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1. 发明授权

US6040439A Method for chemical synthesis of oligonucleotides 失效
标题翻译：寡核苷酸的化学合成方法
公开(公告)号：US6040439A
公开(公告)日：2000-03-21
申请号：US145973
申请日：1998-09-03
申请人： Yoshihiro Hayakawa , Masanori Kataoka
发明人： Yoshihiro Hayakawa , Masanori Kataoka
IPC分类号： C07D233/58 , C07D235/08 , C07H1/00 , C07H19/04 , C07H21/00
CPC分类号： C07H21/00 , C07H19/04
摘要： The present invention provides a practical method capable of chemically synthesizing a 100-mer or more long-chain oligonucleotide easily and reliably and a novel compound used in said method. The present invention relates to a method for chemical synthesis of an oligonucleotide by the phosphoroamidite method, which comprises preparing a base moiety-unprotected nucleoside phosphoroamidite from a base moiety-unprotected nucleoside by use of an imidazole trifluoromethanesulfonate represented by the following chemical formula, and coupling said base moiety-unprotected nucleotide phosphoroamidite in a predetermined order to chemically synthesize an oligonucleotide consisting of a specific nucleotide sequence, as well as to an imidazole trifluoromethanesulfonate represented by the chemical formula. ##STR1##
摘要翻译：本发明提供了能够容易且可靠地化学合成100聚体或更多长链寡核苷酸的实用方法和用于所述方法的新型化合物。本发明涉及通过亚磷酰胺方法化学合成寡核苷酸的方法，其包括通过使用由以下化学式表示的咪唑三氟甲磺酸盐从碱部分未保护的核苷制备碱基部分未保护的核苷亚磷酰胺，以及偶联所述碱基部分未保护的核苷酸亚磷酰胺以预定的顺序化学合成由特定核苷酸序列组成的寡核苷酸，以及由化学式表示的咪唑三氟甲磺酸盐。

2. 发明申请

US20100036108A1 Universal Base 有权
标题翻译：通用基地
公开(公告)号：US20100036108A1
公开(公告)日：2010-02-11
申请号：US12064858
申请日：2006-07-27
申请人： Masanori Kataoka
发明人： Masanori Kataoka
IPC分类号： C07H1/00 , C07D487/00
CPC分类号： C07H1/00 , C07F7/1804
摘要： The present invention provides artificial universal base capable of base pairing nonspecifically with any of four kinds of natural nucleic acid bases (A, T, G, and C) without the function to specifically recognize pairing natural nucleic acid bases for base pair formation.Universal base capable of base paring nonspecifically with four kinds of natural nucleic acid bases, wherein the universal base has a structure represented by the following chemical formula: wherein R represents a monovalent group other than a hydrogen atom.
摘要翻译：本发明提供能够与四种天然核酸碱基（A，T，G和C）中的任何一种非特异性碱基配对而不具体识别配对天然核酸碱基用于碱基对形成的人造通用碱。能够与四种天然核酸碱基非特异性碱基对应的通用碱基，其中通式碱具有由下列化学式表示的结构：其中R表示氢原子以外的一价基团。

3. 发明授权

US08492536B2 Method for modifying nucleic acid bases, and nucleic acid base-modified product 有权
标题翻译：核酸碱基修饰方法和核酸碱基修饰产物
公开(公告)号：US08492536B2
公开(公告)日：2013-07-23
申请号：US12672649
申请日：2008-08-08
申请人： Masanori Kataoka , Kuniaki Nagayama
发明人： Masanori Kataoka , Kuniaki Nagayama
IPC分类号： C07H21/00
CPC分类号： C07H21/00 , C12Q1/6806 , C12Q2565/519 , C12Q2563/149 , C12Q2525/113 , C12Q2525/117
摘要： A method for modifying nucleic acid bases by a chemical means, which enables the discrimination of every base species in plural species of bases in a nucleic acid comprising plural nucleotide units, while retaining the base sequence information of the nucleic acid. A nucleic acid base-modified product provided by the method. The nucleic acid base-modified product is essentially a single strand. In accordance with the invention, a novel means for sequencing a nucleic acid by a microscopic means is provided.
摘要翻译：一种通过化学方法修饰核酸碱基的方法，其能够在保留核酸的碱基序列信息的同时，在包含多个核苷酸单元的核酸中区分多种碱基中的每种碱基种类。通过该方法提供的核酸碱基改性产物。核酸碱基改性产物基本上是单链。根据本发明，提供了一种通过微观方法对核酸进行测序的新方法。

4. 发明授权

US06983306B1 Inter-device cooperative control method 失效
标题翻译：设备间协同控制方法
公开(公告)号：US06983306B1
公开(公告)日：2006-01-03
申请号：US09650138
申请日：2000-08-29
申请人： Shigetoshi Sameshima , Katsumi Kawano , Koichi Sano , Motohisa Funabashi , Masanori Kataoka
发明人： Shigetoshi Sameshima , Katsumi Kawano , Koichi Sano , Motohisa Funabashi , Masanori Kataoka
IPC分类号： G06F15/16 , G06F9/46
CPC分类号： G05B15/02 , H04L12/2803 , H04L12/2807
摘要： The present invention relates to a distributed system in which processors incorporated in machines and objects are mutually linked in operation, and an object of the present invention is to provide a distributed system in which each device can establish a link with a suitable device according to changes in the environment and conditions, independently from the system configuration controlled by a server.In order to achieve the above object, each device provided by the present invention obtains information on surrounding devices through a sensor 131 or communication processing 112, recognizes the environment around it through environment recognition processing 111, and stores the environmental information in an environment management table 123. By employing link control processing 113, each device shares conditional information stored in a profile 122 and a policy 124 of each device through the communication processing 112. Each device locally and continuously determines a device to be linked with it or whether to perform a link operation requested by another device, using the shared conditional information, information on the surrounding environment, and the policy 124. The results of a link operation are made public and shared by each device through the link control processing 113, and used for narrowing the range of link target devices.
摘要翻译：本发明涉及其中并入机器和对象的处理器在操作中相互链接的分布式系统，本发明的目的是提供一种分布式系统，其中每个设备可以根据变化与适当的设备建立链接在环境和条件下，独立于由服务器控制的系统配置。为了实现上述目的，本发明提供的每个设备通过传感器131或通信处理112获得关于周围设备的信息，通过环境识别处理111识别周围的环境，并将环境信息存储在环境管理表 123。通过采用链路控制处理113，每个设备通过通信处理112共享存储在配置文件122中的条件信息和每个设备的策略124。每个设备本地并连续地确定要与其链接的设备或者是否使用共享条件信息，关于周围环境的信息和策略124执行另一个设备请求的链路操作。链接操作的结果通过链接控制处理113公开并由每个设备共享，并且用于缩小链接目标设备的范围。

5. 发明授权

US08211899B2 Artificial nucleic acid bases and their use in base pairing natural nucleic acid bases 有权
标题翻译：人造核酸碱基及其在天然核酸碱基配对中的应用
公开(公告)号：US08211899B2
公开(公告)日：2012-07-03
申请号：US12064858
申请日：2006-07-27
申请人： Masanori Kataoka
发明人： Masanori Kataoka
IPC分类号： A01N43/90 , A61K31/519 , C07D487/00
CPC分类号： C07H1/00 , C07F7/1804
摘要： The present invention provides artificial universal base capable of base pairing nonspecifically with any of four kinds of natural nucleic acid bases (A, T, G, and C) without the function to specifically recognize pairing natural nucleic acid bases for base pair formation.Universal base capable of base paring nonspecifically with four kinds of natural nucleic acid bases, wherein the universal base has a structure represented by the following chemical formula: wherein R represents a monovalent group other than a hydrogen atom.
摘要翻译：本发明提供能够与四种天然核酸碱基（A，T，G和C）中的任何一种非特异性碱基配对而不具体识别配对天然核酸碱基用于碱基对形成的人造通用碱。能够与四种天然核酸碱基非特异性碱基对应的通用碱基，其中通式碱具有由下列化学式表示的结构：其中R表示氢原子以外的一价基团。

6. 发明申请

US20100222563A1 METHOD FOR MODIFICATION OF NUCLEOTIDES IN NUCLEIC ACID, AND NUCLEIC ACID HAVING MODIFIED NUCLEOTIDE THEREIN 有权
标题翻译：核酸核酸修饰方法及其改性核酸的核酸
公开(公告)号：US20100222563A1
公开(公告)日：2010-09-02
申请号：US12672649
申请日：2008-08-08
申请人： Masanori Kataoka , Kuniaki Nagayama
发明人： Masanori Kataoka , Kuniaki Nagayama
IPC分类号： C07H19/20 , C07H1/00 , C07H21/00 , C07H19/04
CPC分类号： C07H21/00 , C12Q1/6806 , C12Q2565/519 , C12Q2563/149 , C12Q2525/113 , C12Q2525/117
摘要： A method for modifying nucleic acid bases by a chemical means, which enables the discrimination of every base species in plural species of bases in a nucleic acid comprising plural nucleotide units, while retaining the base sequence information of the nucleic acid. A nucleic acid base-modified product provided by the method. The nucleic acid base-modified product is essentially a single strand. In accordance with the invention, a novel means for sequencing a nucleic acid by a microscopic means is provided.
摘要翻译：一种通过化学方法修饰核酸碱基的方法，其能够在保留核酸的碱基序列信息的同时，在包含多个核苷酸单元的核酸中区分多种碱基中的每种碱基种类。通过该方法提供的核酸碱基改性产物。核酸碱基改性产物基本上是单链。根据本发明，提供了一种通过微观方法对核酸进行测序的新方法。

7. 发明授权

US07978698B2 Terminal for performing multiple access transmission suitable to a transmission path having varied characteristics 有权
标题翻译：用于执行适合于具有不同特性的传输路径的多址传输的终端
公开(公告)号：US07978698B2
公开(公告)日：2011-07-12
申请号：US12282947
申请日：2007-03-16
申请人： Tsuyoshi Yamaguchi , Yuji Igata , Yasushi Yokomitsu , Toru Yasukawa , Shinichiro Ohmi , Koji Ikeda , Masanori Kataoka , Junji Yano , Go Kuroda
发明人： Tsuyoshi Yamaguchi , Yuji Igata , Yasushi Yokomitsu , Toru Yasukawa , Shinichiro Ohmi , Koji Ikeda , Masanori Kataoka , Junji Yano , Go Kuroda
IPC分类号： H04L12/28 , H04L12/56
CPC分类号： H04L12/18 , H04L47/15
摘要： A terminal for performing multiple access transmission suitable to a transmission path having varied characteristics includes a transmission/reception section, a control unit, a transfer management section, and an external interface section. Specifically, the terminal refers to an IGMP (MLD) message received by the transmission/reception section to classify a transmitter host and a relay device of the message based on a characteristic of the transmission path, and performs a multiple access transmission of a multicast packet in a form suitable to the characteristic of the transmission path.
摘要翻译：用于执行适合于具有不同特性的传输路径的多址传输的终端包括发送/接收部分，控制单元，传送管理部分和外部接口部分。具体地说，终端是指发送接收部接收到的IGMP（MLD）消息，用于基于传输路径的特性对发送方主机和中继装置进行分类，并进行组播分组的多址传输以适合于传输路径特性的形式。

8. 发明申请

US20090257432A1 TERMINAL 有权
标题翻译：终奌站
公开(公告)号：US20090257432A1
公开(公告)日：2009-10-15
申请号：US12282947
申请日：2007-03-16
申请人： Tsuyoshi Yamaguchi , Yuji Igata , Yasushi Yokomitsu , Toru Yasukawa , Shinichiro Ohmi , Koji Ikeda , Masanori Kataoka , Junji Yano , Go Kuroda
发明人： Tsuyoshi Yamaguchi , Yuji Igata , Yasushi Yokomitsu , Toru Yasukawa , Shinichiro Ohmi , Koji Ikeda , Masanori Kataoka , Junji Yano , Go Kuroda
IPC分类号： H04L12/56
CPC分类号： H04L12/18 , H04L47/15
摘要： Provides a terminal for performing multiple access transmission suitable to a transmission path having varied characteristics. The terminal (100) includes a transmission/reception section (201), a control unit (204), a transfer management section (206), and an external interface section (203). The terminal (100) refers to an IGMP (MLD) message received by the transmission/reception section (201) to classify a transmitter host and a relay device of this message based on the characteristic of the transmission path, and performs a multiple access transmission of a multicast packet in a form suitable to the characteristic of the respective transmission path.
摘要翻译：提供用于执行适合于具有不同特性的传输路径的多址传输的终端。终端（100）包括发送/接收部分（201），控制单元（204），传送管理部分（206）和外部接口部分（203）。终端（100）是指由发送接收部（201）接收到的IGMP（MLD）消息，用于基于传输路径的特性对发送方主机和中继装置进行分类，并进行多址传输以适合于相应传输路径的特性的形式的组播分组。

9. 发明授权

US07010583B1 Transport system 失效
标题翻译：运输系统
公开(公告)号：US07010583B1
公开(公告)日：2006-03-07
申请号：US09645450
申请日：2000-08-25
申请人： Takeiki Aizono , Makoto Shioya , Teruji Sekozawa , Koichi Sano , Masanori Kataoka
发明人： Takeiki Aizono , Makoto Shioya , Teruji Sekozawa , Koichi Sano , Masanori Kataoka
IPC分类号： G06F15/16 , G08G1/123
CPC分类号： G08G1/096716 , G08G1/096783 , G08G1/205
摘要： A transport system composed of road side stations installed along roads and vehicles running on roads, wherein emergency processing at the time of an accident, a local information providing service, and so on are realized by the road side stations in cooperation of the road side stations and the respective vehicles. In the transport system, a plurality of road side stations are interconnected through a road side communication network, and a plurality of vehicles communicate with the road side stations. A vehicle transmits a request message containing a service code and location information. A road side station receiving the request message broadcasts the request message to the network. The road side stations receive the message, and determine whether or not requested processing should be executed based on the service code and the location information. When determining that the processing should be executed, the road side station executes processing indicated by the service code.
摘要翻译：由道路上安装的道路站和道路上行驶的车辆组成的运输系统，事故发生时的紧急处理，本地信息提供服务等，由路侧站和各自的车辆。在运输系统中，多个道路侧站通过路侧通信网络互连，并且多个车辆与道路站进行通信。车辆发送包含服务码和位置信息的请求消息。接收请求消息的道路侧站向网络广播请求消息。路侧站接收消息，并且基于服务代码和位置信息来确定是否应该执行请求的处理。当确定执行处理时，路侧站执行由服务代码指示的处理。

10. 发明授权

US06697836B1 Method and apparatus for controlling server 失效
标题翻译：用于控制服务器的方法和装置
公开(公告)号：US06697836B1
公开(公告)日：2004-02-24
申请号：US09153873
申请日：1998-09-16
申请人： Shigeki Kawano , Junichi Toyouchi , Motohisa Funabashi , Masanori Kataoka , Katsumi Kawano , Linda Strick
发明人： Shigeki Kawano , Junichi Toyouchi , Motohisa Funabashi , Masanori Kataoka , Katsumi Kawano , Linda Strick
IPC分类号： G06F1516
CPC分类号： H04L67/101 , H04L67/1002 , H04L67/1012 , H04L67/1034
摘要： A client (referred to as A) transmits a request to a service mediate server (referred to as B) through a communication medium. B receives information. A server (referred to as C) receives a request for obtaining information from B and transmits information requested by B. B receives a request from A. A service mediate managing unit determines a type of information to be provided to A, based on the attribute information of the content of the request, the customized information of A and C pre-stored in the service mediate managing unit, and various status at the receipt of the request. The service mediate agent selects any one of plural Cs and transmit the request for obtaining information to the selected C. The information received by C is processed by the service mediate agent and the processed information is transmitted to A.
摘要翻译：客户机（称为A）通过通信介质向服务中介服务器（称为B）发送请求。 B收到信息。服务器（称为C）接收从B获取信息的请求并发送由B请求的信息.B从A接收请求。服务调停管理单元基于属性确定要提供给A的信息的类型请求的内容的信息，预先存储在服务中介管理单元中的A和C的定制信息以及在接收请求时的各种状态。服务中介代理选择多个Cs中的任何一个，并向所选择的C发送获取信息的请求.C接收到的信息由服务中介代理处理，处理后的信息被发送到A.

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