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1. 发明申请

US20160175291A1 SUPRESSION OF IGE PRODUCTION BY COMPOUNDS DERIVED FROM TRADITIONAL CHINESE MEDICINE 审中-公开
标题翻译：由传统中医药衍生的化合物制备骨骼肌生产
公开(公告)号：US20160175291A1
公开(公告)日：2016-06-23
申请号：US14857772
申请日：2015-09-17
申请人： Xiu-Min Li , Nan Yang , Chaoyi Mao , Ying Song
发明人： Xiu-Min Li , Nan Yang , Chaoyi Mao , Ying Song
IPC分类号： A61K31/4375 , A61K31/122 , A61K31/366
CPC分类号： A61K31/122 , A61K31/12 , A61K31/35 , A61K31/366 , A61K31/4745 , A61K31/475
摘要： The present invention relates to compounds and formulations derived from traditional Chinese medicine for use for the treatment and/or mediation of food allergies, in particular peanut allergies in humans by altering the activity and/or production of IgE.
摘要翻译：本发明涉及通过改变IgE的活性和/或产生来用于治疗和/或调解食物过敏症，特别是人体花生过敏的中药的化合物和制剂。

2. 发明授权

US10406191B2 Compounds, extracts and methods from chinese medicinal herb sophora flavescens that inhibit airway contraction 有权
公开(公告)号：US10406191B2
公开(公告)日：2019-09-10
申请号：US14762416
申请日：2014-01-21
申请人： Xiu-Min Li , Hugh A. Sampson , Nan Yang , Kamal Srivastava , Charles Emala
发明人： Xiu-Min Li , Hugh A. Sampson , Nan Yang , Kamal Srivastava , Charles Emala
IPC分类号： A61K36/489 , A61K31/4375 , A61K31/7048 , A61K31/352 , A61K31/439
摘要： The present invention relates to extracts of Sophora Flavescens, and compounds isolated therefrom for use in modulating airway smooth muscle contractility. Methods of creating enriched extracts of Sophora Flavescens are disclosed, as are specific compounds isolated therefrom. Methods for the treatment of disorders involving airway smooth muscle, such as asthma, using the compounds and extracts described herein are also disclosed.

3. 发明申请

US20150359834A1 COMPOUNDS, EXTRACTS AND METHODS FROM CHINESE MEDICINAL HERB SOPHORA FLAVESCENS THAT INHIBIT AIRWAY CONTRACTION 审中-公开
标题翻译：中国医药卫生组织的化合物，提取物和方法禁止航空承包
公开(公告)号：US20150359834A1
公开(公告)日：2015-12-17
申请号：US14762416
申请日：2014-01-21
申请人： Xiu-Min LI , Sampson HUGH , Nan YANG , Kamal SRIVASTAVA , Charles EMALA
发明人： Xiu-Min Li , Sampson Hugh , Nan Yang , Kamal Srivastava , Charles Emala
IPC分类号： A61K36/489 , A61K31/4375 , A61K31/439 , A61K31/352 , A61K31/7048
CPC分类号： A61K36/489 , A61K31/352 , A61K31/4375 , A61K31/439 , A61K31/7048
摘要： The present invention relates to extracts of Sophora Flavascens, and compounds isolated therefrom for use in modulating airway smooth muscle contractility. Methods of creating enriched extracts of Sophora Flavascens are disclosed, as are specific compounds isolated therefrom. Methods for the treatment of disorders involving airway smooth muscle, such as asthma, using the compounds and extracts described herein are also disclosed.
摘要翻译：本发明涉及苦参皂甙提取物及其分离的化合物，用于调节气道平滑肌收缩力。公开了生产Sophora Flavascens的富集提取物的方法，以及从其分离的特定化合物。还公开了使用本文所述的化合物和提取物治疗涉及气道平滑肌（例如哮喘）的病症的方法。

4. 发明授权

US10028985B2 Weight loss formulations, methods, and compositions based on traditional Chinese medicine 有权
公开(公告)号：US10028985B2
公开(公告)日：2018-07-24
申请号：US15101182
申请日：2014-12-03
申请人： Xiu-Min Li , Danna Chung , Nan Yang
发明人： Xiu-Min Li , Danna Chung , Nan Yang
IPC分类号： A61K36/00 , A61K36/074 , A61K36/752 , A61K36/481 , A61K36/62 , A61K36/718 , A61K36/732
摘要： The present invention relates to formulations made up from extracts from Ganoderma lucidum, rhizome of Coptis chinensis, Radix astragali, Nelumbo nucifera Gaertn, Chaenomeles speciosa, and Fructus Aurantii. Pursuant to the invention, the formulations are used to treat obesity and the biological sequelae of obesity including cholesterol levels and glucose levels. While not limited to any particular mechanism of action the formulations may assert their effects by altering gene expression, in particular, the expression of PPARγ, FABP4, CPT1, UCP2, and AMPK.

5. 发明授权

US10500169B2 Supression of IgE production by compounds derived from traditional chinese medicine 有权
公开(公告)号：US10500169B2
公开(公告)日：2019-12-10
申请号：US14857772
申请日：2015-09-17
申请人： Xiu-Min Li , Sean N. Parker Foundation
发明人： Xiu-Min Li , Nan Yang , Chaoyi Mao , Ying Song , Sean N. Parker
IPC分类号： A61K31/44 , A61K31/35 , A61K31/12 , A61K31/122 , A61K31/366 , A61K31/475 , A61K31/4745
CPC分类号： A61K31/122 , A61K31/12 , A61K31/35 , A61K31/366 , A61K31/475 , A61K31/4745
摘要： The present invention relates to compounds and formulations derived from traditional Chinese medicine for use for the treatment and/or mediation of food allergies, in particular peanut allergies in humans by altering the activity and/or production of IgE.

6. 发明授权

US08784065B2 Friction welding of titanium aluminide turbine to titanium alloy shaft 有权
标题翻译：钛铝合金涡轮对钛合金轴的摩擦焊接
公开(公告)号：US08784065B2
公开(公告)日：2014-07-22
申请号：US13114177
申请日：2011-05-24
申请人： Nan Yang , Jeff A. Jensen , Jesus G. Chapa Cabrera
发明人： Nan Yang , Jeff A. Jensen , Jesus G. Chapa Cabrera
IPC分类号： F01D5/02
CPC分类号： F01D5/025 , B23K20/129 , B23K20/233 , B23K2103/24 , F05D2220/40 , F05D2230/239 , F05D2230/25 , F05D2300/174 , F05D2300/182
摘要： A frictional welding process for joining a titanium aluminide turbine to a titanium alloy shaft is disclosed. The disclosed process includes preheating the turbine to a designated temperature, providing a specially-designed joining interface geometry at the distal end of the shaft and optimizing the frictional welding parameters. The frictional welding is carried out in multiple steps but, while the shaft is being spun by a rotating chuck, two different pressures and two different time periods are used until the narrower portions of the distal end of the shaft have been fused onto the welding surface of the turbine. Then, an additional forging step with yet another engagement pressure between the shaft and the turbine is carried out without rotation of the shaft.
摘要翻译：公开了一种用于将钛铝合金涡轮机连接到钛合金轴的摩擦焊接方法。所公开的方法包括将涡轮预热到指定温度，在轴的远端提供特别设计的接合界面几何形状并优化摩擦焊接参数。摩擦焊接是以多个步骤进行的，但是当轴通过旋转卡盘旋转时，使用两个不同的压力和两个不同的时间段，直到轴的远端的较窄部分已熔合到焊接表面上的涡轮。然后，在轴和涡轮之间的另一个接合压力下进行另外的锻造步骤而不转动轴。

7. 发明授权

US08118556B2 Compressor wheel for a turbocharger system 有权
标题翻译：用于涡轮增压器系统的压缩机轮
公开(公告)号：US08118556B2
公开(公告)日：2012-02-21
申请号：US12011684
申请日：2008-01-29
申请人： Nan Yang , Jeff A. Jensen
发明人： Nan Yang , Jeff A. Jensen
IPC分类号： F01D5/14
CPC分类号： F04D29/284 , B22C7/02 , B22D18/02 , B22D25/06 , F01D5/04 , F04D29/023 , F05D2220/40 , F05D2230/21 , F05D2300/15 , F05D2300/173 , F05D2300/6032 , Y10T29/49243 , Y10T29/49325
摘要： A turbocharger system for an internal combustion engine includes at least one compressor wheel. The at least one compressor wheel of a single stage or multiple stage turbocharger system is formed, such as by pressure casting, from at least one of an aluminum metal matrix composite and an aluminum alloy containing up to 5 weight percent scandium.
摘要翻译：用于内燃机的涡轮增压器系统包括至少一个压缩机叶轮。单级或多级涡轮增压器系统的至少一个压缩机叶轮，例如通过压铸，从至少一种铝金属基质复合材料和含有至多5重量％钪的铝合金形成。

8. 发明申请

US20080000558A1 Friction welding 审中-公开
标题翻译：摩擦焊接
公开(公告)号：US20080000558A1
公开(公告)日：2008-01-03
申请号：US11479599
申请日：2006-06-30
申请人： Nan Yang , Jesus G. Chapa-Cabrera
发明人： Nan Yang , Jesus G. Chapa-Cabrera
IPC分类号： C22F1/18
CPC分类号： C22F1/183
摘要： A method of bonding two materials by friction welding method. A first material may be made from a titanium aluminide intermetallic alloy and a second material may be made from a titanium alloy. The first material may be heated to a temperature between about 300° C. and about 800° C. The second material may be rotated relative to the first material. The first material and the second material may be pressed against each other while one of the first material, and the second material is rotated. The rotation of one of the first material and the second material may be stopped, and the first material and the second material may be pressed against each other after the rotation of one of the first material and the second material is stopped.
摘要翻译：一种通过摩擦焊接法将两种材料接合的方法。第一材料可以由钛铝化物金属间合金制成，第二材料可以由钛合金制成。可以将第一材料加热至约300℃至约800℃的温度。第二材料可以相对于第一材料旋转。第一材料和第二材料可以在第一材料和第二材料中的一个旋转的同时彼此挤压。可以停止第一材料和第二材料之一的旋转，并且在第一材料和第二材料之一的旋转停止之后第一材料和第二材料可以彼此挤压。

9. 发明授权

US08915708B2 Turbocharger with air buffer seal 有权
标题翻译：涡轮增压器带空气缓冲器密封
公开(公告)号：US08915708B2
公开(公告)日：2014-12-23
申请号：US13168178
申请日：2011-06-24
申请人： Nan Yang , Jeff A. Jensen , Robert C. Griffith
发明人： Nan Yang , Jeff A. Jensen , Robert C. Griffith
IPC分类号： F01D25/16 , F01D25/18 , F16C33/76 , F16J15/40 , F16C19/18
CPC分类号： F01D25/186 , F04D29/104 , F05D2220/40 , F16C19/184 , F16C33/762 , F16C2360/24 , F16J15/40
摘要： A turbocharger includes a turbine section, a compressor section and a bearing section. A turbine wheel and a compressor wheel are mounted on a shaft and the shaft is rotatably mounted in a bore of a housing. A lubrication system circulates lubricant through the bearing section. First and second spaced apart seals are positioned along the shaft. A recess is positioned between the first seal and the second seal to define an air buffer chamber. The air buffer chamber is provided with pressurized air to discourage lubricant leakage past the first seal.
摘要翻译：涡轮增压器包括涡轮部分，压缩机部分和轴承部分。涡轮机叶轮和压缩机叶轮安装在轴上，并且轴可旋转地安装在壳体的孔中。润滑系统通过轴承部分循环润滑剂。第一和第二间隔开的密封件沿着轴定位。凹部位于第一密封件和第二密封件之间以限定空气缓冲室。空气缓冲室设有加压空气以阻止经过第一密封的润滑剂泄漏。

10. 发明申请

US20130247019A1 Specifying Memory Resource Implementations for Deployment of a Graphical Program to Programmable Hardware 审中-公开
标题翻译：指定用于部署图形程序到可编程硬件的内存资源实现
公开(公告)号：US20130247019A1
公开(公告)日：2013-09-19
申请号：US13424149
申请日：2012-03-19
申请人： Lan Xu , Tianming Liang , Lei Song , Newton G. Petersen , Dustyn Blasig , Julian G. Valdez , Nan Yang , Hojin Kee
发明人： Lan Xu , Tianming Liang , Lei Song , Newton G. Petersen , Dustyn Blasig , Julian G. Valdez , Nan Yang , Hojin Kee
IPC分类号： G06F9/44
CPC分类号： G06F17/5054
摘要： System and method for managing and specifying hardware implementation of a graphical program. A graphical program that implements an algorithm is stored in a memory of a computer system. The graphical program meets one or more first specified implementation requirements and is targeted for deployment to a programmable hardware element. A plurality of sets of descriptive directives are also stored in the memory, where the descriptive directives are associated with the graphical program and specify one or more additional specified implementation requirements, e.g., memory resource implementations, optimization directives, and so forth, where the additional directives result from programmatic and/or user-specification. Each set of descriptive directives is useable by a synthesis tool to generate a respective hardware configuration program for deployment to the graphical programmable hardware element.
摘要翻译：用于管理和指定图形程序的硬件实现的系统和方法。实现算法的图形程序存储在计算机系统的存储器中。图形程序满足一个或多个第一指定的实现要求，并且被部署到可编程硬件元件。多个描述性指令集也存储在存储器中，其中描述性指令与图形程序相关联并且指定一个或多个附加的指定实现要求，例如存储器资源实现，优化指令等，其中额外的指令源于程序化和/或用户规范。每个描述性指令集合可由综合工具使用，以生成用于部署到图形可编程硬件元件的相应硬件配置程序。

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