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1. 发明授权

US08355557B2 System and method for decomposed temporal filtering for X-ray guided intervention application 有权
标题翻译：用于X射线引导干预应用的分解时间滤波的系统和方法
公开(公告)号：US08355557B2
公开(公告)日：2013-01-15
申请号：US12571487
申请日：2009-10-01
申请人： Yunqiang Chen , Ti-chiun Chang , Tong Fang , Sandra Knoth , Stefan Böhm , Peter Durlak
发明人： Yunqiang Chen , Ti-chiun Chang , Tong Fang , Sandra Knoth , Stefan Böhm , Peter Durlak
IPC分类号： G06K9/00 , A61B6/02 , A61B6/00
CPC分类号： G06T5/50 , G06T2207/20224 , G06T2207/30041 , G06T2207/30101
摘要： A method for temporally filtering medical images during a fluoroscopy guided intervention procedure includes providing a mask image, a fluoroscopy intervention image acquired at a current time during a medical intervention procedure, forming a subtraction image by subtracting the mask image from the intervention image, calculating a motion image of a moving structure in the subtraction image, forming a residual image by subtracting the motion image from the subtraction image, temporally filtering the residual image with a filtered image from a previous time, and adding the motion image to the temporally filtered residual image.
摘要翻译：一种在荧光透视引导介入手术过程中对医学图像进行临时过滤的方法包括提供掩模图像，在医疗介入过程中当前时间获取的荧光透视干预图像，通过从干预图像中减去掩模图像形成减影图像，在减法图像中的运动结构的运动图像，通过从减法图像中减去运动图像形成残差图像，并用先前时间用滤波图像对剩余图像进行时间滤波，并将运动图像与时间滤波残差图像相加。

2. 发明申请

US20100092061A1 SYSTEM AND METHOD FOR DECOMPOSED TEMPORAL FILTERING FOR X-RAY GUIDED INTERVENTION APPLICATION 有权
标题翻译：用于X射线引导干预应用的分解时间滤波的系统和方法
公开(公告)号：US20100092061A1
公开(公告)日：2010-04-15
申请号：US12571487
申请日：2009-10-01
申请人： Yunqiang Chen , Ti-chiun Chang , Tong Fang , Sandra Knoth , Stefan Böhm , Peter Durlak
发明人： Yunqiang Chen , Ti-chiun Chang , Tong Fang , Sandra Knoth , Stefan Böhm , Peter Durlak
IPC分类号： G06K9/00
CPC分类号： G06T5/50 , G06T2207/20224 , G06T2207/30041 , G06T2207/30101
摘要： A method for temporally filtering medical images during a fluoroscopy guided intervention procedure includes providing a mask image, a fluoroscopy intervention image acquired at a current time during a medical intervention procedure, forming a subtraction image by subtracting the mask image from the intervention image, calculating a motion image of a moving structure in the subtraction image, forming a residual image by subtracting the motion image from the subtraction image, temporally filtering the residual image with a filtered image from a previous time, and adding the motion image to the temporally filtered residual image.
摘要翻译：一种在荧光透视引导介入手术过程中对医学图像进行临时过滤的方法包括提供掩模图像，在医疗介入过程中当前时间获取的荧光透视干预图像，通过从干预图像中减去掩模图像形成减影图像，在减法图像中的运动结构的运动图像，通过从减法图像中减去运动图像形成残差图像，并用先前时间用滤波图像对剩余图像进行时间滤波，并将运动图像与时间滤波残差图像相加。

3. 发明申请

US20110064285A1 SYSTEM AND METHOD FOR MULTI-IMAGE BASED STENT VISIBILITY ENHANCEMENT 有权
标题翻译：用于基于多图像的视觉可视性增强的系统和方法
公开(公告)号：US20110064285A1
公开(公告)日：2011-03-17
申请号：US12846273
申请日：2010-07-29
申请人： Yunqiang Chen , Ti-chiun Chang , Michelle Xiaohong Yan , Tong Fang , Thomas Pohl , Stefan Böhm , Peter Durlak , Markus Roßmeier
发明人： Yunqiang Chen , Ti-chiun Chang , Michelle Xiaohong Yan , Tong Fang , Thomas Pohl , Stefan Böhm , Peter Durlak , Markus Roßmeier
IPC分类号： G06K9/00
CPC分类号： G06K9/6206 , G06K2209/057 , G06T5/001 , G06T5/20 , G06T5/50 , G06T2207/10016 , G06T2207/10121 , G06T2207/30101
摘要： A method for enhancing stent visibility in digital medical images includes providing a time series of 2-dimensional (2D) images of a stent in a vessel, estimating motion of the stent in a subset of images of the time series of images, estimating motion of clutter in the subset of images, where clutter comprises anatomical structures other than the stent, estimating a clutter layer in the subset of images from the estimated clutter motion, estimating a stent layer in the subset of images from the clutter layer and the estimated clutter motion, and minimizing a functional of the estimated stent motion, the estimated stent layer, the estimated clutter motion, and the estimated clutter layer to in calculate a refined stent layer image, where the refined stent layer image has enhanced visibility of the stent.
摘要翻译：一种用于增强数字医学图像中的支架可视性的方法包括在血管中提供支架的二维（2D）图像的时间序列，估计支架在时间序列图像的图像的子集中的运动，估计运动在图像子集中混乱，其中杂波包括除了支架之外的解剖结构，从估计的杂波运动估计图像子集中的杂波层，估计来自杂波层的图像子集中的支架层和估计的杂波运动并且在计算精制的支架层图像时，将精确的支架层图像具有增强的支架的可视性，并且将估计的支架运动，估计的支架层，估计的杂波运动和估计的杂波层的功能最小化。

4. 发明授权

US08073191B2 Method and system for correcting butting artifacts in X-ray images 有权
标题翻译：用于校正X射线图像中的伪像的方法和系统
公开(公告)号：US08073191B2
公开(公告)日：2011-12-06
申请号：US12283357
申请日：2008-09-11
申请人： Ti-chiun Chang , Yunqiang Chen , Tong Fang , Sandra Martin , Stefan Böhm , Peter Durlak
发明人： Ti-chiun Chang , Yunqiang Chen , Tong Fang , Sandra Martin , Stefan Böhm , Peter Durlak
IPC分类号： G06K9/00
CPC分类号： G06K9/346 , G06K2209/05 , G06T5/005 , G06T5/20 , G06T2207/10116 , G06T2207/20012 , G06T2207/20076 , G06T2207/30004
摘要： A method and system for correcting butting artifacts in x-ray images is disclosed. In order to correct a butting artifact in an x-ray image, a butting artifact region in the x-ray image is normalized. Multiple intensity shift estimators are calculated for each pixel of each line of the butting artifact. Confidence intervals are calculated for each intensity shift estimator. A multiple hypothesis hidden Markov model (MH-HMM) is formulated based on the intensity shift operators and confidence measures subject to a smoothness constraint, and the MH-HMM is solved to determine intensity shift values for each pixel. A corrected image is generated by adjusting the intensity of each pixel of the butting artifact based on the intensity shift value for that pixel.
摘要翻译：公开了一种用于校正X射线图像中的伪像的方法和系统。为了校正X射线图像中的对接伪影，对x射线图像中的对接伪影区域进行归一化。针对对接工件的每一行的每个像素计算多个强度偏移估计量。为每个强度偏移估计器计算置信区间。基于强度偏移算子和基于平滑度约束的置信度度度，制定了多重假设隐马尔可夫模型（MH-HMM），并求解了MH-HMM，以确定每个像素的强度偏移值。通过基于该像素的强度偏移值调整对接伪影的每个像素的强度来生成校正图像。

5. 发明授权

US08433115B2 System and method for multi-image based stent visibility enhancement 有权
标题翻译：用于基于多图像的支架可见度增强的系统和方法
公开(公告)号：US08433115B2
公开(公告)日：2013-04-30
申请号：US12846273
申请日：2010-07-29
申请人： Yunqiang Chen , Ti-chiun Chang , Michelle Xiaohong Yan , Tong Fang , Thomas Pohl , Stefan Böhm , Peter Durlak , Markus Roβmeier
发明人： Yunqiang Chen , Ti-chiun Chang , Michelle Xiaohong Yan , Tong Fang , Thomas Pohl , Stefan Böhm , Peter Durlak , Markus Roβmeier
IPC分类号： G06K9/00
CPC分类号： G06K9/6206 , G06K2209/057 , G06T5/001 , G06T5/20 , G06T5/50 , G06T2207/10016 , G06T2207/10121 , G06T2207/30101
摘要： A method for enhancing stent visibility in digital medical images includes providing a time series of 2-dimensional (2D) images of a stent in a vessel, estimating motion of the stent in a subset of images of the time series of images, estimating motion of clutter in the subset of images, where clutter comprises anatomical structures other than the stent, estimating a clutter layer in the subset of images from the estimated clutter motion, estimating a stent layer in the subset of images from the clutter layer and the estimated clutter motion, and minimizing a functional of the estimated stent motion, the estimated stent layer, the estimated clutter motion, and the estimated clutter layer to in calculate a refined stent layer image, where the refined stent layer image has enhanced visibility of the stent.
摘要翻译：一种用于增强数字医学图像中的支架可视性的方法包括在血管中提供支架的二维（2D）图像的时间序列，估计支架在时间序列图像的图像的子集中的运动，估计运动在图像子集中混乱，其中杂波包括除了支架之外的解剖结构，从估计的杂波运动估计图像子集中的杂波层，估计来自杂波层的图像子集中的支架层和估计的杂波运动并且在计算精制的支架层图像时，将精确的支架层图像具有增强的支架的可视性，并且将估计的支架运动，估计的支架层，估计的杂波运动和估计的杂波层的功能最小化。

6. 发明授权

US07539336B2 X-ray diagnostic apparatus and method for operating an x-ray diagnostic apparatus for determining quality values 有权
标题翻译：用于操作用于确定质量值的X射线诊断装置的X射线诊断装置和方法
公开(公告)号：US07539336B2
公开(公告)日：2009-05-26
申请号：US11293444
申请日：2005-12-02
申请人： Stefan Böhm , Peter Durlak , Volker Heer , Martin Kolarjk
发明人： Stefan Böhm , Peter Durlak , Volker Heer , Martin Kolarjk
IPC分类号： G06K9/00
CPC分类号： G06T7/0002 , A61B6/504 , A61B6/583 , H04N5/325 , Y10S128/922
摘要： The invention relates to an angiographic x-ray diagnostic apparatus with an x-ray radiator having an x-ray tube, with a patient positioning table having a radiation-transparent positioning plate and mattress, with an x-ray detector, with an imaging system, an image processing unit and a measuring device to which the output signals of the x-ray detector are fed and which has a first device for determining a value determining the reproduction quality of clinically relevant objects, a second device for determining local variances of the noise in a homogenous image region of different x-ray images and a device for taking the ratio of the output values of the two devices.
摘要翻译：本发明涉及具有x射线管的x射线辐射器的血管造影X射线诊断装置，其中患者定位台具有辐射透明的定位板和床垫，具有x射线检测器，具有成像系统，图像处理单元和测量装置，X射线检测器的输出信号被馈送到该图像处理单元和测量装置，并且具有用于确定确定临床相关对象的再现质量的值的第一装置，用于确定临床相关对象的再现质量的第二装置，在不同X射线图像的均匀图像区域中的噪声和用于获取两个装置的输出值的比率的装置。

7. 发明授权

US08355550B2 Methods and apparatus for virtual coronary mapping 有权
标题翻译：虚拟冠状动脉成像的方法和装置
公开(公告)号：US08355550B2
公开(公告)日：2013-01-15
申请号：US12150816
申请日：2008-05-01
申请人： Wei Zhang , Ying Zhu , Adrian Barbu , Richard Socher , Stefan Böhm , Peter Durlak , Dorin Comaniciu
发明人： Wei Zhang , Ying Zhu , Adrian Barbu , Richard Socher , Stefan Böhm , Peter Durlak , Dorin Comaniciu
IPC分类号： G06K9/00
CPC分类号： G06K9/3216 , A61B6/12 , A61B6/481 , A61B6/504 , G06K2009/00932 , G06K2209/05 , G06T7/12 , G06T2207/20044 , G06T2207/30101 , G06T2207/30172
摘要： A virtual map of vessels of interest in medical procedures, such as coronary angioplasty is created so that doses of contrasting agent given to a patient may be reduced. A position of a coronary guidewire is determined and locations of vessel boundaries are found. When the contrast agent has dissipated, virtual maps of the vessels are created as new images. The locations of the determined vessel boundaries are imported to a mapping system and an image obtained without using a contrast agent is modified based on the imported locations of vessel boundaries. This creates a virtual map of the vessels.
摘要翻译：创建医疗程序感兴趣的血管的虚拟地图，例如冠状动脉血管成形术，以便减少给予患者的剂量的造影剂。确定冠状导丝的位置并找到血管边界的位置。当造影剂消散时，血管的虚拟地图被创建为新的图像。确定的容器边界的位置被导入到映射系统，并且基于导入的容器边界的位置来修改不使用造影剂获得的图像。这将创建一个血管的虚拟地图。

8. 发明授权

US07826651B2 Method for operating an x-ray diagnostic apparatus for determining quality values 有权
标题翻译：用于操作用于确定质量值的x射线诊断装置的方法
公开(公告)号：US07826651B2
公开(公告)日：2010-11-02
申请号：US12401295
申请日：2009-03-10
申请人： Stefan Böhm , Peter Durlak , Volker Heer , Martin Kolarjk
发明人： Stefan Böhm , Peter Durlak , Volker Heer , Martin Kolarjk
IPC分类号： G06K9/00
CPC分类号： G06T7/0002 , A61B6/504 , A61B6/583 , H04N5/325 , Y10S128/922
摘要： A method for checking an x-ray diagnostic apparatus is provided. Fluoroscopic series of x-ray images of a technical phantom are digitally acquired and stored. Difference between a dynamic image and a background image is calculated. A measuring field is predicted. Priori information about the shape of a clinically relevant object is determined. Hough transformation on a gray value image corresponding to the difference is applied. Contrast of the object from the Hough-transformed gray value image is determined. A square of the determined contrast is calculated. A noise variance is calculated by determining a sum of a noise variance of a homogenous image region and a variance of the background image. A contrast-to-noise ratio of the determined contrast and the calculated noise variance is determined. A square of the contrast-to-noise ratio is dynamically averaged. A Clinical Relevant Fluoroscopy Performance index for the x-ray diagnostic apparatus is determined.
摘要翻译：提供了一种用于检查x射线诊断装置的方法。数字获取和存储技术幻像的荧光系列X射线图像。计算动态图像和背景图像之间的差异。预测测量场。确定关于临床相关对象的形状的优先信息。应用与差异对应的灰度值图像上的霍夫变换。确定来自霍夫变换灰度值图像的对象的对比度。计算确定的对比度的平方。通过确定均匀图像区域的噪声方差和背景图像的方差的和来计算噪声方差。确定所确定的对比度和所计算的噪声方差的对比噪声比。动态平均对比噪声比的平方。确定X线诊断仪的临床相关荧光检查性能指标。

9. 发明授权

US08126248B2 Procedures for the presentation of medical images 有权
标题翻译：介绍医学图像的程序
公开(公告)号：US08126248B2
公开(公告)日：2012-02-28
申请号：US12284979
申请日：2008-09-26
申请人： Stefan Böhm , Peter Durlak , Boris Stowasser
发明人： Stefan Böhm , Peter Durlak , Boris Stowasser
IPC分类号： G06K9/00
CPC分类号： G01N23/04 , A61B6/583 , A61B6/585 , G06K9/40 , G06T5/002 , G06T5/10 , G06T5/50 , G06T11/005 , G06T2207/10081 , G06T2207/10116 , G06T2207/20064 , G06T2207/30004
摘要： The invention relates to a method for presentation of medical images by a reproduction facility of a diagnostic device with suppression of the noise with the following steps: one-off calibration of the signal-dependent noise; separation of the signal and noise components in the image; adaptation of the two components according to set parameters; and composition of the signals.
摘要翻译：本发明涉及一种用于通过具有抑制噪声的诊断装置的再现设施呈现医学图像的方法，其具有以下步骤：信号相关噪声的一次性校准; 分离图像中的信号和噪声分量; 根据设定参数对两个部件进行调整; 和信号的组成。

10. 发明授权

US08121367B2 Method and system for vessel segmentation in fluoroscopic images 有权
标题翻译：荧光镜图像中血管分割的方法和系统
公开(公告)号：US08121367B2
公开(公告)日：2012-02-21
申请号：US12229663
申请日：2008-08-26
申请人： Richard Socher , Adrian Barbu , Bogdan Georgescu , Wei Zhang , Peter Durlak , Stefan Böhm , Dorin Comaniciu
发明人： Richard Socher , Adrian Barbu , Bogdan Georgescu , Wei Zhang , Peter Durlak , Stefan Böhm , Dorin Comaniciu
IPC分类号： G06K9/00
CPC分类号： G06K9/6256 , G06K2009/00932 , G06T7/12 , G06T7/162 , G06T2207/10121 , G06T2207/30048 , G06T2207/30101
摘要： A method and system for vessel segmentation in fluoroscopic images is disclosed. Hierarchical learning-based detection is used to perform the vessel segmentation. A boundary classifier is trained and used to detect boundary pixels of a vessel in a fluoroscopic image. A cross-segment classifier is trained and used to detect cross-segments connecting the boundary pixels. A quadrilateral classifier is trained and used to detect quadrilaterals connecting the cross segments. Dynamic programming is then used to combine the quadrilaterals to generate a tubular structure representing the vessel.
摘要翻译：公开了一种用于荧光镜图像中血管分割的方法和系统。使用基于层次学习的检测来执行血管分割。边界分类器被训练并用于检测透视图像中血管的边界像素。训练跨段分类器，用于检测连接边界像素的交叉段。四边形分类器被训练并用于检测连接横截面的四边形。然后使用动态规划来组合四边形以产生代表该容器的管状结构。

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