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1. 发明申请

US20120116028A1 METHOD FOR PRODUCING POLYCARBONATE MATERIAL HAVING EXCELLENT SOLUBILITY AND AFFINITY, AND CONTACT LENS MATERIAL COMPRISING THE SAME 失效
标题翻译：生产具有优异溶解性和亲和性的聚碳酸酯材料的方法和包含其的接触透镜材料
公开(公告)号：US20120116028A1
公开(公告)日：2012-05-10
申请号：US13383993
申请日：2009-07-15
申请人： Yasuhiko Suzuki , Kazuhiko Nakada , Tsuyoshi Watanabe , Takahiro Adachi , Mamoru Hagiwara , Masahiko Minemura
发明人： Yasuhiko Suzuki , Kazuhiko Nakada , Tsuyoshi Watanabe , Takahiro Adachi , Mamoru Hagiwara , Masahiko Minemura
IPC分类号： C08L69/00 , C08G64/04
CPC分类号： C08G64/085 , G02B1/043 , C08L69/00 , C08L83/04 , C08L51/085
摘要： According to the present invention, a contact lens material being excellent in oxygen permeability and transparency, being capable of undergoing injection molding, having no water content and having flexibility, as well as a contact lens gel material having excellent oxygen permeability and transparency can be provided. The present invention relates to a contact lens material comprising a polycarbonate resin derived from at least two compounds among compounds represented by a general formula (A), a general formula (B) and a general formula (C), a highly polar molecular weight control modifier (chain terminator) and a compound forming a carbonic acid ester, wherein the compound of the general formula (A) is essentially comprised, and to a production method thereof.
摘要翻译：根据本发明，可以提供透氧性和透明性优异的能够进行注射成型，不含水分并具有柔软性的隐形眼镜材料，以及具有优异的透氧性和透明性的隐形眼镜凝胶材料。本发明涉及一种隐形眼镜材料，其包含由通式（A），通式（B）和通式（C）表示的化合物中的至少两种化合物衍生的聚碳酸酯树脂，高极性分子量控制改性剂（链终止剂）和形成碳酸酯的化合物，其中通式（A）的化合物基本上包括其制备方法。

2. 发明授权

US08710157B2 Contact lens material 失效
标题翻译：隐形眼镜材料
公开(公告)号：US08710157B2
公开(公告)日：2014-04-29
申请号：US13383983
申请日：2009-07-15
申请人： Yasuhiko Suzuki , Kazuhiko Nakada , Tsuyoshi Watanabe , Takahiro Adachi , Mamoru Hagiwara , Masahiko Minemura
发明人： Yasuhiko Suzuki , Kazuhiko Nakada , Tsuyoshi Watanabe , Takahiro Adachi , Mamoru Hagiwara , Masahiko Minemura
IPC分类号： C08F283/02
CPC分类号： C08G64/085 , G02B1/043 , C08L69/00 , C08L83/04 , C08L51/085
摘要： According to the present invention, a contact lens material being excellent in oxygen permeability and transparency, being capable of undergoing injection molding, having no water content and having flexibility is provided. The present invention also relates to a contact lens gel material having excellent oxygen permeability and transparency. Particularly, the present invention relates to a contact lens material comprising a polycarbonate resin derived from a bisphenol compound (A), a polysiloxane-substituted bisphenol compound (B) and a compound forming a carbonic acid ester.
摘要翻译：根据本发明，提供透氧性和透明性优异的能够进行注射成型，不含水分并具有柔性的隐形眼镜材料。本发明还涉及透氧性和透明性优异的隐形眼镜凝胶材料。特别地，本发明涉及包含衍生自双酚化合物（A）的聚碳酸酯树脂，聚硅氧烷取代的双酚化合物（B）和形成碳酸酯的化合物的隐形眼镜材料。

3. 发明授权

US08501878B2 Method for producing polycarbonate material having excellent solubility and affinity, and contact lens material comprising the same 失效
标题翻译：具有优异的溶解性和亲和性的聚碳酸酯材料的制造方法和包含该聚碳酸酯材料的隐形眼镜材料
公开(公告)号：US08501878B2
公开(公告)日：2013-08-06
申请号：US13383993
申请日：2009-07-15
申请人： Yasuhiko Suzuki , Kazuhiko Nakada , Tsuyoshi Watanabe , Takahiro Adachi , Mamoru Hagiwara , Masahiko Minemura
发明人： Yasuhiko Suzuki , Kazuhiko Nakada , Tsuyoshi Watanabe , Takahiro Adachi , Mamoru Hagiwara , Masahiko Minemura
IPC分类号： G02B1/04 , C08L83/06 , C08L67/00
CPC分类号： C08G64/085 , G02B1/043 , C08L69/00 , C08L83/04 , C08L51/085
摘要： According to the present invention, a contact lens material being excellent in oxygen permeability and transparency, being capable of undergoing injection molding, having no water content and having flexibility, as well as a contact lens gel material having excellent oxygen permeability and transparency can be provided. The present invention relates to a contact lens material comprising a polycarbonate resin derived from at least two compounds among compounds represented by a general formula (A), a general formula (B) and a general formula (C), a highly polar molecular weight control modifier (chain terminator) and a compound forming a carbonic acid ester, wherein the compound of the general formula (A) is essentially comprised, and to a production method thereof.
摘要翻译：根据本发明，可以提供透氧性和透明性优异的能够进行注射成型，不含水分并具有柔软性的隐形眼镜材料，以及具有优异的透氧性和透明性的隐形眼镜凝胶材料。本发明涉及一种隐形眼镜材料，其包含由通式（A），通式（B）和通式（C）表示的化合物中的至少两种化合物衍生的聚碳酸酯树脂，高极性分子量控制改性剂（链终止剂）和形成碳酸酯的化合物，其中通式（A）的化合物基本上包括其制备方法。

4. 发明申请

US20120116019A1 CONTACT LENS MATERIAL 失效
标题翻译：接触透镜材料
公开(公告)号：US20120116019A1
公开(公告)日：2012-05-10
申请号：US13383983
申请日：2009-07-15
申请人： Yasuhiko Suzuki , Kazuhiko Nakada , Tsuyoshi Watanabe , Takahiro Adachi , Mamoru Hagiwara , Masahiko Minemura
发明人： Yasuhiko Suzuki , Kazuhiko Nakada , Tsuyoshi Watanabe , Takahiro Adachi , Mamoru Hagiwara , Masahiko Minemura
IPC分类号： G02B1/04 , C08G64/16 , C08G64/38 , C08G77/52
CPC分类号： C08G64/085 , G02B1/043 , C08L69/00 , C08L83/04 , C08L51/085
摘要： According to the present invention, a contact lens material being excellent in oxygen permeability and transparency, being capable of undergoing injection molding, having no water content and having flexibility is provided. The present invention also relates to a contact lens gel material having excellent oxygen permeability and transparency. Particularly, the present invention relates to a contact lens material comprising a polycarbonate resin derived from a compound represented by a general formula (A), a compound represented by a general formula (B) and a compound forming a carbonic acid ester.
摘要翻译：根据本发明，提供透氧性和透明性优异的能够进行注射成型，不含水分并具有柔性的隐形眼镜材料。本发明还涉及透氧性和透明性优异的隐形眼镜凝胶材料。特别地，本发明涉及一种隐形眼镜材料，其包含衍生自由通式（A）表示的化合物的聚碳酸酯树脂，由通式（B）表示的化合物和形成碳酸酯的化合物。

5. 发明授权

US08173720B2 Transparent gel and contact lense from the same 失效
标题翻译：透明凝胶和接触镜从同一个
公开(公告)号：US08173720B2
公开(公告)日：2012-05-08
申请号：US11813781
申请日：2006-01-13
申请人： Kazuhiko Nakada , Takahito Nakase , Takahiro Adachi , Akira Yamamoto , Masahiko Minemura
发明人： Kazuhiko Nakada , Takahito Nakase , Takahiro Adachi , Akira Yamamoto , Masahiko Minemura
IPC分类号： G02C7/04
CPC分类号： C08L69/00 , C08G77/442 , C08G77/448 , C08L33/14 , C08L33/24 , C08L39/06 , C08L83/00 , C08L83/04 , C08L83/10 , C08L2201/00 , G02B1/043 , C08L2666/14 , C08L2666/04 , C08L2666/02
摘要： A transparent gel is disclosed which has an interpenetrating polymer network of a copolymer containing a polysiloxane structure and a polycarbonate structure and a hydrophilic polymer obtained by polymerizing a hydrophilic monomer. The transparent gel is useful as a cultivation substrate, a container for storage and an ophthalmic material, comprising an easily synthesizable and purifiable silicon-containing resin, wherein a gel strength, transparency, oxygen permeability, birefringence and other characteristics are excellent.
摘要翻译：公开了一种透明凝胶，其具有包含聚硅氧烷结构和聚碳酸酯结构的共聚物的互穿聚合物网络和通过聚合亲水性单体获得的亲水性聚合物。透明凝胶可用作培养基质，储存容器和眼科材料，其包含易于合成和可纯化的含硅树脂，其中凝胶强度，透明度，透氧性，双折射性等特性优异。

6. 发明申请

US20090012205A1 TRANSPARENT GEL AND CONTACT LENSE FROM THE SAME 失效
标题翻译：透明的凝胶和与之接触的粘合剂
公开(公告)号：US20090012205A1
公开(公告)日：2009-01-08
申请号：US11813781
申请日：2006-01-13
申请人： Kazuhiko Nakada , Takahito Nakase , Takahiro Adachi , Akira Yamamoto , Masahiko Minemura
发明人： Kazuhiko Nakada , Takahito Nakase , Takahiro Adachi , Akira Yamamoto , Masahiko Minemura
IPC分类号： G02B1/04 , C08L83/06 , C08L67/00
CPC分类号： C08L69/00 , C08G77/442 , C08G77/448 , C08L33/14 , C08L33/24 , C08L39/06 , C08L83/00 , C08L83/04 , C08L83/10 , C08L2201/00 , G02B1/043 , C08L2666/14 , C08L2666/04 , C08L2666/02
摘要： A transparent gel is disclosed which has an interpenetrating polymer network of a copolymer containing a polysiloxane structure and a polycarbonate structure and a hydrophilic polymer obtained by polymerizing a hydrophilic monomer. The transparent gel is useful as a cultivation substrate, a container for storage and an ophthalmic material, comprising an easily synthesizable and purifiable silicon-containing resin, wherein a gel strength, transparency, oxygen permeability, birefringence and other characteristics are excellent.
摘要翻译：公开了一种透明凝胶，其具有包含聚硅氧烷结构和聚碳酸酯结构的共聚物的互穿聚合物网络和通过聚合亲水性单体获得的亲水性聚合物。透明凝胶可用作培养基质，储存容器和眼科材料，其包含易于合成和可纯化的含硅树脂，其中凝胶强度，透明度，透氧性，双折射性等特性优异。

7. 发明授权

US08523878B2 Method of producing medical instrument 有权
标题翻译：医疗器械生产方法
公开(公告)号：US08523878B2
公开(公告)日：2013-09-03
申请号：US12864074
申请日：2008-12-17
申请人： Kohsuke Satake , Kazuharu Niwa , Ryo Matsushita , Yasuhiko Suzuki , Hiroko Nomura , Kazuhiko Nakada
发明人： Kohsuke Satake , Kazuharu Niwa , Ryo Matsushita , Yasuhiko Suzuki , Hiroko Nomura , Kazuhiko Nakada
IPC分类号： A61F9/00 , A61F2/16 , A61L33/00
CPC分类号： A61F2/1664 , A61F2/0077 , A61F2/1675 , A61L29/085 , A61L31/10 , C09D101/14 , C09D101/32
摘要： A method of producing a medical instrument whereby a highly hydrophilic and lubricant coating layer having a high durability can be formed by a simple technique and thus highly hydrophilic and lubricant properties can be imparted to a surface of a medical instrument. An intraocular lens insertion instrument having been subjected to a surface treatment as described above is also provided. The method includes preparing a coating solution by mixing at least a water-insoluble polymer having carboxyl group and a polyfunctional reactive compound with an organic solvent; applying this solution on the surface of the medical instrument; conducting crosslinking; and performing a chemical reaction process. The coating layer is made hydrophilic. The intraocular lens insertion instrument is made hydrophilic by forming the coating layer as described above on an inner surface of an insertion tube portion, crosslinking and then performing the chemical reaction process.
摘要翻译：通过简单的技术可以形成具有高耐久性的高亲水性和润滑性涂层的医疗器械的制造方法，能够赋予医疗器械表面更高的亲水性和润滑性。还提供了如上所述进行了表面处理的眼内透镜插入器具。该方法包括通过将至少具有羧基的水不溶性聚合物和多官能反应性化合物与有机溶剂混合来制备涂布溶液; 将该溶液施用在医疗器械的表面上; 进行交联; 并进行化学反应过程。使涂层成为亲水性。通过在插入管部的内表面上形成如上所述的涂层，进行交联，然后进行化学反应处理，使眼内透镜插入器具亲水。

8. 发明申请

US20100312255A1 METHOD OF PRODUCING MEDICAL INSTRUMENT 有权
标题翻译：生产医用仪器的方法
公开(公告)号：US20100312255A1
公开(公告)日：2010-12-09
申请号：US12864074
申请日：2008-12-17
申请人： Kohsuke Satake , Kazuharu Niwa , Ryo Matsushita , Yasuhiko Suzuki , Hiroko Nomura , Kazuhiko Nakada
发明人： Kohsuke Satake , Kazuharu Niwa , Ryo Matsushita , Yasuhiko Suzuki , Hiroko Nomura , Kazuhiko Nakada
IPC分类号： A61F9/007 , B05D3/10
CPC分类号： A61F2/1664 , A61F2/0077 , A61F2/1675 , A61L29/085 , A61L31/10 , C09D101/14 , C09D101/32
摘要： A method of producing a medical instrument whereby a highly hydrophilic and lubricant coating layer having a high durability can be formed by a simple technique and thus highly hydrophilic and lubricant properties can be imparted to a surface of a medical instrument. An intraocular lens insertion instrument having been subjected to a surface treatment as described above is also provided. The method comprises the steps of: preparing a coating solution by mixing at least a water-insoluble polymer having carboxyl group and a polyfunctional reactive compound with an organic solvent; applying this solution on the surface of the medical instrument; conducting crosslinking; and performing a chemical reaction process whereby the coating layer is made hydrophilic. The intraocular lens insertion instrument is made hydrophilic by forming the coating layer as described above on an inner surface of an insertion tube portion, crosslinking and then performing the chemical reaction process.
摘要翻译：通过简单的技术可以形成具有高耐久性的高亲水性和润滑性涂层的医疗器械的制造方法，能够赋予医疗器械表面更高的亲水性和润滑性。还提供了如上所述进行了表面处理的眼内透镜插入器具。该方法包括以下步骤：通过将至少具有羧基的水不溶性聚合物和多官能反应性化合物与有机溶剂混合来制备涂布溶液; 将该溶液施用在医疗器械的表面上; 进行交联; 并进行化学反应过程，由此使涂层成为亲水性。通过在插入管部的内表面上形成如上所述的涂层，进行交联，然后进行化学反应处理，使眼内透镜插入器具亲水。

9. 发明授权

US07037954B2 Ocular lens material 失效
标题翻译：眼镜材料
公开(公告)号：US07037954B2
公开(公告)日：2006-05-02
申请号：US10648489
申请日：2003-08-27
申请人： Masaki Baba , Tsuyoshi Watanabe , Kazuhiko Nakada
发明人： Masaki Baba , Tsuyoshi Watanabe , Kazuhiko Nakada
IPC分类号： C08F2/46 , C08F2/50
CPC分类号： A61L27/16 , A61L27/14 , A61L2430/16 , C08F230/08 , C08F283/12 , C08F290/068 , C08F290/148 , C08L51/085 , G02B1/043 , Y10S525/903 , Y10S525/906 , Y10S525/936 , C08L2666/04 , C08L2666/02
摘要： An ocular lens material comprising a copolymer prepared by polymerization with heating of a monomer mixture and/or with irradiating a monomer mixture with ultraviolet ray by means of a molding method, the monomer mixture containing a polysiloxane macromonomer A, a Si-containing alkyl methacrylate B, a hydrophilic monomer C comprising NVP as C-1 and another hydrophilic monomer C-2, another monomer D and a crosslinkable monomer E comprising a crosslinkable monomer E-1 containing at least one group selected from acryloyl group, vinyl group and allyl group, and methacryloyl group, and a crosslinkable monomer E-2 containing at least two methacryloyl groups as main components, wherein (A+B)/C (weight ratio) is 30/70 to 70/30, A/B is 25/75 to 75/25, C-1/C-2 is 50/50 to 100/0, the amount of D is 0 to 20% by weight in the monomer mixture, which has high oxygen permeability, high mechanical strength, excellent surface wettability and low surface frictional property.
摘要翻译：一种眼透镜材料，其包含通过单体混合物加热聚合制备的共聚物和/或通过模塑方法用紫外线照射单体混合物制备的共聚物，所述单体混合物含有聚硅氧烷大分子单体A，含Si的烷基甲基丙烯酸酯B 包含NVP作为C-1的亲水性单体C和另一种亲水性单体C-2，另一单体D和可交联单体E，其包含含有至少一个选自丙烯酰基，乙烯基和烯丙基的基团的可交联单体E-1，和甲基丙烯酰基，以及含有至少两个甲基丙烯酰基作为主要成分的交联性单体E-2，其中（A + B）/ C（重量比）为30/70〜70/30，A / B为25/75〜 75/25，C-1 / C-2为50/50〜100/0，D为0〜20重量％，单体混合物的透氧性高，机械强度高，表面润湿性优异，低表面摩擦性能。

10. 发明授权

US06638991B2 Material for ocular lens 有权
公开(公告)号：US06638991B2
公开(公告)日：2003-10-28
申请号：US09926560
申请日：2001-11-19
申请人： Masaki Baba , Tsuyoshi Watanabe , Kazuhiko Nakada
发明人： Masaki Baba , Tsuyoshi Watanabe , Kazuhiko Nakada
IPC分类号： C08F250
CPC分类号： A61L27/16 , A61L27/14 , A61L2430/16 , C08F230/08 , C08F283/12 , C08F290/068 , C08F290/148 , C08L51/085 , G02B1/043 , Y10S525/903 , Y10S525/906 , Y10S525/936 , C08L2666/04 , C08L2666/02
摘要： An ocular lens material comprising a copolymer prepared by polymerization with heating of a monomer mixture and/or with irradiating a monomer mixture with ultraviolet ray by means of a molding method, the monomer mixture containing a polysiloxane macromonomer A, a Si-containing alkyl methacrylate B, a hydrophilic monomer C comprising NVP as C-1 and another hydrophilic monomer C-2, another monomer D and a crosslinkable monomer E comprising a crosslinkable monomer E-1 containing at least one group selected from acryloyl group, vinyl group and allyl group, and methacryloyl group, and a crosslinkable monomer E-2 containing at least two methacryloyl groups as main components, wherein (A+B)/C (weight ratio) is 30/70 to 70/30, A/B is 25/75 to 75/25, C-1/C-2 is 50/50 to 100/0, the amount of D is 0 to 20% by weight in the monomer mixture, which has high oxygen permeability, high mechanical strength, excellent surface wettability and low surface frictional property.

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