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1. 发明授权

US08877719B2 Pest controlling composition 有权
标题翻译：害虫控制组成
公开(公告)号：US08877719B2
公开(公告)日：2014-11-04
申请号：US13388303
申请日：2010-07-30
申请人： Yasutaka Shimokawatoko , Emiko Sakamoto , Mayuko Ozawa
发明人： Yasutaka Shimokawatoko , Emiko Sakamoto , Mayuko Ozawa
IPC分类号： A61K31/70 , A01N43/22
CPC分类号： A01N43/22 , A01N43/12 , A01N47/06 , A01N2300/00
摘要： A pest controlling composition comprising spinetoram and a cyclic keto-enol compound having an acetyl CoA carboxylase-inhibiting activity as active ingredients.
摘要翻译：一种害虫控制组合物，其包含具有乙酰辅酶A羧化酶抑制活性作为活性成分的旋风振荡和环酮酮 - 烯醇化合物。

2. 发明申请

US20120129796A1 PEST CONTROLLING COMPOSITION 有权
标题翻译：病虫害控制组合物
公开(公告)号：US20120129796A1
公开(公告)日：2012-05-24
申请号：US13388303
申请日：2010-07-30
申请人： Yasutaka Shimokawatoko , Emiko Sakamoto , Mayuko Ozawa
发明人： Yasutaka Shimokawatoko , Emiko Sakamoto , Mayuko Ozawa
IPC分类号： A01N43/04 , A01P15/00
CPC分类号： A01N43/22 , A01N43/12 , A01N47/06 , A01N2300/00
摘要： A pest controlling composition comprising spinetoram and a cyclic keto-enol compound having an acetyl CoA carboxylase-inhibiting activity as active ingredients.
摘要翻译：一种害虫控制组合物，其包含具有乙酰辅酶A羧化酶抑制活性作为活性成分的旋风振荡和环酮酮 - 烯醇化合物。

3. 发明申请

US20130029976A1 PEST CONTROLLING COMPOSITION 审中-公开
标题翻译：病虫害控制组合物
公开(公告)号：US20130029976A1
公开(公告)日：2013-01-31
申请号：US13641420
申请日：2011-04-11
申请人： Yasutaka Shimokawatoko
发明人： Yasutaka Shimokawatoko
IPC分类号： A01N43/84 , A01P15/00
CPC分类号： A01N47/38 , A01N43/40 , A01N2300/00
摘要： A pest controlling composition comprising pyridalyl and indoxacarb.
摘要翻译：一种害虫控制组合物，其包含吡啶并吲哚卡巴。

4. 发明授权

US06830926B2 Method for evaluating the ability of a compound to inhibit the protoporphyrinogen oxidase activity 失效
标题翻译：评估化合物抑制原卟啉原氧化酶活性的能力的方法
公开(公告)号：US06830926B2
公开(公告)日：2004-12-14
申请号：US09978709
申请日：2001-10-18
申请人： Yasutaka Shimokawatoko
发明人： Yasutaka Shimokawatoko
IPC分类号： C12N902
CPC分类号： C12N9/0004 , C12Q1/6897
摘要： The present invention provides a method for evaluating the ability of a compound to inhibit protoporphyrinogen oxidase activity, which comprises the steps of (1) culturing a transformant expressing a heterologous protoporphyrinogen oxidase (PPO) gene in a medium containing substantially no protoheme compounds in the presence and absence of a test compound to measure the growth rate of the transformant, wherein the transformant is a host cell deficient in PPO activity which is transformed with the heterologous PPO gene, and (2) determining the ability of the compound to inhibit the protoporphyrinogen oxidase activity by comparing growth rates.
摘要翻译：本发明提供了一种评估化合物抑制原卟啉原氧化酶活性的能力的方法，其包括以下步骤：（1）在存在基本上不含原质化合物的培养基中培养表达异源原卟啉原氧化酶（PPO）基因的转化体并且不存在测试化合物以测量转化体的生长速率，其中转化体是用异源PPO基因转化的PPO活性缺陷的宿主细胞，和（2）测定化合物抑制原卟啉原氧化酶的能力比较增长率的活动。

5. 发明申请

US20130005671A1 PEST CONTROL COMPOSITION 有权
标题翻译：害虫控制组合物
公开(公告)号：US20130005671A1
公开(公告)日：2013-01-03
申请号：US13579681
申请日：2011-02-18
申请人： Yasutaka Shimokawatoko , Katsuya Natsuhara , Tetsuo Tanikawa
发明人： Yasutaka Shimokawatoko , Katsuya Natsuhara , Tetsuo Tanikawa
IPC分类号： A01N43/22 , A01P7/02 , A01P5/00 , A01P7/00 , A01P7/04
CPC分类号： A01N43/22 , A01N2300/00 , A01N25/006 , A01N43/76
摘要： Disclosed is a pest control composition having an excellent controlling effect on pests, which comprises etoxazole and a compound represented by the formula (I): wherein, R1 is a hydrogen atom or a methyl group, R2 is a hydrogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, or a (C1-C4 alkyl)carbonyl group, R3 is a hydrogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, or a (C1-C4 alkyl)carbonyl group, R4 is a hydrogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, or a (C1-C4 alkyl)carbonyl group, R5 is a hydrogen atom, a C1-C4 alkyl group, or a C1-C4 alkylamino group, R6 is a hydrogen atom or a methyl group, R7 is a methyl group or an ethyl group, R8 is an amino group, a C1-C4 alkylamino group, or a di(C1-C4 alkyl)amino group, and X1 and X2 are hydrogen atoms or X1 and X2 together form a single bond.
摘要翻译：本发明公开了一种对害虫具有优异的防治效果的害虫防治用组合物，其特征在于，包括依毒唑和式（I）表示的化合物：其中，R1为氢原子或甲基，R2为氢原子，C1-C4 烷基，C1-C4卤代烷基或（C1-C4烷基）羰基，R3是氢原子，C1-C4烷基，C1-C4卤代烷基或（C1-C4烷基）羰基基团，R4是氢原子，C1-C4烷基，C1-C4卤代烷基或（C1-C4烷基）羰基，R5是氢原子，C1-C4烷基或C1- C4烷基氨基，R6是氢原子或甲基，R7是甲基或乙基，R8是氨基，C1-C4烷基氨基或二（C1-C4烷基）氨基，以及 X1和X2是氢原子或X1和X2一起形成单键。

6. 发明申请

US20120258929A1 AGENT THAT MODULATES PHYSIOLOGICAL CONDITION OF PESTS, INVOLVED IN INSECT PEPTIDYL-DIPEPTIDASE A ACTIVITY 审中-公开
标题翻译：调节生理状况的药剂，涉及胰腺癌细胞活化的参与
公开(公告)号：US20120258929A1
公开(公告)日：2012-10-11
申请号：US11993586
申请日：2006-06-23
申请人： Yasutaka Shimokawatoko , Marc Van De Craen , Irene Nooren , Sandra Turconi , Yann Naudet , Guy Nys , Jurgen Debaveye
发明人： Yasutaka Shimokawatoko , Marc Van De Craen , Irene Nooren , Sandra Turconi , Yann Naudet , Guy Nys , Jurgen Debaveye
IPC分类号： A01N43/08 , A01N43/36 , C07D285/135 , A01N43/824 , C07D225/06 , A01N43/46 , C07J1/00 , A01N45/00 , C07D209/52 , A01N43/38 , C07D217/26 , A01N43/42 , C07H19/067 , C07D277/54 , A01N43/78 , A01P7/04 , C12N15/57 , C12Q1/37 , C12N9/48 , C12Q1/68 , C12N15/66 , C12N5/10 , C12N15/64 , C12N7/01 , C07D207/16
CPC分类号： A01N61/00 , A01N43/36 , A01N43/38 , A01N43/42 , A01N43/46 , A01N45/00 , A01N47/36 , A01N63/00 , C07J41/0038 , C12N9/485 , C12N9/6402 , C12N9/99 , C12N2799/026 , C12Q1/37 , C12Y304/15001 , G01N2500/04
摘要： The present invention provides an agent that modulates physiological condition of pests, wherein the agent has an ability to modulate the activity of an insect peptidyl-dipeptidase A; a method for assaying pesticidal activity of a test substance, which comprises a step of measuring the activity of a peptidyl-dipeptidase A in a reaction system in which the peptidyl-dipeptidase A contacts with a test substance, and the like.
摘要翻译：本发明提供了调节害虫生理状态的试剂，其中该试剂具有调节昆虫肽基二肽酶A活性的能力; 用于测定被检物质的杀虫活性的方法，其包括测定肽基 - 二肽酶A与检测物质接触的反应体系中肽基二肽酶A的活性的步骤等。

7. 发明申请

US20110207775A1 AGENT THAT MODULATES PHYSIOLOGICAL CONDITION OF PESTS, INVOLVED IN INSECT VESICLE-FUSING ATPASE ACTIVITY 审中-公开
标题翻译：调节生物物理条件的代理人，参与疫苗融合ATP酶活性
公开(公告)号：US20110207775A1
公开(公告)日：2011-08-25
申请号：US12515071
申请日：2007-11-19
申请人： Yasutaka Shimokawatoko , Marc Van De Craen , Irene Nooren , Bert Oosthuyse , Bert Demey , Wendy Maddelein , Geraldine Drevon
发明人： Yasutaka Shimokawatoko , Marc Van De Craen , Irene Nooren , Bert Oosthuyse , Bert Demey , Wendy Maddelein , Geraldine Drevon
IPC分类号： A01N43/40 , C12Q1/34 , C12N9/14 , C07H21/00 , C12P19/34 , C12Q1/68 , C12N15/63 , C12N15/66 , C12N1/21 , C12N15/74 , C07C309/52 , A01N47/30 , C07D233/64 , A01N43/50 , C07D211/34 , A01P7/00 , A01P7/04 , A01P7/02 , A01P5/00 , G06F17/30
CPC分类号： C12N9/14 , A01N61/00 , C12Q1/34 , C12Q1/6865 , C12Y306/04006 , G01N33/573 , G01N2333/914 , G01N2500/04 , C12Q2525/307
摘要： The present invention provides an agent that modulates physiological condition of pests, wherein the agent has an ability to modulate the activity of an insect vesicle-fusing ATPase; a method for assaying pesticidal activity of a test substance, which comprises measuring the activity of a vesicle-fusing ATPase in a reaction system in which the vesicle-fusing ATPase contacts with a test substance, and the like.
摘要翻译：本发明提供调节害虫生理状态的试剂，其中该试剂具有调节昆虫泡囊融合ATP酶的活性的能力; 用于测定被检物质的杀虫活性的方法，其包括测定囊泡融合的ATP酶与测试物质接触的反应体系中的囊泡融合的ATP酶的活性等。

8. 发明授权

US06472164B1 Method for evaluating the ability of a compound to inhibit the protoporphyrinogen oxidase activity 失效
标题翻译：评估化合物抑制原卟啉原氧化酶活性的能力的方法
公开(公告)号：US06472164B1
公开(公告)日：2002-10-29
申请号：US09289180
申请日：1999-04-09
申请人： Yasutaka Shimokawatoko , Shoichi Nishio
发明人： Yasutaka Shimokawatoko , Shoichi Nishio
IPC分类号： C12Q126
CPC分类号： C12N9/0004 , C12Q1/6897
摘要： The present invention provides a method for evaluating the ability of a compound to inhibit protoporphyrinogen oxidase activity with a host cell deficient in protoporphyrinogen oxidase production which has been transformed with a vector comprising a DNA fragment encoding a protoporphyrinogen oxidase. Transformed cells are grown in protoheme-free medium in the presence and absence of test compounds and growth rates measured under these condition are compared to determine if inhibition has occurred.
摘要翻译：本发明提供了一种用含有编码原卟啉原氧化酶的DNA片段的载体转化的原卟啉原氧化酶生成缺陷的宿主细胞抑制原卟啉原氧化酶活性的能力的方法。在存在和不存在测试化合物的情况下，将转化的细胞在无原子培养基中生长，并在这些条件下测量的生长速率进行比较，以确定是否发生抑制。

9. 发明授权

US08796231B2 Pest control composition 有权
标题翻译：害虫控制组成
公开(公告)号：US08796231B2
公开(公告)日：2014-08-05
申请号：US13579681
申请日：2011-02-18
申请人： Yasutaka Shimokawatoko , Katsuya Natsuhara , Tetsuo Tanikawa
发明人： Yasutaka Shimokawatoko , Katsuya Natsuhara , Tetsuo Tanikawa
IPC分类号： A61K31/70 , A01N43/22
CPC分类号： A01N43/22 , A01N2300/00 , A01N25/006 , A01N43/76
摘要： Disclosed is a pest control composition having an excellent controlling effect on pests, which comprises etoxazole and a compound represented by the formula (I): wherein, R1 is a hydrogen atom or a methyl group, R2 is a hydrogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, or a (C1-C4 alkyl)carbonyl group, R3 is a hydrogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, or a (C1-C4 alkyl)carbonyl group, R4 is a hydrogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, or a (C1-C4 alkyl)carbonyl group, R5 is a hydrogen atom, a C1-C4 alkyl group, or a C1-C4 alkylamino group, R6 is a hydrogen atom or a methyl group, R7 is a methyl group or an ethyl group, R8 is an amino group, a C1-C4 alkylamino group, or a di(C1-C4 alkyl)amino group, and X1 and X2 are hydrogen atoms or X1 and X2 together form a single bond.
摘要翻译：本发明公开了一种对害虫具有优异的防治效果的害虫防治用组合物，其特征在于，包括依毒唑和式（I）表示的化合物：其中，R1为氢原子或甲基，R2为氢原子，C1-C4 烷基，C1-C4卤代烷基或（C1-C4烷基）羰基，R3是氢原子，C1-C4烷基，C1-C4卤代烷基或（C1-C4烷基）羰基基团，R4是氢原子，C1-C4烷基，C1-C4卤代烷基或（C1-C4烷基）羰基，R5是氢原子，C1-C4烷基或C1- C4烷基氨基，R6是氢原子或甲基，R7是甲基或乙基，R8是氨基，C1-C4烷基氨基或二（C1-C4烷基）氨基，以及 X1和X2是氢原子或X1和X2一起形成单键。

10. 发明申请

US20110053883A1 AGENT THAT MODULATES PHYSIOLOGICAL CONDITION OF PESTS, INVOLVED IN INSECT C-JUN AMINO-TERMINAL KINASE ACTIVITY 审中-公开
标题翻译：调查生物生理状况的代理人，涉及C-Jun的终末性激酶活性
公开(公告)号：US20110053883A1
公开(公告)日：2011-03-03
申请号：US11993602
申请日：2006-06-23
申请人： Yasutaka Shimokawatoko , Mar Van De Craen , Irene Nooren , Sandra Turconi , Annelies Roobrouck , Wendy Maddelein
发明人： Yasutaka Shimokawatoko , Mar Van De Craen , Irene Nooren , Sandra Turconi , Annelies Roobrouck , Wendy Maddelein
IPC分类号： A01N43/90 , C12Q1/48 , C12P19/34 , C12N9/12 , C12N7/01 , C12N5/10 , C12N15/63 , A01N57/36 , A01N43/56 , A01N43/38 , A01N43/30 , A01N41/04 , C07H21/04 , C07H19/19 , C07D487/04 , C07D231/54 , C07D403/14 , C07D493/10 , C07C309/67 , C07F9/6584 , C07H21/00 , A01P7/04
CPC分类号： C12Q1/485 , C12N9/1205
摘要： The present invention provides an agent that modulates physiological condition of pests, wherein the agent has an ability to modulate the activity of an insect c-Jun NH2-terminal kinase; a method for assaying pesticidal activity of a test substance, which comprises a step of measuring the activity of a c-Jun NH2-terminal kinase in a reaction system in which the c-Jun NH2-terminal kinase contacts with a test substance, and the like.
摘要翻译：本发明提供调节害虫生理状态的试剂，其中该试剂具有调节昆虫c-Jun NH 2 - 末端激酶活性的能力; 用于测定被检物质的杀虫活性的方法，其包括测量c-Jun NH 2 - 末端激酶与测试物质接触的反应体系中c-Jun NH 2 - 末端激酶的活性的步骤，以及喜欢。

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