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1. 发明申请

US20100256118A1 NOVEL ADENINE COMPOUND AND USE THEREOF 失效
标题翻译：新颖的化合物及其用途
公开(公告)号：US20100256118A1
公开(公告)日：2010-10-07
申请号：US12793649
申请日：2010-06-03
申请人： Yoshiaki ISOBE , Haruo Takaku , Haruhisa Ogita , Masanori Tobe , Ayumu Kurimoto , Tetsuhiro Ogino , Hitoshi Fujita
发明人： Yoshiaki ISOBE , Haruo Takaku , Haruhisa Ogita , Masanori Tobe , Ayumu Kurimoto , Tetsuhiro Ogino , Hitoshi Fujita
IPC分类号： A61K31/52 , C07D473/18 , A61K31/5377 , C07D473/24 , C07D473/16 , A61K31/55 , A61P11/06 , A61P17/00 , A61P37/02
CPC分类号： A61K31/5377 , A61K31/522 , A61K31/55
摘要： A drug for topically administration which is effective as an antiallergic agent. The drug for topically administration contains as an active ingredient an adenine compound represented by the general formula (1): [wherein ring A represents a 6 to 10 membered, mono or bicyclic, aromatic hydrocarbon or a 5 to 10 membered, mono or bicyclic, aromatic heterocycle containing one to three heteroatoms selected among 0 to 2 nitrogen atoms, 0 or 1 oxygen atom, and 0 or 1 sulfur atom; n is an integer of 0 to 2; m is an integer of 0 to 2; R represents halogeno, (un)substituted alkyl, etc.; X1 represents oxygen, sulfur, NR1 (R1 represents hydrogen or alkyl), or a single bond; Y1 represents a single bond, alkylene, etc.; Y2 represents a single bond, alkylene, etc.; Z represents alkylene; and at least one of Q1 and Q2 represents —COOR10 (wherein R10 represents (un)substituted alkyl, etc.), etc.] or a pharmaceutically acceptable salt of the compound.
摘要翻译：用作局部给药的药物，其作为抗过敏剂有效。用于局部给药的药物含有作为活性成分的由通式（1）表示的腺嘌呤化合物：[其中环A表示6至10元，单或双环，芳族烃或5至10元，单或双环，含有1至3个选自0至2个氮原子，0或1个氧原子和0或1个硫原子的杂原子的芳族杂环; n为0〜2的整数， m为0〜2的整数; R代表卤代，（取代）烷基等; X1代表氧，硫，NR1（R1代表氢或烷基）或单键; Y1表示单键，亚烷基等; Y2表示单键，亚烷基等; Z表示亚烷基; 并且Q1和Q2中的至少一个表示-COOR 10（其中R 10表示（un）取代的烷基等）等）或该化合物的药学上可接受的盐。

2. 发明申请

US20120178743A1 NOVEL ADENINE COMPOUND AND USE THEREOF 审中-公开
标题翻译：新颖的化合物及其用途
公开(公告)号：US20120178743A1
公开(公告)日：2012-07-12
申请号：US13402850
申请日：2012-02-22
申请人： Yoshiaki ISOBE , Haruo Takaku , Haruhisa Ogita , Masanori Tobe , Ayumu Kurimoto , Tetsuhiro Ogino , Hitoshi Fujita
发明人： Yoshiaki ISOBE , Haruo Takaku , Haruhisa Ogita , Masanori Tobe , Ayumu Kurimoto , Tetsuhiro Ogino , Hitoshi Fujita
IPC分类号： A61K31/52 , A61K31/5377 , A61P37/08 , A61P37/00 , A61P31/12 , A61P17/00 , C07D473/18 , A61K31/55
CPC分类号： A61K31/5377 , A61K31/522 , A61K31/55
摘要： An antiallergic agent for topical administration containing an adenine compound of general formula (1): [wherein ring A represents a 6 to 10 membered, mono or bicyclic, aromatic hydrocarbon or a 5 to 10 membered, mono or bicyclic, aromatic heterocycle containing one to three heteroatoms selected among 0 to 2 nitrogen atoms, 0 or 1 oxygen atom, and 0 or 1 sulfur atom; n is an integer of 0 to 2; m is an integer of 0 to 2; R represents halogeno, (un)substituted alkyl, etc.; X1 represents oxygen, sulfur, NR1 (R1 represents hydrogen or alkyl), or a single bond; Y1 represents a single bond, alkylene, etc.; Y2 represents a single bond, alkylene, etc.; Z represents alkylene; and at least one of Q1 and Q2 represents —COOR10 (wherein R10 represents (un)substituted alkyl, etc.), etc.] or a pharmaceutically acceptable salt of the compound.
摘要翻译：一种用于局部给药的抗过敏剂，其含有通式（1）的腺嘌呤化合物：[其中环A表示6至10元，单或双环，芳烃或5至10元单或双环芳族杂环，选自0至2个氮原子，0或1个氧原子和0或1个硫原子的3个杂原子; n为0〜2的整数， m为0〜2的整数; R代表卤代，（取代）烷基等; X1代表氧，硫，NR1（R1代表氢或烷基）或单键; Y1表示单键，亚烷基等; Y2表示单键，亚烷基等; Z表示亚烷基; 并且Q1和Q2中的至少一个表示-COOR 10（其中R 10表示（un）取代的烷基等）等）或该化合物的药学上可接受的盐。

3. 发明申请

US20080178262A1 AUTHENTICATION SYSTEM MANAGING METHOD 失效
标题翻译：认证系统管理方法
公开(公告)号：US20080178262A1
公开(公告)日：2008-07-24
申请号：US11949159
申请日：2007-12-03
申请人： Kazuhiko TANIGUCHI , Yoshiaki ISOBE , Nariyasu HAMADA , Hiroyuki SHIMIZU
发明人： Kazuhiko TANIGUCHI , Yoshiaki ISOBE , Nariyasu HAMADA , Hiroyuki SHIMIZU
IPC分类号： G06F21/00
CPC分类号： G07C9/00166 , G06F21/32 , G06K9/00926 , G06K9/00993 , G07C9/00158
摘要： Inputted information (such as biometric information) is compared to template information (including correlation or authentication) and the result is recorded as log information. According to log information for each of the types of the inputted information (such as information specifying the user who has inputted it and the template), analysis is executed for the inputted information for each of the types. This analysis includes the following aspects. That is, the following states are detected and an alarm is outputted for the accuracy of the corresponding type: when the ratio of negative comparison results (correlation failures) not smaller than a predetermined value is detected within a predetermined period of time; and when a negative result is detected within a predetermined time before an affirmative comparison result is obtained.
摘要翻译：将输入信息（如生物特征信息）与模板信息（包括相关或认证）进行比较，并将结果记录为日志信息。根据输入信息的每种类型（诸如指定输入的用户的信息和模板）的日志信息，针对每种类型的输入信息执行分析。该分析包括以下几个方面。也就是说，检测到以下状态并为相应类型的精度输出报警：当在预定时间段内检测到不小于预定值的负比较结果（相关故障）的比率时; 并且当在获得肯定比较结果之前的预定时间内检测到否定结果时。

4. 发明申请

US20110028715A1 NOVEL ADENINE COMPOUND 审中-公开
标题翻译：新颖的化合物
公开(公告)号：US20110028715A1
公开(公告)日：2011-02-03
申请号：US12905012
申请日：2010-10-14
申请人： Yoshiaki ISOBE , Tomoaki NAKAMURA
发明人： Yoshiaki ISOBE , Tomoaki NAKAMURA
IPC分类号： C07D401/14 , C07D473/02 , C07D413/14
CPC分类号： C07D473/24 , C07D473/00 , C07D473/16 , C07D473/18 , C07D473/34
摘要： A novel adenine compound represented by the formula (1): wherein A represents an (un)substituted aromatic carbocycle or (un)substituted aromatic heterocycle; L1 and L2 each independently represents straightened or branched alkylene, etc.; R1 represents halogen, (un)substituted alkyl, (un)substituted alkenyl, (un)substituted alkynyl, (un)substituted cycloalkyl, (un)substituted aryl, or (un)substituted heteroaryl; R2 and R3 each independently represents hydrogen, or (un)substituted alkyl, (un)substituted alkenyl, (un)substituted alkynyl, (un)substituted cycloalkyl, (un)substituted saturated heterocycle, (un)substituted aryl, or (un)substituted heteroaryl, or R2 combines together with L2 or R3 to form (un)substituted 4- to 8-membered nitrogen-containing saturated heterocycle; X is oxygen, sulfur, SO, SO2, NR7, NR7CO wherein R7 is hydrogen or alkyl, or a single bond; provided that X is a single bond when R1 is halogen, or a pharmaceutically acceptable salt thereof. The compound and salt are useful as a medicine.
摘要翻译：由式（1）表示的新型腺嘌呤化合物：其中A表示（un）取代的芳族碳环或（un）取代的芳族杂环; L1和L2各自独立地表示直链或支链亚烷基等; R 1表示卤素，（未）取代的烷基，（未）取代的烯基，（未）取代的炔基，（未）取代的环烷基，（未）取代的芳基或（未）取代的杂芳基; R2和R3各自独立地表示氢，或（未）取代的烷基，（未）取代的烯基，（未）取代的炔基，（未）取代的环烷基，（未）取代的饱和杂环，（未）取代的芳基或（未）或R 2与L 2或R 3一起形成（未）取代的4-至8-元含氮饱和杂环; X是氧，硫，SO，SO 2，NR 7，NR 7 CO，其中R 7是氢或烷基，或单键; 条件是当R 1为卤素时X为单键，或其药学上可接受的盐。化合物和盐可用作药物。

5. 发明申请

US20110138187A1 SYSTEM AND METHOD OF BIOMETRIC AUTHENTICATION USING MULTIPLE KINDS OF TEMPLATES 失效
标题翻译：使用多种模板的生物识别系统和方法
公开(公告)号：US20110138187A1
公开(公告)日：2011-06-09
申请号：US12873729
申请日：2010-09-01
申请人： Yosuke KAGA , Osamu TAKATA , Yoshiaki ISOBE , Kenta TAKAHASHI , Takao MURAKAMI
发明人： Yosuke KAGA , Osamu TAKATA , Yoshiaki ISOBE , Kenta TAKAHASHI , Takao MURAKAMI
IPC分类号： G06F21/00
CPC分类号： G06F21/32 , G06F2221/2117
摘要： In additional enrollment of a template in a biometric authentication system, the template is automatically enrolled on the basis of a plurality of authentication results to assure a user's convenience and security. A post-migration authentication server receives a first template and a second template from a post-migration authentication terminal, performs authentication on the basis of the comparison result between the received first template and the user's preliminarily first enrolled template, and provisionally enrolls the first template and the second template. It repeats the reception, authentication, and provisional enrollment and calculates a match probability from a plurality of comparison results of the provisionally first enrolled templates, determines whether or not to store a second enrolled template on the basis of the match probability, and automatically enrolls the second template in the post-migration authentication server.
摘要翻译：在生物认证系统中额外登记模板时，基于多个认证结果自动注册该模板，以确保用户的便利性和安全性。迁移后认证服务器从迁移后认证终端接收第一模板和第二模板，根据接收到的第一模板与用户的初始登录模板之间的比较结果进行认证，并临时登记第一模板和第二个模板。它重复接收，认证和临时注册，并根据临时第一登记模板的多个比较结果计算匹配概率，基于匹配概率确定是否存储第二登记模板，并自动注册后迁移认证服务器中的第二个模板。

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