专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20070248685A1 DRY HEMOSTATIC COMPOSITIONS AND METHODS FOR THEIR PREPARATION 有权
标题翻译：干燥剂组合物及其制备方法
公开(公告)号：US20070248685A1
公开(公告)日：2007-10-25
申请号：US11766516
申请日：2007-06-21
申请人： Zhen Qian , A. Osawa , Cary Reich
发明人： Zhen Qian , A. Osawa , Cary Reich
IPC分类号： A61K9/14 , A61P7/04
CPC分类号： A61K38/4833 , A61L24/0031 , A61L24/104 , A61L2400/04
摘要： Dry cross-linked gelatin compositions are prepared that rapidly re-hydrate to produce gelatin hydrogels suitable as hemostatic sealants. Gelatin is cross-linked in the presence of certain re-hydration aids, such as polyethylene glycol, polyvinylprovidone, and dextran, in order to produce a dry cross-linked gelatin powder. The use of the re-hydration aids has been found to substantially increase the re-hydration rate in the presence of an aqueous re-hydration medium, typically thrombin-containing saline.
摘要翻译：制备干燥的交联明胶组合物，其快速再水化以产生适合作为止血密封剂的明胶水凝胶。在某些再水化助剂如聚乙二醇，聚乙烯基丙基吡咯烷酮和葡聚糖存在下，明胶是交联的，以产生干燥的交联明胶粉末。已经发现使用再水合助剂在含水的再水合介质（通常为含有凝血酶的盐水）的存在下显着增加再水合速率。

2. 发明申请

US20080085316A1 DRY HEMOSTATIC COMPOSITIONS AND METHODS FOR THEIR PREPARATION 有权
标题翻译：干燥剂组合物及其制备方法
公开(公告)号：US20080085316A1
公开(公告)日：2008-04-10
申请号：US11859312
申请日：2007-09-21
申请人： Zhen Qian , A. Osawa , Cary Reich , Donald Wallace , Narinder Shargill , Felix Vega
发明人： Zhen Qian , A. Osawa , Cary Reich , Donald Wallace , Narinder Shargill , Felix Vega
IPC分类号： A61K9/14 , A61K47/32
CPC分类号： A61L24/0031 , A61L24/043 , A61L24/104 , A61L2400/04 , C08L89/00
摘要： Dry cross-linked gelatin compositions are prepared that rapidly re-hydrate to produce gelatin hydrogels suitable as hemostatic sealants. Gelatin is cross-linked in the presence of certain re-hydration aids, such as polyethylene glycol, polyvinylprovidone, and dextran, in order to produce a dry cross-linked gelatin powder. The use of the re-hydration aids has been found to substantially increase the re-hydration rate in the presence of an aqueous re-hydration medium, typically thrombin-containing saline.
摘要翻译：制备干燥的交联明胶组合物，其快速再水化以产生适合作为止血密封剂的明胶水凝胶。在某些再水化助剂如聚乙二醇，聚乙烯基丙基吡咯烷酮和葡聚糖存在下，明胶是交联的，以产生干燥的交联明胶粉末。已经发现使用再水合助剂在含水的再水合介质（通常为含有凝血酶的盐水）的存在下显着增加再水合速率。

3. 发明授权

US08167941B2 Intraocular, accommodating lens and methods of use 有权
标题翻译：眼内镜，适配镜片及使用方法
公开(公告)号：US08167941B2
公开(公告)日：2012-05-01
申请号：US12343406
申请日：2008-12-23
申请人： Stephen Boyd , Cary Reich
发明人： Stephen Boyd , Cary Reich
IPC分类号： A61F2/16
CPC分类号： B29D11/023 , A61F2/1635 , A61F2240/001 , B23K26/0624 , B23K2103/42 , B23K2103/50 , B29D11/00461
摘要： An intraocular lens comprises an optical element adapted to be implanted within the capsular bag of a human eye. The optical element includes one or more internal layers formed by one or more planes that are moveable relative to one another in order to effect the power of the optical element.
摘要翻译：眼内透镜包括适于植入人眼的囊袋内的光学元件。光学元件包括由相对于彼此可移动的一个或多个平面形成的一个或多个内层，以便实现光学元件的功率。

4. 发明申请

US20110276131A1 NASOLACRIMAL DRAINAGE SYSTEM IMPLANTS FOR DRUG THERAPY 有权
标题翻译：用于药物治疗的NASOLACRIMAL排水系统植入物
公开(公告)号：US20110276131A1
公开(公告)日：2011-11-10
申请号：US13184690
申请日：2011-07-18
申请人： Eugene de Juan, JR. , Stephen Boyd , Cary Reich , Alan Rapacki , Hanson S. Gifford, III , Mark Deem
发明人： Eugene de Juan, JR. , Stephen Boyd , Cary Reich , Alan Rapacki , Hanson S. Gifford, III , Mark Deem
IPC分类号： A61F2/14
CPC分类号： A61K9/0051 , A61F9/0017 , A61F9/0026 , A61F9/00772 , A61F9/00781 , A61F2220/0008 , A61F2250/0067 , A61F2250/0087 , A61K9/00 , A61K9/0017 , A61K9/06 , A61K31/215 , A61K31/216 , A61K31/55 , A61K31/557 , A61K31/5575 , A61K31/573 , A61K47/34 , A61L31/16
摘要： An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.
摘要翻译：用于插入通过泪点并进入患者的小管腔的植入物。植入物包括材料基质，分散在材料基质中的治疗剂，鞘层，其设置在材料基质的一部分上并且被配置为抑制治疗剂从材料基质释放到小管腔内，并且允许治疗剂从材料基质的表面释放到泪膜，以及构造成将植入物保持在小管腔内的保留结构。

5. 发明申请

US20090292355A1 INTRAOCULAR, ACCOMMODATING LENS AND METHODS OF USE 有权
标题翻译：内镜，镜片镜片和使用方法
公开(公告)号：US20090292355A1
公开(公告)日：2009-11-26
申请号：US12343406
申请日：2008-12-23
申请人： Stephen Boyd , Cary Reich
发明人： Stephen Boyd , Cary Reich
IPC分类号： A61F2/16
CPC分类号： B29D11/023 , A61F2/1635 , A61F2240/001 , B23K26/0624 , B23K2103/42 , B23K2103/50 , B29D11/00461
摘要： An intraocular lens comprises an optical element adapted to be implanted within the capsular bag of a human eye. The optical element includes one or more internal layers formed by one or more planes that are moveable relative to one another in order to effect the power of the optical element.
摘要翻译：眼内透镜包括适于植入人眼的囊袋内的光学元件。光学元件包括由相对于彼此可移动的一个或多个平面形成的一个或多个内层，以便实现光学元件的功率。

6. 发明授权

US6090995A Surface modifying composition and method 失效
标题翻译：表面改性组合物和方法
公开(公告)号：US6090995A
公开(公告)日：2000-07-18
申请号：US808055
申请日：1997-02-28
申请人： Cary Reich , Jeffrey Forsberg , Harold Levy , Jean Toner-Webb
发明人： Cary Reich , Jeffrey Forsberg , Harold Levy , Jean Toner-Webb
IPC分类号： A61F2/02 , A61F2/14 , A61L27/00 , A61L27/34 , B05D3/06
CPC分类号： A61F2/14 , A61L27/34
摘要： Synthetic surfaces such as surfaces of implantable prosthetic devices are modified to enhance their ability to support the growth, migration and attachment of epithelial cells. A surface modifier composition is covalently bound to the synthetic surface, and an epithelial cell-supporting coating is applied to the modified surface. The surface modifier composition may also include an epithelial cell-supporting material. The invention is particularly suited towards the modification of synthetic epikeratophakia lenses.
摘要翻译：修饰合成表面，例如可植入假体装置的表面，以增强其支持上皮细胞生长，迁移和附着的能力。表面改性剂组合物共价结合到合成表面，并且将上皮细胞支持的涂层施加到改性表面。表面改性剂组合物还可以包括上皮细胞支持材料。本发明特别适用于合成表皮假透镜透镜的修饰。

7. 发明授权

US5274028A Polyvinyl pyrrolidone-grafted coatings on preformed polymers 失效
标题翻译：聚乙烯吡咯烷酮接枝涂层在预成型聚合物上
公开(公告)号：US5274028A
公开(公告)日：1993-12-28
申请号：US622917
申请日：1990-12-06
申请人： William J. Bertrand , Stephen L. Coulter , Cary Reich , Paul DeAntonio
发明人： William J. Bertrand , Stephen L. Coulter , Cary Reich , Paul DeAntonio
IPC分类号： C08F291/00 , C08F291/18 , C08J7/16 , C08F283/00 , C08F283/12
CPC分类号： C08J7/16 , C08F291/18
摘要： In an improved method for producing a surface graft of a hydrophilic polymer upon a preformed solid or semi-solid polymer substrate having hydroperoxide groups along its surface, n-vinyl pyrrolidone is utilized as the surface-grafting monomer, the substrate is selected to be insoluble in n-vinyl pyrrolidone, and the polymerization is carried out in aqueous alkaline conditions utilizing a combination of metal salts to provide a variable valence metal ion in a reduced state capable of oxidizing to suppress homopolymerization of the monomer in the solution.When the substrate is at least partially soluble in the n-vinyl pyrrolidone, an ethylenically unsaturated monomer having a higher reactivity with the substrate than n-vinyl pyrrolidone is added to the alkaline polymerization solution as a "seeding" monomer. Addition of the "seeding" monomer results in a surface-grafted copolymer effectively externalized from the substrate.
摘要翻译：在将亲水性聚合物的表面接枝物制成在其表面具有氢过氧化物基团的预制固体或半固体聚合物基材上的改进方法中，使用N-乙烯基吡咯烷酮作为表面接枝单体，将底物选择为不溶的在乙烯基吡咯烷酮中进行聚合，并且使用金属盐的组合在水性碱性条件下进行聚合，以提供能够氧化的还原状态的可变价金属离子，以抑制溶液中单体的均聚。当底物至少部分可溶于n-乙烯基吡咯烷酮时，作为“接种”单体，向碱性聚合溶液中加入与底物比具有高于N-乙烯基吡咯烷酮的反应性更高的烯属不饱和单体。添加“接种”单体导致有效地从基底外化的表面接枝共聚物。

8. 发明授权

US5259998A Method for casting dissolvable ophthalmic shields in a mold 失效
标题翻译：在模具中铸造可溶性眼用护罩的方法
公开(公告)号：US5259998A
公开(公告)日：1993-11-09
申请号：US770867
申请日：1991-10-04
申请人： Cary Reich , Jean Toner-Webb
发明人： Cary Reich , Jean Toner-Webb
IPC分类号： B29C35/08 , B29C35/16 , B29C43/02 , B29D11/00 , G02B1/04 , B29C11/00
CPC分类号： B29D11/00096 , G02B1/043 , B29C2035/0827 , B29C2035/165 , B29C43/02 , B29K2089/00 , B29L2011/0041
摘要： A method for making a biosoluble collagen or gelatin ophthalmic shield, which optionally contains a pharmaceutically active agent, by casting collagen or gelatin in a mold; chilling the mold with the collagen or gelatin shield until the shield is strong enough to allow the mold to be opened without deforming the shield in one half of the mold; drying the collagen or gelatin shield while it is still in the mold; and then cross-linking the collagen or gelatin shield to achieve the desired solubility. The resulting shield can be worn comfortably in the eye and leaves no observable material after complete dissolution and drug release.
摘要翻译：通过在模具中浇铸胶原蛋白或明胶，制备任选含有药物活性剂的生物可溶性胶原蛋白或明胶眼科屏蔽物的方法; 用胶原蛋白或明胶屏蔽物冷却模具，直到屏蔽足够坚固，以允许模具打开而不使模具的一半中的屏蔽层变形; 干燥胶原蛋白或明胶屏蔽物，同时仍然在模具中; 然后交联胶原蛋白或明胶屏蔽以达到所需的溶解度。所得到的护罩可以舒适地佩戴在眼睛中，并且在完全溶解和药物释放之后没有观察到的材料。

9. 发明授权

US4973466A Wound-healing dressings and methods 失效
标题翻译：伤口愈合敷料和方法
公开(公告)号：US4973466A
公开(公告)日：1990-11-27
申请号：US209310
申请日：1988-06-21
申请人： Cary Reich
发明人： Cary Reich
IPC分类号： A61L26/00 , A61L31/04 , A61L31/14
CPC分类号： A61L31/047 , A61L26/0047 , A61L26/008 , A61L31/145 , Y10S514/944 , Y10S514/953 , Y10S514/954
摘要： Wound healing dressings are prepared by flocculating fibronectin, a biologically active fragment or an analog thereof to produce a water-swellable gel. The gels, in the form of sheets, strips, wedges, strands or I-shaped cross-sections, are especially useful in promoting the healing of corneal, scleral dermal, incisional wounds or lesions. They can be used to enhance the results obtained in keratorefractive surgeries and the healing scleral incision for intraocular surgery.
摘要翻译：伤口愈合敷料通过絮凝纤连蛋白，生物活性片段或其类似物制备，以产生水溶胀性凝胶。呈片状，条状，楔形，股线或I形横截面形式的凝胶特别可用于促进角膜，巩膜真皮，切口伤口或损伤的愈合。它们可用于增强角膜屈光手术和眼内手术愈合巩膜切口获得的结果。

10. 发明授权

US09050765B2 Intraocular, accommodating lens and methods of use 有权
标题翻译：眼内镜，适配镜片及使用方法
公开(公告)号：US09050765B2
公开(公告)日：2015-06-09
申请号：US13420499
申请日：2012-03-14
申请人： Stephen Boyd , Cary Reich
发明人： Stephen Boyd , Cary Reich
IPC分类号： B29D11/02 , A61F2/16 , B23K26/06 , B23K26/40 , B29D11/00
CPC分类号： B29D11/023 , A61F2/1635 , A61F2240/001 , B23K26/0624 , B23K2103/42 , B23K2103/50 , B29D11/00461
摘要： An intraocular lens comprises an optical element adapted to be implanted within the capsular bag of a human eye. The optical element includes one or more internal layers formed by one or more planes that are moveable relative to one another in order to effect the power of the optical element.
摘要翻译：眼内透镜包括适于植入人眼的囊袋内的光学元件。光学元件包括由相对于彼此可移动的一个或多个平面形成的一个或多个内层，以便实现光学元件的功率。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式