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1. 发明授权

US07706855B1 System and method for MR data acquisition with uniform fat suppression 失效
标题翻译：具有均匀脂肪抑制的MR数据采集系统和方法
公开(公告)号：US07706855B1
公开(公告)日：2010-04-27
申请号：US10710555
申请日：2004-07-20
申请人： Agus Priatna , Anthony T. Vu , Xiaoli Zhao
发明人： Agus Priatna , Anthony T. Vu , Xiaoli Zhao
IPC分类号： A61B5/05
CPC分类号： A61B5/055 , G01R33/4828 , G01R33/5602 , G01R33/5607 , G01R33/5608 , G01R33/56308
摘要： A system and method of MR imaging is disclosed that includes reconstruction of MR images with uniform or homogeneous fat suppression. An imaging process is performed using partial asymmetric acquisitions in conjunction with zero-filling of k-space for dynamic contrast-enhanced imaging. Data acquisition is carried out in a relatively short period of time which reduces scan time, reduces the likelihood of subject discomfort and motion-induced artifacts, and increases patient throughput.
摘要翻译：公开了一种MR成像的系统和方法，其包括具有均匀或均匀脂肪抑制的MR图像的重建。使用部分非对称采集与用于动态对比度增强成像的k空间的零填充来执行成像处理。数据采集在相对短的时间内进行，这减少了扫描时间，降低了受试者不适和运动诱发的伪像的可能性，并增加了患者的吞吐量。

2. 发明授权

US07330028B2 Apparatus and method of simultaneous fat suppression, magnetization transfer contrast, and spatial saturation for 3D time-of-flight imaging 有权
标题翻译：同步脂肪抑制，磁化转移对比度和3D飞行时间成像的空间饱和度的装置和方法
公开(公告)号：US07330028B2
公开(公告)日：2008-02-12
申请号：US11162848
申请日：2005-09-26
申请人： Xiaoli Zhao , Anthony T. Vu
发明人： Xiaoli Zhao , Anthony T. Vu
IPC分类号： G01V3/00
CPC分类号： G01R33/56308 , G01R33/4818 , G01R33/4828 , G01R33/4838 , G01R33/5601 , G01R33/5605 , G01R33/5607 , G01R33/5635
摘要： A pulse sequence for time-of-flight (TOF) magnetic resonance angiography (MRA) includes a fatsat segment, a magnetization transfer segment, and a spatial saturation segment that are applied by an MR apparatus to acquire MR data for image reconstruction with improved image quality. The pulse sequence is constructed such that at the beginning of each iteration of the inner loop of a 3D acquisition, a fatsat pulse is applied. After the fatsat pulse, MR data is acquired in a series of imaging segments with well-suppressed fat signal. Effective fat suppression is achieved by sampling central k-space data first, before signal from fat relaxes back to a pre-saturation level. Each imaging segment is immediately preceded by one of a MT pulse or a spatial saturation pulse and immediately followed by the other one of the MT pulse or the spatial saturation pulse.
摘要翻译：飞行时间（TOF）磁共振血管造影（MRA）的脉冲序列包括由MR装置施加的脂肪段，磁化转移段和空间饱和段，以获得具有改进图像的图像重建的MR数据质量。脉冲序列被构造成使得在3D采集的内循环的每次迭代开始时，施加一个脂肪脉冲。在脂肪脉冲之后，在具有良好抑制的脂肪信号的一系列成像段中获取MR数据。首先通过对中心k空间数据进行采样来实现有效的脂肪抑制，之后脂肪信号会放松到预饱和度水平。每个成像片段紧接着是MT脉冲或空间饱和脉冲之一，紧接着是MT脉冲或空间饱和脉冲中的另一个。

3. 发明授权

US07383075B2 Real-time localization monitoring, triggering, and acquisition of 3D MRI 有权
标题翻译：实时定位监测，触发和采集3D MRI
公开(公告)号：US07383075B2
公开(公告)日：2008-06-03
申请号：US10938966
申请日：2004-09-10
申请人： Anthony T. Vu
发明人： Anthony T. Vu
IPC分类号： A61B5/055
CPC分类号： G01R33/482
摘要： A technique embodied in a method and apparatus is disclosed for acquiring MR images in 2D and 3D using a common pulse sequence switchable in real-time. The technique includes identifying a 3D imaging volume and applying a 3D pulse sequence having the slice encoding and rewinder gradients disabled in one dimension. The technique then allows localizing and monitoring by acquiring 2D MR data. When it is desirable to enter a 3D imaging mode, the slice encoding and rewinder gradients are re-enabled in the common pulse sequence for acquisition of 3D MR data.
摘要翻译：公开了一种体现在方法和装置中的技术，用于使用可实时切换的公共脉冲序列在2D和3D中获取MR图像。该技术包括识别3D成像体积并应用在一个维度中禁用切片编码和回绕器梯度的3D脉冲序列。该技术允许通过获取2D MR数据进行本地化和监视。当需要进入3D成像模式时，在用于采集3D MR数据的公共脉冲序列中重新启用切片编码和重绕梯度。

4. 发明申请

US20100097061A1 APPARATUS AND METHOD FOR DETECTING AND CLASSIFYING ATHEROSCLEROTIC PLAQUE HEMORRHAGE 有权
标题翻译：用于检测和分类甲状旁腺素HEMORRHAGE的装置和方法
公开(公告)号：US20100097061A1
公开(公告)日：2010-04-22
申请号：US12254630
申请日：2008-10-20
申请人： David C. Zhu , J. Kevin DeMarco , Anthony T. Vu
发明人： David C. Zhu , J. Kevin DeMarco , Anthony T. Vu
IPC分类号： G01R33/483 , A61B5/055
CPC分类号： G01R33/5615 , A61B5/02007 , A61B5/055 , A61B5/7264 , G01R33/50 , G01R33/5602 , G01R33/5607 , G01R33/5635
摘要： A system and method for detecting atherosclerotic plaque hemorrhage includes a controller programmed to apply a non-selective inversion recovery RF pulse to a region of interest, apply a plurality of encoding sequences to the region of interest to cause generation of a plurality of echoes during application of each encoding sequence. The controller is further programmed to acquire three dimensional MR data from the region of interest during generation of each of the plurality of echoes, identify a hemorrhage based on the three dimensional MR data, characterize a type of the hemorrhage, and reconstruct an image based on the three dimensional MR data, the image comprising the characterized hemorrhage.
摘要翻译：用于检测动脉粥样硬化斑块出血的系统和方法包括被编程为向感兴趣区域施加非选择性反转恢复RF脉冲的控制器，在感兴趣的区域应用多个编码序列以在应用期间产生多个回波的每个编码序列。控制器进一步被编程为在多个回波中的每一个的产生期间从感兴趣的区域获取三维MR数据，基于三维MR数据识别出血，表征出血的类型，以及基于三维MR数据，该图像包括特征性出血。

5. 发明授权

US07078900B2 Method and system of determining parameters for MR data acquisition with real-time B1 optimization 有权
标题翻译：通过实时B1优化确定MR数据采集参数的方法和系统
公开(公告)号：US07078900B2
公开(公告)日：2006-07-18
申请号：US10897477
申请日：2004-07-23
申请人： Anthony T. Vu
发明人： Anthony T. Vu
IPC分类号： G01V3/00
CPC分类号： G01R33/583 , G01R33/288 , G01R33/5659
摘要： The present invention provides a system and method of MR scan prescription to achieve in a fast, simple, and effective manner the optimal peak excitation field strength for a given pulse shape and flip angle such that the minimum TR for the MR scan can be optimized and based on SAR constraints. The present invention provides a technique to obtain optimal B1 parameters for an arbitrary shape and flip angle of an excitation pulse in real-time while satisfying SAR and/or RF hardware limits to determine the minimum achievable repetition time for a pulse sequence. The present invention is particularly applicable with breath-hold and cardiac imaging techniques that are carried out at relatively high field strengths.
摘要翻译：本发明提供了一种用于以快速，简单和有效的方式实现给定脉冲形状和翻转角的最佳峰值激励场强的MR扫描处方的系统和方法，使得可以优化用于MR扫描的最小TR; 基于SAR限制。本发明提供一种技术，用于实时获得激发脉冲的任意形状和翻转角的最佳B 1参数，同时满足SAR和/或RF硬件限制以确定最小可实现的重复时间用于脉冲序列。本发明特别适用于以较高场强进行的呼吸保持和心脏成像技术。

6. 发明授权

US07705593B1 Apparatus and method for detecting and classifying atherosclerotic plaque hemorrhage 有权
标题翻译：用于检测和分类动脉粥样硬化斑块出血的装置和方法
公开(公告)号：US07705593B1
公开(公告)日：2010-04-27
申请号：US12254630
申请日：2008-10-20
申请人： David C. Zhu , J. Kevin DeMarco , Anthony T. Vu
发明人： David C. Zhu , J. Kevin DeMarco , Anthony T. Vu
IPC分类号： G01V3/00
CPC分类号： G01R33/5615 , A61B5/02007 , A61B5/055 , A61B5/7264 , G01R33/50 , G01R33/5602 , G01R33/5607 , G01R33/5635
摘要： A system and method for detecting atherosclerotic plaque hemorrhage includes a controller programmed to apply a non-selective inversion recovery RF pulse to a region of interest, apply a plurality of encoding sequences to the region of interest to cause generation of a plurality of echoes during application of each encoding sequence. The controller is further programmed to acquire three dimensional MR data from the region of interest during generation of each of the plurality of echoes, identify a hemorrhage based on the three dimensional MR data, characterize a type of the hemorrhage, and reconstruct an image based on the three dimensional MR data, the image comprising the characterized hemorrhage.
摘要翻译：用于检测动脉粥样硬化斑块出血的系统和方法包括被编程为向感兴趣区域施加非选择性反转恢复RF脉冲的控制器，在感兴趣的区域应用多个编码序列以在应用期间产生多个回波的每个编码序列。控制器进一步被编程为在多个回波中的每一个的产生期间从感兴趣的区域获取三维MR数据，基于三维MR数据识别出血，表征出血的类型，以及基于三维MR数据，该图像包括特征性出血。

7. 发明授权

US07671590B2 Method and apparatus of multi-echo MR data acquisition with non-discrete flip angle train 有权
标题翻译：具有非离散翻转列车的多回波MR数据采集方法与装置
公开(公告)号：US07671590B2
公开(公告)日：2010-03-02
申请号：US11686413
申请日：2007-03-15
申请人： Hari Hariharan , Anthony T. Vu
发明人： Hari Hariharan , Anthony T. Vu
IPC分类号： G01V3/00
CPC分类号： G01R33/5615
摘要： An imaging technique is disclosed to reduce ringing artifacts from amplitude decay in MR multi-echo acquisition. A flip angle train is determined to match scan parameters for an MR scan to acquire MR data from a given tissue. Reducing the effects of amplitude decay in the echo signal reduces ringing artifacts and thereby improves image quality.
摘要翻译：公开了一种成像技术，以减少MR多回波采集中振幅衰减造成的振铃伪影。确定一个翻转列车以匹配用于MR扫描的扫描参数以从给定的组织获取MR数据。降低回波信号中振幅衰减的影响可减少振铃伪影，从而提高图像质量。

8. 发明授权

US07265547B2 Method and apparatus for acquiring MR data with a segmented multi-shot radial fan beam encoding order 有权
标题翻译：用分段多镜径向风扇光束编码顺序获取MR数据的方法和装置
公开(公告)号：US07265547B2
公开(公告)日：2007-09-04
申请号：US11162621
申请日：2005-09-16
申请人： Anthony T. Vu
发明人： Anthony T. Vu
IPC分类号： G01V3/00
CPC分类号： A61B5/055 , G01R33/4818 , G01R33/4822 , G01R33/4826 , G01R33/4828 , G01R33/5602 , G01R33/5607 , G01R33/5613 , G01R33/5614 , G01R33/56518
摘要： An MR imaging apparatus is presented and includes a plurality of gradient coils positioned about a bore of a magnet to impress a polarizing magnetic field. An RF transceiver system and an RF switch are controlled by a pulse module to transmit and receive RF signals to and from an RF coil assembly to acquire MR images. The MR imaging apparatus also includes a computer programmed to apply a 3D imaging sequence and acquire MR data using a segmented acquisition. The computer is further programmed to reconstruct an image from the MR data that is substantially free of eddy current induced artifacts.
摘要翻译：提出了一种MR成像装置，并且包括围绕磁体的孔定位的多个梯度线圈以施加偏振磁场。 RF收发器系统和RF开关由脉冲模块控制以向RF线圈组件发射和接收RF信号以从RF线圈组件接收RF信号以获取MR图像。 MR成像设备还包括被编程为应用3D成像序列并且使用分段采集来获取MR数据的计算机。计算机还被编程为从基本上没有涡流引起的伪像的MR数据重建图像。

9. 发明授权

US07800367B2 Method and apparatus for generating T2* weighted magnetic resonance images 有权
标题翻译：用于产生T2 *加权磁共振图像的方法和装置
公开(公告)号：US07800367B2
公开(公告)日：2010-09-21
申请号：US12060985
申请日：2008-04-02
申请人： Ravi Bhardwaj , Anthony T. Vu , Ramesh Venkatesan
发明人： Ravi Bhardwaj , Anthony T. Vu , Ramesh Venkatesan
IPC分类号： G01V3/00
CPC分类号： G01R33/5615 , G01R33/5608 , G01R33/5616
摘要： A method for generating a susceptibility (or T2*) weighted magnetic resonance (MR) image includes defining a pulse sequence having a plurality of gradient echoes and acquiring MR data for each of the plurality of gradient echoes. A weighting function is applied to image data for each gradient echo such as MR data (e.g., k-space data) or magnitude images associated with each gradient echo. A susceptibility weighted image is generated by combining the image data for each gradient echo based on at least the application of the weighting function.
摘要翻译：用于产生磁化率（或T2 *）加权磁共振（MR）图像的方法包括定义具有多个梯度回波的脉冲序列并且为多个梯度回波中的每一个采集MR数据。加权函数被应用于每个梯度回波的图像数据，例如MR数据（例如，k空间数据）或与每个梯度回波相关联的幅度图像。至少基于加权函数的应用，通过组合每个梯度回波的图像数据来生成敏感性加权图像。

10. 发明申请

US20090251140A1 METHOD AND APPARATUS FOR GENERATING T2* WEIGHTED MAGNETIC RESONANCE IMAGES 有权
标题翻译：用于产生T2 *加权磁共振图像的方法和装置
公开(公告)号：US20090251140A1
公开(公告)日：2009-10-08
申请号：US12060985
申请日：2008-04-02
申请人： Ravi Bhardwaj , Anthony T. Vu , Ramesh Venkatesan
发明人： Ravi Bhardwaj , Anthony T. Vu , Ramesh Venkatesan
IPC分类号： G01R33/54
CPC分类号： G01R33/5615 , G01R33/5608 , G01R33/5616
摘要： A method for generating a susceptibility (or T2*) weighted magnetic resonance (MR) image includes defining a pulse sequence having a plurality of gradient echoes and acquiring MR data for each of the plurality of gradient echoes. A weighting function is applied to image data for each gradient echo such as MR data (e.g., k-space data) or magnitude images associated with each gradient echo. A susceptibility weighted image is generated by combining the image data for each gradient echo based on at least the application of the weighting function.
摘要翻译：用于产生磁化率（或T2 *）加权磁共振（MR）图像的方法包括定义具有多个梯度回波的脉冲序列并且为多个梯度回波中的每一个采集MR数据。加权函数被应用于每个梯度回波的图像数据，例如MR数据（例如，k空间数据）或与每个梯度回波相关联的幅度图像。至少基于加权函数的应用，通过组合每个梯度回波的图像数据来生成敏感性加权图像。

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