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1. 发明授权

US06562954B1 Method for producing oligosaccharide, and novel oligosaccharide and pharmaceutical composition containing the same 有权
标题翻译：低聚糖的制造方法，新型低聚糖及含有该寡糖的药物组合物
公开(公告)号：US06562954B1
公开(公告)日：2003-05-13
申请号：US09478025
申请日：2000-01-05
申请人： Yuji Matsuzaki , Yousuke Yasuda , Satoshi Miyauchi , Junichi Onaya , Yusuke Hori , Akira Tawada , Hideo Mochizuki , Masami Iida
发明人： Yuji Matsuzaki , Yousuke Yasuda , Satoshi Miyauchi , Junichi Onaya , Yusuke Hori , Akira Tawada , Hideo Mochizuki , Masami Iida
IPC分类号： C07H1702
CPC分类号： C07H11/00 , Y02P20/55
摘要： Oligosaccharides including those usable as anti-inflammatory agent or anti-allergy agent, represented by the following general formula (3): wherein R10 and R11 each independently represent a hydrogen atom or —SO3M where M represents a proton or a monovalent cation, Ac represents an acetyl group, R12 represents a hydrogen atom or an anomeric substituent (a 6-O-sulfated N-acetylglucosamine residue, an alkyl group, a glycerol residue, an O-alkylglycerol residue, a cholesterol residue, a cholestanyl group, a ceramide residue, a phospholipid residue, a biotin residue, or a peptide residue), and Z represents an oxygen atom or —NHCO—.
摘要翻译：包括可用作抗炎剂或抗过敏剂的寡糖，由以下通式（3）表示：其中R10和R11各自独立地表示氢原子或-SO3M，其中M表示质子或一价阳离子，Ac表示乙酰基，R 12表示氢原子或端基异构取代基（6-O-硫酸化N-乙酰葡糖胺残基，烷基，甘油残基，O-烷基甘油残基，胆固醇残基，胆甾烷基，神经酰胺残基，磷脂残基，生物素残基或肽残基），Z表示氧原子或-NHCO-。

2. 发明授权

US08359490B2 Memory controller, system including the controller, and memory delay amount control method 失效
标题翻译：存储器控制器，包括控制器的系统和存储器延迟量控制方法
公开(公告)号：US08359490B2
公开(公告)日：2013-01-22
申请号：US13462689
申请日：2012-05-02
申请人： Hideo Mochizuki , Kazuaki Masuda
发明人： Hideo Mochizuki , Kazuaki Masuda
IPC分类号： G06F1/12
CPC分类号： G11C5/14 , G06F13/1689 , Y02D10/14
摘要： A memory controller coupled to a DRAM includes a delay control section including a delay holding section, and coupled to the DRAM to output a delay set value to the DRAM and a delay adjustment section coupled to the DRAM to receive data from the DRAM, and to arrange a delay amount of the received data based on the delay set value. The delay set value is stored in both the delay holding section of the memory controller and the DRAM.
摘要翻译：耦合到DRAM的存储器控制器包括延迟控制部分，该延迟控制部分包括延迟保持部分，并且耦合到DRAM以向DRAM提供延迟设置值，以及延迟调整部分，其耦合到DRAM以从DRAM接收数据，以及基于延迟设定值排列接收到的数据的延迟量。延迟设定值存储在存储器控制器的延迟保持部分和DRAM中。

3. 发明申请

US20090292940A1 Memory controller, system including the controller, and memory delay amount control method 失效
标题翻译：存储器控制器，包括控制器的系统和存储器延迟量控制方法
公开(公告)号：US20090292940A1
公开(公告)日：2009-11-26
申请号：US12453553
申请日：2009-05-14
申请人： Hideo Mochizuki , Kazuaki Masuda
发明人： Hideo Mochizuki , Kazuaki Masuda
IPC分类号： G06F12/00 , G06F1/08
CPC分类号： G11C5/14 , G06F13/1689 , Y02D10/14
摘要： A memory controller transmits and receives data to and from a memory. The memory controller includes a delay control section deciding a set value indicative of a determined delay amount in response to a result of a comparison between a test data transmitted to the memory and test data received from the memory, and transmitting the decided set value to the memory, a taking-in section receiving the set value stored in the memory, and a delay adjustment section receiving data from the memory, and arranging a delay amount of the received data in response to the set value received by the taking-in section.
摘要翻译：存储器控制器向存储器发送数据和从存储器接收数据。存储器控制器包括响应于发送到存储器的测试数据与从存储器接收的测试数据之间的比较的结果而确定指示所确定的延迟量的设定值的延迟控制部分，并将所确定的设定值发送到存储器，接收存储在存储器中的设定值的接收部分，以及从存储器接收数据的延迟调整部分，并且响应于由接收部分接收的设定值来布置接收到的数据的延迟量。

4. 发明授权

US08623625B2 Sulfotransferase, peptide thereof and DNA encoding the same 有权
标题翻译：磺酰转移酶，其肽及其编码的DNA
公开(公告)号：US08623625B2
公开(公告)日：2014-01-07
申请号：US11748403
申请日：2007-05-14
申请人： Hisashi Narimatsu , Shigemi Sugioka , Hideo Mochizuki
发明人： Hisashi Narimatsu , Shigemi Sugioka , Hideo Mochizuki
IPC分类号： C12N9/10 , C12N15/00 , C12N1/20 , C12P21/06 , C12P19/28 , C07H21/04
CPC分类号： C12N9/13
摘要： A glycosaminoglycan sulfotransferase, a peptide thereof, a nucleic acid comprising a nucleotide sequence encoding the same, an enzyme agent for the synthesis of a glycosaminoglycan, which comprises the above-described enzyme or polypeptide, and a process for producing a glycosaminoglycan, which uses the enzyme agent.
摘要翻译：糖胺聚糖磺基转移酶，其肽，包含其编码的核苷酸序列的核酸，用于合成糖胺聚糖的酶试剂，其包含上述酶或多肽，以及制备糖胺聚糖的方法，其使用酶剂。

5. 发明申请

US20090138767A1 Self-diagnostic circuit and self-diagnostic method for detecting errors 失效
标题翻译：自诊断电路和自诊断方法检测误差
公开(公告)号：US20090138767A1
公开(公告)日：2009-05-28
申请号：US12292862
申请日：2008-11-26
申请人： Hideo Mochizuki
发明人： Hideo Mochizuki
IPC分类号： G06F11/00
CPC分类号： G01R31/31704 , G01R31/317
摘要： A self-diagnostic circuit includes a setting unit receiving a plurality of detection signals generated in an integrated circuit device, and determining a type of detection signal to be detected among the received plurality of detection signals. A counter is coupled to the setting unit and counts a number of a signal corresponding to the type of the detection signal to be detected.
摘要翻译：自诊断电路包括：接收在集成电路装置中产生的多个检测信号的设定单元，以及确定接收到的多个检测信号中要检测的检测信号的种类。计数器耦合到设置单元并对与要检测的检测信号的类型相对应的信号的数量进行计数。

6. 发明申请

US20050112727A1 Sulfotransferase, its polypeptide and dna encoding the same 有权
标题翻译：磺酰转移酶，其多肽和dna编码相同
公开(公告)号：US20050112727A1
公开(公告)日：2005-05-26
申请号：US10506548
申请日：2003-03-04
申请人： Hisashi Narimatsu , Shigemi Sugioka , Hideo Mochizuki
发明人： Hisashi Narimatsu , Shigemi Sugioka , Hideo Mochizuki
IPC分类号： C12N9/10 , C12N15/54 , C08B37/10 , C07H21/04 , C12P19/28
CPC分类号： C12N9/13
摘要： A glycosaminoglycan sulfotransferase, a peptide thereof, a nucleic acid comprising a nucleotide sequence encoding the same, an enzyme agent for the synthesis of a glycosaminoglycan, which comprises the above-described enzyme or polypeptide, and a process for producing a glycosaminoglycan, which uses the enzyme agent.
摘要翻译：糖胺聚糖磺基转移酶，其肽，包含其编码的核苷酸序列的核酸，用于合成糖胺聚糖的酶试剂，其包含上述酶或多肽，以及制备糖胺聚糖的方法，其使用酶剂。

7. 发明授权

US5496718A Chondroitinase ABC isolated from proteus vulgaris ATCC 6896 失效
标题翻译：从普通寻常型ATCC 6896中分离的软骨素酶ABC
公开(公告)号：US5496718A
公开(公告)日：1996-03-05
申请号：US082853
申请日：1993-06-23
申请人： Nobukazu Hashimoto , Hideo Mochizuki , Akio Hamai
发明人： Nobukazu Hashimoto , Hideo Mochizuki , Akio Hamai
IPC分类号： A61K38/43 , A61K38/00 , C12N9/16 , C12N9/20 , C12N9/88 , C01G17/04 , C12N1/12
CPC分类号： C12N9/88 , A61K38/00 , G03C2001/0471 , Y10S435/873
摘要： A crystallizable, purified chondroitinase ABC having a molecular weight of about 100,000 dalton by the measurement of the SDS-polyacrylamide gel electrophoresis (SDS-PAGE) and the measurement by the gel permeation chromatography method, having alanine as the N-terminal amino acid and proline as the C-terminal amino acid. A process for the purification of the crystallizable purified chondroitinase ABC comprising removing nucleic acid from an surfactant solution extract obtained from cells of chondroitinase ABC-producing microorganisms and chromatographically treating by concentration gradient elution using a weak cation exchange resin or a strong cation exchange resin. A composition comprising a chondroitinase and serum albumin, gelatin, or a nonionic surfactant. The chondroitinase ABC is isolated from Proteus vulgaris ATCC 6896.
摘要翻译：通过SDS-聚丙烯酰胺凝胶电泳（SDS-PAGE）的测量和通过凝胶渗透色谱法测定的具有约100,000道尔顿分子量的可结晶纯化的软骨素酶ABC，其具有丙氨酸作为N-末端氨基酸和脯氨酸作为C末端氨基酸。一种用于纯化可结晶的纯化软骨素酶ABC的方法，包括从获自软骨素酶ABC微生物的细胞获得的表面活性剂溶液提取物中除去核酸，并使用弱阳离子交换树脂或强阳离子交换树脂进行色谱法处理。包含软骨素酶和血清白蛋白，明胶或非离子表面活性剂的组合物。软骨素酶ABC从普通变形杆菌ATCC 6896中分离。

8. 发明授权

US08315109B2 Memory interface circuit and semiconductor device 失效
标题翻译：存储器接口电路和半导体器件
公开(公告)号：US08315109B2
公开(公告)日：2012-11-20
申请号：US13272856
申请日：2011-10-13
申请人： Hideo Mochizuki
发明人： Hideo Mochizuki
IPC分类号： G11C7/10
CPC分类号： G11C7/10 , G06F13/1673 , G06F13/1689
摘要： There is a need to provide a small-sized memory interface circuit capable of adjusting timing between a strobe signal and a data signal without interrupting a normal memory access.An expected value acquisition latch latches write data in synchronization with a clock signal. A WDLL outputs a write strobe signal WDQS. An RDLL outputs a delayed write strobe signal WDQS_d. A read data latch latches looped-back write data in synchronization with the delayed write strobe signal WDQS_d. A comparator compares the read data latch with an output from the expected value acquisition latch. A register portion stores a delay value to be placed in the RDLL. A register control portion updates a delay value in the register portion in accordance with a comparison result. A delay selection portion places a delay value read from the register portion in the RDLL.
摘要翻译：需要提供能够调整选通信号和数据信号之间的定时的小型存储器接口电路，而不中断正常的存储器访问。期望值采集锁存器与时钟信号同步地锁存写入数据。 WDLL输出写选通信号WDQS。 RDLL输出延迟的写选通信号WDQS_d。读取数据锁存器与延迟写入选通信号WDQS_d同步地锁存环回写入数据。比较器将读取的数据锁存器与期望值采集锁存器的输出进行比较。寄存器部分存储要放置在RDLL中的延迟值。寄存器控制部分根据比较结果更新寄存器部分中的延迟值。延迟选择部分将从寄存器部分读取的延迟值放在RDLL中。

9. 发明授权

US08201013B2 Memory controller, system including the controller, and memory delay amount control method 失效
标题翻译：存储器控制器，包括控制器的系统和存储器延迟量控制方法
公开(公告)号：US08201013B2
公开(公告)日：2012-06-12
申请号：US12453553
申请日：2009-05-14
申请人： Hideo Mochizuki , Kazuaki Masuda
发明人： Hideo Mochizuki , Kazuaki Masuda
IPC分类号： G06F1/12
CPC分类号： G11C5/14 , G06F13/1689 , Y02D10/14
摘要： A memory controller transmits and receives data to and from a memory. The memory controller includes a delay control section deciding a set value indicative of a determined delay amount in response to a result of a comparison between a test data transmitted to the memory and test data received from the memory, and transmitting the decided set value to the memory, a taking-in section receiving the set value stored in the memory, and a delay adjustment section receiving data from the memory, and arranging a delay amount of the received data in response to the set value received by the taking-in section.
摘要翻译：存储器控制器向存储器发送数据和从存储器接收数据。存储器控制器包括响应于发送到存储器的测试数据与从存储器接收的测试数据之间的比较的结果而确定指示所确定的延迟量的设定值的延迟控制部分，并将所确定的设定值发送到存储器，接收存储在存储器中的设定值的接收部分，以及从存储器接收数据的延迟调整部分，并且响应于由接收部分接收的设定值来布置接收到的数据的延迟量。

10. 发明授权

US06184023B2 Chondroitinase, process for preparing the same, and pharmaceutical composition comprising the same 失效
标题翻译：软骨素酶，其制备方法和包含其的药物组合物
公开(公告)号：US06184023B2
公开(公告)日：2001-02-06
申请号：US08888530
申请日：1997-07-07
申请人： Nobukazu Hashimoto , Hideo Mochizuki , Akio Hamai
发明人： Nobukazu Hashimoto , Hideo Mochizuki , Akio Hamai
IPC分类号： C12N988
CPC分类号： C12N9/88 , A61K38/00 , G03C2001/0471 , Y10S435/873
摘要： A crystallizable, purified chondroitinase ABC having a molecular weight of about 100,000 dalton by the measurement of the SDS-polyacrylamide gel electrophoresis (SDS-PAGE) and the measurement by the gel permeation chromatography method, having alanine as the N-terminal amino acid and proline as the C-terminal amino acid. A process for the purification of the crystallizable purified chondroitinase ABC comprising removing nucleic acid from an surfactant solution extract obtained from cells of chondroitinase ABC-producing microorganisms and chromatographically treating by concentration gradient elution using a weak cation exchange resin or a strong cation exchange resin. A composition comprising a chondroitinase and serum albumin, gelatin, or a nonionic surfactant.
摘要翻译：通过SDS-聚丙烯酰胺凝胶电泳（SDS-PAGE）的测量和通过凝胶渗透色谱法测定的具有约100,000道尔顿分子量的可结晶纯化的软骨素酶ABC，其具有丙氨酸作为N-末端氨基酸和脯氨酸作为C末端氨基酸。一种用于纯化可结晶的纯化软骨素酶ABC的方法，包括从获自软骨素酶ABC微生物的细胞获得的表面活性剂溶液提取物中除去核酸，并使用弱阳离子交换树脂或强阳离子交换树脂进行色谱法处理。包含软骨素酶和血清白蛋白，明胶或非离子表面活性剂的组合物。

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