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1. 发明申请

US20120207679A1 Novel Heteroaryl Substituted Benzothiazoles 有权
标题翻译：新型杂芳基取代苯并噻唑
公开(公告)号：US20120207679A1
公开(公告)日：2012-08-16
申请号：US13453579
申请日：2012-04-23
申请人： Ylva Gravenfors , Catrin Jonasson , Jonas Malmström , Gunnar Nordvall , David Pyring , Can Slivo , Daniel Sohn , Peter Ström , David Wensbo
发明人： Ylva Gravenfors , Catrin Jonasson , Jonas Malmström , Gunnar Nordvall , David Pyring , Can Slivo , Daniel Sohn , Peter Ström , David Wensbo
IPC分类号： A61K51/04 , A61K31/496 , C07D417/04 , A61P25/28 , A61K31/444 , A61K31/506 , A61K31/5377 , C07F7/18 , C07D417/14 , A61K31/4439
CPC分类号： C07D417/04 , C07B59/002 , C07D513/04
摘要： The present invention relates to novel heteroaryl substituted benzothiazole derivatives, precursors thereof, and therapeutic uses for such compounds, having the structural formula (I) below: and to their pharmaceutically acceptable salt, compositions and methods of use. Furthermore, the invention relates to novel heteroaryl substituted benzothiazole derivatives that are suitable for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents.
摘要翻译：本发明涉及新颖的杂芳基取代的苯并噻唑衍生物，其前体，以及具有以下结构式（I）的化合物及其药学上可接受的盐，组合物和使用方法的治疗用途。此外，本发明涉及适用于在活体患者中成像淀粉样蛋白沉积物的新型杂芳基取代的苯并噻唑衍生物，其组合物，使用方法和制备此类化合物的方法。更具体地说，本发明涉及一种在体内淀粉样蛋白沉积物在体内成像以使阿尔茨海默病的止血诊断成为可能并测量阿尔茨海默病治疗剂的临床疗效的方法。

2. 发明授权

US07245045B2 T-filter for reducing disturbances generated on a power grid by an active filter 有权
标题翻译： T滤波器，用于减少有源滤波器在电网上产生的干扰
公开(公告)号：US07245045B2
公开(公告)日：2007-07-17
申请号：US10490016
申请日：2002-09-18
申请人： Peter Ström , Dan Liljengren
发明人： Peter Ström , Dan Liljengren
IPC分类号： H02M1/12
CPC分类号： H02M7/2173 , H02J3/01 , Y02E40/40
摘要： An active filter (4) for compensation of variations in an apparatus' (3) current consumption from a power grid (1) as a cause of variations in the apparatus electrical load, through active frequency filtering and dynamic compensation of reactive energy/current. For each of the power grid's phases (a, b, c) the active filter includes a transistor bridge (Ta, Tb, Tc) connected between each phase and a DC-link (7). The active filter includes a filter circuit of LCL-type, arranged to reduce disturbances on the power grid caused by the active filter itself. The active filter further includes a control device (9) for calculating, with a given working frequency (f), points in time at which the transistor bridges are set to reverse the current direction through the DC-link, and the filter circuit is preferably adjusted to that working frequency.
摘要翻译：一种有源滤波器（4），用于通过有源频率滤波和无功电能/电流的动态补偿来补偿装置（3）电力系统（3）的电流消耗的变化，作为设备电气负载变化的原因。对于每个电网的相位（a，b，c），有源滤波器包括连接在每个相位和DC链路（7）之间的晶体管桥（Ta，Tb，Tc）。有源滤波器包括LCL型滤波器电路，其布置成减少由有源滤波器本身引起的电网干扰。有源滤波器还包括控制装置（9），用于以给定的工作频率（f）计算晶体管桥被设置为使通过DC链路的电流方向反向的时间点，并且滤波器电路优选地调整到工作频率。

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