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1. 发明授权

US08986933B2 Selective detection of human rhinovirus 有权
标题翻译：人类鼻病毒的选择性检测
公开(公告)号：US08986933B2
公开(公告)日：2015-03-24
申请号：US12315758
申请日：2008-12-05
申请人： Xiaoyan Lu , Dean Erdman
发明人： Xiaoyan Lu , Dean Erdman
IPC分类号： C12Q1/68 , C12P19/34 , C07H1/00 , C07H5/04 , C07H19/00 , C07H21/02 , C07H21/04 , C12Q1/70
CPC分类号： C12Q1/701 , C12Q2600/158
摘要： A process for detecting human rhinovirus nucleic acid in a biological sample, includes producing an amplification product by amplifying an human bocavirus nucleotide sequence using a forward primer of SEQ ID NO: 1, and a reverse primer of SEQ ID NO: 2, and measuring said amplification product to detect human rhinovirus in said biological sample. Also provided are reagents and methods for detecting and distinguishing human rhinovirus from other viruses. A kit is provided for detecting and quantifying human rhinovirus in a biological sample.
摘要翻译：用于在生物样品中检测人类鼻病毒核酸的方法包括使用SEQ ID NO：1的正向引物和SEQ ID NO：2的反向引物扩增人bocavirus核苷酸序列产生扩增产物，并测量所述扩增产物以检测所述生物样品中的人类鼻病毒。还提供了用于检测和区分人类鼻病毒与其他病毒的试剂和方法。提供了用于检测和定量生物样品中的人类鼻病毒的试剂盒。

2. 发明申请

US20100143881A1 Selective detection of human rhinovirus 有权
标题翻译：人类鼻病毒的选择性检测
公开(公告)号：US20100143881A1
公开(公告)日：2010-06-10
申请号：US12315758
申请日：2008-12-05
申请人： Xiaoyan Lu , Dean Erdman
发明人： Xiaoyan Lu , Dean Erdman
IPC分类号： C12Q1/70 , C07H21/04
CPC分类号： C12Q1/701 , C12Q2600/158
摘要： A process for detecting human rhinovirus nucleic acid in a biological sample, includes producing an amplification product by amplifying an human bocavirus nucleotide sequence using a forward primer of SEQ ID NO: 1, and a reverse primer of SEQ ID NO: 2, and measuring said amplification product to detect human rhinovirus in said biological sample. Also provided are reagents and methods for detecting and distinguishing human rhinovirus from other viruses. A kit is provided for detecting and quantifying human rhinovirus in a biological sample.
摘要翻译：用于在生物样品中检测人类鼻病毒核酸的方法包括使用SEQ ID NO：1的正向引物和SEQ ID NO：2的反向引物扩增人bocavirus核苷酸序列产生扩增产物，并测量所述扩增产物以检测所述生物样品中的人类鼻病毒。还提供了用于检测和区分人类鼻病毒与其他病毒的试剂和方法。提供了用于检测和定量生物样品中的人类鼻病毒的试剂盒。

3. 发明授权

US08068619B2 Method and apparatus for noise suppression in a small array microphone system 有权
标题翻译：用于小阵列麦克风系统中噪声抑制的方法和装置
公开(公告)号：US08068619B2
公开(公告)日：2011-11-29
申请号：US11620573
申请日：2007-01-05
申请人： Ming Zhang , Xiaoyan Lu
发明人： Ming Zhang , Xiaoyan Lu
IPC分类号： H04R3/00
CPC分类号： H04R3/005 , G10L15/04 , G10L25/78
摘要： A small array microphone system includes an array microphone having a plurality of microphones and operative to provide a plurality of received signals, each microphone providing one received signal. A first voice activity detector (VAD) provides a first voice detection signal generated using the plurality of received signals to indicate the presence or absence of in-beam desired speech. A second VAD provides a second voice detection signal generated using the plurality of received signals to indicate the presence or absence of out-of-beam noise when in-beam desired speech is absent. A reference signal generator provides a reference signal based on the first voice detection signal, the plurality of received signals, and a beamformed signal, wherein the reference signal has the desired speech suppressed. A beamformer provides the beamformed signal based on the second voice detection signal, the reference signal, and the plurality of received signals, wherein the beamformed signal has noise suppressed. A multi-channel noise suppressor operative to further suppress noise in the beamformed signal and provide an output signal. A speech reliability detector provides a reliability detection signal indicating the reliability of each frequency subband. The first voice detection signal, the second voice detection signal, the reliability detection signal and the output signal are provided to the speech recognition engine.
摘要翻译：小阵列麦克风系统包括具有多个麦克风并且可操作以提供多个接收信号的阵列麦克风，每个麦克风提供一个接收的信号。第一语音活动检测器（VAD）提供使用多个接收信号产生的第一语音检测信号，以指示波束内期望语音的存在或不存在。第二VAD提供使用多个接收信号产生的第二语音检测信号，以在不存在束内期望语音时指示出射外噪声的存在或不存在。参考信号发生器基于第一语音检测信号，多个接收信号和波束形成信号提供参考信号，其中参考信号具有所需的语音抑制。波束形成器基于第二语音检测信号，参考信号和多个接收信号提供波束形成信号，其中波束形成的信号被抑制噪声。一种多声道噪声抑制器，用于进一步抑制波束形成信号中的噪声并提供输出信号。语音可靠性检测器提供表示每个频率子带的可靠性的可靠性检测信号。第一语音检测信号，第二语音检测信号，可靠性检测信号和输出信号被提供给语音识别引擎。

4. 发明申请

US20080175407A1 SYSTEM AND METHOD FOR CALIBRATING PHASE AND GAIN MISMATCHES OF AN ARRAY MICROPHONE 审中-公开
标题翻译：用于校准阵列麦克风的相位和增益误差的系统和方法
公开(公告)号：US20080175407A1
公开(公告)日：2008-07-24
申请号：US11625840
申请日：2007-01-23
申请人： Ming Zhang , Xiaoyan Lu , Lili Chen , Jing Ding , Bo Zhang
发明人： Ming Zhang , Xiaoyan Lu , Lili Chen , Jing Ding , Bo Zhang
IPC分类号： H04R3/00
CPC分类号： H04R3/005
摘要： The invention provides a system for calibrating phase and gain mismatches of an array microphone. The array microphone is installed in a voice interface device and comprises a plurality of microphones. The system comprises a loudspeaker and a computing equipment. The loudspeaker plays a segment of sound to be received by the array microphone. The computing equipment controlls the voice interface device which converts the segment of sound to a plurality of audio signals with the microphones of the array microphone, records the audio signals outputted by the voice interface device at bypass mode without any signal processing, calculates delays between the audio signals, and instructs the voice interface device to adjust phase mismatches between the audio signals according to the delays.
摘要翻译：本发明提供了一种用于校准阵列麦克风的相位和增益失配的系统。阵列麦克风安装在语音接口设备中并且包括多个麦克风。该系统包括扬声器和计算设备。扬声器播放由阵列麦克风接收的声音段。计算设备控制语音接口设备，其利用阵列麦克风的麦克风将声音段转换为多个音频信号，将语音接口设备输出的音频信号以旁路模式记录，无需任何信号处理，音频信号，并指示语音接口设备根据延迟调整音频信号之间的相位不匹配。

5. 发明授权

US07945442B2 Internet communication device and method for controlling noise thereof 有权
标题翻译：互联网通信装置及其噪声控制方法
公开(公告)号：US07945442B2
公开(公告)日：2011-05-17
申请号：US11611185
申请日：2006-12-15
申请人： Ming Zhang , Xiaoyan Lu
发明人： Ming Zhang , Xiaoyan Lu
IPC分类号： G10L21/00
CPC分类号： G10L21/0208 , G10L25/78
摘要： The invention provides an Internet communication device. The Internet communication device plays a remote audio signal received via a network and transmits an audio signal back to the remote party to complete the communication. The Internet communication device comprises a line-in speech detection module and a line-in channel control module. The line-in speech detection module detects whether the remote audio signal is speech or not to generate a remote speech detection result. The line-in channel control module then attenuates the remote audio signal if the remote speech detection result indicates that the remote audio signal is not speech, thus, all noise including non-stationary noise is removed from the remote audio signal.
摘要翻译：本发明提供一种因特网通信设备。互联网通信设备播放通过网络接收到的远程音频信号，并将音频信号发送回对方以完成通信。互联网通信设备包括线路输入语音检测模块和线路输入信道控制模块。线路输入语音检测模块检测远程音频信号是否是语音，以产生远程语音检测结果。如果远程语音检测结果指示远程音频信号不是语音，则线路输入信道控制模块会衰减远程音频信号，从而从远程音频信号中去除包括非平稳噪声的所有噪声。

6. 发明申请

US20090115494A1 Charge pump warm-up current reduction 有权
标题翻译：电荷泵预热电流降低
公开(公告)号：US20090115494A1
公开(公告)日：2009-05-07
申请号：US11983079
申请日：2007-11-07
申请人： Orlando Consuelo , Raymond Zeng , Xiaoyan Lu
发明人： Orlando Consuelo , Raymond Zeng , Xiaoyan Lu
IPC分类号： G05F1/46 , G11C5/14
CPC分类号： G11C5/145 , G11C16/30
摘要： A charge pump circuit includes a voltage controlled oscillator. The voltage controlled oscillator operates at a lower frequency during a warm-up mode, and operates at a higher frequency during a loading mode. The lower frequency operation during the warm-up mode reduces power supply current requirements.
摘要翻译：电荷泵电路包括压控振荡器。压控振荡器在预热模式下以较低的频率运行，并且在加载模式下以更高的频率工作。预热模式下的低频操作降低了电源电流要求。

7. 发明授权

US08351617B2 Method for phase mismatch calibration for an array microphone and phase calibration module for the same 有权
标题翻译：阵列麦克风和相位校准模块的相位不匹配校准方法
公开(公告)号：US08351617B2
公开(公告)日：2013-01-08
申请号：US12352666
申请日：2009-01-13
申请人： Ming Zhang , Xiaoyan Lu
发明人： Ming Zhang , Xiaoyan Lu
IPC分类号： H04R3/00
CPC分类号： H04R3/005 , G10L21/0208 , G10L25/78 , G10L2021/02166
摘要： The invention provides a phase calibration module, calibrating phase mismatch between microphone signals output by a plurality of microphones of an array microphone. In one embodiment, the phase calibration module comprises a subband filter, a delay calculation module, and a delay compensation filter. The subband filter extracts a high frequency component and a low frequency component from each of the microphone signals to obtain a plurality of high-frequency component signals and a plurality of low-frequency component signals. The delay calculation module calculates delays between the low-frequency component signals. The delay compensation filter then compensates the low-frequency component signals for phase mismatches therebetween according to the calculated delays to obtain a plurality of calibrated low-frequency component signals.
摘要翻译：本发明提供一种相位校准模块，用于校准由阵列麦克风的多个麦克风输出的麦克风信号之间的相位失配。在一个实施例中，相位校准模块包括子带滤波器，延迟计算模块和延迟补偿滤波器。子带滤波器从每个麦克风信号中提取高频分量和低频分量，以获得多个高频分量信号和多个低频分量信号。延迟计算模块计算低频分量信号之间的延迟。延迟补偿滤波器然后根据所计算的延迟来补偿低频分量信号之间的相位失配，以获得多个校准的低频分量信号。

8. 发明申请

US20100179806A1 METHOD FOR PHASE MISMATCH CALIBRATION FOR AN ARRAY MICROPHONE AND PHASE CALIBRATION MODULE FOR THE SAME 有权
标题翻译：用于阵列麦克风和相位校准模块的相位误差校准的方法
公开(公告)号：US20100179806A1
公开(公告)日：2010-07-15
申请号：US12352666
申请日：2009-01-13
申请人： Ming Zhang , Xiaoyan Lu
发明人： Ming Zhang , Xiaoyan Lu
IPC分类号： G10L21/00 , H04R3/00
CPC分类号： H04R3/005 , G10L21/0208 , G10L25/78 , G10L2021/02166
摘要： The invention provides a phase calibration module, calibrating phase mismatch between microphone signals output by a plurality of microphones of an array microphone. In one embodiment, the phase calibration module comprises a subband filter, a delay calculation module, and a delay compensation filter. The subband filter extracts a high frequency component and a low frequency component from each of the microphone signals to obtain a plurality of high-frequency component signals and a plurality of low-frequency component signals. The delay calculation module calculates delays between the low-frequency component signals. The delay compensation filter then compensates the low-frequency component signals for phase mismatches therebetween according to the calculated delays to obtain a plurality of calibrated low-frequency component signals.
摘要翻译：本发明提供一种相位校准模块，用于校准由阵列麦克风的多个麦克风输出的麦克风信号之间的相位失配。在一个实施例中，相位校准模块包括子带滤波器，延迟计算模块和延迟补偿滤波器。子带滤波器从每个麦克风信号中提取高频分量和低频分量，以获得多个高频分量信号和多个低频分量信号。延迟计算模块计算低频分量信号之间的延迟。延迟补偿滤波器然后根据所计算的延迟来补偿低频分量信号之间的相位失配，以获得多个校准的低频分量信号。

9. 发明授权

US07667529B2 Charge pump warm-up current reduction 有权
标题翻译：电荷泵预热电流降低
公开(公告)号：US07667529B2
公开(公告)日：2010-02-23
申请号：US11983079
申请日：2007-11-07
申请人： Orlando Consuelo , Raymond Zeng , Xiaoyan Lu
发明人： Orlando Consuelo , Raymond Zeng , Xiaoyan Lu
IPC分类号： G05F1/10 , G05F3/02
CPC分类号： G11C5/145 , G11C16/30
摘要： A charge pump circuit includes a voltage controlled oscillator. The voltage controlled oscillator operates at a lower frequency during a warm-up mode, and operates at a higher frequency during a loading mode. The lower frequency operation during the warm-up mode reduces power supply current requirements.
摘要翻译：电荷泵电路包括压控振荡器。压控振荡器在预热模式下以较低的频率运行，并且在加载模式下以更高的频率工作。预热模式下的低频操作降低了电源电流要求。

10. 发明申请

US20080317259A1 METHOD AND APPARATUS FOR NOISE SUPPRESSION IN A SMALL ARRAY MICROPHONE SYSTEM 有权
标题翻译：用于小阵列麦克风系统噪声抑制的方法和装置
公开(公告)号：US20080317259A1
公开(公告)日：2008-12-25
申请号：US11620573
申请日：2007-01-05
申请人： Ming Zhang , Xiaoyan Lu
发明人： Ming Zhang , Xiaoyan Lu
IPC分类号： H04R3/00 , H04B15/00
CPC分类号： H04R3/005 , G10L15/04 , G10L25/78
摘要： A small array microphone system includes an array microphone having a plurality of microphones and operative to provide a plurality of received signals, each microphone providing one received signal. A first voice activity detector (VAD) provides a first voice detection signal generated using the plurality of received signals to indicate the presence or absence of in-beam desired speech. A second VAD provides a second voice detection signal generated using the plurality of received signals to indicate the presence or absence of out-of-beam noise when in-beam desired speech is absent. A reference signal generator provides a reference signal based on the first voice detection signal, the plurality of received signals, and a beamformed signal, wherein the reference signal has the desired speech suppressed. A beamformer provides the beamformed signal based on the second voice detection signal, the reference signal, and the plurality of received signals, wherein the beamformed signal has noise suppressed. A multi-channel noise suppressor operative to further suppress noise in the beamformed signal and provide an output signal. A speech reliability detector provides a reliability detection signal indicating the reliability of each frequency subband. The first voice detection signal, the second voice detection signal, the reliability detection signal and the output signal are provided to the speech recognition engine.
摘要翻译：小阵列麦克风系统包括具有多个麦克风并且可操作以提供多个接收信号的阵列麦克风，每个麦克风提供一个接收的信号。第一语音活动检测器（VAD）提供使用多个接收信号产生的第一语音检测信号，以指示波束内期望语音的存在或不存在。第二VAD提供使用多个接收信号产生的第二语音检测信号，以在不存在束内期望语音时指示出射外噪声的存在或不存在。参考信号发生器基于第一语音检测信号，多个接收信号和波束形成信号提供参考信号，其中参考信号具有所需的语音抑制。波束形成器基于第二语音检测信号，参考信号和多个接收信号提供波束形成信号，其中波束形成的信号被抑制噪声。一种多声道噪声抑制器，用于进一步抑制波束形成信号中的噪声并提供输出信号。语音可靠性检测器提供表示每个频率子带的可靠性的可靠性检测信号。第一语音检测信号，第二语音检测信号，可靠性检测信号和输出信号被提供给语音识别引擎。

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