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1. 发明授权

US09039752B2 Device and method for delivering a vascular device 有权
标题翻译：用于输送血管装置的装置和方法
公开(公告)号：US09039752B2
公开(公告)日：2015-05-26
申请号：US13236803
申请日：2011-09-20
申请人： Patrick Russo , Mark Krans , Matthew C. Heidner
发明人： Patrick Russo , Mark Krans , Matthew C. Heidner
IPC分类号： A61F2/966 , A61F2/95
CPC分类号： A61F2/966 , A61F2002/9522 , A61F2002/9534 , A61F2002/9665
摘要： A device and method for delivering a vascular device to a target site is provided that maintains a proximal portion of the vascular device within a tubular sleeve by positioning a stop of an inner member at a distal opening of the tubular sleeve to block the opening. Once the stop has been moved distally via movement of the inner member to clear the opening, a band of increased thickness on the inner member can urge the proximal portion of the vascular device out of the tubular sleeve to deploy the vascular device. The vascular device may be recaptured within a delivery sheath prior to the full deployment of the proximal portion of the vascular device from the tubular sleeve by re-positioning the stop at the distal opening to hold the vascular device within the tubular sleeve as the delivery device is retracted with respect to the delivery sheath.
摘要翻译：提供了一种用于将血管装置输送到目标部位的装置和方法，其通过将内部构件的止动件定位在管状套管的远端开口处以阻止开口，从而将血管装置的近端部分保持在管状套筒内。一旦通过内部构件的运动使止挡件向远侧移动以清除开口，则内部构件上的厚度增加的带可将血管装置的近端部分推出管状套管以展开血管装置。在将血管装置的近端部分从管状套管完全展开之前，血管装置可以在输送护套内重新捕获，通过将止动件重新定位在远侧开口处，以将血管装置保持在管状套筒内作为输送装置相对于输送护套缩回。

2. 发明授权

US09039724B2 Device for occluding vascular defects 有权
标题翻译：用于阻塞血管缺陷的装置
公开(公告)号：US09039724B2
公开(公告)日：2015-05-26
申请号：US12208787
申请日：2008-09-11
申请人： Kurt Amplatz , Matthew C. Heidner , Patrick Russo , Brooke Ren , Daniel O. Adams
发明人： Kurt Amplatz , Matthew C. Heidner , Patrick Russo , Brooke Ren , Daniel O. Adams
IPC分类号： A61B17/00 , A61B17/12 , A61B19/00
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12113 , A61B17/12122 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B17/12177 , A61B90/39 , A61B2017/00575 , A61B2017/00601 , A61B2017/00606 , A61B2017/00831
摘要： A multi-layer occluder for treating a target site within the body is provided. The occluder may include first and second layers. For example, the first layer may include braided strands of metallic material, and the second layer may include braided strands of polymeric material. At least one of the first or second layers may be configured to facilitate thrombosis.
摘要翻译：提供了用于治疗身体内的靶部位的多层封堵器。封堵器可以包括第一和第二层。例如，第一层可以包括金属材料的编织线，并且第二层可以包括聚合材料的编织线。第一或第二层中的至少一个可以被配置为便于血栓形成。

3. 发明授权

US08961556B2 Percutaneous catheter directed intravascular occlusion devices 有权
公开(公告)号：US08961556B2
公开(公告)日：2015-02-24
申请号：US13837351
申请日：2013-03-15
申请人： AGA Medical Corporation
发明人： Kurt Amplatz , Xiaoping Gu , John C. Oslund
IPC分类号： A61M29/00 , A61B17/12 , A61B17/00
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12122 , A61B17/12172 , A61B17/12177 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00628 , A61B2017/00632 , A61B2017/00867
摘要： The present invention provides an improved vascular occlusion device having improved flexibility and retention of the type fabricated from braided tubular metal fabric having an expanded preset configuration and an elongated collapsed reduced diameter configuration for delivery through a catheter to a treatment site and shaped to create an occlusion of an abnormal opening in a body organ or vessel, the woven metal fabric having a memory property whereby the medical device tends to return to said expanded preset configuration when unconstrained. The device further including at least one disk portion adjacent a body cylindrical portion formed from the fabric and having a transition diameter between the disk and cylindrical portion, significantly smaller than the diameter of the disk and the diameter of the cylindrical portion.

4. 发明申请

US20140277426A1 Paravalvular Leak Occlusion Device for Self-Expanding Heart Valves 审中-公开
标题翻译：用于自扩张心脏瓣膜的瓣膜泄漏阻塞装置
公开(公告)号：US20140277426A1
公开(公告)日：2014-09-18
申请号：US14096427
申请日：2013-12-04
申请人： AGA Medical Corporation
发明人： Gregory James Dakin , Peter Nicholas Braido
IPC分类号： A61F2/24
CPC分类号： A61F2/246 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2250/0003 , A61F2250/0069
摘要： An occluder device for occluding a gap between a medical device and adjacent body tissue includes a conformable body having a hollow interior, a leading end and a trailing end; and a port disposed at the trailing end of the body and in fluid communication with the interior of the body.
摘要翻译：用于封闭医疗装置和相邻身体组织之间的间隙的封堵器装置包括具有中空内部，前端和后端的适形主体; 以及设置在所述主体的后端并与所述主体的内部流体连通的端口。

5. 发明申请

US20140257374A1 PERCUTANEOUS CATHETER DIRECTED COLLAPSIBLE MEDICAL CLOSURE DEVICE 有权
公开(公告)号：US20140257374A1
公开(公告)日：2014-09-11
申请号：US13793289
申请日：2013-03-11
申请人： AGA MEDICAL CORPORATION
发明人： Jennifer Marie Heisel , Kevin Joseph Schutt
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B90/39 , A61B2017/00526 , A61B2017/00592 , A61B2017/00623 , A61B2017/00628 , A61B2017/00867 , A61B2090/3966
摘要： The present disclosure provides an improved collapsible medical closure device fabricated from a tubular wire mesh material. The collapsible medical closure device has an expanded preset configuration and an elongated collapsed reduced diameter configuration for delivery through a delivery catheter or other delivery means to a desired treatment site. The collapsible medical closure device is shaped to create short-term and long-term occlusion of an opening, such as an opening in the wall of the heart, and includes a disc shaped portion on a distal end, a cone shaped portion on a proximal end, a middle portion connecting the disc shaped portion and the cone shaped portion, and a means for attaching a delivery cable located in the middle portion. The collapsible medical closure device additionally includes a therapeutic membrane for aiding in occlusion and promoting tissue growth, as well as one or more radiopaque marker bands.
摘要翻译：本公开提供了一种由管状丝网材料制成的改进的可折叠医疗闭合装置。可折叠的医疗闭合装置具有扩展的预设构型和细长的折叠缩径直径构型，用于通过输送导管或其他递送装置输送到期望的治疗部位。可折叠医疗闭合装置被成形为产生开口的短期和长期闭塞，例如心脏壁中的开口，并且包括远端上的盘形部分，近端的锥形部分连接盘形部分和锥形部分的中间部分，以及用于附接位于中间部分中的输送电缆的装置。可折叠医疗闭合装置还包括用于帮助闭塞并促进组织生长的治疗膜以及一个或多个不透射线的标记带。

6. 发明授权

US08764787B2 Occlusion device and associated deployment method 有权
标题翻译：闭塞装置及相关部署方法
公开(公告)号：US08764787B2
公开(公告)日：2014-07-01
申请号：US13163313
申请日：2011-06-17
申请人： Brooke Ren
发明人： Brooke Ren
IPC分类号： A61M29/00
CPC分类号： A61B17/12122 , A61B17/12172
摘要： An occlusion device for occluding a cavity defined by a body is provided, and includes first and second laterally-expandable portions each formed of a woven tubular fabric and having opposed proximal and distal ends. The first portion is insertable into the cavity so as to be substantially disposed therein upon lateral expansion thereof. A connective element tethers the distal end of the first portion and the second portion, and is cooperable therewith to form a collapsible assembly extending along an insertion axis. Retention members, operably engaged with each of the first and second portions and spaced apart about a laterally outward surface thereof, are adapted to engage the body, after insertion of the collapsed assembly, second portion-first, into the cavity, and subsequent lateral expansion of the first and second portions, so as to retain the assembly substantially within the cavity. An associated deployment method is also provided.
摘要翻译：提供一种用于封闭由主体限定的空腔的闭塞装置，并且包括第一和第二横向可膨胀部分，每个由编织的管状织物形成并具有相对的近端和远端。第一部分可插入空腔中，以便在其侧向膨胀时基本上设置在其中。连接元件系固第一部分和第二部分的远端，并且与其配合以形成沿着插入轴线延伸的可折叠组件。与第一和第二部分中的每一个可操作地接合并且围绕其横向向外的表面间隔开的保持构件适于在将塌缩的组件插入第二部分之后接合主体，并且随后的横向膨胀的第一和第二部分，以便将组件基本上保持在空腔内。还提供了相关的部署方法。

7. 发明授权

US08361138B2 Braided occlusion device having repeating expanded volume segments separated by articulation segments 有权
公开(公告)号：US08361138B2
公开(公告)日：2013-01-29
申请号：US11881026
申请日：2007-07-25
申请人： Daniel O. Adams
发明人： Daniel O. Adams
IPC分类号： A61F2/06
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12122 , A61B17/12145 , A61B17/12154 , A61B17/12163 , A61B17/12172 , A61B17/12177 , A61B2017/00526 , A61B2017/00867
摘要： The present invention provides a flexible, low profile vascular occlusion device having large volume filling capability and high metal content for fast occlusion, of the type fabricated from braided tubular metal fabric having an expanded preset configuration and an elongated collapsed reduced diameter configuration for delivery through a catheter to a treatment site and shaped to create an occlusion of an abnormal opening in a body organ or vessel, the woven metal fabric having a memory property whereby the medical device tends to return to said expanded preset configuration when unconstrained. The device further includes a first shape formed from the braided tubular fabric consisting of a repeating pattern of expanded volume segments separated by small diameter articulation segments and a second overall device shape comprised of the first shape formed about itself in various shapes to occlude a vessel. In one embodiment a shaping wire contained coaxially within the tubular braid, provides or assists in the formation of the second overall device shape.

8. 发明申请

US20130012979A1 MULTI-LAYER BRAIDED STRUCTURES FOR OCCLUDING VASCULAR DEFECTS AND FOR OCCLUDING FLUID FLOW THROUGH PORTIONS OF THE VASCULATURE OF THE BODY 有权
标题翻译：用于阻断血管缺损和通过身体血管部分流体流动的多层布线结构
公开(公告)号：US20130012979A1
公开(公告)日：2013-01-10
申请号：US13618483
申请日：2012-09-14
申请人： Kurt Amplatz , Xiaoping Gu , John C. Oslund , Gary A. Thill
发明人： Kurt Amplatz , Xiaoping Gu , John C. Oslund , Gary A. Thill
IPC分类号： A61M29/00
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867
摘要： A collapsible medical device and associated methods of occluding an abnormal opening in, for example, a body organ, wherein the medical device is shaped from plural layers of a heat-treatable metal fabric. Each of the fabric layers is formed from a plurality of metal strands and the assembly is heat-treated within a mold in order to substantially set a desired shape of the device. By incorporating plural layers in the thus-formed medical device, the ability of the device to rapidly occlude an abnormal opening in a body organ is significantly improved.
摘要翻译：一种可折叠的医疗装置和在例如身体器官中闭塞异常开口的相关方法，其中所述医疗装置由多层可热处理的金属织物成形。每个织物层由多个金属线形成，并且该组件在模具内进行热处理，以便基本上设置该装置的期望形状。通过在如此形成的医疗装置中并入多层，显着提高了装置快速闭塞体内器官的异常开口的能力。

9. 发明授权

US08313505B2 Device for occluding vascular defects 有权
标题翻译：用于阻塞血管缺陷的装置
公开(公告)号：US08313505B2
公开(公告)日：2012-11-20
申请号：US12040260
申请日：2008-02-29
申请人： Kurt Amplatz , Matt Glimsdale , Jana Santer , Xiaoping Gu , John Oslund
发明人： Kurt Amplatz , Matt Glimsdale , Jana Santer , Xiaoping Gu , John Oslund
IPC分类号： A61F2/00
CPC分类号： A61B17/0057 , A61B17/12109 , A61B17/12122 , A61B17/12163 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00867 , A61B2017/12127
摘要： Embodiments of the present invention provide devices and methods for treating abnormalities. For example, a device according to one embodiment includes a plurality of planes of occlusion, at least one plane of occlusion comprising a plurality of layers of occlusive material. The device is configured to at least partially occlude an abnormality.
摘要翻译：本发明的实施例提供了用于治疗异常的装置和方法。例如，根据一个实施例的装置包括多个闭塞平面，至少一个闭塞平面包括多个封闭材料层。该装置被配置为至少部分地遮挡异常。

10. 发明申请

US20100023048A1 MULTI-LAYERED MEDICAL DEVICE FOR TREATING A TARGET SITE AND ASSOCIATED METHOD 有权
标题翻译：用于处理目标位置的多层医疗设备及相关方法
公开(公告)号：US20100023048A1
公开(公告)日：2010-01-28
申请号：US12179172
申请日：2008-07-24
申请人： RYAN MACH
发明人： RYAN MACH
IPC分类号： A61M25/10
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12172 , A61B17/12177 , A61B2017/00526 , A61B2017/00893 , A61B2017/00911 , A61M25/00 , A61M25/0026
摘要： Embodiments of the present invention provide medical devices and methods for treating a target site within the body, such as for treating vascular abnormalities. For example, one embodiment provides an occlusion device including an occlusive material having proximal and distal ends and a central axis extending therebetween. The occlusive material has a preset, overlapping configuration including at least three inverted overlapping layers folded over one another, wherein the at least three inverted overlapping layers are aligned with the central axis within about 45 degrees or less and are configured to be separated and disposed within a catheter in a non-overlapping configuration and return to the preset, overlapping configuration when deployed from the catheter.
摘要翻译：本发明的实施方案提供用于治疗体内靶点的医疗装置和方法，例如用于治疗血管异常。例如，一个实施例提供一种闭塞装置，其包括具有近端和远端以及在其间延伸的中心轴线的封闭材料。封闭材料具有包括彼此折叠的至少三个倒置的重叠层的预设的重叠构型，其中至少三个倒置的重叠层在约45度或更小的范围内与中心轴线对齐并且构造成分开并设置在导管处于不重叠的构造并且当从导管展开时返回到预设的重叠配置。

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