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1. 发明授权

US6113914A Osp A proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines 失效
标题翻译： Osp一种布氏疏螺旋体亚群的蛋白质，编码基因和疫苗
公开(公告)号：US6113914A
公开(公告)日：2000-09-05
申请号：US193159
申请日：1994-07-05
申请人： Yves Lobet , Markus Simon , Ulrich Schaible , Reinhard Wallich , Michael Kramer
发明人： Yves Lobet , Markus Simon , Ulrich Schaible , Reinhard Wallich , Michael Kramer
IPC分类号： A61K38/00 , A61K39/00 , A61K39/02 , A61P31/04 , C07K14/11 , C07K14/20 , C07K16/00 , C07K16/12 , C07K19/00 , C12N1/20 , C12N15/00 , C12N15/09 , C12N15/31 , C12N15/32 , C12N15/44 , C12N15/62 , C12P21/02 , C12P21/08 , C12Q1/68 , C12R1/01 , C12R1/19 , A61K39/116 , G01N33/554
CPC分类号： C07K16/1207 , C07K14/005 , C07K14/20 , C12Q1/689 , C12R1/01 , A61K38/00 , A61K39/00 , C07K2319/40 , C12N2760/16022 , Y10S530/806 , Y10S530/82 , Y10S530/825
摘要： The invention relates to novel Borrelia, and OspA antigens derived therefrom. These antigens show little homology with known OspA's and are therefore useful as vaccine and diagnostic reagents. Multicomponent vaccines based on OspA's from different Borrelia groups are also disclosed.
摘要翻译： PCT No.PCT / EP92 / 01827 Sec。 371日期：1994年7月5日 102（e）日期1994年7月5日PCT提交1992年8月11日PCT公布。公开号WO93 / 04175 日期1993年3月4日本发明涉及由其衍生的新型疏螺旋体和OspA抗原。这些抗原与已知的OspA显示出很小的同源性，因此可用作疫苗和诊断试剂。还公开了基于来自不同Borrelia组的OspA的多组分疫苗。

2. 发明授权

US5942236A Osp A proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines 失效
标题翻译： Osp一种布氏疏螺旋体亚群的蛋白质，编码基因和疫苗
公开(公告)号：US5942236A
公开(公告)日：1999-08-24
申请号：US441857
申请日：1995-05-16
申请人： Yves Lobet , Markus Simon , Ulrich Schaible , Reinhard Wallich , Michael Kramer
发明人： Yves Lobet , Markus Simon , Ulrich Schaible , Reinhard Wallich , Michael Kramer
IPC分类号： A61K38/00 , A61K39/00 , A61K39/02 , A61P31/04 , C07K14/11 , C07K14/20 , C07K16/00 , C07K16/12 , C07K19/00 , C12N1/20 , C12N15/00 , C12N15/09 , C12N15/31 , C12N15/32 , C12N15/44 , C12N15/62 , C12P21/02 , C12P21/08 , C12Q1/68 , C12R1/01 , C12R1/19 , C07K14/00
CPC分类号： C07K16/1207 , C07K14/005 , C07K14/20 , C12Q1/689 , C12R1/01 , A61K38/00 , A61K39/00 , C07K2319/40 , C12N2760/16022 , Y10S530/806 , Y10S530/82 , Y10S530/825
摘要： The invention relates to novet Borrelia, and OspA antigens derived therefrom. These antigens show little homology with known OspA's and are therefore useful as vaccine and diagnostic reagents. Multicomponent vaccines based on OspA's from different Borrelia groups are also disclosed.
摘要翻译：本发明涉及疏螺旋体和由其衍生的OspA抗原。这些抗原与已知的OspA显示出很小的同源性，因此可用作疫苗和诊断试剂。还公开了基于来自不同Borrelia组的OspA的多组分疫苗。

3. 发明授权

US06676942B1 Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines 失效
标题翻译： Osp是布氏疏螺旋体亚群的蛋白质，编码基因和疫苗
公开(公告)号：US06676942B1
公开(公告)日：2004-01-13
申请号：US09283646
申请日：1999-04-01
申请人： Yves Lobet , Markus Simon , Ulrich Schaible , Reinhard Wallich , Michael Kramer
发明人： Yves Lobet , Markus Simon , Ulrich Schaible , Reinhard Wallich , Michael Kramer
IPC分类号： A61K3902
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , C07K14/20 , C07K16/1207 , C07K2319/00 , C12N2760/16022 , C12Q1/689 , C12R1/01 , Y02A50/401 , Y02A50/57
摘要： The invention related to novel Borrelia, and OspA antigens derived therefrom. These antigens show little homology with know OspA's and are therefore useful as vaccine and diagnostic reagents. Multicomponent vaccines based on OspA's from different Borrelia groups are also disclosed.
摘要翻译：本发明涉及新型的疏螺旋体和由其衍生的OspA抗原。这些抗原与已知的OspA几乎没有同源性，因此可用作疫苗和诊断试剂。还公开了基于来自不同Borrelia组的OspA的多组分疫苗。

4. 发明申请

US20070154911A1 REGULATORY PROTEIN PKE#83 FROM HUMAN KERATINOCYTES 审中-公开
标题翻译：人类KERATINOCYTES的调节蛋白PKE＃83
公开(公告)号：US20070154911A1
公开(公告)日：2007-07-05
申请号：US11566115
申请日：2006-12-01
申请人： Michael Kramer , Michael Bechtel , Jeanette Reinartz , Birgit Schaefer , Reinhard Wallich
发明人： Michael Kramer , Michael Bechtel , Jeanette Reinartz , Birgit Schaefer , Reinhard Wallich
IPC分类号： C12Q1/68 , C07H21/04 , C12P21/06 , C07K14/78
CPC分类号： C07K16/18 , C07K14/4702
摘要： The invention relates to an isolated polypeptide which is the same as or similar to (i.e., has the same function and effect as) a protein which occurs naturally in human keratinocytes and is more strongly expressed when the keratinocytes are in their activated state. The invention also relates to an isolated nucleic acid which codes a polypeptide or protein of this type that is typical for human keratinocytes and to the use of said polypeptide and said nucleic acid for detection, especially diagnostic purposes and/or for therapeutic purposes or the use of reagents, especially recombinant vector molecules and antibodies, against molecules of this type. The inventive protein has the amino acid sequence shown in sequence protocol SEQ ID NO:3 or an allele or derivative of this amino acid sequence produced therefrom by amino acid substitution, deletion, insertion, or inversion, and the inventive nucleic acid has either the amino acid sequence shown in sequence protocol SEQ ID NO:1 or a nucleotide sequence complementary thereto or a partial sequence of one of these two nucleotide sequences or a nucleotide sequence which is completely or partially hybridizable one of these two nucleotide sequences.
摘要翻译：本发明涉及与角质形成细胞处于其活化状态时天然存在的蛋白质相同或相似（即具有与之相同的功能和作用）的分离多肽。本发明还涉及编码这种类型的多肽或蛋白质的分离的核酸，其是人角质形成细胞的典型特征，以及使用所述多肽和所述核酸进行检测，特别是诊断目的和/或用于治疗目的或使用的试剂，特别是重组载体分子和抗体。本发明的蛋白质具有序列方案SEQ ID NO：3所示的氨基酸序列或通过氨基酸取代，缺失，插入或倒位从其产生的该氨基酸序列的等位基因或衍生物，并且本发明的核酸具有氨基酸序列方案SEQ ID NO：1所示的酸序列或其互补的核苷酸序列或这两个核苷酸序列之一的部分序列或这两个核苷酸序列之一完全或部分杂交的核苷酸序列。

5. 发明申请

US20150372542A1 Variable Attractive Force Motor and Generator 审中-公开
标题翻译：可变吸力力马达和发电机
公开(公告)号：US20150372542A1
公开(公告)日：2015-12-24
申请号：US14842547
申请日：2015-09-01
申请人： Michael Kramer
发明人： Michael Kramer
IPC分类号： H02K1/06
CPC分类号： H02K1/06 , H02K1/08 , H02K7/1823 , H02K53/00 , Y10S74/09
摘要： An apparatus is disclosed for extracting electrical and mechanical energy from stored magnetic energy. The apparatus includes an axial flow turbine defined by a body having an increased magnetic density from a first exterior edge along a surface of the body to a second exterior edge. Also included is a magnetic element rotatably operable about the body of the axial flow turbine. The magnetic element is configured to cause increasingly level of the magnetic attraction from the first exterior edge to that of the second exterior edge.
摘要翻译：公开了一种用于从存储的磁能提取电和机械能的装置。该装置包括由主体限定的轴向流动涡轮机，该主体具有从主体表面的第一外部边缘到第二外部边缘的增加的磁性密度。还包括可围绕轴流涡轮机的主体可旋转地操作的磁性元件。磁性元件构造成使得从第一外部边缘到第二外部边缘的磁吸引力的增加水平。

6. 发明授权

US09124147B2 Variable attractive force motor and generator 有权
标题翻译：可变吸引力电机和发电机
公开(公告)号：US09124147B2
公开(公告)日：2015-09-01
申请号：US14630409
申请日：2015-02-24
申请人： Michael Kramer
发明人： Michael Kramer
IPC分类号： H02K21/00 , H02K1/08 , H02K7/18 , H02K53/00
CPC分类号： H02K1/06 , H02K1/08 , H02K7/1823 , H02K53/00 , Y10S74/09
摘要： An apparatus is disclosed for extracting electrical and mechanical energy from stored magnetic energy. The apparatus includes an axial flow turbine defined by a body having an increased magnetic density from a first exterior edge along a surface of the body to a second exterior edge. Also included is a magnetic element rotatably operable about the body of the axial flow turbine. The magnetic element is configured to cause increasingly level of the magnetic attraction from the first exterior edge to that of the second exterior edge.
摘要翻译：公开了一种用于从存储的磁能提取电和机械能的装置。该装置包括由主体限定的轴向流动涡轮机，该主体具有从主体表面的第一外部边缘到第二外部边缘的增加的磁性密度。还包括可围绕轴流涡轮机的主体可旋转地操作的磁性元件。磁性元件构造成使得从第一外部边缘到第二外部边缘的磁吸引力的增加水平。

7. 发明授权

US08951594B2 Cold-water soluble extruded starch product 有权
公开(公告)号：US08951594B2
公开(公告)日：2015-02-10
申请号：US13529634
申请日：2012-06-21
申请人： Lin Wang , Pete Miller , Jeff Underwood , Tonya Armstrong , Michael Kramer , Susan Freers , Roger McPherson , E. Daniel Hubbard , Terry Andren
发明人： Lin Wang , Pete Miller , Jeff Underwood , Tonya Armstrong , Michael Kramer , Susan Freers , Roger McPherson , E. Daniel Hubbard , Terry Andren
IPC分类号： A23L1/05 , A23L1/00 , A23P1/08 , C08L3/08 , C08B30/14 , C09D103/08 , C09D103/02 , E04B2/96 , C08B31/12 , A23L1/36 , C09D101/28 , C08J5/18 , C09D191/00 , E04B2/76 , C08K5/00 , E04B1/38 , E04B1/24
CPC分类号： C08L3/08 , A23L7/122 , A23L11/01 , A23L25/25 , A23L27/00 , A23P20/10 , A23P20/12 , A23V2002/00 , A61K9/286 , A61K47/36 , B29C47/0021 , B29C47/889 , B29C47/92 , B29C2947/9259 , B29C2947/92704 , B29C2947/92885 , B29C2947/92895 , C08B30/14 , C08B31/12 , C08J3/03 , C08J5/18 , C08J2301/08 , C08J2303/04 , C08K5/0016 , C09D101/284 , C09D103/02 , C09D103/08 , C09D191/00 , E04B2/767 , E04B2/96 , E04B2001/2415 , E04B2001/2439 , E04B2001/405 , C08L3/02 , C08L1/284
摘要： Disclosed is a cold-water soluble starch and a process for preparing same. Generally, the process comprises providing a hydroxyalkyl starch and applying a shearing force to the starch in an extruder in the presence of moisture, the force and the moisture each being sufficient to gelatinize at least substantially all of the granules of the starch to thereby form a sheared starch. The starch is heated to its gelatinization temperature after the starch has passed partially through the barrel of the extruder, with the moisture being maintained at a level sufficiently high to allow gelatinization but sufficiency low to protect the starch from becoming too sticky to extrude. The extruded starch product thus formed may be used in connection with a number of film-forming, coating, and other applications.

8. 发明授权

US08774069B2 Method and system for synchronized mapping of data packets in an ATSC data stream 有权
标题翻译： ATSC数据流中数据包同步映射的方法和系统
公开(公告)号：US08774069B2
公开(公告)日：2014-07-08
申请号：US12468938
申请日：2009-05-20
申请人： Norman Herzog , Jens Rusch-Ihwe , Michael Simon , Michael Kramer
发明人： Norman Herzog , Jens Rusch-Ihwe , Michael Simon , Michael Kramer
IPC分类号： H04B7/00 , H04N21/2381 , H04N21/61 , H04L27/02 , H04L1/00 , H04H20/57
CPC分类号： H04L27/02 , H04H20/57 , H04L1/0041 , H04N21/2381 , H04N21/6131
摘要： Mapping data packets of a first data stream into data fields of a second data stream at several transmitters is provided by generating a first data stream with first data packets containing data associated with stationary receivers and second data packets containing data associated with mobile receivers in a head-end, where second data packets at the start of a group of consecutively transmitted second data packets contain placeholders into which signaling information is filled. A first data stream is transmitted from the head-end to each transmitter. Each transmitter extracts signaling information from the second data packets indicating in which data slot and in which data sub-frame of a received data frame the second data packet is transferred. Each transmitter inserts synchronization data in a specific data packet in each data slot containing second data packets. The first and second data packets are mapped consecutively into the second data stream.
摘要翻译：通过产生具有第一数据分组的第一数据分组来提供第一数据流的数据分组到多个发射机的第二数据流的数据字段，第一数据分组包含与固定接收机相关联的数据和包含与头部中的移动接收机相关联的数据的第二数据分组 -end，其中在一组连续发送的第二数据分组的开始处的第二数据分组包含填充信令信息的占位符。第一数据流从头端发送到每个发射机。每个发射机从第二数据分组中提取信令信息，指示在哪个数据时隙中和在哪个数据子帧中接收数据帧的第二数据分组被传送。每个发射机在包含第二数据分组的每个数据时隙中的特定数据分组中插入同步数据。第一和第二数据包被连续地映射到第二数据流中。

9. 发明授权

US08263163B2 Cold-water soluble extruded starch product 有权
标题翻译：冷水可溶性挤出淀粉制品
公开(公告)号：US08263163B2
公开(公告)日：2012-09-11
申请号：US12764296
申请日：2010-04-21
申请人： Lin Wang , Pete Miller , Tonya Armstrong , Michael Kramer , Susan Freers , Roger McPherson , Daniel E. Hubbard , Terry Andren , Jeff Underwood
发明人： Lin Wang , Pete Miller , Tonya Armstrong , Michael Kramer , Susan Freers , Roger McPherson , Daniel E. Hubbard , Terry Andren , Jeff Underwood
IPC分类号： A23L1/05
CPC分类号： C08L3/08 , A23L7/122 , A23L11/01 , A23L25/25 , A23L27/00 , A23P20/10 , A23P20/12 , A23V2002/00 , A61K9/286 , A61K47/36 , B29C47/0021 , B29C47/889 , B29C47/92 , B29C2947/9259 , B29C2947/92704 , B29C2947/92885 , B29C2947/92895 , C08B30/14 , C08B31/12 , C08J3/03 , C08J5/18 , C08J2301/08 , C08J2303/04 , C08K5/0016 , C09D101/284 , C09D103/02 , C09D103/08 , C09D191/00 , E04B2/767 , E04B2/96 , E04B2001/2415 , E04B2001/2439 , E04B2001/405 , C08L3/02 , C08L1/284
摘要： Disclosed is a cold-water soluble starch and a process for preparing same. Generally, the process comprises providing a hydroxyalkyl starch and applying a shearing force to the starch in an extruder in the presence of moisture, the force and the moisture each being sufficient to gelatinize at least substantially all of the granules of the starch to thereby form a sheared starch. The starch is heated to its gelatinization temperature after the starch has passed partially through the barrel of the extruder, with the moisture being maintained at a level sufficiently high to allow gelatinization but sufficiency low to protect the starch from becoming too sticky to extrude. The extruded starch product thus formed may be used in connection with a number of film-forming, coating, and other applications.
摘要翻译：公开了一种冷水可溶性淀粉及其制备方法。通常，该方法包括提供羟烷基淀粉并在存在水分的情况下在挤出机中对淀粉施加剪切力，所述力和水分各自足以使至少基本上所有的淀粉颗粒胶凝，由此形成剪切淀粉。在淀粉部分地通过挤出机的筒体之后，将淀粉加热到其凝胶化温度，其中水分保持在足够高的水平以允许糊化，但足够低以保护淀粉变得太粘而不能挤出。如此形成的挤出淀粉产品可与许多成膜，涂布和其它应用相结合使用。

10. 发明申请

US20120210900A1 NON-LETHAL VARIABLE DISTANCE ELECTRONIC TIMED PAYLOAD PROJECTILE AMMUNITIONS 有权
标题翻译：非线性可变距离电子定时载荷弹道导弹
公开(公告)号：US20120210900A1
公开(公告)日：2012-08-23
申请号：US12583283
申请日：2009-08-17
申请人： Michael Kramer , Corey Rutz
发明人： Michael Kramer , Corey Rutz
IPC分类号： F42B12/46 , F42C9/00 , F42C21/00 , F42B10/44 , F42B14/02 , F42B5/02 , F42B12/02 , F42C11/00
CPC分类号： F42C17/02 , F42B12/40 , F42B12/46 , F42B12/50 , F42C11/001 , F42C11/065 , F42C17/04 , F42C19/02 , F42C19/06
摘要： A non-lethal projectile used to immobilize, impair, disorient, or distract a live target. The non-lethal projectile can also be used as a signaling device. In one embodiment, a non-lethal payload carrying projectile that is detonated at a set distance determined and set by the operator. The distance is electronically controlled and can be set in the field seconds before the projectile is fired.
摘要翻译：用于固定，损害，迷失方向或分散现场目标的非致命射弹。非致死弹丸也可以用作信号装置。在一个实施例中，一个非致命的有效载荷的载体在由操作者确定和设定的设定距离处被引爆。距离是电子控制的，可以在射弹射出之前的几秒钟内设置。

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