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1. 发明授权

US07351422B2 Hemostatic soluble cellulose fibers containing coagulating protein for treating wound and process for producing the same 失效
标题翻译：含有用于治疗伤口的凝血蛋白的止血可溶性纤维素纤维及其制备方法
公开(公告)号：US07351422B2
公开(公告)日：2008-04-01
申请号：US10069561
申请日：2001-02-22
申请人： Yoshio Jo , Motonori Aoshima , Koji Tanabe , Koichi Matsushita , Toshiki Inoue
发明人： Yoshio Jo , Motonori Aoshima , Koji Tanabe , Koichi Matsushita , Toshiki Inoue
IPC分类号： A61F2/00 , A61K9/00 , A61K9/70 , A61K35/12 , C08B11/00
CPC分类号： D06M23/06 , A61K31/717 , A61L15/225 , A61L15/28 , A61L15/32 , A61L2400/04 , D06M11/38 , D06M13/21 , D06M15/15 , C08L1/26 , C08L89/00 , C08L1/00
摘要： Proposed is a novel soluble trauma-healing and hemostatic cellulose fiber capable of absorbing and readily dissolving hemorrhaging trauma loci when applied thereto and of promoting the hemostatic action of blood platelets and fibrin and cell adhesion to the trauma site. The coagulation protein-containing soluble trauma-healing and hemostatic cellulose fiber is produced in that after treatment of a natural or regenerated cellulose fiber with an aqueous sodium hydroxide solution, said fiber is carboxymethylated by reaction with a monochloro acetic acid solution for a given time (hours) in such a manner that the degree of partial substitution of the glucose units constituting the cellulose molecule (etherification degree) is 0.5-less than 1.0% and that, furthermore, the coagulation proteins fibrinogen, thrombin, and coagulation factor XIII are imparted by surface application or chemical bonding.
摘要翻译：提出了一种新颖的可溶性创伤愈合和止血纤维素纤维，其能够吸收并容易地溶解出血创伤基因座，并且促进血小板和纤维蛋白的止血作用以及细胞粘附于创伤部位。产生含凝固蛋白质的可溶性创伤愈合和止血纤维素纤维，其中在用氢氧化钠水溶液处理天然或再生纤维素纤维后，所述纤维通过与一氯乙酸溶液反应给定时间而羧甲基化（给定时间小时），构成纤维素分子的葡萄糖单元的部分取代度（醚化度）为0.5％以下，并且凝固蛋白质纤维蛋白原，凝血酶和凝血因子XIII由表面应用或化学键合。

2. 发明授权

US07294750B2 Absorbable protective coatings for wound with the use of cellulose sponge and process for producing the same 失效
标题翻译：使用纤维素海绵的伤口的可吸收保护涂层及其制造方法
公开(公告)号：US07294750B2
公开(公告)日：2007-11-13
申请号：US10221405
申请日：2001-09-04
申请人： Kumiko Taniguchi , Isao Kohno , Koji Tanabe , Yoshio Jo , Isao Ohnishi , Keisuke Kosake , Yuri Koyama
发明人： Kumiko Taniguchi , Isao Kohno , Koji Tanabe , Yoshio Jo , Isao Ohnishi , Keisuke Kosake , Yuri Koyama
IPC分类号： A61F13/00
CPC分类号： A61L15/18 , A61B17/00491 , A61B17/0057 , A61L15/28 , A61L15/425 , C08L1/24 , C08L1/02
摘要： An absorptive wound covering protecting material and a method for preparing an absorptive wound covering protecting material are characterized by solidifying a sponge raw solution containing no reinforcement that is obtained by mixing viscose and crystalline mirabilite as main raw materials, or a sponge raw solution obtained by mixing viscose containing a reinforcement comprising natural fibers having a length of at least 5 mm to 40 mm, and crystalline mirabilite as main raw materials, by performing a heat treatment on the sponge raw solution, and then forming the solidified cellulose sponge in a thickness somewhat greater than a desired thickness, and then forming the cellulose sponge in a sheet form having a desired thickness by compressing the cellulose sponge, and, if required, carboxymethylating hydroxyl groups in a glucose unit constituting a cellulose sponge so that a degree of substitution of the hydroxyl groups is from 0.5 to less than 1.0, and then, forming an incision the cellulose sponge.
摘要翻译：吸水性覆盖保护材料的吸收性伤口和吸收性伤口覆盖保护材料的制备方法的特征在于，将粘胶和结晶芒硝作为主要原料混合而得到的不含增强物的海绵原料溶液固化，或通过混合得到的海绵原液含有长度为至少5mm〜40mm的天然纤维的增粘剂和结晶芒硝作为主要原料，通过对海绵原液进行热处理，然后形成厚度稍大的固化纤维素海绵然后通过压缩纤维素海绵，并且如果需要，在构成纤维素海绵的葡萄糖单元中羧甲基化羟基，使得羟基的取代程度高于期望的厚度，然后通过压缩纤维素海绵形成具有所需厚度的片状的纤维素海绵组为0.5〜小于1.0，然后形成切口纤维素海绵。

3. 发明授权

US12036245B2 Pharmaceutical composition and cosmetic composition 有权
公开(公告)号：US12036245B2
公开(公告)日：2024-07-16
申请号：US17292298
申请日：2019-10-04
申请人： Koji Tanabe , I Peace, Inc.
发明人： Koji Tanabe , Kenta Suto
IPC分类号： A61K35/545 , A61K8/98 , A61P17/14 , A61Q19/08
CPC分类号： A61K35/545 , A61K8/982 , A61P17/14 , A61Q19/08
摘要： Provided are a pharmaceutical composition or a pharmaceutical composition raw material, which contains supernatant from a culture medium used during culture to induce pluripotent stem cells.

4. 发明授权

US11518974B2 Pluripotent stem cell production system 有权
公开(公告)号：US11518974B2
公开(公告)日：2022-12-06
申请号：US15756031
申请日：2016-08-31
申请人： I PEACE, INC. , Koji Tanabe
发明人： Koji Tanabe , Brendan Kelly , Kenta Suto , Hidenori Shimoda , Ryoji Hiraide
IPC分类号： C12N5/074 , C12M1/36 , C12M1/00 , C12M1/34 , C12M1/33 , C12M1/42 , C12N5/078 , C12M3/00 , C12M1/02 , C12M1/12
摘要： A stem cell production system provided with a preintroduction cell-feeding solution channel 20 through which a solution containing cells passes, an induction factor-feeding solution mechanism 21 for feeding a pluripotency induction factor to the preintroduction cell-feeding solution channel 20, a factor introduction device 30 connected to the preintroduction cell-feeding solution channel 20 for making cells with induction factor introduced by introducing the pluripotency induction factor into the cells, a cell mass-making device 40 for making multiple cell masses comprising stem cells by culturing the cells with induction factor introduced, and a packaging device 100 for sequentially packaging each of the multiple cell masses.

5. 发明授权

US08993329B2 Method of efficiently establishing induced pluripotent stem cells 有权
标题翻译：有效建立诱导性多能干细胞的方法
公开(公告)号：US08993329B2
公开(公告)日：2015-03-31
申请号：US13393158
申请日：2010-09-22
申请人： Shinya Yamanaka , Koji Tanabe
发明人： Shinya Yamanaka , Koji Tanabe
IPC分类号： C12N15/00 , C12N5/00 , C12N5/074
CPC分类号： C12N5/0696 , C12N2501/602 , C12N2501/603 , C12N2501/604 , C12N2501/608 , C12N2510/00
摘要： Provided are a method of improving iPS cell establishment efficiency, comprising the step of transferring Lin28B or a nucleic acid that encodes Lin28B to a somatic cell, particularly to a somatic cell on which Lin28 is ineffective or less effective than Lin28B in improving iPS cell establishment efficiency, and a method of producing an iPS cell, comprising the step of transferring Lin28B or a nucleic acid that encodes Lin28B and a nuclear reprogramming substance to a somatic cell. Also provided are an iPS cell comprising a nucleic acid that encodes Lin28B, that can be obtained by the method of producing an iPS cell, and a method of somatic cell production by forcing the iPS cell to differentiate into a somatic cell.
摘要翻译：提供一种提高iPS细胞建立效率的方法，其包括将Lin28B或编码Lin28B的核酸转移到体细胞，特别是Lin28在改善iPS细胞建立效率方面无效或低于Lin28B的体细胞的步骤以及生产iPS细胞的方法，包括将Lin28B或编码Lin28B和核重编程物质的核酸转移到体细胞的步骤。还提供了包含编码Lin28B的核酸的iPS细胞，其可以通过制备iPS细胞的方法获得，以及通过强迫iPS细胞分化成体细胞的体细胞产生的方法。

6. 发明授权

US08508492B2 Touch panel and method of detecting press operation position thereon 失效
标题翻译：触摸面板及其上检测按压操作位置的方法
公开(公告)号：US08508492B2
公开(公告)日：2013-08-13
申请号：US12768203
申请日：2010-04-27
申请人： Koji Tanabe , Hirotoshi Watanabe , Hidetoshi Hiraoka , Kenichi Matsumoto
发明人： Koji Tanabe , Hirotoshi Watanabe , Hidetoshi Hiraoka , Kenichi Matsumoto
IPC分类号： G06F3/041
CPC分类号： G06F3/045
摘要： In a touch panel, one of conductive layers on a bottom of an upper substrate and on a top of a lower substrate is formed of belt-shaped conductive layers. The other is a single conductive layer facing the belt-shaped conductive layers. The single conductive layer is provided with a pair of electrodes in positions corresponding to both ends in a direction where the belt-shaped conductive layers extend. When the upper substrate is pressed while a voltage is applied between the pair of electrodes, the top and lower conductive layers contact with each other. Then, a voltage value corresponding to the pressed position in the direction where the belt-shaped conductive layers extend is generated from any of the belt-shaped conductive layers. From the voltage value and the position of the belt-shaped conductive layer from which the voltage value is generated, a pressed position on the upper substrate can be detected.
摘要翻译：在触摸面板中，上基板的底部和下基板的顶部上的导电层中的一个由带状导电层形成。另一个是面向带状导电层的单个导电层。单个导电层在带状导电层延伸的方向上的两端的位置处设置有一对电极。当在一对电极之间施加电压的同时按压上基板时，上导电层和下导电层彼此接触。然后，从任何带状导电层产生与带状导电层延伸的方向上的按压位置对应的电压值。根据产生电压值的带状导电层的电压值和位置，可以检测上基板上的按压位置。

7. 发明申请

US20110193815A1 TOUCH PANEL 审中-公开
标题翻译：触控面板
公开(公告)号：US20110193815A1
公开(公告)日：2011-08-11
申请号：US12935944
申请日：2009-02-19
申请人： Koji Tanabe , Shoji Fujii , Hideo Iguchi
发明人： Koji Tanabe , Shoji Fujii , Hideo Iguchi
IPC分类号： G06F3/045
CPC分类号： G06F3/045
摘要： A touch panel includes a light-transmittable upper board, a light-transmittable upper resistive layer provided on a lower surface of the upper board, a light-transmittable lower resistive layer having an upper surface facing a lower surface of the upper resistive layer with a predetermined gap, a light-transmittable lower board provided on a lower surface of the lower resistive layer, plural conductive particles provided on at least one of the lower surface of the upper resistive layer and the upper surface of the lower resistive layer, and a transparent resin portion for fixing the conductive particles to the at least one of the lower surface of the upper resistive layer and the upper surface of the lower resistive layer. Upon having a display element provided on a lower surface of the lower board, this touch panel allows the display element to be easily visually recognized, and is inexpensive and operated easily.
摘要翻译：触摸面板包括可透光上板，设置在上板的下表面上的可透光上电阻层，可透光下电阻层，其具有面向上电阻层的下表面的上表面，具有设置在下电阻层的下表面上的可透光下板，设置在上电阻层的下表面和下电阻层的上表面中的至少一个上的多个导电颗粒，以及透明树脂部分，用于将导电颗粒固定到上电阻层的下表面和下电阻层的上表面中的至少一个。当具有设置在下板的下表面上的显示元件时，该触摸面板允许显示元件容易地被视觉识别，并且便宜并且操作容易。

8. 发明授权

US07595790B2 Pressure sensitive conductive sheet, method of manufacturing the same, and touch panel using the same 失效
标题翻译：压敏导电片，其制造方法和使用其的触摸面板
公开(公告)号：US07595790B2
公开(公告)日：2009-09-29
申请号：US11313197
申请日：2005-12-20
申请人： Yasutaka Yamamoto , Koji Tanabe
发明人： Yasutaka Yamamoto , Koji Tanabe
IPC分类号： G09G5/00
CPC分类号： G06F3/0414 , G06F3/045 , Y10T428/25
摘要： A pressure sensitive conductive sheet is provided by having a plurality of ferromagnetic conductive particles dispersed in a transparent elastic member joined together and linearly aligned with the thickness direction thereby forming a linear aggregate and then having the linear aggregate segmented into a plurality conductive elements, held linearly aligned with the thickness direction, with predetermined gaps formed therebetween. Further, a touch panel having good transparency and allowing stabilized operation is provided by interposing the pressure sensitive conductive sheet between an upper conductive layer on the lower face of an upper substrate and a lower conductive layer on the upper face of a lower substrate.
摘要翻译：通过具有分散在连接在一起并与厚度方向线性对准的透明弹性部件中的多个铁磁性导电粒子形成压敏导电片，从而形成直线聚集体，然后将线状聚集体分割成多个导电元件，线性地保持与厚度方向对准，其间形成有预定的间隙。此外，通过在上基板的下表面上的上导电层和下基板的上表面的下导电层之间插入压敏导电片，提供了具有良好的透明度并且允许稳定的操作的触摸面板。

9. 发明申请

US20090095612A1 MOVABLE CONTACT ASSEMBLY AND SWITCH USING THE SAME 失效
标题翻译：使用相同的触点组合和开关
公开(公告)号：US20090095612A1
公开(公告)日：2009-04-16
申请号：US12246417
申请日：2008-10-06
申请人： Koji Tanabe , Yousuke Chikahisa , Tsutomu Aisaka
发明人： Koji Tanabe , Yousuke Chikahisa , Tsutomu Aisaka
IPC分类号： H01H13/14
CPC分类号： H01H13/83 , H01H2205/016 , H01H2209/002 , H01H2209/082 , H01H2219/044 , H01H2219/056 , H01H2219/06 , H01H2219/062 , H01H2221/07
摘要： A movable contact assembly includes a light guiding sheet which is light transmittable, and a movable contact provided on the light guiding sheet. The light guiding sheet has a portion having the movable contact provided thereon and a portion having plural grooves provided therein. The grooves constitute a light inlet for introducing light into the light guiding sheet. This movable contact assembly can illuminate a switch preferably with a simple structure, providing the switch with an easily operation.
摘要翻译：可移动接触组件包括可透光的导光片和设置在导光片上的可动触头。导光片具有设置在其上的可动触头的部分和设置在其中的多个凹槽的部分。凹槽构成用于将光引入导光片的光入口。该可动触头组件可以以简单的结构照亮开关，为开关提供容易的操作。

10. 发明授权

US07406881B2 Touch panel and manufacturing method for the same 失效
标题翻译：触摸面板和制造方法相同
公开(公告)号：US07406881B2
公开(公告)日：2008-08-05
申请号：US11453505
申请日：2006-06-15
申请人： Koji Tanabe
发明人： Koji Tanabe
IPC分类号： G01D7/00
CPC分类号： G06F3/0414
摘要： A touch panel has an upper substrate, a lower substrate, an elastic layer, plural conducting wires, and a gel layer. An upper conductive layer is formed at a lower surface of the upper substrate, a lower conductive layer that faces the upper conductive layer with a gap in between is formed at a top surface of the lower substrate, and the elastic layer is formed at a top surface of the lower conductive layer. The conductive wires are partially buried in the elastic layer and are disposed in a manner vertically oriented with a gap from the upper conductive layer. The gel layer is formed between the upper conductive layer and the elastic layer. With this construction, the touch panel is obtainable that suffers less wrong operation and allows reliable operation.
摘要翻译：触摸面板具有上基板，下基板，弹性层，多根导线和凝胶层。在上基板的下表面形成上导电层，在下基板的上表面形成有与上导电层相对的上导电层的下导电层，并且在顶部形成弹性层下导电层的表面。导电线部分地埋在弹性层中，并且以与上导电层间隙垂直取向的方式设置。凝胶层形成在上导电层和弹性层之间。利用这种结构，可以获得触摸面板，其操作较少错误并且允许可靠的操作。

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