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1. 发明授权

US5949532A Method and apparatus for Raman correlation spectroscopy 失效
标题翻译：拉曼相关光谱的方法和装置
公开(公告)号：US5949532A
公开(公告)日：1999-09-07
申请号：US900714
申请日：1997-07-28
申请人： Wolfgang Schrof , Jurgen Klingler , Dieter Horn
发明人： Wolfgang Schrof , Jurgen Klingler , Dieter Horn
IPC分类号： G01N21/65 , G01J3/28 , G01J3/44 , G01J3/457 , G01N21/64
CPC分类号： G01J3/457 , G01J3/44 , G01J2003/2866
摘要： A method and an apparatus for determining diffusion parameters, concentration, size or flow behavior of particles in a sample, exciting light of a light source being directed into the sample, Raman scattered light being collected from an observed volume of the sample and being passed on to a spectrograph where it is resolved into spectral lines, the intensity of at least one spectral line being measured at least 10 times per second by means of one photodetector each, and the measured intensity values for the respective spectral line being used, via a fluctuation analysis, preferably an autocorrelation or a frequency analysis, to calculate diffusion parameters, concentration, size or flow behavior of the particle to which the spectral line in question can be assigned. With this method, it is also possible for signals of different spectral lines or bands, or signals of Raman scattered light, quasi-elastically scattered light and fluorescence light to be correlated with one another.
摘要翻译：用于确定样品中颗粒的扩散参数，浓度，尺寸或流动行为的方法和装置，激发被引入样品的光源的激发光，从观察体积的样品中收集的拉曼散射光，并被传递对于其被分解成谱线的光谱仪，通过一个光电检测器每秒至少测量10次光谱线的强度，以及通过波动测量各光谱线的测量强度值分析，优选自相关或频率分析，以计算可以分配所讨论的谱线的粒子的扩散参数，浓度，尺寸或流动行为。通过该方法，也可以使不同谱线或频带的信号，或拉曼散射光，准弹性散射光和荧光的信号彼此相关。

2. 发明授权

US5815262A Apparatus for parallelized two-photon fluorescence correlation spectroscopy (TPA-FCS), and the use thereof for screening active compounds 失效
标题翻译：用于平行化双光子荧光相关光谱仪（TPA-FCS）的装置及其用于筛选活性化合物的用途
公开(公告)号：US5815262A
公开(公告)日：1998-09-29
申请号：US700856
申请日：1996-08-21
申请人： Wolfgang Schrof , Jurgen Klingler , Dieter Horn , Elmar Mayer
发明人： Wolfgang Schrof , Jurgen Klingler , Dieter Horn , Elmar Mayer
IPC分类号： G01N21/64 , G01J3/30
CPC分类号： G01N21/6402 , G01J3/4406 , G01N21/645
摘要： An apparatus for carrying out laser-induced two-photon fluorescence correlation spectroscopy (TPA-FCS), in which a plurality of volumes (6) are delimited or defined in the apparatus in such a way that samples (3) introduced into these volumes can be excited and observed in parallel by means of a single laser (1). Such an apparatus is e.g. used to screen active compounds.
摘要翻译：一种用于进行激光诱导的双光子荧光相关光谱（TPA-FCS）的装置，其中在装置中限定或限定多个体积（6），使得引入这些体积的样品（3）可以通过单个激光（1）激发并平行观察。这样的装置是例如用于筛选活性化合物。

3. 发明授权

US5982485A Determination of interface adsorption 失效
标题翻译：界面吸附的测定
公开(公告)号：US5982485A
公开(公告)日：1999-11-09
申请号：US92969
申请日：1998-06-08
申请人： Wolfgang Schrof , Frank Runge , Jurgen Klingler
发明人： Wolfgang Schrof , Frank Runge , Jurgen Klingler
IPC分类号： G01B11/28 , G01N13/00 , G01N13/02 , G01D3/44
CPC分类号： G01N13/02 , G01N2013/0241
摘要： A method and an apparatus for determining the coverage of the interface between a liquid first phase and a liquid or gaseous second phase by at least one molecular species, at least the following procedural steps being carried out successively: the generation of a stream of droplets which contain at least the liquid first phase, in such a way that the droplets move along a droplet trajectory, and the non-contact determination of a measure of the coverage of the interface by the at least one molecular species at at least two different points along the droplet trajectory.
摘要翻译：一种用于通过至少一种分子种类确定液体第一相和液体或气态第二相之间的界面的覆盖度的方法和装置，至少以下程序步骤依次进行：产生液滴流至少包含液体第一相，使得液滴沿着液滴轨迹移动，并且通过至少一个分子种类在至少两个不同点处的界面的覆盖范围的非接触确定液滴轨迹。

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