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1. 发明申请

US20120172890A1 BIRTH DELIVERY DEVICE WITH POSITION SENSOR 有权
标题翻译：具有位置传感器的生物交付装置
公开(公告)号：US20120172890A1
公开(公告)日：2012-07-05
申请号：US13395446
申请日：2010-09-13
申请人： Yoav Paltieli
发明人： Yoav Paltieli
IPC分类号： A61B17/42
CPC分类号： A61B17/442 , A61B17/42 , A61B17/44 , A61B34/20 , A61B2034/102
摘要： A birth delivery device (10, 30) including one or more engaging elements (18, 32) shaped to engage a fetal head, one or more handles (19, 40) connected to the one or more engaging elements (18, 32) that manipulate the one or more engaging elements (18, 32), and one or more position sensors (20) placed on a portion of at least one of the engaging elements (18, 32) and the handles (19, 40), the position sensors (20) being in communication with a processor (22) that processes data from the position sensors (20) to determine positional information related to the fetal head.
摘要翻译：包括形成为接合胎儿头部的一个或多个接合元件（18,32）的出生递送装置（10,30），连接到所述一个或多个接合元件（18,32）的一个或多个手柄（19,40），操纵一个或多个接合元件（18,32）以及放置在至少一个接合元件（18,32）和把手（19,40）的一部分上的一个或多个位置传感器（20），位置传感器（20）与处理器（22）通信，处理器（22）处理来自位置传感器（20）的数据，以确定与胎儿头部相关的位置信息。

2. 发明申请

US20080167553A1 Method and Apparatus For Monitoring Labor Parameter 有权
标题翻译：监测劳动参数的方法和装置
公开(公告)号：US20080167553A1
公开(公告)日：2008-07-10
申请号：US10567344
申请日：2004-08-06
申请人： Yoav Paltieli , Octavian Soldea , Ran Bar-Sella , Gal Ben-David
发明人： Yoav Paltieli , Octavian Soldea , Ran Bar-Sella , Gal Ben-David
IPC分类号： A61B8/00 , A61B5/103 , G06T7/60
CPC分类号： A61B5/6838 , A61B5/061 , A61B5/1076 , A61B5/4362 , A61B5/6826 , A61B8/0833 , A61B8/0866 , G06T7/0012 , G06T7/12 , G06T7/149 , G06T2207/10132 , G06T2207/20116 , G06T2207/30044 , Y10S128/916
摘要： A method for early detection of a pregnancy complication, including touching a position sensor to a point on a fetal presenting part of a fetus in a mother, and capturing a position of the position sensor, touching the position sensor to a set of points on the mother and capturing the position of the position sensor at each point, and detecting a pregnancy complication sign based upon a predefined criterion for said pregnancy complication. Methods and apparatus are provided for identifying the BPD pattern in an ultrasound image, for determining characteristics of body parts outside of a pelvic region, for BPD reconstruction and for an adapter for a position sensor are also described among other embodiments.
摘要翻译：一种用于早期检测妊娠并发症的方法，包括将位置传感器触及到在母亲中呈现胎儿部分胎儿的点，以及捕获所述位置传感器的位置，将所述位置传感器接触到所述位置传感器上的一组点母亲并且捕获每个点处位置传感器的位置，并且基于用于所述妊娠并发症的预定义标准来检测妊娠并发症征兆。还提供了用于识别超声图像中的BPD图案的方法和装置，用于确定骨盆区域外部的身体部位的特征，用于BPD重建以及用于位置传感器的适配器。

3. 发明授权

US5807264A Endoscope apparatus and method for detecting cilia motion using multimode detection fibers to collect back-scattered light 失效
标题翻译：使用多模检测光纤检测纤毛运动的内窥镜装置和方法来收集反向散射光
公开(公告)号：US5807264A
公开(公告)日：1998-09-15
申请号：US632334
申请日：1996-04-10
申请人： Yoav Paltieli
发明人： Yoav Paltieli
IPC分类号： A61B5/00 , A61B5/11
CPC分类号： A61B5/0084 , A61B5/411
摘要： An endoscope apparatus for detecting cilia motion while examining the interior of a body. The endoscope apparatus including a long slender tube having a probe tip at one end, which is inserted into the body to be examined. First, second and third optical fibers extend through the tube to the probe tip. A source of light at the opposite end of the tube aligned with the first optical fiber for transmitting light into the body via the probe tip. Light detectors are at the opposite end of the tube, one in alignment with each of the second and third optical fibers, for receiving light transmitted therethrough back-scattered from the interior of the body. A differential measuring element for differentially measuring the outputs of the two detectors such as to substantially cancel out artifacts and to increase the signal-to-noise ratio. The differential measuring element operates in a frequency range of 0.5-30 Hz in order to detect the range of frequencies of typical cilia beats.
摘要翻译：一种用于检测身体内部的纤毛运动的内窥镜装置。所述内窥镜装置包括长细长管，所述长细管的一端具有探针尖端，所述细长管被插入到被检体内。首先，第二和第三光纤通过管延伸到探针尖端。管的相对端处的光源与第一光纤对准，用于经由探针尖端将光透射到体内。光检测器位于管的相对端，一个与第二和第三光纤中的每一个对准，用于接收从身体内部向后散射的透射光。差分测量元件，用于差分测量两个检测器的输出，以便基本上消除假象并提高信噪比。差分测量元件在0.5-30 Hz的频率范围内工作，以便检测典型纤毛节拍的频率范围。

4. 发明授权

US07211405B2 Placental protein 13 失效
标题翻译：胎盘蛋白13
公开(公告)号：US07211405B2
公开(公告)日：2007-05-01
申请号：US10287639
申请日：2002-11-05
申请人： Arie Admon , Yoav Paltieli , Ronit Slotky , Silvia Mandel
发明人： Arie Admon , Yoav Paltieli , Ronit Slotky , Silvia Mandel
IPC分类号： G01N33/567 , A61K38/00 , C07K2/00 , C07H21/04
CPC分类号： C07K14/4715 , Y10S435/97 , Y10S436/807 , Y10S436/817 , Y10S436/822 , Y10S436/824
摘要： The full amino acid and DNA sequences of placental protein 13 (PP13) are disclosed. Also described are various PP13 derived peptide fragments, and a recombinant method for the production of PP13. PP13 may be used in a screening and a diagnostic method for pregnancy-related complications.
摘要翻译：公开了胎盘蛋白13（PP13）的全部氨基酸和DNA序列。还描述了各种PP13衍生肽片段和用于生产PP13的重组方法。 PP13可用于妊娠相关并发症的筛查和诊断方法。

5. 发明授权

US06200279B1 Method and apparatus monitoring the progress of labor 失效
标题翻译：监测劳动进度的方法和设备
公开(公告)号：US06200279B1
公开(公告)日：2001-03-13
申请号：US09072850
申请日：1998-05-05
申请人： Yoav Paltieli
发明人： Yoav Paltieli
IPC分类号： A61B5103
CPC分类号： A61B5/1076 , A61B5/435 , A61B8/0866
摘要： A method of monitoring the progress of labor in a mother during childbirth, by attaching a position sensor to a predetermined point on the mother's pelvic bones; monitoring the location of the position sensor in three- dimensional space relative to a reference; and monitoring the location of the fetal presenting part with respect to the predetermined point on the mother's pelvic bones. The location of the fetal presenting part may be indicated by a similar position sensor, or by imaging. Other conditions, such as effacement, cervical dilatation, and cervical position may also be monitored in a similar manner.
摘要翻译：通过将位置传感器附接到母亲骨盆上的预定点来监测分娩期间母亲的劳动进度的方法; 在相对于参考的三维空间中监视位置传感器的位置; 并且监测胎儿呈现部分相对于母亲骨盆骨骼上的预定点的位置。胎儿呈现部分的位置可以由相似的位置传感器或通过成像来指示。也可以以类似的方式监测其他情况，例如消除，子宫颈扩张和颈部位置。

6. 发明授权

US5647373A Articulated needle guide for ultrasound imaging and method of using same 失效
标题翻译：用于超声成像的铰接针导向器及其使用方法
公开(公告)号：US5647373A
公开(公告)日：1997-07-15
申请号：US333800
申请日：1994-11-03
申请人： Yoav Paltieli
发明人： Yoav Paltieli
IPC分类号： A61B8/00 , A61B8/08 , A61B10/00 , A61B10/02 , A61B17/34 , A61B19/00
CPC分类号： A61B8/4218 , A61B34/70 , A61B8/00 , A61B8/0833 , A61B8/0841 , A61B10/0233 , A61B17/3403 , A61B2017/3409 , A61B2090/3983 , A61B34/10 , A61B8/4472
摘要： An apparatus configured to direct a medical needle onto a target inside a living body as indicated by an ultrasound imaging device includes an ultrasound transducer and a needle guide holding the medical needle, both attached to a vertical post by movable arms, an ultrasound imaging device and a computer-controller. The arms are provided with links connected by universal joints which permit positioning by the physician of the transducer and the needle guide in any place on the body in the desired direction. The position of the components is indicated to the computer controller by sensors mounted in the joints of the arms or by wireless transmission. The transducer issues signals regarding the target point to the imaging device which transmits the information to the computer controller, the latter adjusting the angular direction of the needle trajectory onto the target. The physician places the transducer on the body in accordance with the image of the target projected on the screen of the imaging device, and places the needle point on the skin close to the target, whereupon the direction of the needle trajectory is automatically adjusted by the apparatus.
摘要翻译：一种被配置为将医用针引导到超声波成像装置所示的生物体内的靶上的装置，包括超声波换能器和保持医用针的针引导件，两者均通过活动臂附接到立柱上，超声波成像装置和一台电脑控制器。臂设置有通过万向接头连接的链节，其允许换能器的医师和针引导件沿着所需方向在身体上的任何位置定位。组件的位置通过安装在臂的关节中的传感器或通过无线传输指示给计算机控制器。传感器发出关于成像装置的目标点的信号，该成像装置将信息发送到计算机控制器，计算机控制器将针轨迹的角度方向调整到目标上。医生根据投影在成像装置的屏幕上的目标的图像将感应器放置在身体上，并将针尖放置在靠近目标的皮肤上，由此针轨迹的方向由仪器。

7. 发明授权

US07850625B2 Method and apparatus for monitoring labor parameter 有权
标题翻译：监测劳动参数的方法和装置
公开(公告)号：US07850625B2
公开(公告)日：2010-12-14
申请号：US10567344
申请日：2004-08-06
申请人： Yoav Paltieli , Octavian Soldea , Ran Bar-Sella , Gal Ben-David
发明人： Yoav Paltieli , Octavian Soldea , Ran Bar-Sella , Gal Ben-David
IPC分类号： A61B5/103
CPC分类号： A61B5/6838 , A61B5/061 , A61B5/1076 , A61B5/4362 , A61B5/6826 , A61B8/0833 , A61B8/0866 , G06T7/0012 , G06T7/12 , G06T7/149 , G06T2207/10132 , G06T2207/20116 , G06T2207/30044 , Y10S128/916
摘要： A method for early detection of a pregnancy complication, including touching a position sensor to a point on a fetal presenting part of a fetus in a mother, and capturing a position of the position sensor, touching the position sensor to a set of points on the mother and capturing the position of the position sensor at each point, and detecting a pregnancy complication sign based upon a predefined criterion for said pregnancy complication. Methods and apparatus are provided for identifying the BPD pattern in an ultrasound image, for determining characteristics of body parts outside of a pelvic region, for BPD reconstruction and for an adapter for a position sensor are also described among other embodiments.
摘要翻译：一种用于早期检测妊娠并发症的方法，包括将位置传感器触及到在母亲中呈现胎儿部分胎儿的点，以及捕获所述位置传感器的位置，将所述位置传感器接触到所述位置传感器上的一组点母亲并且捕获每个点处位置传感器的位置，并且基于用于所述妊娠并发症的预定义标准来检测妊娠并发症征兆。还提供了用于识别超声图像中的BPD图案的方法和装置，用于确定骨盆区域外部的身体部位的特征，用于BPD重建以及用于位置传感器的适配器。

8. 发明授权

US06790625B1 Antibodies to placental protein 13 失效
标题翻译：胎盘蛋白13的抗体
公开(公告)号：US06790625B1
公开(公告)日：2004-09-14
申请号：US09937706
申请日：2002-02-21
申请人： Yoav Paltieli , Lev Rabinovitch
发明人： Yoav Paltieli , Lev Rabinovitch
IPC分类号： G01N33543
CPC分类号： C07K16/18 , Y10S435/975
摘要： A monoclonal antibody (Mab) capable of binding Placental Protein 13 (pp-13) is disclosed. Also disclosed are hybridoma clone producing the Mab, an immunoassay using the Mab for measuring the level of PP-13 in a biological fluid, and a kit for measuring the level of PP-13 in a biological fluid.
摘要翻译：公开了能够结合胎盘蛋白13（pp-13）的单克隆抗体（Mab）。还公开了产生Mab的杂交瘤克隆，使用Mab测量生物流体中PP-13的水平的免疫测定，以及用于测量生物流体中PP-13水平的试剂盒。

9. 发明授权

US06604404B2 Calibration method and apparatus for calibrating position sensors on scanning transducers 失效
标题翻译：用于校准扫描传感器上的位置传感器的校准方法和装置
公开(公告)号：US06604404B2
公开(公告)日：2003-08-12
申请号：US09950644
申请日：2001-09-13
申请人： Yoav Paltieli , Ron Nagar , David Taran
发明人： Yoav Paltieli , Ron Nagar , David Taran
IPC分类号： G01N2900
CPC分类号： A61B8/587 , A61B8/0833 , A61B17/3403 , A61B34/20 , A61B2017/00725 , A61B2017/3413 , A61B2034/107 , A61B2034/2051 , A61B2034/2055 , A61B2034/2068 , A61B2090/363 , A61B2090/378 , G01S7/5205
摘要： There are disclosed systems for calibrating a first position measuring component on an imaging or scanning transducer with respect to the scanning plane. Calibrations are performed by using a calibrating device including an additional or second position measuring component, such that during the calibration process, the relative position of between these position measuring components can be calculated. Calibrations are also performed by viewing targets on the scanning plane that are at a known position with respect to the second position measuring component. Calibrations are also performed based on the to scanning plane and position measuring component on a guided device, such as a needle, that typically is used in conjunction with the imaging or scanning transducer. Methods for these calibrations are also disclosed.
摘要翻译：公开了用于校准相对于扫描平面的成像或扫描换能器上的第一位置测量部件的系统。校准通过使用包括附加或第二位置测量部件的校准装置来执行，使得在校准过程期间，可以计算这些位置测量部件之间的相对位置。还可以通过在扫描平面上观察相对于第二位置测量部件处于已知位置的目标来执行校准。还可以基于通常与成像或扫描换能器结合使用的引导装置（例如针）上的扫描平面和位置测量部件进行校准。还公开了这些校准的方法。

10. 发明授权

US06311540B1 Calibration method and apparatus for calibrating position sensors on scanning transducers 失效
标题翻译：用于校准扫描传感器上的位置传感器的校准方法和装置
公开(公告)号：US06311540B1
公开(公告)日：2001-11-06
申请号：US09566948
申请日：2000-05-08
申请人： Yoav Paltieli , Ron Nagar , David Taran
发明人： Yoav Paltieli , Ron Nagar , David Taran
IPC分类号： G01N2900
CPC分类号： A61B8/587 , A61B8/0833 , A61B17/3403 , A61B34/20 , A61B2017/00725 , A61B2017/3413 , A61B2034/107 , A61B2034/2051 , A61B2034/2055 , A61B2034/2068 , A61B2090/363 , A61B2090/378 , G01S7/5205
摘要： There are disclosed systems for calibrating a first position measuring component on an imaging or scanning transducer with respect to the scanning plane. Calibrations are performed by using a calibrating device including an additional or second position measuring component, such that during the calibration process, the relative position of between these position measuring components can be calculated. Calibrations are also performed by viewing targets on the scanning plane that are at a known position with respect to the second position measuring component. Calibrations are also performed based on the scanning plane and position measuring components on a guided device, such as a needle, that typically is used in conjunction with the imaging or scanning transducer. Methods for these calibrations are also disclosed.
摘要翻译：公开了用于校准相对于扫描平面的成像或扫描换能器上的第一位置测量部件的系统。校准通过使用包括附加或第二位置测量部件的校准装置来执行，使得在校准过程期间，可以计算这些位置测量部件之间的相对位置。还可以通过在扫描平面上观察相对于第二位置测量部件处于已知位置的目标来执行校准。还可以基于通常与成像或扫描换能器结合使用的引导装置（例如针）上的扫描平面和位置测量部件进行校准。还公开了这些校准的方法。

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