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1. 发明授权

US4731361A Alkeneamidocephalosporin esters 失效
标题翻译：烷基酰头孢菌素酯
公开(公告)号：US4731361A
公开(公告)日：1988-03-15
申请号：US845305
申请日：1986-03-27
申请人： Yoshio Hamashima , Koji Ishikura , Kyoji Minami , Tadatoshi Kubota , Tadashi Yoshida
发明人： Yoshio Hamashima , Koji Ishikura , Kyoji Minami , Tadatoshi Kubota , Tadashi Yoshida
IPC分类号： A01N43/86 , A61K20060101 , A61K31/345 , A61K31/397 , A61K31/427 , A61K31/54 , A61K31/545 , A61K31/546 , A61P31/04 , C07D20060101 , C07D277/30 , C07D501/04 , C07D501/18 , C07D501/20 , C07D501/22 , C07D501/24 , C07D501/34 , C07D501/36 , C07D501/46 , C07D501/59
CPC分类号： C07D501/20
摘要： An oral antibacterial, 7beta-[(Z)-2-(2-aminothiazol-4-yl)-2-alkenoylamino]-3-cephem-4-carboxylic acid pharmaceutically acceptable ester represented by the following formula: ##STR1## (wherein R is amino or protected amino,R.sup.1 is straight, branched, or cyclic alkyl optionally substituted by alkoxy,R.sup.2 is hydrogen or a 3-substitutent of cephalosporins,R.sup.3 is a pharmaceutically acceptable ester group, andX is sulfur or sulfinyl).
摘要翻译：口服抗菌剂，由下式表示的口服抗菌剂，7β-[（Z）-2-（2-氨基噻唑-4-基）-2-烯酰氨基] -3-头孢烯-4-羧酸的药学上可接受的酯 R为氨基或被保护的氨基，R1为任选被烷氧基取代的直链，支链或环状烷基，R2为氢或3-取代的头孢菌素，R3为药学上可接受的酯基，X为硫或亚磺酰基）。

2. 发明授权

US4578378A (Oxoheterocyclic carbonamido)cephem carboxylic acid derivatives 失效
标题翻译：（氧杂环碳酰氨基）头孢烯羧酸衍生物
公开(公告)号：US4578378A
公开(公告)日：1986-03-25
申请号：US625308
申请日：1984-06-27
申请人： Yoshio Hamashima , Koji Ishikura , Tadatoshi Kubota , Kyoji Minami
发明人： Yoshio Hamashima , Koji Ishikura , Tadatoshi Kubota , Kyoji Minami
IPC分类号： A61K31/397 , A61K31/535 , A61K31/5375 , A61K31/545 , A61K31/546 , A61P31/04 , C07D205/08 , C07D205/085 , C07D207/26 , C07D207/277 , C07D207/40 , C07D207/416 , C07D211/90 , C07D223/10 , C07D241/08 , C07D265/32 , C07D277/12 , C07D277/14 , C07D277/56 , C07D279/12 , C07D281/06 , C07D307/00 , C07D307/33 , C07D309/30 , C07D327/04 , C07D327/06 , C07D335/02 , C07D417/12 , C07D501/20 , C07D501/36 , C07D501/46 , C07D501/56 , C07D501/57 , C07D505/00 , C07D519/06 , C07D498/04
CPC分类号： C07D207/277 , C07D205/08 , C07D207/416 , C07D211/90 , C07D223/10 , C07D241/08 , C07D265/32 , C07D277/14 , C07D279/12 , C07D281/06 , C07D307/33 , C07D309/30 , C07D327/04 , C07D327/06 , C07D335/02 , C07D417/12 , C07D505/00 , Y02P20/55
摘要： Antibacterial 7.beta.-(oxo-saturated heterocyclic carbonamido)-3-cephem-4-carboxylic acid derivatives of the formula: ##STR1## (wherein R is hydrogen or methoxy; R.sup.1 is hydrogen or a nucleophilic group; R.sup.2 is hydrogen, light metal, or a carboxy protecting group; X is oxygen, sulfur, sulfinyl, or sulfonyl; Y is alkylene containing one or more hetero atoms; and Z is hydrogen or a substituent).
摘要翻译：具有下式的抗菌7β-（含氧饱和杂环碳酰氨基）-3-头孢烯-4-羧酸衍生物（其中R是氢或甲氧基; R 1是氢或亲核基团; R 2是氢，轻金属或羧基保护基; X是氧，硫，亚磺酰基或磺酰基; Y是含有一个或多个杂原子的亚烷基; Z是氢或取代基）。

3. 发明授权

US4731362A Alkylcarbamoyloxymethylcephem compounds 失效
标题翻译：烷基氨基甲酰氧基甲基头孢烯化合物
公开(公告)号：US4731362A
公开(公告)日：1988-03-15
申请号：US888435
申请日：1986-07-23
申请人： Yoshio Hamashima , Teruji Tsuji , Tetsuo Okada , Kyoji Minami , Hiroyuki Ishitobi , Koji Ishikura
发明人： Yoshio Hamashima , Teruji Tsuji , Tetsuo Okada , Kyoji Minami , Hiroyuki Ishitobi , Koji Ishikura
IPC分类号： A01N43/90 , A23K20/195 , A23L3/34 , A61K20060101 , A61K31/545 , A61K31/546 , A61P31/04 , C07D501/06 , C07D501/20 , C07D501/34 , C07D501/46
CPC分类号： C07D501/34 , Y02P20/55
摘要： An antibacterial 3-(alkylcarbamoyloxymethyl)-3-cephem-4-carboxylic acid or its derivatives represented by the following formula ##STR1## (wherein R is hydrogen or an amino-protecting group,R.sup.1 and R.sup.2 each is the same or different 1C to 8C alkyl,R.sup.3 is hydrogen, a salt or ester forming atom or group, andX is sulfur or sulfinyl),a pharmaceutical composition containing the same, a method for treating a bacterial infection with the same, and a method for preparing the same are disclosed.
摘要翻译：抗氧化剂3-（烷基氨基甲酰氧基甲基）-3-头孢烯-4-羧酸或其衍生物由下式表示：其中R为氢或氨基保护基，R1和R2各自为相同或不同的1C至 8C烷基，R3是氢，形成盐或酯的原子或基团，X是硫或亚磺酰基），含有它们的药物组合物，用于治疗细菌感染的方法及其制备方法披露

4. 发明授权

US5134138A Phenacylpyridiniothiocephalosporins 失效
标题翻译： PHENACYLPYRIDINIOTHIOCEPHALOSPORINS
公开(公告)号：US5134138A
公开(公告)日：1992-07-28
申请号：US550091
申请日：1990-07-09
申请人： Hiroshi Onoue , Kyoji Minami , Koji Ishikura
发明人： Hiroshi Onoue , Kyoji Minami , Koji Ishikura
IPC分类号： C07D501/18 , A61K31/00 , A61K31/545 , A61K31/546 , A61P31/00 , A61P31/04 , C07D501/00 , C07D501/04 , C07D501/36 , C07D501/57 , C07D505/00
CPC分类号： C07D505/00 , C07D501/00 , Y02P20/55
摘要： An antibacterial 3-vic-dihydroxyaroylmethylpyridiniothiomethyl cephalosporin (I) and its salts represented by the following formula: ##STR1## (wherein, R.sup.1 is amino group or acylamino; R.sup.2 is hydrogen or methoxy; R.sup.3 is hydrogen atom or substituent; R.sup.4 is vic-dihydroxyaryl; R.sup.5 is straight or branched lower alkylene; R.sup.6 is hydrogen, a carboxy-protecting group or combined with Y a negative charge; X is --O--, --S-- or sulfinyl; and Y is a counter-ion of pyridinio or combined with R.sup.6 a negative charge),a disinfecting and treating method of bacterial infection using it, and synthetic methods thereof are provided.

5. 发明授权

US3997528A Cephalosporin compounds 失效
标题翻译：头孢菌素化合物
公开(公告)号：US3997528A
公开(公告)日：1976-12-14
申请号：US517483
申请日：1974-10-22
申请人： Mitsuru Yoshioka , Masayuki Murakami , Yuji Sendo , Sadao Miyazaki , Koji Ishikura
发明人： Mitsuru Yoshioka , Masayuki Murakami , Yuji Sendo , Sadao Miyazaki , Koji Ishikura
IPC分类号： C07D501/18 , A61D7/00 , A61K31/43 , A61K31/545 , C07D501/04 , C07D501/06 , C07D501/16 , C07D501/20 , C07D501/24 , C07D501/38 , C07D501/40 , C07D501/42 , C07D501/44 , C07D501/46 , C07D501/60
CPC分类号： C07D501/38 , C07D501/24 , Y02P20/55
摘要： Antibacterial cephalosporin compounds of the following formula: ##STR1## wherein A and B each is a hydrogen, organic or inorganic acyl, or A and B combined together are a diacyl group derived from a polybasic acid; Y is a hydrogen or methoxy; R is a hydrogen or lower alkyl; R' is a hydrogen, alkali metal, organic base group or easily removable protecting group; m is 0 or 1; Z is an optionally substituted guanylhydrazono group, preparable from the corresponding oxo compound or its reactive derivative by reacting with a guanylhyrazine of the formula H.sub.2 Z or its reactive derivative, or by some other reactions.
摘要翻译：下式的抗菌头孢菌素化合物：其中A和B各自为氢，有机或无机酰基，或A和B组合在一起的是由多元酸衍生的二酰基; Y是氢或甲氧基; R是氢或低级烷基; R'是氢，碱金属，有机碱基或易脱除的保护基; m为0或1; Z是任选取代的脒基亚肼基，其可通过与式H2Z或其反应性衍生物的鸟苷酸反应或通过一些其它反应与相应的氧代化合物或其反应性衍生物制备。

6. 发明授权

US11416674B2 Information processing apparatus, method of processing information and storage medium 有权
公开(公告)号：US11416674B2
公开(公告)日：2022-08-16
申请号：US16514206
申请日：2019-07-17
申请人： Koji Ishikura , Yoshiharu Tojo , Toshifumi Yamaai , Ryoh Aruga
发明人： Koji Ishikura , Yoshiharu Tojo , Toshifumi Yamaai , Ryoh Aruga
IPC分类号： G06F40/174 , G06F3/0482 , G06V10/40 , G06V30/10
摘要： An information processing apparatus includes circuitry configured to acquire first form definition information defining a positional relationship between one or more items and a respective value of the one or more items stored in a memory, recognize and extract a specific item set with a specific character string and a specific value of the specific item from data of a form image based on the first form definition information as a recognition result, and display, on a display, the recognition result and an input reception section used for receiving an input of second form definition information.

7. 发明授权

US06214818B1 Cephem compounds and pharmaceutical compositions containing the same 失效
标题翻译： Cephem化合物和含有它们的药物组合物
公开(公告)号：US06214818B1
公开(公告)日：2001-04-10
申请号：US09147074
申请日：1998-10-01
申请人： Yasuhiro Nishitani , Koji Ishikura
发明人： Yasuhiro Nishitani , Koji Ishikura
IPC分类号： C07D50146
CPC分类号： C07D401/04 , C07D409/04 , C07D501/00
摘要： A cephem compound, wherein the cephem ring has a substituent at the 3-position, which substituent is shown by the formula II, wherein Het is a mono- or polycyclic heterocyclic group comprising one or more hetero atoms selected from the group consisting of N, O and S which may be the same or different from each other; R1 is hydrogen, an optionally substituted lower alkyl or an optionally substituted lower alkenyl; A is an optionally substituted lower alkylene, an optionally substituted lower alkenylene or a single bond; B is an optionally substituted imino or a single bond; or A and B taken together may form a single bond; and D is a single bond or a group of the formula (a): The cephem compounds of the present invention are useful as antibiotic agents.
摘要翻译：头孢烯化合物，其中头孢烯环在3位具有取代基，该取代基由式II表示，其中Het是包含一个或多个选自N， O和S可以相同或不同; R 1为氢，任选取代的低级烷基或任选取代的低级烯基; A是任选取代的低级亚烷基，任选取代的低级亚烯基或单键; B是任选取代的亚氨基或单键; 或A和B组合在一起可形成单一债券; 和D是单键或式（a）的基团：本发明的头孢烯化合物可用作抗生素。

8. 发明授权

US09369453B2 Information processing apparatus and information processing system 有权
标题翻译：信息处理装置和信息处理系统
公开(公告)号：US09369453B2
公开(公告)日：2016-06-14
申请号：US14330091
申请日：2014-07-14
申请人： Koji Ishikura
发明人： Koji Ishikura
IPC分类号： H04L29/06
CPC分类号： H04L63/08
摘要： An information processing apparatus includes a user authentication unit that authenticates a user, a data storage controller that controls the storing of data in a network storage and a local storage, a usage history information recording unit that records usage history information for all data stored in the network storage including user information who accessed the data, a prediction unit that predicts data that has a high probability of being accessed by the user based on identification information and the usage history information of the user authenticated by the user authentication unit, and an acquisition unit that acquires the data that has a high probability of being accessed predicted by the prediction unit from the network storage and stores the data in the local storage.
摘要翻译：一种信息处理设备，包括用户认证单元，用于认证用户，控制数据存储在网络存储器和本地存储器中的数据存储控制器;使用历史信息记录单元，其记录存储在所述存储器中的所有数据的使用历史信息网络存储器，包括访问数据的用户信息;预测单元，其基于识别信息和由用户认证单元认证的用户的使用历史信息来预测用户访问的概率很高的数据;以及获取单元其从网络存储器获取由预测单元预测的访问概率很高的数据，并将数据存储在本地存储器中。

9. 发明授权

US06458950B1 Compounds and pharmaceutical compositions containing the same 失效
标题翻译：含有它们的化合物和药物组合物
公开(公告)号：US06458950B1
公开(公告)日：2002-10-01
申请号：US09631947
申请日：2000-08-03
申请人： Yasuhiro Nishitani , Koji Ishikura
发明人： Yasuhiro Nishitani , Koji Ishikura
IPC分类号： C07D40104
CPC分类号： C07D401/04 , C07D409/04 , C07D501/00
摘要： A compound shown by the formula II, wherein Het is a mono- or polycyclic heterocyclic group comprising one or more hetero atoms selected from the group consisting of N, O and S which may be the same or different from each other; R1 is hydrogen, an optionally substituted lower alkyl or an optionally substituted lower alkenyl; A is an optionally substituted lower alkylene, an optionally substituted lower alkenylene or a single bond; B is an optionally substituted imino or a single bond; or A and B taken together may form a single bond; and D is a single bond or a group of the formula (a):
摘要翻译：式II所示的化合物，其中Het是包含一个或多个选自N，O和S中的可以彼此相同或不同的杂原子的单环或多环杂环基; R 1为氢，任选取代的低级烷基或任选取代的低级烯基; A是任选取代的低级亚烷基，任选取代的低级亚烯基或单键; B是任选取代的亚氨基或单键; 或A和B组合在一起可形成单一债券; 和D是单键或式（a）的基团：

10. 发明授权

US11151373B2 Information processing apparatus and information processing method 有权
公开(公告)号：US11151373B2
公开(公告)日：2021-10-19
申请号：US16503794
申请日：2019-07-05
申请人： Yoshiharu Tojo , Toshifumi Yamaai , Koji Ishikura , Fumihiro Teshima
发明人： Yoshiharu Tojo , Toshifumi Yamaai , Koji Ishikura , Fumihiro Teshima
IPC分类号： G06K9/00 , G06K9/34
摘要： An information processing apparatus includes processing circuitry. The circuitry acquires first ledger sheet definition information and second ledger sheet definition information from a memory. The first ledger sheet definition information defines relative positions of an item and a value of the item in a ledger sheet. The second ledger sheet definition information defines relative positions of an item and a value of the item in a ledger sheet unique to a user. Based on at least one of the first ledger sheet definition information and the second ledger sheet definition information, the circuitry extracts an item and a value of the item from reading result information that associates a character string read from a ledger sheet image with information representing a position of the character string, and the circuitry outputs the extracted item and value of the item as a recognition result.

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