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1. 发明授权

US06176832B1 Cardiovascular information measurement system 有权
标题翻译：心血管信息测量系统
公开(公告)号：US06176832B1
公开(公告)日：2001-01-23
申请号：US09141263
申请日：1998-08-27
申请人： Yoshiyuki Habu , Mitsutoshi Yaegashi
发明人： Yoshiyuki Habu , Mitsutoshi Yaegashi
IPC分类号： A61B502
CPC分类号： A61B5/0285 , A61B8/06
摘要： It is an object of the present invention to provide a cardiovascular information measurement system capable of performing an accurate blood pressure measurement and calculating an accurate cardiovascular index in consideration of the pulsation of a blood vessel wall. To achieve this object, the cardiovascular information measurement system includes ultrasonic transducer groups (4a, 4b) for simultaneously detecting sectional shapes (3a, 3b) of two arterial portions, a cross-sectional area calculation unit (5) for calculating cross-sectional areas of the two arterial portions on the basis of the detected sectional shapes, a flow velocity calculation unit (6) for calculating an average blood flow velocity in an artery on the basis of the cross-sectional areas calculated by the cross-sectional area calculation unit (5), a pulse wave velocity calculation unit (7) for calculating a pulse wave propagation velocity between the two arterial portions in accordance with time changes in the detected sectional shapes of the two arterial portions, a relative blood pressure calculation unit (8) for calculating a relative blood pressure value to a reference blood pressure value obtained in a specific time phase, on the basis of the calculated blood flow velocity and the calculated pulse wave propagation velocity, and an absolute blood pressure calculation unit (10) for calculating an absolute blood pressure value on the basis of the relative blood pressure value and the reference blood pressure value obtained in the specific time phase and measured in advance.
摘要翻译：本发明的目的是提供一种心血管信息测量系统，其能够进行精确的血压测量并考虑到血管壁的脉动来计算准确的心血管指数。为了实现该目的，心血管信息测量系统包括用于同时检测两个动脉部分的截面形状（3a，3b）的超声波换能器组（4a，4b），用于计算横截面积的横截面积计算单元（5）基于检测到的截面形状的两个动脉部分的流量计算单元（6），用于基于由横截面积计算单元计算出的横截面积来计算动脉中的平均血流速度（5），根据检测到的两个动脉部分的截面形状的时间变化计算两个动脉部分之间的脉搏波传播速度的脉搏波速度计算部（7），相对血压计算部（8）用于基于所计算的血流速度a计算在特定时间段中获得的参考血压值的相对血压值计算出的脉搏波传播速度和绝对血压计算单元（10），用于基于在特定时间段中获得的相对血压值和参考血压值来计算绝对血压值，并且预先测量。

2. 发明申请

US20130281914A1 TRANSDERMAL DRUG ADMINISTRATION DEVICE 审中-公开
标题翻译：转管药物管理装置
公开(公告)号：US20130281914A1
公开(公告)日：2013-10-24
申请号：US13996384
申请日：2011-12-19
申请人： Mitsutoshi Yaegashi
发明人： Mitsutoshi Yaegashi
IPC分类号： A61N1/30
CPC分类号： A61N1/303 , A61N1/044 , A61N1/325
摘要： A transdermal drug administration device which comprises a patch that is provided with: a donor gel in which a medical agent is sealed; a reference gel; a first electrode that is connected to the donor gel; and a second electrode that is connected to the reference gel. When the patch is applied to the skin, a direct current is applied between the first electrode and the second electrode at a predetermined cycle and an alternating current is applied between the first electrode and the second electrode during the periods when a direct current is not applied, thereby obtaining the capacitance. The application state of the patch is determined based on the thus-obtained capacitance.
摘要翻译：一种透皮给药装置，其特征在于，具有补片，所述补片具有：药剂被密封的供体凝胶; 参考凝胶; 与供体凝胶连接的第一电极; 以及连接到参考凝胶的第二电极。当贴片施加于皮肤时，以预定的周期在第一电极和第二电极之间施加直流电流，并且在不施加直流电的时段期间在第一电极和第二电极之间施加交流电流，从而获得电容。基于由此获得的电容确定贴片的应用状态。

3. 发明授权

US08226542B2 Cardiac assist system with cell transplantation aspects 有权
标题翻译：心脏辅助系统与细胞移植方面
公开(公告)号：US08226542B2
公开(公告)日：2012-07-24
申请号：US12237823
申请日：2008-09-25
申请人： Mitsutoshi Yaegashi
发明人： Mitsutoshi Yaegashi
IPC分类号： A61N1/362
CPC分类号： A61M1/10 , A61B34/73 , A61F2002/30079 , A61F2002/30668 , A61F2002/30677 , A61F2210/009 , A61F2250/0001 , A61M1/1006 , A61M1/1008 , A61M1/1055 , A61M1/1068 , A61M1/12 , A61M1/122 , A61M1/127
摘要： A ventricular assist system includes a controller supplying a DC voltage or an AC voltage, and electromagnets adapted to be adhered to an infarct portion of a heart at the time of embedding a pump. After embedding the system, cells enclosed in capsules are released into the surroundings of the infarct portion by use of a catheter. The capsules are magnetic so that they can be concentrated onto the infarct portion by magnetic fields of the electromagnets, and are broken in the vicinity of the infarct portion, whereby cells effective for regeneration of cardiac muscles can be conveyed to the infarct portion in a noninvasive manner after the embedding of the ventricular assist system.
摘要翻译：心室辅助系统包括提供DC电压或AC电压的控制器，以及适于在嵌入泵时粘附到心脏的梗塞部分的电磁体。在嵌入系统之后，封装在胶囊中的细胞通过使用导管释放到梗塞部分的周围。胶囊是磁性的，使得它们可以通过电磁体的磁场而集中在梗塞部分上，并且在梗死部分附近被破坏，从而有效地用于心肌再生的细胞可以被输送到非侵入性的梗塞部分方法是嵌入心室辅助系统。

4. 发明授权

US08226373B2 Sensorless magnetic bearing type blood pump apparatus 有权
标题翻译：无传感器磁轴承型血泵装置
公开(公告)号：US08226373B2
公开(公告)日：2012-07-24
申请号：US11946588
申请日：2007-11-28
申请人： Mitsutoshi Yaegashi
发明人： Mitsutoshi Yaegashi
IPC分类号： F04B49/06
CPC分类号： F04B49/06 , A61M1/1005 , A61M1/101 , A61M1/1012 , A61M1/1015 , A61M1/1017 , A61M1/1031 , A61M1/1036 , A61M1/1086 , F04D13/0666 , F04D29/047 , F04D29/048 , F16C32/0448 , F16C2316/18 , Y10S415/90
摘要： A sensorless magnetic bearing type blood pump apparatus includes a blood pump and a control mechanism. The blood pump has electromagnets for rotating a rotating body in a non-contact condition, and a hydrodynamic bearing section for rotating the rotating body in a non-contact condition when operation of the electromagnets is stopped. The apparatus is devoid of any sensors for determining the position of the rotating body. The control mechanism includes a pulse width modulation type electromagnet driving unit, a carrier component measuring unit for measuring carrier components of voltage and current in the driving unit, a modulation factor calculating unit which calculates a modulation factor using the carrier wave data, and a bearing mode changing-over mechanism for effecting change-over from the magnetic bearing mode to the hydrodynamic bearing mode when the calculated modulation factor is outside a predetermined range and for returning to the magnetic bearing mode after the change-over.
摘要翻译：无传感器的磁轴承型血液泵装置包括血液泵和控制机构。血泵具有用于在非接触状态下旋转旋转体的电磁体，以及用于在停止电磁铁操作时以非接触状态旋转旋转体的流体动力轴承部。该装置没有用于确定旋转体的位置的任何传感器。控制机构包括：脉宽调制型电磁体驱动部，用于测量驱动部的电压和电流的载体成分的载体成分测定部;调制度计算部，使用该载波数据计算调制度;以及轴承模式切换机构，当所计算的调制系数在预定范围之外时，用于从磁轴承模式转换到流体动力轴承模式，并且在转换之后返回到磁轴承模式。

5. 发明申请

US20120310143A1 IONTOPHORESIS PATCH 有权
标题翻译： IOPOPHORESIS PATCH
公开(公告)号：US20120310143A1
公开(公告)日：2012-12-06
申请号：US13578168
申请日：2011-02-09
申请人： Mitsutoshi Yaegashi , Akihiro Hasui , Hiroyuki Kubo
发明人： Mitsutoshi Yaegashi , Akihiro Hasui , Hiroyuki Kubo
IPC分类号： A61N1/30
CPC分类号： A61N1/0428
摘要： An iontophoresis patch is equipped with a donor gel and a reference gel which are disposed to contact an external conductor, for example, the skin of a patient and thereby output current from a current-carrying device to the external conductor. The iontophoresis patch includes: a donor portion having the donor gel containing a medical agent to be penetrated into the external conductor; a reference portion having a reference gel, mounted with the current-carrying device on the surface on the side opposite to the reference gel, and disposed on the external conductor apart from the donor portion; and an electrode film for supplying current from the current-carrying device to the donor gel and the reference gel.
摘要翻译：离子电渗贴片配备有供体凝胶和参考凝胶，其被设置为接触外部导体，例如患者的皮肤，从而将电流从载流装置输出到外部导体。离子电渗贴片包括：供体部分，其具有供体凝胶，其含有要渗入外导体的药剂; 具有参考凝胶的参考部分，其在与参考凝胶相反的一侧的表面上安装有载流装置，并且设置在远离供体部分的外部导体上; 以及用于从载流装置向供体凝胶和参考凝胶提供电流的电极膜。

6. 发明申请

US20100221130A1 BLOOD PUMP APPARATUS 有权
标题翻译：血液泵装置
公开(公告)号：US20100221130A1
公开(公告)日：2010-09-02
申请号：US12781254
申请日：2010-05-17
申请人： Mitsutoshi Yaegashi , Takehiko Asada , Takehisa Mori , Takayoshi Ozaki , Kenichi Suzuki
发明人： Mitsutoshi Yaegashi , Takehiko Asada , Takehisa Mori , Takayoshi Ozaki , Kenichi Suzuki
IPC分类号： F04B17/00 , F04D17/08
CPC分类号： F04D29/047 , A61M1/101 , A61M1/1012 , A61M1/1013 , A61M1/1015 , A61M1/1017 , A61M1/1031 , A61M1/1036 , A61M1/122 , F04D13/027 , F04D13/0666 , F04D15/0088
摘要： A blood pump apparatus comprises a housing, a centrifugal pump section including an impeller and rotating inside the housing to feed a fluid by a centrifugal force, an impeller rotational torque generation section for attracting thereto said impeller and rotating said impeller; and a plurality of grooves for hydrodynamic bearing provided on an inner surface of said housing at a side of said impeller rotational torque generation section, each of the grooves for hydrodynamic bearing having a first side and a second side both extending from a periphery of said portion in which a groove for hydrodynamic bearing is formed toward a central side thereof and opposed to each other, a third side connecting one end of said first side and one end of said second side to each other, and a fourth side connecting said other end of said first side and said other end of said second side to each other; said first side and said second side are formed as a circular arc respectively in such a way that centers of said circular arcs are different from each other.
摘要翻译：一种血泵装置，包括壳体，包括叶轮的离心泵部分，并且在所述壳体内旋转以通过离心力供给流体;叶轮旋转扭矩产生部，用于吸引所述叶轮并旋转所述叶轮; 以及多个用于流体动力轴承的槽，设置在所述壳体的位于所述叶轮旋转转矩产生部分侧的内表面上，每个用于流体动力轴承的槽具有第一侧和第二侧，两个槽从所述部分的周边延伸其中用于流体动力轴承的槽形成为朝向其中心侧并且彼此相对的第三侧，第三侧将所述第一侧的一端和所述第二侧的一端彼此连接，第四侧将所述第二侧的另一端所述第一侧和所述第二侧的另一端彼此相对; 所述第一侧和所述第二侧分别形成为圆弧，使得所述圆弧的中心彼此不同。

7. 发明授权

US06315722B1 Ultrasonic diagnostic device 有权
标题翻译：超声波诊断装置
公开(公告)号：US06315722B1
公开(公告)日：2001-11-13
申请号：US09538237
申请日：2000-03-30
申请人： Mitsutoshi Yaegashi
发明人： Mitsutoshi Yaegashi
IPC分类号： A61B800
CPC分类号： G01S7/52034 , G01S7/52053
摘要： An ultrasonic diagnostic device comprising an ADC 60 that converts signals to digital format, a time axis extension unit 70 that is capable of writing and reading the digital data, a data compression unit 80 that compresses the read data, a memory unit 90 that stores the compressed data, a data expanding unit that expands the compressed data stored in the memory unit, and a DAC 110 that converts the expanded data from a digital format to an analog format, wherein optimum images can be displayed for diagnosis by means of filtering, logarithmically converting, and detecting before inputting the data into the digital scan converter 210.
摘要翻译：一种超声波诊断装置，包括将信号转换为数字格式的ADC 60，能够写入和读取数字数据的时间轴扩展单元70，压缩读取的数据的数据压缩单元80，存储读取数据的存储单元90 压缩数据，扩展存储在存储器单元中的压缩数据的数据扩展单元，以及将扩展数据从数字格式转换为模拟格式的DAC 110，其中可以通过对数方式通过滤波来显示最佳图像进行诊断在将数据输入数字扫描转换器210之前进行转换和检测。

8. 发明授权

US6106462A Ultrasonic diagnostic apparatus 失效
标题翻译：超声波诊断仪
公开(公告)号：US6106462A
公开(公告)日：2000-08-22
申请号：US919322
申请日：1997-08-28
申请人： Mitsutoshi Yaegashi , Kazuhiro Hirota
发明人： Mitsutoshi Yaegashi , Kazuhiro Hirota
IPC分类号： A61B8/00 , A61B8/12 , G01S7/52 , G01S15/89 , H03H7/01
CPC分类号： H03H7/0115 , G01S7/52046 , G01S15/894 , G01S7/52026
摘要： Disclosed is a celiac diagnostic apparatus in which the characteristics of a filter for filtering a wave reflected by a tissue inside an object are made steep, and an ultrasonic wave capable of making a high-accuracy diagnosis for the object is used. C1, C2, and C3 are constituted using variable capacitance diodes. Three LC filters, i.e., an LC filter constituted by L1 and C1, an LC filter constituted by L2 and C2, and an LC filter constituted by L3 and C3 are serially connected to constitute the filter, whose cutoff characteristics is still practical even when the cutoff frequency exceeds 20 MHz.
摘要翻译：公开了一种腹腔诊断装置，其中用于过滤由物体内的组织反射的波的滤波器的特性变得陡峭，并且使用能够对该物体进行高精度诊断的超声波。 C1，C2和C3使用可变电容二极管构成。三个LC滤波器，即由L1和C1构成的LC滤波器，由L2和C2构成的LC滤波器和由L3和C3构成的LC滤波器串联连接以构成滤波器，其截止特性即使在截止频率超过20MHz。

9. 发明授权

US09517331B2 Iontophoresis patch 有权
标题翻译：离子电渗贴片
公开(公告)号：US09517331B2
公开(公告)日：2016-12-13
申请号：US13578168
申请日：2011-02-09
申请人： Mitsutoshi Yaegashi , Akihiro Hasui , Hiroyuki Kubo
发明人： Mitsutoshi Yaegashi , Akihiro Hasui , Hiroyuki Kubo
IPC分类号： A61N1/30 , A61N1/04
CPC分类号： A61N1/0428
摘要： An iontophoresis patch is equipped with a donor gel and a reference gel which are disposed to contact an external conductor, for example, the skin of a patient and thereby output current from a current-carrying device to the external conductor. The iontophoresis patch includes: a donor portion having the donor gel containing a medical agent to be penetrated into the external conductor; a reference portion having a reference gel, mounted with the current-carrying device on the surface on the side opposite to the reference gel, and disposed on the external conductor apart from the donor portion; and an electrode film for supplying current from the current-carrying device to the donor gel and the reference gel.
摘要翻译：离子电渗贴片配备有供体凝胶和参考凝胶，其被设置为接触外部导体，例如患者的皮肤，从而将电流从载流装置输出到外部导体。离子电渗贴片包括：供体部分，其具有供体凝胶，其含有要渗入外导体的药剂; 具有参考凝胶的参考部分，其在与参考凝胶相反的一侧的表面上安装有载流装置，并且设置在远离供体部分的外部导体上; 以及用于从载流装置向供体凝胶和参考凝胶提供电流的电极膜。

10. 发明授权

US07748964B2 Blood pump apparatus 有权
标题翻译：血泵装置
公开(公告)号：US07748964B2
公开(公告)日：2010-07-06
申请号：US11087851
申请日：2005-03-24
申请人： Mitsutoshi Yaegashi , Takehiko Asada , Takehisa Mori , Takayoshi Ozaki , Kenichi Suzuki
发明人： Mitsutoshi Yaegashi , Takehiko Asada , Takehisa Mori , Takayoshi Ozaki , Kenichi Suzuki
IPC分类号： F04B17/03 , F16C32/06
CPC分类号： F04D29/047 , A61M1/101 , A61M1/1012 , A61M1/1013 , A61M1/1015 , A61M1/1017 , A61M1/1031 , A61M1/1036 , A61M1/122 , F04D13/027 , F04D13/0666 , F04D15/0088
摘要： A blood pump apparatus comprises a housing, a centrifugal pump section including an impeller and rotating inside the housing to feed a fluid by a centrifugal force, an impeller rotational torque generation section for attracting thereto said impeller and rotating said impeller; and a plurality of grooves for hydrodynamic bearing provided on an inner surface of said housing at a side of said impeller rotational torque generation section, each of the grooves for hydrodynamic bearing having a first side and a second side both extending from a periphery of said portion in which a groove for hydrodynamic bearing is formed toward a central side thereof and opposed to each other, a third side connecting one end of said first side and one end of said second side to each other, and a fourth side connecting said other end of said first side and said other end of said second side to each other; said first side and said second side are formed as a circular arc respectively in such a way that centers of said circular arcs are different from each other.
摘要翻译：一种血泵装置，包括壳体，包括叶轮的离心泵部分，并且在所述壳体内旋转以通过离心力供给流体;叶轮旋转扭矩产生部，用于吸引所述叶轮并旋转所述叶轮; 以及多个用于流体动力轴承的槽，设置在所述壳体的位于所述叶轮旋转转矩产生部分侧的内表面上，每个用于流体动力轴承的槽具有第一侧和第二侧，两个槽从所述部分的周边延伸其中用于流体动力轴承的槽形成为朝向其中心侧并且彼此相对的第三侧，第三侧将所述第一侧的一端和所述第二侧的一端彼此连接，第四侧将所述第二侧的另一端所述第一侧和所述第二侧的另一端彼此相对; 所述第一侧和所述第二侧分别形成为圆弧，使得所述圆弧的中心彼此不同。

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