily bind to a base in ITS-2 sequence of the target plant genus when the primer hybridizes to the nucleic acid molecule, and identifying the presence of the resulting amplification product from PCR containing at least a part of ITS-1 or ITS-2 sequence of the target plant genus.The method for detecting species in a target plant genus, particularly an allergenic plant genus such as the genus Fagopyrum, can make it possible to detect with high sensitivity, for example, about 1 ppm of the plant(s) in cases where the plant(s) is contained in a food ingredient or food product.
    • 一种用于检测目标植物属物种的方法,包括以下步骤:使用选自引物(A)和(B)中的至少一种成员进行PCR,其可在严格条件下与具有共同的核酸分子杂交 在45S rRNA前体基因序列中的目标植物属中的所有物种的核苷酸序列,其中引物(A)的3'末端可以在引物与核酸杂交时与靶植物属的ITS-1序列中的碱基互补结合 酸分子,而当引物与核酸分子杂交时,引物(B)的3'末端可以与靶植物属的ITS-2序列中的碱基互补结合,并且从PCR中鉴定所得扩增产物的存在, 目标植物属的ITS-1或ITS-2序列的至少一部分。 用于检测目标植物属,特别是变应原植物属(如禾本科)的物种的方法可以使得可以以高灵敏度检测例如约1ppm的植物(例如植物( s)包含在食品成分或食品中。
    • 9. 发明申请
    • Method for detecting target plant genus
    • 检测目标植物属的方法
    • US20030207298A1
    • 2003-11-06
    • US10285061
    • 2002-10-31
    • House Foods Corporation
    • Takashi HiraoMasayuki Hiramoto
    • C12Q001/68C12P019/34
    • C12Q1/6895
    • A method for detecting species in a target plant genus comprises the steps of conducting PCR using at least one member selected from the group consisting of primers (A) and (B), which can hybridize under stringent conditions to a nucleic acid molecule having a common nucleotide sequence for all species in. the target plant genus in 45S rRNA precursor gene sequence thereof, wherein 3null end of primer (A) can complementarily bind to a base in ITS-1 sequence of the target plant genus when the primer hybridizes to the nucleic acid molecule while 3null end of primer (B) can complementarily bind to a base in ITS-2 sequence of the target plant genus when the primer hybridizes to the nucleic acid molecule, and identifying the presence of the resulting amplification product from PCR containing at least a part of ITS-1 or ITS-2 sequence of the target plant genus. The method for detecting species in a target plant genus, particularly an allergenic plant genus such as the genus Fagopyrum, can make it possible to detect with high sensitivity, for example, about 1 ppm of the plant(s) in cases where the plant(s) is contained in a food ingredient or food product.
    • 一种用于检测目标植物属物种的方法,包括以下步骤:使用选自引物(A)和(B)中的至少一种成员进行PCR,其可在严格条件下与具有共同的核酸分子杂交 在45S rRNA前体基因序列中的目标植物属中的所有物种的核苷酸序列,其中引物(A)的3'末端可以在引物与目的植物属的ITS-1序列杂交时与靶植物属的ITS-1序列中的碱基互补结合 核酸分子,而当引物与核酸分子杂交时,引物(B)的3'末端可以与目标植物属的ITS-2序列中的碱基互补结合,并且鉴定来自PCR的所得扩增产物的存在 目标植物属的ITS-1或ITS-2序列的至少一部分。 用于检测目标植物属,特别是变应原植物属(如禾本科)的物种的方法可以使得可以以高灵敏度检测例如约1ppm的植物(例如植物( s)包含在食品成分或食品中。