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1. 发明申请

US20060141450A1 Magnetism based rapid cell separation 有权
标题翻译：基于磁性的快速细胞分离
公开(公告)号：US20060141450A1
公开(公告)日：2006-06-29
申请号：US10538498
申请日：2002-12-31
申请人： Xu Zhang , Xin Xie , Depu Chen , Weiyang Fei , Jing Cheng
发明人： Xu Zhang , Xin Xie , Depu Chen , Weiyang Fei , Jing Cheng
IPC分类号： C12Q1/70 , G01N33/567 , C12N1/20
CPC分类号： G01N33/54333 , C12N1/02 , C12N7/00 , C12N2760/16051 , C12N2795/14151 , C12Q1/24 , G01N33/54326
摘要： This invention relates generally to the field of. In particular, the invention provides processes and kits for isolating a target cell, cellular organelle or virus from a sample, using inter alia, non- or low-specific binding between a target cell, cellular organelle or virus with a magnetic microbead.
摘要翻译：本发明一般涉及领域。特别地，本发明提供了用于使用靶细胞，细胞器官细胞或病毒与磁性微珠之间的非特异性或低特异性结合从样品中分离靶细胞，细胞器官细胞或病毒的方法和试剂盒。

2. 发明授权

US07776580B2 Magnetism based rapid cell separation 有权
标题翻译：基于磁性的快速细胞分离
公开(公告)号：US07776580B2
公开(公告)日：2010-08-17
申请号：US10538498
申请日：2002-12-31
申请人： Xu Zhang , Xin Xie , Depu Chen , Weiyang Fei , Jing Cheng
发明人： Xu Zhang , Xin Xie , Depu Chen , Weiyang Fei , Jing Cheng
IPC分类号： C12N7/02 , C12N5/00 , C12N1/02 , C12P19/34 , G01N33/50
CPC分类号： G01N33/54333 , C12N1/02 , C12N7/00 , C12N2760/16051 , C12N2795/14151 , C12Q1/24 , G01N33/54326
摘要： This invention relates generally to the field of cell seperation. In particular, the invention provides processes for isolating a target cell, cellular organelle or virus from a sample, using inter alia, nonspecific binding between a target cell, cellular organelle or virus with a magnetic microbead modified to comprise hydroxyl, carboxyl or epoxy groups.
摘要翻译：本发明一般涉及细胞分离领域。特别地，本发明提供了从样品中分离靶细胞，细胞器官细胞或病毒的方法，尤其是靶细胞，细胞器或病毒与修饰成包含羟基，羧基或环氧基团的磁性微珠之间非特异性结合。

3. 发明申请

US20060166190A1 Magnetism based nucleic acid amplification 审中-公开
标题翻译：基于磁性的核酸扩增
公开(公告)号：US20060166190A1
公开(公告)日：2006-07-27
申请号：US10538443
申请日：2002-12-31
申请人： Xin Xie , Xu Zhang , Depu Chen , Weiyang Fei , Jing Chen
发明人： Xin Xie , Xu Zhang , Depu Chen , Weiyang Fei , Jing Chen
IPC分类号： C12Q1/70 , C12Q1/68
CPC分类号： C12Q1/6806 , C12Q1/6844 , C12Q2563/149 , C12Q2563/137 , C12Q2563/131 , C12Q2563/143
摘要： This invention relates generally to the field of nucleic acid amplification. In particular, the invention provides processes and kits for amplifying a nucleic acid of a target cell or virus using, using inter alia, binding between a target cell, cellular organelle or virus with a magnetic microbead.
摘要翻译：本发明一般涉及核酸扩增领域。特别地，本发明提供使用特别是使用靶细胞，细胞器官细胞或病毒与磁性微珠结合来扩增靶细胞或病毒的核酸的方法和试剂盒。

4. 发明申请

US20050009002A1 Processes for producing coated magnetic microparticles and uses thereof 审中-公开
标题翻译：制备涂覆磁性微粒的方法及其应用
公开(公告)号：US20050009002A1
公开(公告)日：2005-01-13
申请号：US10472663
申请日：2002-03-20
申请人： Depu Chen , Xin Xie , Xu Zhang , Baoquan Sun
发明人： Depu Chen , Xin Xie , Xu Zhang , Baoquan Sun
IPC分类号： B01J2/00 , B01J13/12 , B01J13/14 , B03C1/02 , G01N33/543 , G01N33/553 , C12Q1/00
CPC分类号： G01N33/54326 , B01J2/006 , B01J13/12 , B01J2219/005 , B01J2219/00648 , B01J2219/00655
摘要： This invention relates generally to the field of production of coated magnetizable microparticles and uses thereof. In particular, the invention provides a process for producing coated magnetizable microparticles with active functional groups, which process uses, inter alia, conducting polymerization of said coating monomers on the surface of magnetic particle to form coated magnetizable microparticles with active functional groups in the presence of a coupling agent, coating monomers, a functionalization reagent, a cross-linking agent and an initiator in an organic solvent containing a surfactant. The coated magnetizable microparticles produced according to the present processes and uses of the coated magnetizable microparticles, e.g., in isolating and/or manipulating various moieties are also provided.
摘要翻译：本发明一般涉及可涂覆的可磁化微粒的生产领域及其用途。特别地，本发明提供了一种制备具有活性官能团的包覆的可磁化微粒的方法，该方法尤其用于在磁性颗粒的表面上进行所述涂覆单体的聚合，以形成具有活性官能团的可涂覆的可磁化微粒，偶联剂，包衣单体，官能化试剂，交联剂和引发剂在含有表面活性剂的有机溶剂中。还提供根据本发明方法制备的包覆的可磁化微粒和涂覆的可磁化微粒的用途，例如分离和/或操纵各种部分。

5. 发明申请

US20110167041A1 METHOD AND DEVICE FOR MAINTAINING A CHANGELOG IN DATA SYNCHRONIZATION 审中-公开
标题翻译：用于维护数据同步中的更改的方法和设备
公开(公告)号：US20110167041A1
公开(公告)日：2011-07-07
申请号：US13062941
申请日：2008-12-30
申请人： Liqin Fu , Tao Zhou , Jingchun Pu , Fei Ju , Xin Xie , Lei Yuan
发明人： Liqin Fu , Tao Zhou , Jingchun Pu , Fei Ju , Xin Xie , Lei Yuan
IPC分类号： G06F17/30
CPC分类号： H04L41/00 , G06F16/27 , H04L67/1095
摘要： A method and device for maintaining a changelog in data synchronization are provided in the present invention, in which the changelog is configured to record an operation executed for an object and is composed of data record items. The data record item includes flag information configured to uniquely identify an object and an operation type corresponding to the flag information, the operation type includes adding, updating and deleting. The method includes: reading, between two times of the data synchronization, flag information of a first data record item which is required to be added to the changelog; searching for whether there is a second data record item including the flag information in the changelog, and in a situation that there is the second data record item, setting the second data record item according to the first data record item. By the present invention, the changelog file can be prevented from continuously increasing.
摘要翻译：在本发明中提供了一种用于维持数据同步中的变更日志的方法和装置，其中更改日志被配置为记录对象执行的操作，并且由数据记录项组成。数据记录项目包括被配置为唯一地标识对象的标志信息和与标志信息相对应的操作类型，操作类型包括添加，更新和删除。该方法包括：在两次数据同步之间读取需要添加到更改日志的第一数据记录项的标志信息; 搜索包括更改日志中的标志信息的第二数据记录项目，以及在存在第二数据记录项目的情况下，根据第一数据记录项目设置第二数据记录项目。通过本发明，可以防止变更日志文件不断增加。

6. 发明授权

US09216962B2 Thiazole compounds, methods for preparation and use thereof 有权
标题翻译：噻唑化合物，其制备方法和用途
公开(公告)号：US09216962B2
公开(公告)日：2015-12-22
申请号：US14116944
申请日：2012-05-07
申请人： Fajun Nan , Fei Chen , Yangming Zhang , Jia Li , Yubo Zhou , Mingbo Su , Jian Ding , Linghua Meng , Xin Xie , Shixian Wang
发明人： Fajun Nan , Fei Chen , Yangming Zhang , Jia Li , Yubo Zhou , Mingbo Su , Jian Ding , Linghua Meng , Xin Xie , Shixian Wang
IPC分类号： C07D417/00 , C07D277/56 , C07D277/58 , C07D277/60 , C07D417/14 , C07D417/04
CPC分类号： C07D277/56 , C07D277/58 , C07D277/60 , C07D417/04 , C07D417/14
摘要： The present invention relates to thiazole compounds of formula I, the method for preparation and use thereof. More specifically, the present invention relates to novel derivatives of natural product largazole, the method for preparing them and their uses for treatments against tumor and multiple sclerosis as inhibitors of histone deacetylase.
摘要翻译：本发明涉及式I的噻唑化合物，其制备方法和用途。更具体地，本发明涉及天然产物大唑的新衍生物，其制备方法及其用于治疗肿瘤和多发性硬化的用途，作为组蛋白脱乙酰酶的抑制剂。

7. 发明申请

US20120296870A1 Method for Finding, Updating and Synchronizing Modified Record Item and Data Synchronizing Device 审中-公开
标题翻译：查找，更新和同步修改记录项和数据同步设备的方法
公开(公告)号：US20120296870A1
公开(公告)日：2012-11-22
申请号：US13519195
申请日：2010-04-23
申请人： Liqin Fu , Jingchun Pu , Fei Ju , Xin Xie , Shangkai Wei , Jianqiao He
发明人： Liqin Fu , Jingchun Pu , Fei Ju , Xin Xie , Shangkai Wei , Jianqiao He
IPC分类号： G06F17/30
CPC分类号： H04L67/1095 , G06F16/2358 , G06F16/27
摘要： The present invention provides a method for searching a change log item, which includes: in a change log of a data synchronizing device, ordering change log items according to numerical values of entity identifiers contained in the items; in the data synchronizing device, when data updating occurs in an entity in a database of the data synchronizing device, using a search algorithm of elements in an ordered sequence to search out whether a change log item containing an entity identifier of the entity exists in the change log. The present invention also provides a data synchronizing device.
摘要翻译：本发明提供了一种搜索变更日志项目的方法，包括：在数据同步装置的变更日志中，根据项目中包含的实体标识符的数值对排序变更日志项进行排序; 在数据同步装置中，当在数据同步装置的数据库中的实体中发生数据更新时，使用有序序列中的元素的搜索算法来搜索包含实体的实体标识符的改变日志项目是否存在于更改日志。本发明还提供一种数据同步装置。

8. 发明申请

US20120101988A1 Method for Managing Application Information Implemented by a Mobile Phone and Application Manager 审中-公开
标题翻译：管理移动电话和应用程序管理器实现的应用程序信息的方法
公开(公告)号：US20120101988A1
公开(公告)日：2012-04-26
申请号：US13380868
申请日：2010-05-10
申请人： Dingyong Gou , Gang Liu , Ping He , Xin Xie
发明人： Dingyong Gou , Gang Liu , Ping He , Xin Xie
IPC分类号： G06F7/00
CPC分类号： H04L67/2847 , H04L67/04 , H04W4/50 , H04W4/60
摘要： The present invention discloses a method for implementing management of application information in a mobile phone and an application manager, wherein, the method includes: after the mobile phone is powered on, its application manager reading application information from a file system and caching the application information in background. In the present invention, when the user starts up the application manager, the cached application information can be directly read and displayed, and does not need to be loaded from the file system, thus greatly improving the speed of displaying the application information, and thereby greatly enhancing the user's experience. In addition, when the user updates the application and inserts a memory card into the mobile phone, the information is synchronously updated in background by the application manager to be provided to the user for obtaining and displaying at any time.
摘要翻译：本发明公开了一种用于实现移动电话和应用管理器中的应用信息管理的方法，其特征在于，该方法包括：在手机上电之后，其应用管理器从文件系统读取应用信息并缓存应用信息在背景中。在本发明中，当用户启动应用管理器时，缓存的应用信息可以被直接读取和显示，并且不需要从文件系统加载，从而大大提高显示应用信息的速度，从而大大提升用户体验。此外，当用户更新应用程序并将存储卡插入到移动电话中时，该信息由应用程序管理器在后台被同步地更新以提供给用户以便随时获取和显示。

9. 发明申请

US20100168183A1 SUBSITUTED CYCLIC COMPOUND, ITS PREPARATION PROCESS AND ITS MEDICAL USE 失效
标题翻译：替代周期化合物，其制备方法及其医疗用途
公开(公告)号：US20100168183A1
公开(公告)日：2010-07-01
申请号：US11993440
申请日：2006-06-21
申请人： Mingwei Wang , Na Li , Xin Xie , Qing Liu , Caihong Zhou , Fajun Nan
发明人： Mingwei Wang , Na Li , Xin Xie , Qing Liu , Caihong Zhou , Fajun Nan
IPC分类号： A61K31/381 , C07D409/12 , A61K31/4439 , A61P3/04 , A61P5/50 , A61P3/10
CPC分类号： C07D333/38
摘要： The present invention provides a substituted cyclic compound of the following general formula I or II: its preparation process and its use as a glucagon-like peptide-1 receptor regulator for preventing or treating metabolic disorders including, but not limited to, diabetes, insulin resistance and obesity, etc.
摘要翻译：本发明提供以下通式I或II的取代的环状化合物：其制备方法及其作为胰高血糖素样肽-1受体调节剂用于预防或治疗代谢紊乱的用途，包括但不限于糖尿病，胰岛素抵抗肥胖等

10. 发明授权

US09041481B2 Artificial microstructure and artificial electromagnetic material using the same 有权
标题翻译：使用人造微结构和人造电磁材料
公开(公告)号：US09041481B2
公开(公告)日：2015-05-26
申请号：US13583908
申请日：2011-10-27
申请人： Ruopeng Liu , Jinjin Wang , Zhiya Zhao , Lin Luan , Chaofeng Kou , Xin Xie , Guo Zhong , Jincai Ye
发明人： Ruopeng Liu , Jinjin Wang , Zhiya Zhao , Lin Luan , Chaofeng Kou , Xin Xie , Guo Zhong , Jincai Ye
IPC分类号： H04B3/40 , B81B7/00 , H01Q15/00
CPC分类号： B81B7/00 , H01Q15/0086 , Y10T428/249921 , Y10T428/249922
摘要： The present invention provides an artificial microstructure employed in an artificial electromagnetic material. The artificial microstructure includes a first segment, a second segment, and a third segment. The first segment is parallel to the second segment, and the third segment is connected between the first segment and the second segment. The artificial electromagnetic material has a special electromagnetic effect. The artificial electromagnetic material can be applied to various electromagnetic application systems instead of the typical electromagnetic material.
摘要翻译：本发明提供在人造电磁材料中使用的人造微结构。人造微结构包括第一段，第二段和第三段。第一段与第二段平行，第三段连接在第一段和第二段之间。人造电磁材料具有特殊的电磁效应。人造电磁材料可以应用于各种电磁应用系统，而不是典型的电磁材料。

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