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1. 发明申请

US20100292478A1 PROCESS OF PREPARING A RADIOACTIVE COMPOUND CONTAINING A FLUORINE-18 ISOTOPE 审中-公开
标题翻译：制备含有氟-18异构体的放射性化合物的方法
公开(公告)号：US20100292478A1
公开(公告)日：2010-11-18
申请号：US12749046
申请日：2010-03-29
申请人： Zang Hee CHO , Young Bo Kim , Sang Yoon LEE , So Hee KIM
发明人： Zang Hee CHO , Young Bo Kim , Sang Yoon LEE , So Hee KIM
IPC分类号： C07D455/06 , C07D451/00 , C07D213/64 , C07D277/62 , C07C253/30 , C07C217/76 , C07C45/61
CPC分类号： C07D213/64 , C07C213/06 , C07C253/30 , C07D233/91 , C07D277/66 , C07D285/10 , C07D451/02 , C07D455/06 , C07D471/04 , C07C217/80 , C07C255/42
摘要： A process of preparing a radioactive compound containing a fluorine-18 isotope is provided. In one embodiment, the process may comprise forming a [18F] fluoroalkyl triflate by triflating a [18F] fluoroalkyl compound with AgOTf, and forming a [18F] fluoroalkylated radioactive compound through alkylation between the [18F] fluoroalkyl triflate and a radioactive compound precursor having at least one group selected from NH, OH and SH.
摘要翻译：提供了制备含有氟-18同位素的放射性化合物的方法。在一个实施方案中，该方法可以包括通过使[18 F]氟烷基化合物与AgOTf进行三氟甲酰化形成[18 F]氟烷基三氟甲磺酸酯，并通过[18 F]氟代烷基三氟甲磺酸酯与具有选自NH，OH和SH中的至少一个基团。

2. 发明申请

US20100019767A1 RF COIL ASSEMBLY FOR A MAGNETIC RESONANCE IMAGING SYSTEM 审中-公开
标题翻译：用于磁共振成像系统的RF线圈组件
公开(公告)号：US20100019767A1
公开(公告)日：2010-01-28
申请号：US12372339
申请日：2009-02-17
申请人： Zang Hee CHO , Young Bo KIM , Jae Yong HAN , Kyoung Nam KIM , Jung Hwan KIM , Suk Min HONG
发明人： Zang Hee CHO , Young Bo KIM , Jae Yong HAN , Kyoung Nam KIM , Jung Hwan KIM , Suk Min HONG
IPC分类号： G01R33/32
CPC分类号： G01R33/34046 , G01R33/34076 , G01R33/3642 , G01R33/3664 , G01R33/3678 , G01R33/5659
摘要： An RF (radio frequency) coil assembly of a magnetic resonance imaging (MRI) system, which has a spiral-shaped coil and a plurality of sections. In one embodiment, an RF coil of a magnetic resonance imaging (MRI) system has a plurality of ring-shaped end-rings arranged vertically and a plurality of rods. Each of the rods are connected to the plurality of end-rings. Adjacent end-rings of the plurality of end-rings forms respective coil sections and each of the coil sections has switching blocks located between adjacent rods of the plurality of rods. The switching blocks are operable to control the continuity status of the plurality of rods in the respective coil section.
摘要翻译：磁共振成像（MRI）系统的RF（射频）线圈组件，其具有螺旋形线圈和多个部分。在一个实施例中，磁共振成像（MRI）系统的RF线圈具有垂直布置的多个环形端环和多个杆。每个杆连接到多个端环。多个端环的相邻端环形成相应的线圈段，并且每个线圈段具有位于多个杆的相邻杆之间的切换块。切换块可操作以控制各个线圈段中的多个杆的连续性状态。

3. 发明申请

US20110196228A1 PET-MRI HYBRID APPARATUS AND METHOD OF IMPLEMENTING THE SAME 审中-公开
标题翻译： PET-MRI混合装置及其实施方法
公开(公告)号：US20110196228A1
公开(公告)日：2011-08-11
申请号：US13089548
申请日：2011-04-19
申请人： Zang Hee CHO , Young Bo KIM , Cheol Ok LEE
发明人： Zang Hee CHO , Young Bo KIM , Cheol Ok LEE
IPC分类号： A61B5/055
CPC分类号： G01R33/481 , A61B6/037 , G01R33/20 , G01R33/422 , G01T1/1603 , G01T1/2985
摘要： There is provided a PET-MRI hybrid apparatus and method for integrating a PET image and an MRI image so that anatomical, hemodynamical and molecular information on human tissues are simultaneously presented in a single image. The PET-MRI hybrid system comprises a first scanner for obtaining anatomical and hemodynamical information, and a second scanner for obtaining molecular and functional information on the human tissues. Along a path between the first scanner and the second scanner, a transferring railway system which includes runs, and a movable bed for supporting a subject installed on the railway. The PET-MRI hybrid system also comprises a “RF+magnetic” shield and a “magnetic” shield between path between the first scanner and the second scanner, which switch between an open status and a close status in a completely synchronized manner to assure a complete magnetic shield for the PET system at any given time. The subject is fastened on the bed and transferred along the railway between the first and second scanner to provide accurately fused MRI and PET images.
摘要翻译：提供了一种用于整合PET图像和MRI图像的PET-MRI混合装置和方法，使得在单个图像中同时呈现人体组织上的解剖，血液动力学和分子信息。 PET-MRI混合系统包括用于获得解剖学和血液动力学信息的第一扫描仪，以及用于在人体组织上获得分子和功能信息的第二扫描仪。沿着第一扫描器和第二扫描器之间的路径，包括运行的传送铁路系统和用于支撑安装在铁路上的物体的活动床。 PET-MRI混合系统还包括在第一扫描器和第二扫描器之间的路径之间的“RF +磁”屏蔽和“磁”屏蔽，其以完全同步的方式在打开状态和关闭状态之间切换，以确保在任何给定时间，PET系统都有完整的磁屏蔽。主体被固定在床上并沿第一和第二扫描仪之间的铁路传送，以提供精确融合的MRI和PET图像。

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