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1. 发明授权

US09327140B2 Beam data processing apparatus and particle beam therapy system 有权
标题翻译：光束数据处理装置和粒子束治疗系统
公开(公告)号：US09327140B2
公开(公告)日：2016-05-03
申请号：US14115028
申请日：2011-08-23
申请人： Taizo Honda , Yuichi Yamamoto , Yuehu Pu
发明人： Taizo Honda , Yuichi Yamamoto , Yuehu Pu
IPC分类号： G01K1/08 , A61N5/10 , G21K5/04
CPC分类号： A61N5/1048 , A61N5/1043 , A61N5/1075 , A61N5/1077 , A61N2005/1074 , A61N2005/1087 , G21K5/04
摘要： A beam data processing apparatus has a plurality of channel data conversion units that convert a plurality of analogue signals outputted from a position monitor into digital signals, a position size processing unit that calculates a beam position, based on voltage information items obtained through processing by the plurality of channel data conversion units, an abnormality determination processing unit that determines the beam position and generates a position abnormality signal, and an integrated control unit that controls the plurality of channel data conversion units in such a way that while a beam is stopped at an irradiation spot, digital signal conversion processing is implemented two or more times; the channel data conversion unit has a plurality of A/D converters, a demultiplexer that distributes analogue signals, and a multiplexer that switches respective digital signals processed by the A/D converters so as to output them to the position size processing unit.
摘要翻译：波束数据处理装置具有多个通道数据转换单元，其将从位置监视器输出的多个模拟信号转换为数字信号，位置大小处理单元，基于通过处理所获得的电压信息项，计算波束位置多个通道数据转换单元，确定光束位置并产生位置异常信号的异常判定处理单元，以及控制多个通道数据转换单元的集成控制单元，使得当光束停止在照射点，数字信号转换处理两次以上; 信道数据转换单元具有多个A / D转换器，分配模拟信号的多路分解器和切换由A / D转换器处理的各个数字信号的多路复用器，以便将它们输出到位置大小处理单元。

2. 发明申请

US20140228615A1 PARTICLE BEAM IRRADIATION APPARATUS AND PARTICLE BEAM THERAPY SYSTEM 有权
标题翻译：颗粒光束辐射装置和颗粒束治疗系统
公开(公告)号：US20140228615A1
公开(公告)日：2014-08-14
申请号：US14240650
申请日：2011-11-03
申请人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
发明人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
IPC分类号： A61N5/10
CPC分类号： A61N5/1081 , A61N5/1077 , A61N2005/1087 , A61N2005/1095
摘要： A particle beam irradiation apparatus according to the present invention is provided with a vacuum duct that forms a vacuum region through which the charged particle beam passes, a vacuum window through which the charged particle beam is launched from the vacuum region, a scanning electromagnet that scans the charged particle beam; a monitoring apparatus including a position monitor that detects the passing position of a charged particle beam and the beam size thereof, a low-scattering gas filling chamber including the monitoring apparatus, and an irradiation management apparatus that controls irradiation of the charged particle beam; the particle beam irradiation apparatus is characterized in that the low-scattering gas filling chamber is changeably disposed in such a manner that the beam-axis-direction positional relationship between the monitoring apparatus and the vacuum window is a desired one and in that the low-scattering gas filling chamber is filled with a low-scattering gas.
摘要翻译：根据本发明的粒子束照射装置设置有真空管道，该真空管道形成带电粒子束通过的真空区域，从真空区域发射带电粒子束的真空窗口，扫描的扫描电磁体带电粒子束; 监视装置，其包括检测带电粒子束的通过位置的位置监视器及其光束尺寸，包括监视装置的低散射气体填充室以及控制带电粒子束的照射的照射管理装置; 所述粒子束照射装置的特征在于，所述低散射气体充填室可变地设置成使得所述监视装置和所述真空窗口之间的射束轴向位置关系是期望的，散射气体填充室填充有低散射气体。

3. 发明申请

US20140187847A1 PARTICLE BEAM THERAPY SYSTEM 有权
标题翻译：颗粒束治疗系统
公开(公告)号：US20140187847A1
公开(公告)日：2014-07-03
申请号：US14240197
申请日：2011-11-02
申请人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
发明人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
IPC分类号： A61N5/10
CPC分类号： A61N5/1077 , A61N5/1049 , A61N5/1069 , A61N2005/1087
摘要： A particle beam therapy system comprising a treatment table, a treatment table control unit and an irradiation control unit configured to output an instruction for controlling the treatment table control unit, an accelerator and a scanning electromagnet, wherein after the treatment table control unit controls the treatment table so as for a patient isocenter which is reference position of an affected area of a patient to move to a position of an irradiation isocenter which is set at a position which is closer to an irradiation nozzle than an equipment isocenter which is reference of positional relation of the irradiation nozzle and the treatment table, the irradiation control unit outputs an instruction for irradiating the patient with a particle beam.
摘要翻译：一种粒子束治疗系统，包括治疗台，治疗台控制单元和照射控制单元，其被配置为输出用于控制治疗台控制单元的指令，加速器和扫描电磁体，其中在治疗台控制单元控制治疗将患者的中心位置作为患者的受影响区域的基准位置移动到被设定在比作为位置关系的参照的设备等角点更靠近照射喷嘴的位置的照射等角点的位置的照射喷嘴和处理台，照射控制单元输出用于对粒子束照射患者的指示。

4. 发明申请

US20140061498A1 BEAM DATA PROCESSING APPARATUS AND PARTICLE BEAM THERAPY SYSTEM 有权
标题翻译：光束数据处理装置和粒子束治疗系统
公开(公告)号：US20140061498A1
公开(公告)日：2014-03-06
申请号：US14115028
申请日：2011-08-23
申请人： Taizo Honda , Yuichi Yamamoto , Yuehu Pu
发明人： Taizo Honda , Yuichi Yamamoto , Yuehu Pu
IPC分类号： A61N5/10
CPC分类号： A61N5/1048 , A61N5/1043 , A61N5/1075 , A61N5/1077 , A61N2005/1074 , A61N2005/1087 , G21K5/04
摘要： A beam data processing apparatus has a plurality of channel data conversion units that convert a plurality of analogue signals outputted from a position monitor into digital signals, a position size processing unit that calculates a beam position, based on voltage information items obtained through processing by the plurality of channel data conversion units, an abnormality determination processing unit that determines the beam position and generates a position abnormality signal, and an integrated control unit that controls the plurality of channel data conversion units in such a way that while a beam is stopped at an irradiation spot, digital signal conversion processing is implemented two or more times; the channel data conversion unit has a plurality of A/D converters, a demultiplexer that distributes analogue signals, and a multiplexer that switches respective digital signals processed by the ND converters so as to output them to the position size processing unit.
摘要翻译：波束数据处理装置具有多个通道数据转换单元，其将从位置监视器输出的多个模拟信号转换为数字信号，位置大小处理单元，基于通过处理所获得的电压信息项，计算波束位置多个通道数据转换单元，确定光束位置并产生位置异常信号的异常判定处理单元，以及控制多个通道数据转换单元的集成控制单元，使得当光束停止在照射点，数字信号转换处理两次以上; 信道数据转换单元具有多个A / D转换器，分配模拟信号的多路分解器，以及多路复用器，其切换由ND转换器处理的各个数字信号，以将其输出到位置大小处理单元。

5. 发明申请

US20130320245A1 PARTICLE-BEAM ENERGY CHANGING APPARATUS, PARTICLE BEAM THERAPY SYSTEM INCLUDING THE SAME, AND METHOD OF CHANGING PARTICLE BEAM ENERGY 有权
标题翻译：颗粒束能量变化装置，包括其的颗粒束治疗系统和改变颗粒束能量的方法
公开(公告)号：US20130320245A1
公开(公告)日：2013-12-05
申请号：US13985759
申请日：2011-04-25
申请人： Yuehu Pu , Taizo Honda , Takaaki Iwata
发明人： Yuehu Pu , Taizo Honda , Takaaki Iwata
IPC分类号： A61N5/10
CPC分类号： A61N5/1048 , A61N5/1042 , A61N2005/1087 , A61N2005/1095 , G21K1/10
摘要： There is provided a particle-beam energy changing apparatus that is capable of changing energy of a particle beam quickly and silently, in which a first energy changing unit and a second energy changing unit for changing energy of a particle beam passing therethrough by varying thicknesses of their attenuators attenuating the particle beam energy are arranged so that the particle beam passes through the first energy changing unit and the second energy changing unit; and the maximum attenuation amount by the first energy changing unit is set smaller than the maximum attenuation amount by the second energy changing unit.
摘要翻译：提供了一种能够快速且静默地改变粒子束能量的粒子束能量改变装置，其中第一能量改变单元和第二能量改变单元用于通过改变粒子束的厚度来改变通过其的粒子束的能量其衰减粒子束能量的衰减器被布置成使得粒子束通过第一能量改变单元和第二能量改变单元; 并且第一能量改变单元的最大衰减量被设定为小于第二能量变化单元的最大衰减量。

6. 发明申请

US20100288946A1 CHARGED PARTICLE BEAM IRRADIATION APPARATUS 有权
标题翻译：充电颗粒光束辐射装置
公开(公告)号：US20100288946A1
公开(公告)日：2010-11-18
申请号：US12812486
申请日：2008-05-12
申请人： Taizo Honda , Hisashi Harada , Yuehu Pu
发明人： Taizo Honda , Hisashi Harada , Yuehu Pu
IPC分类号： A61N5/10
CPC分类号： A61N5/10 , A61N2005/1087 , A61N2005/1095
摘要： In a charged particle beam irradiation apparatus to be adapted to a particle beam cancer treatment system or the like, a desired depth dose distribution is highly precisely created. In the charged particle beam irradiation apparatus that irradiates a particle beam, which is radiated from a particle beam generation unit, to a subject to be irradiated via a ridge filter exhibiting a cyclic thickness distribution for causing the particle beam to exhibit a desired energy distribution, the ridge filter has plural ridges thereof arranged to be perpendicular to entering directions of the particle beam.
摘要翻译：在适用于粒子束癌治疗系统等的带电粒子束照射装置中，高度精确地产生期望的深度剂量分布。在从粒子束发生单元照射粒子束的带电粒子束照射装置中，通过使粒子束呈现期望的能量分布的具有循环厚度分布的脊形过滤器照射到被照射对象，脊状过滤器具有多个脊，其布置成垂直于粒子束的进入方向。

7. 发明授权

US06034377A Charged particle beam irradiation apparatus and method of irradiation with charged particle beam 失效
标题翻译：带电粒子束照射装置及带电粒子束照射的方法
公开(公告)号：US06034377A
公开(公告)日：2000-03-07
申请号：US69944
申请日：1998-04-30
申请人： Yuehu Pu
发明人： Yuehu Pu
IPC分类号： G21K1/093 , A61N5/10 , G21K5/02 , G21K5/04 , G21K5/10 , A61N5/00
CPC分类号： A61N5/1043 , G21K5/02 , G21K5/10 , A61N2005/1087 , A61N2005/1095
摘要： A charged particle beam irradiation apparatus includes two electromagnets arranged in series along a direction of an incident axis of a charged particle beam, for deflecting the charged particle beam in opposite directions, an energy modulator including a cylindrical member having a length and a distribution of wall thickness in a circumferential direction, a first rotational drive for rotating the cylindrical member around a rotation axis, and a detector for detecting the angular position of the cylindrical member. The energy modulator is disposed at a downstream side of the scanning electromagnets so that the deflected charged particle beam passes through the rotation axis. The apparatus includes an energy degrader for limiting energy of the charged particle beam, and a second rotational drive for rotating the scanning electromagnets and the energy modulator together around the incident axis of the charged particle beam.
摘要翻译：带电粒子束照射装置包括沿着带电粒子束的入射轴的方向串联布置的两个电磁体，用于使带电粒子束沿相反方向偏转，能量调制器包括具有长度和壁分布的圆柱形构件在圆周方向上的厚度，用于使圆筒形构件围绕旋转轴线旋转的第一旋转驱动器和用于检测圆柱形构件的角位置的检测器。能量调制器设置在扫描电磁体的下游侧，使得偏转的带电粒子束通过旋转轴。该装置包括用于限制带电粒子束的能量的能量降解器，以及用于围绕带电粒子束的入射轴旋转扫描电磁体和能量调制器的第二旋转驱动器。

8. 发明授权

US08658991B2 Particle beam irradiation apparatus utilized in medical field 有权
标题翻译：用于医疗领域的粒子束照射装置
公开(公告)号：US08658991B2
公开(公告)日：2014-02-25
申请号：US13003688
申请日：2009-06-03
申请人： Yuehu Pu , Katsuhisa Yoshida , Yuichi Yamamoto , Hidenobu Sakamoto , Taizo Honda , Hisashi Harada , Takaaki Iwata
发明人： Yuehu Pu , Katsuhisa Yoshida , Yuichi Yamamoto , Hidenobu Sakamoto , Taizo Honda , Hisashi Harada , Takaaki Iwata
IPC分类号： A61N5/00
CPC分类号： A61N5/10 , A61N5/1043 , A61N2005/1087
摘要： In order to obtain a particle beam irradiation apparatus that enlarges the dose distribution of beam spots while suppressing a decrease of the maximum available range of a charged particle beam, the particle beam irradiation apparatus includes a particle beam acceleration means; particle beam transport means; scanning apparatus that includes first scanning means and second scanning means, and two-dimensionally scans the beam; and irradiation control means that controls the scanning apparatus so as to irradiate the beam onto a target region including a plurality of small regions. The irradiation control means controls the first scanning means so as to scan the beam over a small region serving as an irradiation subject among the plurality of the small regions, and controls the second scanning means so as to change the small region serving as the irradiation subject to be a different small region among the plurality of the small regions.
摘要翻译：为了获得粒子束照射装置，其粒子束照射装置包括粒子束加速装置，粒子束照射装置在抑制带电粒子束的最大可用范围的减小的同时，扩大束斑的剂量分布，粒子束传送装置; 扫描装置，其包括第一扫描装置和第二扫描装置，并二维地扫描光束; 以及照射控制装置，其控制扫描装置以将束照射到包括多个小区域的目标区域上。照射控制装置控制第一扫描装置，以便在多个小区域中的用作照射对象的小区域上扫描光束，并且控制第二扫描装置以改变用作照射对象的小区域成为多个小区域中的不同小区域。

9. 发明授权

US08525448B2 Circular accelerator and operating method therefor 有权
标题翻译：圆形加速器及其操作方法
公开(公告)号：US08525448B2
公开(公告)日：2013-09-03
申请号：US13368435
申请日：2012-02-08
申请人： Hirofumi Tanaka , Kazuo Yamamoto , Nobuyuki Haruna , Yuehu Pu , Kanji Shinkawa , Takayuki Kashima
发明人： Hirofumi Tanaka , Kazuo Yamamoto , Nobuyuki Haruna , Yuehu Pu , Kanji Shinkawa , Takayuki Kashima
IPC分类号： H05H13/00
CPC分类号： H05H13/005 , H05H7/12 , H05H13/02
摘要： The circular accelerator comprises: a bending electromagnet that generates a bending magnetic field; a radio-frequency power source that generates a radio-frequency electric field in accordance with an orbital frequency of charged particles; a radio-frequency electromagnetic field coupling part connected to the radio-frequency power source; an acceleration electrode connected to the radio-frequency electromagnetic field coupling part; and an acceleration-electrode-opposing ground plate provided to form an acceleration gap between the plate itself and the acceleration electrode, for generating the radio-frequency electromagnetic field in an orbiting direction of the charged particles; wherein the bending electromagnet generates the bending magnetic field varying in such a way that the orbital frequency of the charged particles varies in a variation range of 0.7% to 24.7% with respect to an orbital frequency at the charged-particles' extraction portion, during a time of injection to extraction of the particles.
摘要翻译：圆形加速器包括：产生弯曲磁场的弯曲电磁体; 射频电源，其根据带电粒子的轨道频率产生射频电场; 连接到所述射频电源的射频电磁场耦合部; 连接到射频电磁场耦合部分的加速电极; 以及加速电极对置的接地板，其设置成在板本身和加速电极之间形成加速间隙，用于在带电粒子的运动方向上产生射频电磁场; 其中所述弯曲电磁体产生所述弯曲磁场，所述弯曲磁场以使得所述带电粒子的轨道频率相对于所述带电粒子提取部分的轨道频率在0.7％至24.7％的变化范围内变化的方式变化，注射时间来提取颗粒。

10. 发明申请

US20130053617A1 PARTICLE BEAM IRRADIATION APPARATUS AND PARTICLE BEAM THERAPY SYSTEM 有权
标题翻译：颗粒光束辐射装置和颗粒束治疗系统
公开(公告)号：US20130053617A1
公开(公告)日：2013-02-28
申请号：US13696736
申请日：2011-06-22
申请人： Yuehu Pu , Hisashi Harada , Taizo Honda
发明人： Yuehu Pu , Hisashi Harada , Taizo Honda
IPC分类号： A61N5/10
CPC分类号： G21K1/046 , A61N5/1043 , A61N5/1045 , A61N5/1048 , A61N2005/1052 , A61N2005/1054 , A61N2005/1087 , A61N2005/1095 , G21K1/10 , G21K5/00
摘要： A particle beam irradiation apparatus comprises a particle beam shielding member which shields a part of a particle beam which is scanned, a prompt signal detector which detects a prompt signal which is generated when the particle beam which is scanned collides with the particle beam shielding member and a signal comparison device which predicts and obtains a generation pattern of a prompt signal which is generated with a predetermined scanning pattern and stores as a signal time pattern for comparison, wherein the signal comparison device detects an abnormality of scanning of a particle beam or the particle beam shielding member by comparing a detected signal time pattern which is a time pattern of a signal which is detected by the prompt signal detector to a signal time pattern for comparison which is stored.
摘要翻译：粒子束照射装置包括：屏蔽被扫描的粒子束的一部分的粒子束屏蔽构件;检测当被扫描的粒子束与粒子束屏蔽构件相撞时产生的提示信号的迅速信号检测器;以及信号比较装置，其预测并获得以预定扫描图案生成的提示信号的生成模式，并存储为用于比较的信号时间图案，其中信号比较装置检测粒子束或粒子的扫描异常通过将作为由快速信号检测器检测的信号的时间图案的检测信号时间图案与存储的用于比较的信号时间模式进行比较来检测光束屏蔽部件。

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