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1. 发明授权

US08142771B2 Use of coccidian 有权
标题翻译：使用球虫
公开(公告)号：US08142771B2
公开(公告)日：2012-03-27
申请号：US12593851
申请日：2008-03-28
申请人： Xun Suo , Xiaojia Wang , Xianyong Liu , Tuanyuan Shi , Lili Hao , Wenchao Yan , Hongyan Wang , Jianan Li
发明人： Xun Suo , Xiaojia Wang , Xianyong Liu , Tuanyuan Shi , Lili Hao , Wenchao Yan , Hongyan Wang , Jianan Li
IPC分类号： C12N15/00 , A01N63/00 , A01N65/00 , A61K48/00
CPC分类号： A61K39/012 , A61K35/68 , A61K39/00 , A61K39/12 , A61K39/145 , A61K2039/522 , A61K2039/523 , A61K2039/542 , A61K2039/552 , C12N2760/16134 , Y02A50/489
摘要： The present invention provides a novel use of coccidian, specifically relates to the use of coccidian as a vaccine live vector. The present invention further provides a live vaccine with coccidian as a vector, which is transgenic coccidian capable of expressing exogenous protein or stably transfected coccidian that contain expression vector and can express exogenous coccidian. The present coccidian vector live vaccine can induce organisms to simultaneously generate protective humoral and cellular immune responses (including the mucosal immune response), as well as generate memory responses, which can be readily carried out and has stable effect and high biological safety without generating immune tolerance.
摘要翻译：本发明提供了球虫的新用途，具体涉及球虫作为疫苗活载体的用途。本发明还提供具有球虫作为载体的活疫苗，其是能够表达含有表达载体并能表达外源球虫的外源蛋白或稳定转染的球虫的转基因球虫。本发明的球虫载体活疫苗可以诱导生物体同时产生保护性体液和细胞免疫应答（包括粘膜免疫应答），并产生记忆反应，其可以容易地进行并且具有稳定的效果和高生物安全性而不产生免疫公差。

2. 发明申请

US20100183668A1 USE OF COCCIDIAN 有权
标题翻译：使用COCCIDIAN
公开(公告)号：US20100183668A1
公开(公告)日：2010-07-22
申请号：US12593851
申请日：2008-03-28
申请人： Xun Suo , Xiaojia Wang , Xianyong Liu , Tuanyuan Shi , Lili Hao , Wenchao Yan , Hongyan Wang , Jianan Li
发明人： Xun Suo , Xiaojia Wang , Xianyong Liu , Tuanyuan Shi , Lili Hao , Wenchao Yan , Hongyan Wang , Jianan Li
IPC分类号： A61K39/145 , A61K39/012 , A61P37/04
CPC分类号： A61K39/012 , A61K35/68 , A61K39/00 , A61K39/12 , A61K39/145 , A61K2039/522 , A61K2039/523 , A61K2039/542 , A61K2039/552 , C12N2760/16134 , Y02A50/489
摘要： The present invention provides a novel use of coccidian, specifically relates to the use of coccidian as a vaccine live vector. The present invention further provides a live vaccine with coccidian as a vector, which is transgenic coccidian capable of expressing exogenous protein or stably transfected coccidian that contain expression vector and can express exogenous coccidian. The present coccidian vector live vaccine can induce organisms to simultaneously generate protective humoral and cellular immune responses (including the mucosal immune response), as well as generate memory responses, which can be readily carried out and has stable effect and high biological safety without generating immune tolerance.
摘要翻译：本发明提供了球虫的新用途，具体涉及球虫作为疫苗活载体的用途。本发明还提供具有球虫作为载体的活疫苗，其是能够表达含有表达载体并能表达外源球虫的外源蛋白或稳定转染的球虫的转基因球虫。本发明的球虫载体活疫苗可以诱导生物体同时产生保护性体液和细胞免疫应答（包括粘膜免疫应答），并产生记忆反应，其可以容易地进行并且具有稳定的效果和高生物安全性而不产生免疫公差。

3. 发明授权

US08935054B2 Monitoring system for controlling liftable and steer axles on trucks or tractor trailers 有权
标题翻译：用于控制卡车或拖拉机拖车上的可升降和转向轴的监控系统
公开(公告)号：US08935054B2
公开(公告)日：2015-01-13
申请号：US13286282
申请日：2011-11-01
申请人： John Mantini , Michael Braithwaite , Hongyan Wang
发明人： John Mantini , Michael Braithwaite , Hongyan Wang
IPC分类号： B60R22/00 , E05F15/00 , G05D1/00 , G05D3/00 , G06F7/00 , B62D61/12 , B60G17/019 , B60G17/04 , G01P3/44 , B60W50/00
CPC分类号： B62D61/12 , B60G17/019 , B60G17/04 , B60G2300/02 , B60G2300/042 , B60G2400/10 , B60G2400/50 , B60G2400/70 , B60G2500/20 , B60G2500/22 , B60G2500/30 , B60W2050/0045 , B60Y2200/147 , G01P3/44
摘要： A monitoring system to control lift axles on a vehicle having a means for sensing vehicle speed and direction, a means for measuring the weight on the lift axles and fixed axles on the vehicle, and a control module for controlling one or more lift axles on the vehicle is provided. The control module comprises a receiver for receiving information from the sensing means and the measuring means, a processor, and output means for causing the lift axles to be lifted when the vehicle is moving in reverse. The processor causes or permits the lift axle to 1) lower when the vehicle moves forward for a programmable distance, 2) assume or maintain a lifted position when the vehicle is below a predetermined weight, 3) assume or maintain a lowered position when the vehicle carries over a predetermined weight, and 4) equalize weight between the lift axles and the fixed axles.
摘要翻译：一种用于控制具有用于感测车辆速度和方向的装置的车辆上的升降机轴的监视系统，用于测量车辆上的提升车轴和固定车轴上的重量的装置，以及用于控制车辆上的一个或多个提升轴的控制模块车辆被提供。控制模块包括一个接收器，用于从传感装置和测量装置接收信息，一个处理器和一个输出装置，用于当车辆反向移动时使提升轴被提升。当车辆向前移动一段可编程的距离时，处理器引起或允许提升轴1）下降; 2）当车辆低于预定重量时，假定或保持提升位置，3）当车辆处于或保持下降位置时，承载预定重量，以及4）使升降机轴和固定轴之间的重量相等。

4. 发明申请

US20080254454A1 GENETIC MARKERS FOR ASSESSING RISK OF PREMATURE BIRTH RESULTING FROM PRETERM PREMATURE RUPTURE OF MEMBRANES 有权
标题翻译：用于评估从预先破坏膜产生的预期出生风险的遗传标记
公开(公告)号：US20080254454A1
公开(公告)日：2008-10-16
申请号：US11734383
申请日：2007-04-12
申请人： Jerome F. Strauss , Hongyan Wang
发明人： Jerome F. Strauss , Hongyan Wang
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： A method to identify women who are at risk for preterm delivery due to premature rupture of membranes (PPROM) is provided. The method entails detecting the presence of SERPINH1 gene variants that express low levels of the gene product, heat shock protein Hsp47. The occurrence of a T (rather than C) at a single nucleotide polymorphism (SNP) site at position −656 of the SERPINH1 gene promoter, together with the absence of a 12 base pair deletion at positions −694 to −683 of the promoter, result in an increased risk of PPROM. The method enables medical professionals to identify those at risk, and to provide suitable therapeutic intervention.
摘要翻译：提供了一种识别由于膜过早破裂（PPROM）而处于早产的风险的妇女的方法。该方法需要检测表达低水平的基因产物，热休克蛋白Hsp47的SERPINH1基因变体的存在。在SERPINH1基因启动子的位置-656处的单核苷酸多态性（SNP）位点处的T（而不是C）的出现以及启动子位置-694至-683位置处不存在12个碱基对缺失，导致PPROM的风险增加。该方法使医疗专业人员能够识别处于危险中的人员，并提供适当的治疗干预。

5. 外观设计

USD972364S1 Lid 有权
公开(公告)号：USD972364S1
公开(公告)日：2022-12-13
申请号：US29792897
申请日：2022-04-29
申请人： Hongyan Wang
设计人： Hongyan Wang

6. 发明授权

US08862867B2 Method and system for protecting security of the third layer mobility user plane data in NGN 有权
标题翻译：用于保护NGN中第三层移动用户平面数据安全的方法和系统
公开(公告)号：US08862867B2
公开(公告)日：2014-10-14
申请号：US13257955
申请日：2010-03-22
申请人： Hongyan Wang , Yinxing Wei
发明人： Hongyan Wang , Yinxing Wei
IPC分类号： H04L29/06 , H04W12/06 , H04L9/00 , H04L9/08 , H04W12/04 , H04W80/04
CPC分类号： H04L63/08 , H04L63/06 , H04L63/164 , H04L2463/061 , H04W12/04 , H04W12/06 , H04W80/04
摘要： The disclosure discloses a method for protecting security of layer-3 mobility user plane data in Next Generation Network (NGN), includes: performing authentication by a terminal with an authentication server; after the authentication is passed, obtaining a shared key material by both the terminal and the authentication server; generating, by the terminal and the authentication server, a mobility data security key according to the shared key material; transmitting, by the authentication server, the generated mobility data security key to a mobility data transmission module; protecting security of the layer-3 mobility user plane data, by the terminal and the mobility data transmission module, by using the mobility data security key. The disclosure also discloses a system for protecting security of layer-3 mobility user plane data in NGN. By using the method and the system provided by the disclosure, the protection for security of user plane data between the NGN user and the NGN network side is realized, and the security of user plane data of the terminal in layer-3 mobility session is enhanced.
摘要翻译：本公开公开了一种用于保护下一代网络（NGN）中的第3层移动性用户平面数据的安全性的方法，包括：通过终端与认证服务器进行认证; 在认证通过之后，由终端和认证服务器获得共享密钥资料; 由所述终端和所述认证服务器根据所述共享密钥材料生成移动性数据安全密钥; 由所述认证服务器将生成的移动性数据安全密钥发送到移动性数据传输模块; 通过使用移动性数据安全密钥，由终端和移动性数据传输模块保护第3层移动性用户平面数据的安全性。本公开还公开了一种用于保护NGN中第3层移动用户平面数据的安全性的系统。通过使用本公开提供的方法和系统，实现了NGN用户与NGN网络侧用户平面数据安全保护，提高了第3层移动性会话终端用户平面数据的安全性。

7. 发明申请

US20130047220A1 Method and system for multi-access authentication in next generation network 有权
标题翻译：下一代网络多接入认证方法与系统
公开(公告)号：US20130047220A1
公开(公告)日：2013-02-21
申请号：US13641018
申请日：2010-11-18
申请人： Hongyan Wang , Yinxing Wei , Yifeng Bi
发明人： Hongyan Wang , Yinxing Wei , Yifeng Bi
IPC分类号： G06F21/00
CPC分类号： H04W12/06 , H04L9/0816 , H04L9/321 , H04L9/3271 , H04L63/06 , H04L63/061 , H04L63/0815 , H04W12/04
摘要： The disclosure provides a method for multi-access authentication in Next Generation Network (NGN), which includes: a network side authentication center generates an authentication vector after receiving user terminal information from a user terminal, wherein the user terminal information includes subscription information and multi-access information of the user terminal; the user terminal performs authentication on the network side after receiving an authentication request from the network side authentication center, and generates keying material and network side authentication information upon successful authentication, and sends the network side authentication information to the network side authentication center, wherein the authentication request includes authentication information; the network side authentication center performs authentication on the network side authentication information using the authentication vector, generates keying material according to the multi-access information of the user terminal upon successful authentication, and inform an access forwarding functional module of the keying material; the access forwarding functional module encrypts and decrypts access service information of the user terminal according to the keying material. The disclosure also provides a system of the method. The disclosure enhances the efficiency with which the user terminal accesses the network.
摘要翻译：本发明提供了一种下一代网络（NGN）中的多接入认证方法，包括：网络侧认证中心从用户终端收到用户终端信息后生成认证向量，其中用户终端信息包括订阅信息和多 - 用户终端的访问信息; 用户终端在接收到来自网络侧认证中心的认证请求后，在网络侧进行认证，成功认证后生成密钥资料和网络侧认证信息，并将网络侧认证信息发送给网络侧认证中心，其中，认证请求包括认证信息; 网络侧认证中心使用认证向量对网络侧认证信息进行认证，成功认证后根据用户终端的多路访问信息生成密钥资料，通知接入转发功能模块的密钥资料; 接入转发功能模块根据密钥资料加密和解密用户终端的接入业务信息。本公开还提供了该方法的系统。本公开增加了用户终端访问网络的效率。

8. 发明授权

US09102949B2 CNS targeting AAV vectors and methods of use thereof 有权
标题翻译：针对AAV载体的CNS及其使用方法
公开(公告)号：US09102949B2
公开(公告)日：2015-08-11
申请号：US13642719
申请日：2011-04-22
申请人： Guangping Gao , Hongwei Zhang , Hongyan Wang , Zuoshang Xu
发明人： Guangping Gao , Hongwei Zhang , Hongyan Wang , Zuoshang Xu
IPC分类号： C12N15/86 , C12N15/864 , C12N15/113 , A61K38/50 , A61K31/713 , C12N9/80 , C12N7/00 , A61K48/00 , C12N15/63
CPC分类号： C12N15/86 , A61K31/713 , A61K38/50 , A61K48/00 , A61K48/0058 , A61K48/0075 , C12N7/00 , C12N9/80 , C12N15/1137 , C12N15/635 , C12N15/8645 , C12N2310/141 , C12N2750/14133 , C12N2750/14141 , C12N2750/14143 , C12N2750/14145 , C12N2750/14162 , C12N2810/10 , C12N2840/007 , C12Y305/01015
摘要： The invention in some aspects relates to recombinant adeno-associated viruses useful for targeting transgenes to CNS tissue, and compositions comprising the same, and methods of use thereof. In some aspects, the invention provides methods and compositions for treating CNS-related disorders.
摘要翻译：本发明在一些方面涉及可用于靶向转基因到CNS组织的重组腺相关病毒，以及包含其的组合物及其使用方法。在一些方面，本发明提供了用于治疗CNS相关疾病的方法和组合物。

9. 发明申请

US20120265982A1 METHOD, AUTHENTICATION SERVER, TERMINAL AND SYSTEM FOR IMPLEMENTING KEY MAPPING 审中-公开
标题翻译：方法，认证服务器，终端和执行关键映射的系统
公开(公告)号：US20120265982A1
公开(公告)日：2012-10-18
申请号：US13257950
申请日：2010-03-23
申请人： Hongyan Wang , Yinxing Wei
发明人： Hongyan Wang , Yinxing Wei
IPC分类号： H04L9/32
CPC分类号： H04W12/06 , H04W12/04 , H04W36/0038
摘要： The disclosure discloses a method for implementing key mapping applied to a Next Generation Network (NGN), which mainly includes: when a handoff of a terminal from an original network to a destination network is performed, an authentication server receiving a key material mapping request from the terminal, mapping an original key material in the original network to obtain a destination key material in the destination network, and setting up communication security between the terminal and the destination network. In addition, the disclosure further discloses an authentication server, a terminal and a system for implementing key mapping. By applying the solution of the disclosure, when the handoff of the terminal between different NGNs is performed, it is possible to improve the efficiency of session key generation and to reduce the time delay of the handoff of the terminal between the networks, and it is advantageous to reduce authentication signaling interaction and the load of the authentication server.
摘要翻译：本公开公开了一种用于实现应用于下一代网络（NGN）的密钥映射的方法，其主要包括：当终端从原始网络切换到目的地网络时，认证服务器接收密钥材料映射请求，终端，将原始网络中的原始密钥材料映射到目的地网络中的目的地密钥材料，并且在终端和目的网络之间建立通信安全性。此外，本公开还公开了一种认证服务器，终端和用于实现密钥映射的系统。通过应用本公开的解决方案，当执行不同NGN之间的终端切换时，可以提高会话密钥生成的效率并减少终端在网络之间切换的时间延迟，并且它是有利于减少认证信令交互和认证服务器的负载。

10. 发明申请

US20120123646A1 Monitoring System for Controlling Liftable and Steer Axles on Trucks or Tractor Trailers 有权
标题翻译：用于控制卡车或拖拉机拖车上的可升降转向轴的监控系统
公开(公告)号：US20120123646A1
公开(公告)日：2012-05-17
申请号：US13286282
申请日：2011-11-01
申请人： John Mantini , Michael Braithwaite , Hongyan Wang
发明人： John Mantini , Michael Braithwaite , Hongyan Wang
IPC分类号： B60W30/00 , G01P15/00 , B60W10/22 , G06F19/00 , B60W10/20
CPC分类号： B62D61/12 , B60G17/019 , B60G17/04 , B60G2300/02 , B60G2300/042 , B60G2400/10 , B60G2400/50 , B60G2400/70 , B60G2500/20 , B60G2500/22 , B60G2500/30 , B60W2050/0045 , B60Y2200/147 , G01P3/44
摘要： This invention provides a monitoring system to control liftable or steer axles on a truck or tractor-trailer by monitoring one or more input data types selected from the group consisting of speed and direction data, load data, turn signal data, engine data and emergency signal data. After processing the input data, a control module may control the lift axle electrical valving to lift one or more liftable axles, and may also lock the steerable axle in a straight position at a predetermined forward speed or adjust the pressure on the air suspension of a steer axle to equalize axle bearing weight.
摘要翻译：本发明提供一种监视系统，用于通过监视从由速度和方向数据，负载数据，转向信号数据，发动机数据和紧急信号组成的组中选择的一个或多个输入数据类型来控制卡车或拖拉机拖车上的可升降或转向轴数据。在处理输入数据之后，控制模块可以控制提升轴电气阀来提升一个或多个可升降的轴，并且还可以以预定的前进速度将可转向的轴锁定在直线位置，或者调节空气悬架上的压力转向轴以平衡车轴承重量。

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