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1. 发明公开

US20240376129A1 METALLODRUG THERAPEUTIC COMPOUNDS AND PRODRUGS OF METALLODRUG THERAPEUTIC COMPOUNDS 审中-公开
公开(公告)号：US20240376129A1
公开(公告)日：2024-11-14
申请号：US18688719
申请日：2022-09-01
申请人： Dublin City University
发明人： Andrew Kellett , Natasha McStay
IPC分类号： C07F1/00 , C07D249/04 , C07D401/14 , C07D403/14 , C07D409/14 , C07D417/14 , C07D471/04
CPC分类号： C07F1/005 , C07D249/04 , C07D401/14 , C07D403/14 , C07D409/14 , C07D417/14 , C07D471/04
摘要： Disclosed herein are compounds of various formulas. In particular, the compounds are metallodrug therapeutic compounds or prodrugs of metallodrug therapeutic compounds. The metallodrug therapeutic compounds and prodrugs of metallodrug therapeutic compounds are for use in therapy, for example in the treatment and detection of cancer.

2. 发明授权

US11995438B2 System and method for software architecture redesign 有权
公开(公告)号：US11995438B2
公开(公告)日：2024-05-28
申请号：US17764152
申请日：2020-09-30
申请人： Dublin City University
发明人： Paul Clarke , Andrew McCarren
IPC分类号： G06F8/72 , G06F8/20 , G06F8/71
CPC分类号： G06F8/72 , G06F8/24 , G06F8/71
摘要： The present invention provides a system and method for automation of the creation of a software application as a combination of microservices by extraction of discrete elements of software functionality from a monolithic architectures using dynamic and static analysis of code and non-code-related artefacts; forming them into microservices such that the software application is recreated as serverless hardware infrastructure while also validating the transformed code. In many cases, serverless microservices will significantly reduce the hardware requirement for software systems.

3. 发明公开

US20230370165A1 OPTICAL LINEWIDTH INDEPENDENT HIGH PURITY MMW/THZ GENERATOR EMPLOYING CASCADED DEMULTIPLEXING 审中-公开
公开(公告)号：US20230370165A1
公开(公告)日：2023-11-16
申请号：US18250166
申请日：2021-10-22
申请人： DUBLIN CITY UNIVERSITY
发明人： Prajwal Doddaballapura , Aleksandra Kaszubowska-Anandarajah , Prince Anandarajah
IPC分类号： H04B10/2575 , H04J14/02
CPC分类号： H04B10/2575 , H04J14/0298 , H04B2210/006
摘要： The invention provides an optical generator and method comprising an Optical Frequency Comb configured to generate a plurality of frequency tones and fed to a first demultiplexer, wherein the first demultiplexer is configured to injection lock at least one desired frequency tone; and a second demultiplexer connected to the first demultiplexer and configured to injection lock a second frequency tone from said plurality of frequency tones wherein the output of the second demultiplexer comprise two injection locked frequency tones separated by a desired frequency. The invention enables the generation of high frequency signals (>30 GHz) that exhibit high levels of purity (required for many applications). Moreover, the invention simplifies the architecture, by reducing the real estate occupied by the components. This is most important when all the devices involved are integrated onto a single chip.

4. 发明公开

US20230230821A1 SYSTEM AND METHOD FOR REMOTE SENSING A PLASMA 审中-公开
公开(公告)号：US20230230821A1
公开(公告)日：2023-07-20
申请号：US17946189
申请日：2022-09-16
申请人： DUBLIN CITY UNIVERSITY
发明人： Patrick J. McNally , Sean Kelly
IPC分类号： H01J37/32
CPC分类号： H01J37/32963 , H01J37/32972 , H01J37/3299
摘要： The invention provides a method and system to remotely monitor a plasma (3) comprising a magnetic field antenna (2) positioned in the near electromagnetic field of a coupled plasma source wherein the magnetic field antenna is a magnetic loop antenna placed in the near electromagnetic field and measure near field signals emitted from the plasma source. A radio system (1) is utilised to analyse the low power signal levels across a wide frequency band. Plasma paramaters such as series, or geometric, resonance plasma and electron-neutral collision frequencies are evaluated via a fitting of resonant features present on higher harmonics of the driving frequency to identify arcing, pump or matching failure events, common in fabrication plasma systems.

5. 发明申请

US20230037522A1 MICROFLUIDIC DEVICE FOR DETECTION OF ANALYTES 有权
公开(公告)号：US20230037522A1
公开(公告)日：2023-02-09
申请号：US17857824
申请日：2022-07-05
申请人： DUBLIN CITY UNIVERSITY
发明人： Robert Forster , Elaine Spain , Kellie Adamson , Eadaoin Carthy , David Boyle
IPC分类号： B01L3/00 , G01N27/07 , G01N33/543 , G01N33/569 , G01N33/577 , G01N35/00
摘要： A microfluidic device for detection of an analyte in a fluid is described. The microfluidic device comprises a substrate having a first surface defining entrances to one or more chambers defined in the substrate, surfaces of the chambers defining a second surface of the substrate, the first surface being modified for selective targeting and capture of at least one analyte to operably effect a blocking of the entrance to at least one of the chambers, and wherein a response characteristic of the microfluidic device is operably varied by the blocking of the entrance to the at least one of the chambers, thereby providing an indication of the presence of the analyte within the fluid.

6. 发明授权

US11344888B2 Fluidic device for aliquoting and combinatorial mixing of liquids 有权
公开(公告)号：US11344888B2
公开(公告)日：2022-05-31
申请号：US16464982
申请日：2017-11-28
申请人： DUBLIN CITY UNIVERSITY
发明人： David Kinahan , Jens Ducree
IPC分类号： B01L3/00 , B01L9/00 , B01F33/81 , B01F33/301 , B01F35/71 , B01F101/23
摘要： The present invention relates to fluidic devices, especially microfluidic devices, for aliquoting and pairwise combinatorial mixing of a first set of liquids with a second set of liquids. The device architecture is designed to move liquids in two separate phases, a first phase where the liquids are exposed to a first directional force field to move the liquids in a first direction, from a reservoir to aliquot chambers, and a second phase where the liquids are exposed to a second directional force field to move the liquids in a second direction, from the aliquot chambers to the mixing chambers. The first and second directional force fields that the device is exposed to may be achieved using a single directional force field (i.e. a rotor driven centrifugal force field) and by re-orienting the position of the device with respect to the centrifugal forces between the first and second phases of operation. The device architecture comprises reservoirs for each of the first fluids and reservoirs for each of the second fluids. Each reservoir is fluidically connected to aliquoting chambers, either arranged in parallel or in series, for providing aliquots of the fluid which may be metered. The conduits providing fluid communication between the reservoirs and aliquoting chambers are arranged in a first direction. A series of mixing chambers is also provided, and each mixing chamber is fluidically connected to one aliquot chamber for a first liquid and one aliquoting chamber for a second liquid. The conduits providing fluid communication between the aliquoting chambers and mixing chambers are arranged in a second direction.

7. 发明申请

US20210021911A1 METHOD AND SYSTEM FOR ENCODING AND DECODING MULSEMEDIA STREAMS 有权
公开(公告)号：US20210021911A1
公开(公告)日：2021-01-21
申请号：US16912860
申请日：2020-06-26
申请人： Dublin City University
发明人： Bi Ting , Zou Longhao
IPC分类号： H04N21/845 , H04N21/2343 , H04L29/06 , H04L29/08
摘要： The method and system of the present invention provides Dynamic Adaptive Streaming over HTTP (DASH)-based Adaptive Rich Media Delivery Solution (DASH-ARM) which performs adaptive delivery of mulsemedia content by improving the perceived QoE levels which improves user's sense of reality. In its dynamic adjustment of multiple sensorial content characteristics, DASH-ARM performs a trade-off between video quality and presence of diverse other sensorial components which include components such as haptic, olfaction and wind. This trade-off relies on the fact that the presence of other sensorial components has a masking effect on potential audio/video quality variations. DASH-ARM is complemented by an adaptive multi-sensory media stream (mulsemedia) which synchronizes at the user device, where the multimedia content and mulsemedia comprises diverse sensorial stimuli.

8. 发明授权

US09444117B2 Proton exchange membrane fuel cell with open pore cellular foam 有权
标题翻译：质子交换膜燃料电池与开孔细胞泡沫
公开(公告)号：US09444117B2
公开(公告)日：2016-09-13
申请号：US14426653
申请日：2013-09-06
申请人： Dublin City University
发明人： Abdul Ghani Olabi , James Gerard Carton
IPC分类号： H01M8/0232 , H01M8/04029 , H01M8/0258 , H01M8/24 , H01M4/86 , H01M8/02 , C25B9/18
CPC分类号： H01M8/0232 , C25B9/18 , H01M4/8605 , H01M8/241 , H01M8/2483 , Y02E60/50 , Y02E60/521
摘要： The present application relates generally to electrochemical devices, for example proton exchange membrane fuel cells or electrolysers. The present application employs a metal foam as a common fluid flow manifold between adjacent fuel cells and avoids the use of expensive metal end plates. The common fluid flow manifold is provided by the metal foam with no separator/gas barrier provided.
摘要翻译：本申请一般涉及电化学装置，例如质子交换膜燃料电池或电解槽。本申请使用金属泡沫作为相邻燃料电池之间的常见流体流动歧管，并避免使用昂贵的金属端板。公共流体流动歧管由金属泡沫提供，没有提供隔板/气体屏障。

9. 发明授权

US09385506B2 Wavelength tunable comb source 有权
标题翻译：波长可调梳源
公开(公告)号：US09385506B2
公开(公告)日：2016-07-05
申请号：US14343675
申请日：2012-09-12
申请人： Prince Anandarajah , Sylwester Latkowski , Liam Barry
发明人： Prince Anandarajah , Sylwester Latkowski , Liam Barry
IPC分类号： H01S5/065 , H01S5/40 , H04B10/50 , H01S5/00 , H01S5/042 , H01S5/10
CPC分类号： H01S5/065 , H01S5/0064 , H01S5/0085 , H01S5/0427 , H01S5/0656 , H01S5/1096 , H01S5/40 , H01S5/4006 , H04B10/506
摘要： The present application provides an optical comb source in which the comb is produced by seeding a gain switched Fabry-Pérot laser with light from a single mode laser, while at the same time driving the Fabry-Pérot laser with a DC bias and RF signal.
摘要翻译：本申请提供了一种光梳源，其中通过用来自单模激光的光种子增益切换法布里 - 珀罗激光器同时通过DC偏压和RF信号驱动法布里 - 珀罗激光器来产生梳子。

10. 发明授权

US09291628B2 Direct clone analysis and selection technology 有权
标题翻译：直接克隆分析和选择技术
公开(公告)号：US09291628B2
公开(公告)日：2016-03-22
申请号：US13809833
申请日：2011-07-13
申请人： Paul Leonard , Ivan Dimov , Richard O'Kennedy , Valerie Fitzgerald
发明人： Paul Leonard , Ivan Dimov , Richard O'Kennedy , Valerie Fitzgerald
IPC分类号： G01N33/53 , G01N33/68 , B01L3/00
CPC分类号： G01N33/54306 , B01L3/5085 , B01L3/50857 , B01L2300/0636 , B01L2300/0819 , B01L2300/12 , B01L2300/16 , C12Q1/6818 , C12Q1/6837 , G01N33/53 , G01N33/5302 , G01N33/545 , G01N33/569 , G01N33/68
摘要： The present invention describes a spatial addressing technique that uses a very high-density micro-pore array for high-throughput screening of biological interactions. The therapeutic, diagnostic and drug-discovery implications of being able to identify, select and characterize specific protein-protein, protein-DNA and/or protein-carbohydrate interactions from heterogeneous populations of millions (to billions) of cells is discussed. Importantly, this technique possesses the screening and selection capacity of current display-based screening systems (i.e., millions-billions) but with greater efficiency and shorter time.
摘要翻译：本发明描述了使用非常高密度的微孔阵列进行生物相互作用的高通量筛选的空间寻址技术。讨论了能够识别，选择和表征特定蛋白质蛋白质，蛋白质DNA和/或蛋白质 - 碳水化合物相互作用的治疗，诊断和药物发现影响，从数百万（至数十亿）细胞的异质群体。重要的是，该技术具有当前基于显示屏的筛选系统（即数百万亿）的筛选和选择能力，但具有更高的效率和更短的时间。

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