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1. 发明授权

US07211406B2 Potassium channel 有权
标题翻译：钾通道
公开(公告)号：US07211406B2
公开(公告)日：2007-05-01
申请号：US10451892
申请日：2001-12-26
申请人： Hiromichi Yokoi , Kohei Inamura , Yorikata Sano , Akira Miyake , Shinobu Mochizuki
发明人： Hiromichi Yokoi , Kohei Inamura , Yorikata Sano , Akira Miyake , Shinobu Mochizuki
IPC分类号： G01N33/566 , C07K14/705 , C07H21/04 , C12N15/11 , C12N5/16
CPC分类号： G01N33/5023 , C07K14/705 , G01N33/5008 , G01N33/507 , G01N33/6872 , G01N33/6893 , G01N2500/00
摘要： A novel polypeptide which is useful in searching for a therapeutic agent for diabetes, a polynucleotide encoding the polypeptide, an expression vector comprising the polynucleotide, a cell transfected with the expression vector, an antibody binding to the polypeptide, and a method of screening a therapeutic agent for diabetes are disclosed.The polypeptide is a novel background potassium channel expressed in the pancreas.
摘要翻译：可用于寻找糖尿病治疗剂的新型多肽，编码多肽的多核苷酸，包含多核苷酸的表达载体，用表达载体转染的细胞，与多肽结合的抗体以及筛选治疗剂的方法披露糖尿病药物。该多肽是在胰腺中表达的新型背景钾通道。

2. 发明授权

US07097990B2 Method of screening cell death inhibitor 失效
标题翻译：筛选细胞死亡抑制剂的方法
公开(公告)号：US07097990B2
公开(公告)日：2006-08-29
申请号：US10492477
申请日：2002-08-08
申请人： Yorikata Sano , Kohei Inamura , Akira Miyake , Hiromichi Yokoi , Katsura Nozawa , Shinobu Mochizuki
发明人： Yorikata Sano , Kohei Inamura , Akira Miyake , Hiromichi Yokoi , Katsura Nozawa , Shinobu Mochizuki
IPC分类号： C07K14/705 , G01N33/68 , C12N15/12 , C12N15/63 , C12N15/79 , C12N15/85
CPC分类号： G01N33/507 , G01N33/5008 , G01N33/566 , G01N2500/10 , G01N2510/00
摘要： There is provided a method of screening for substance that inhibits cell death induced by activation of PARP, particularly a substance that is useful as a therapeutic and/or preventive agent for rheumatoid arthritis, neuronal death at the time of cerebral ischemia, cell death of the heart after myocardial infarction reperfusion, autoimmune destruction of β-cells of pancreatic islets of Langerhans, cell death after shock, or inflammatory reaction by immunocyte death. Also provided are a novel protein and a novel gene encoding the same. The aforementioned screening method comprises a step of allowing a test substance to contact a cell expressing an LTRPC2 protein under a conditions such that the LTRPC2 protein can be activated, and a step of analyzing inhibition of LTRPC2 protein activation. The aforementioned novel protein is a rat or mouse LTRPC2 protein, and the aforementioned novel gene is a rat or mouse LTRPC2 gene.
摘要翻译：提供了一种筛选抑制由PARP活化诱导的细胞死亡的物质的方法，特别是可用作类风湿性关节炎的治疗和/或预防剂，脑缺血时的神经元死亡，细胞死亡心肌梗死再灌注后心脏，胰岛胰岛β细胞自身免疫破坏，休克后细胞死亡或免疫细胞死亡引起炎症反应。还提供了一种新的蛋白质和编码该蛋白质的新基因。上述筛选方法包括在使LTRPC2蛋白可被活化的条件下，使测试物质接触表达LTRPC2蛋白的细胞的步骤，以及分析LTRPC2蛋白活化的抑制的步骤。上述新型蛋白质是大鼠或小鼠LTRPC2蛋白，上述新型基因是大鼠或小鼠LTRPC2基因。

3. 发明授权

US07476508B2 Method of screening agent for improving memory and learning ability 失效
标题翻译：筛选剂提高记忆力和学习能力的方法
公开(公告)号：US07476508B2
公开(公告)日：2009-01-13
申请号：US10542560
申请日：2004-01-16
申请人： Yorikata Sano , Kohei Inamura , Shinobu Mochizuki
发明人： Yorikata Sano , Kohei Inamura , Shinobu Mochizuki
IPC分类号： G01N33/53 , G01N33/566 , G01N33/48 , G01N31/00 , G01N25/18
CPC分类号： C07K14/705
摘要： A screening tool and a screening method of a substance which is useful as an agent for improving the memory, an agent for improving learning ability, and/or an antidementia agent; a polypeptide, a polynucleotide, a vector, and a cell which may be used in the above screening; and a novel agent for improving the memory, a novel agent for improving learning ability, and/or a novel antidementia agent are disclosed. The above screening tool is composed of a calcium-permeable nonselective cation channel or a cell expressing the channel.
摘要翻译：可用作改善记忆的药剂的物质的筛选工具和筛选方法，提高学习能力的药剂和/或抗增殖剂; 可用于上述筛选的多肽，多核苷酸，载体和细胞; 和用于提高记忆力的新型药剂，提高学习能力的新型药剂和/或新型抗增殖剂。上述筛选工具由钙渗透性非选择性阳离子通道或表达通道的细胞组成。

4. 发明申请

US20060116315A1 Method of screening agent for improving memory and learning ability 失效
公开(公告)号：US20060116315A1
公开(公告)日：2006-06-01
申请号：US10542560
申请日：2004-01-16
申请人： Yorikata Sano , Kohei Inamura , Shinobu Mochizuki
发明人： Yorikata Sano , Kohei Inamura , Shinobu Mochizuki
IPC分类号： A61K38/17 , C07K14/705 , G01N33/567
CPC分类号： C07K14/705
摘要： A screening tool and a screening method of a substance which is useful as an agent for improving the memory, an agent for improving learning ability, and/or an antidementia agent; a polypeptide, a polynucleotide, a vector, and a cell which may be used in the above screening; and a novel agent for improving the memory, a novel agent for improving learning ability, and/or a novel antidementia agent are disclosed. The above screening tool is composed of a calcium-permeable nonselective cation channel or a cell expressing the channel.

5. 发明授权

US08780107B2 Image processing apparatus for displaying image on display unit and control method thereof 有权
标题翻译：用于在显示单元上显示图像的图像处理装置及其控制方法
公开(公告)号：US08780107B2
公开(公告)日：2014-07-15
申请号：US13155888
申请日：2011-06-08
申请人： Yuki Shindo , Kohei Inamura
发明人： Yuki Shindo , Kohei Inamura
IPC分类号： G06T15/00 , H04N5/202 , G06K9/00
CPC分类号： G06T15/00 , G06K9/00 , G06T5/009 , G06T5/40 , G06T2207/10021 , H04N1/624 , H04N5/202 , H04N13/133
摘要： A frequency of each gradation in an image for the left eye histogram is compared with a frequency of each gradation in an image for the right eye histogram. An integration histogram is generated using at least a larger one of the frequency of each gradation in the image for the left eye histogram and the frequency of each gradation in the image for the right eye histogram. A gradation correction parameter is set based on the generated integration histogram. The gradations of the image for the left eye and the image for the right eye are corrected using the gradation correction parameter.
摘要翻译：将用于左眼直方图的图像中的每个灰度的频率与用于右眼直方图的图像中的每个灰度的频率进行比较。使用左眼直方图的图像中的每个灰度的频率中的至少较大的一个以及用于右眼直方图的图像中的每个灰度的频率来生成积分直方图。基于生成的积分直方图来设置灰度校正参数。使用灰度校正参数校正左眼图像和右眼图像的灰度。

6. 发明授权

US07190410B2 Color temperature correction circuit 失效
标题翻译：色温校正电路
公开(公告)号：US07190410B2
公开(公告)日：2007-03-13
申请号：US10887829
申请日：2004-07-12
申请人： Kohei Inamura
发明人： Kohei Inamura
IPC分类号： H04N9/73
CPC分类号： H04N9/73
摘要： Denoting a maximum value of three primary color signals RGB by Max, a minimum value by Min, and coefficients by a and b, the color temperature of only colors close to achromatic colors is changed by adding (a*Min−b*Max) to the signal B. Denoting a luminance level by Y, and coefficients by c and d, the color temperature of only colors close to achromatic colors is changed by adding (c*Y−d*(Max−Min)) to the signal B. Color temperature of only colors close to achromatic colors is changed by multiplying the signal B by a coefficient based on a value of (Man−Min)/Max, which represents saturation.
摘要翻译：通过将最大值三分之一以RGB表示为最大值，最小值为Min，系数为a和b，通过将（a * Min-b * Max）加到（a * Min-b * Max）中来改变接近无彩色的仅有颜色的色温信号B.通过将亮度等级设为Y，通过c和d表示系数，通过向信号B添加（c * Yd *（Max-Min））来改变接近无彩色的仅有颜色的色温。色温通过将信号B乘以基于表示饱和度的（Man-Min）/ Max的值的系数来改变仅接近消色差的颜色。

7. 发明授权

US07079161B2 Image display apparatus 失效
公开(公告)号：US07079161B2
公开(公告)日：2006-07-18
申请号：US10164400
申请日：2002-06-10
申请人： Osamu Sagano , Naoto Abe , Kohei Inamura , Hiroshi Saito , Takeshi Ikeda
发明人： Osamu Sagano , Naoto Abe , Kohei Inamura , Hiroshi Saito , Takeshi Ikeda
IPC分类号： G09G5/10 , G09G5/00
CPC分类号： G09G3/22 , G09G3/2014 , G09G2310/0259 , G09G2320/0209 , G09G2320/0223
摘要： There is here provided an image display apparatus that adjusts a change of a drive condition resulting from an electrical resistance of a matrix wiring of a display panel scarcely using a hardware.The apparatus has an adjusted image data calculation unit that generates adjusted image data that is the image data to which adjustment is applied for relaxing an influence of a voltage drop caused by the electrical resistance of a row wiring for the input image data of one horizontal scan interval, wherein the adjusted image data calculation unit is provided with means for discretely forecasting and calculating a voltage drop amount in the space and time directions, to be generated on the row wiring during the one horizontal scan interval corresponding to input image data and means for calculating the adjusted image data in which adjustment is applied to the image data.

8. 发明申请

US20060017718A1 Image display apparatus 失效
公开(公告)号：US20060017718A1
公开(公告)日：2006-01-26
申请号：US11234094
申请日：2005-09-26
申请人： Osamu Sagano , Naoto Abe , Kohei Inamura , Hiroshi Saito , Takeshi Ikeda
发明人： Osamu Sagano , Naoto Abe , Kohei Inamura , Hiroshi Saito , Takeshi Ikeda
IPC分类号： G09G5/00
CPC分类号： G09G3/22 , G09G3/2014 , G09G2310/0259 , G09G2320/0209 , G09G2320/0223
摘要： There is here provided an image display apparatus that adjusts a change of a drive condition resulting from an electrical resistance of a matrix wiring of a display panel scarcely using a hardware. The apparatus has an adjusted image data calculation unit that generates adjusted image data that is the image data to which adjustment is applied for relaxing an influence of a voltage drop caused by the electrical resistance of a row wiring for the input image data of one horizontal scan interval, wherein the adjusted image data calculation unit is provided with means for discretely forecasting and calculating a voltage drop amount in the space and time directions, to be generated on the row wiring during the one horizontal scan interval corresponding to input image data and means for calculating the adjusted image data in which adjustment is applied to the image data.

9. 发明授权

US06873308B2 Image display apparatus 失效
标题翻译：图像显示装置
公开(公告)号：US06873308B2
公开(公告)日：2005-03-29
申请号：US10188892
申请日：2002-07-05
申请人： Osamu Sagano , Naoto Abe , Kohei Inamura , Hiroshi Saito , Takeshi Ikeda
发明人： Osamu Sagano , Naoto Abe , Kohei Inamura , Hiroshi Saito , Takeshi Ikeda
IPC分类号： G09G3/20 , G09G3/22
CPC分类号： G09G3/22 , G09G3/2014 , G09G2320/0223 , G09G2320/0276 , G09G2320/0285 , G09G2320/0606 , G09G2320/0626 , G09G2360/144
摘要： The present invention is to provide an image display apparatus capable of properly correcting or adjusting, with small-scale hardware, variations in drive conditions due to electric resistance of matrix wiring on a display panel. The image display apparatus includes an adjusted image data calculation unit 14 for calculating adjusted image data as image data that has been compensated for the influence of voltage drop caused by resistance of at least the row wiring and a scan unit. The image display apparatus also includes an amplitude adjustment unit having a function for adjusting the amplitude of adjusted image data Dout, and a modulator 8 the takes in the adjusted image data with the amplitude adjusted and outputs a modulation signal to the column wiring.
摘要翻译：本发明提供一种图像显示装置，能够以小尺寸的硬件正确地校正或调整由于显示面板上的矩阵布线的电阻而导致的驱动条件的变化。图像显示装置包括：调整图像数据计算单元14，用于计算调整后的图像数据，作为补偿由至少行布线和扫描单元的电阻引起的电压降的影响的图像数据。图像显示装置还包括具有用于调整调整图像数据Dout的振幅的功能的幅度调整单元和调制器8，调制器8调整调整后的图像数据并将调制信号输出到列布线。

10. 发明授权

US06590617B1 Edge emphasis device, image forming apparatus, image signal processing method, and image forming method 失效
标题翻译：边缘强调装置，图像形成装置，图像信号处理方法和图像形成方法
公开(公告)号：US06590617B1
公开(公告)日：2003-07-08
申请号：US09507942
申请日：2000-02-22
申请人： Izumi Kanai , Yukio Hiraki , Kohei Inamura
发明人： Izumi Kanai , Yukio Hiraki , Kohei Inamura
IPC分类号： H04N5208
CPC分类号： H04N5/208
摘要： This invention can suppress overshoot/undershoot, and can maintain the improvement effect of the leading edge of an edge portion. For this purpose, a second derivative signal generator (1) generates a second derivative signal (s5) on the basis of time-serially input three successive pixels. A second derivative signal suppression unit (2) generates a signal (s8) obtained by suppressing the second derivative signal, and a signal (s9) indicating the sign of the second derivative signal. The absolute values of the differences between the pixel of interest, and its neighboring pixels are computed, and a smaller one of the absolute values is selected as a signal (s14) by a minimum value selection circuit (18). By multiplying the obtained signals (s8, s9, s14) by a multiplier (19), an edge-emphasizing signal (s15) is generated. The edge-emphasizing signal (s15) is added to the signal of the pixel of interest by an adder (20), thus obtaining an edge-emphasized signal s16.
摘要翻译：本发明可以抑制过冲/下冲，并且可以保持边缘部分的前缘的改善效果。为此，二阶导数信号发生器（1）基于时间顺序输入三个连续的像素产生二阶导数信号（s5）。第二导数信号抑制单元（2）产生通过抑制二次微分信号获得的信号（s8）和表示二阶导数信号的符号的信号（s9）。计算感兴趣像素与其相邻像素之间的差异的绝对值，并且通过最小值选择电路（18）将绝对值中较小的绝对值选择为信号（s14）。通过将所获得的信号（s8，s9，s14）乘以乘法器（19），产生边缘强调信号（s15）。通过加法器（20）将边缘加重信号（s15）加到感兴趣像素的信号上，从而获得边缘强调信号s16。

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