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1. 发明授权

US06313247B1 Cinchonan based chiral selectors for separation of stereoisomers 失效
标题翻译：用于分离立体异构体的Cinchonan基手性选择剂
公开(公告)号：US06313247B1
公开(公告)日：2001-11-06
申请号：US09194892
申请日：1999-11-17
申请人： Wolfgang Lindner , Michael Laemmerhofer , Norbert Maier
发明人： Wolfgang Lindner , Michael Laemmerhofer , Norbert Maier
IPC分类号： C07D45304
CPC分类号： C07D453/04 , Y10T428/2993 , Y10T428/2998
摘要： Enantioseparation methods using chemical compounds which contain the chiral 9,11-substituted-10,11-dihydro-cinchonan skeleton (9,11-Subst.-DHC) and the precursors thereof with the 9-substituted cinchonan skeleton (9-Subst.-C) are described and discussed. The chiral compounds of the present invention are based on cinchonan derivatives containing amide structure elements which support effectively and co-operatively the enantioseparation of chiral acidic selectands involving also ion-pair and ion-exchange binding mechanism between the strong amino group of the selector and the acidic group of the selectand. The methods of enantioseparation of the present invention are related to stereoselective liquid-liquid and liquid-solid type extraction principles and fractionated crystallization employing cinchonan derivative type selectors. In one embodiment of the present invention the chiral selector is immobilized onto support material or is incorporated within a polymer or is part of a polymer used for liquid-solid enantioseparation techniques.
摘要翻译：使用含有手性9,11-取代-10,11-二氢 - 辛可诺骨架（9,11-对 - DHC）的化合物和其9-前体与9-取代的辛可诺骨架（9-对 - C）进行了描述和讨论。本发明的手性化合物是基于含有酰胺结构元件的肉桂酸衍生物，其有效和可操作地支持手性酸性选择素的对映体分离，其还涉及选择剂的强氨基与选择剂的强氨基之间的离子对和离子交换结合机制酸性组的选择。本发明的对映体分离方法涉及立体选择性液体 - 液体和液体 - 固体萃取原理，并且使用辛醌衍生物型选择器进行分级结晶。在本发明的一个实施方案中，手性选择剂被固定在载体材料上，或者被结合到聚合物中，或者是用于液体 - 固体对映体分离技术的聚合物的一部分。

2. 发明申请

US20120016121A1 Process for the separation of enantiomers of 3,6-dihydro-1,3,5-triazine derivatives 有权
标题翻译：分离3,6-二氢-1,3,5-三嗪衍生物的对映异构体的方法
公开(公告)号：US20120016121A1
公开(公告)日：2012-01-19
申请号：US13258629
申请日：2010-02-26
申请人： Matthias Helmreich , Claus Peter Niesert , Michael Schulte , Wolfgang Lindner , Michael Laemmerhofer , Christian Hoffmann
发明人： Matthias Helmreich , Claus Peter Niesert , Michael Schulte , Wolfgang Lindner , Michael Laemmerhofer , Christian Hoffmann
IPC分类号： C07D251/18
CPC分类号： C07D251/10
摘要： Method for the chromatographic separation of compounds of the formula (I), in which R1, R2, R3, R4, R5, R6 have the meanings indicated in claim 1, and acid-addition salts thereof, characterised in that the separation is carried out on a chiral ion-exchanger material.
摘要翻译：式（I）化合物（其中R 1，R 2，R 3，R 4，R 5，R 6具有权利要求1所示的含义）的色谱分离方法及其酸加成盐，其特征在于分离进行在手性离子交换材料上。

3. 发明授权

US08895732B2 Process for the separation of enantiomers of 3,6-dihydro-1,3,5-triazine derivatives 有权
标题翻译：分离3,6-二氢-1,3,5-三嗪衍生物的对映异构体的方法
公开(公告)号：US08895732B2
公开(公告)日：2014-11-25
申请号：US13258629
申请日：2010-02-26
申请人： Matthias Helmreich , Claus Peter Niesert , Michael Schulte , Wolfgang Lindner , Michael Laemmerhofer , Christian Hoffmann
发明人： Matthias Helmreich , Claus Peter Niesert , Michael Schulte , Wolfgang Lindner , Michael Laemmerhofer , Christian Hoffmann
IPC分类号： C07D251/10
CPC分类号： C07D251/10
摘要： Method for the chromatographic separation of compounds of the formula (I), in which R1, R2, R3, R4, R5, R6 have the meanings indicated in Claim 1, and acid-addition salts thereof, characterized in that the separation is carried out on a chiral ion-exchanger material.
摘要翻译：式（I）化合物（其中R 1，R 2，R 3，R 4，R 5，R 6具有权利要求1所述的含义）的色谱分离方法及其酸加成盐，其特征在于分离进行在手性离子交换材料上。

4. 发明申请

US20110121229A1 ENANTIOSELECTIVE ZWITTERIONIC ION-EXCHANGE MATERIAL 审中-公开
标题翻译： ENANTILECLECTIVE ZWITTERICI离子交换材料
公开(公告)号：US20110121229A1
公开(公告)日：2011-05-26
申请号：US12992558
申请日：2009-05-11
申请人： Wolfgang Lindner , Michael Laemmerhofer , Christian Hoffmann
发明人： Wolfgang Lindner , Michael Laemmerhofer , Christian Hoffmann
IPC分类号： C09K3/00
CPC分类号： B01D15/364 , B01J20/286 , B01J20/29 , B01J20/3219 , B01J20/3251 , B01J20/3253 , B01J20/3255 , B01J20/3285 , B01J39/04 , B01J39/26 , B01J43/00 , B01J2220/54 , B01J2220/58 , G01N1/34 , B01J41/04 , B01J41/20
摘要： An enantioselective zwitterionic ion-exchange material comprising a chiral selector component (SO) comprising at least one cation exchange group and at least one anion exchange group and a carrier, carrying said selector component, wherein the chiral selector component comprises at least one chiral linker moiety to connect said ion exchange groups in a non-macro-cyclic fashion, and said chiral linker moiety contains at least one π-π interaction site.
摘要翻译：一种对映选择性两性离子交换材料，其包含携带所述选择剂组分的包含至少一个阳离子交换基团和至少一个阴离子交换基团和载体的手性选择剂组分（SO），其中手性选择剂组分包含至少一个手性接头部分以非大环循环方式连接所述离子交换基团，并且所述手性连接体部分含有至少一个＆amp; 互动网站

5. 发明申请

US20110150956A1 Immobilized 1,2-benzisothiazolin-3-one 有权
标题翻译：固定化的1,2-苯并异噻唑啉-3-酮
公开(公告)号：US20110150956A1
公开(公告)日：2011-06-23
申请号：US12930629
申请日：2011-01-12
申请人： Wolfgang Lindner
发明人： Wolfgang Lindner
IPC分类号： A01N25/00 , C07F3/06 , A01N55/02 , A01P1/00
CPC分类号： A61K31/555 , C07B2200/11 , C07F3/003
摘要： The present invention provides novel antimicrobial immobilized 1,2-benzisothiazolin-3-one/zinc oxide (BIT/ZnO) complexes useful as antimicrobial agents because of their resistance to being leached from the substrate to which they are attached. The present invention is also directed to methods for preparing the BIT/ZnO complexes, to BIT/ZnO complexes prepared by the novel methods, to methods for using the BIT/ZnO complexes to inhibit microbial growth or reduce the level of bacteria on the surface of a substrate, and to substrates protected to from microbial attack by being treated with the BIT/ZnO complexes. The present invention is further directed to compositions comprising 1,2-benzisothiazolin-3-one which has been immobilized with zinc oxide.
摘要翻译：本发明提供了新型的抗微生物固定化的1,2-苯并异噻唑啉-3-酮/氧化锌（BIT / ZnO）复合物，因为它们耐受从它们所附着的基质中浸出。本发明还涉及用于制备BIT / ZnO复合物的方法，通过新方法制备的BIT / ZnO复合物，使用BIT / ZnO复合物抑制微生物生长或降低表面上的细菌水平的方法底物和通过用BIT / ZnO复合物处理而被保护免受微生物侵袭的底物。本发明还涉及已经用氧化锌固定的1,2-苯并异噻唑啉-3-酮的组合物。

6. 发明申请

US20050131087A1 Enantioselective cation-exchange materials 失效
标题翻译：对映选择性阳离子交换材料
公开(公告)号：US20050131087A1
公开(公告)日：2005-06-16
申请号：US10503689
申请日：2003-02-14
申请人： Wolfgang Lindner , Michael Lammerhofer
发明人： Wolfgang Lindner , Michael Lammerhofer
IPC分类号： B01J20/291 , B01J39/04 , B01J39/16 , B01J39/26 , G01N30/88 , C08F2/00
CPC分类号： B01J39/17 , B01J39/05
摘要： The present invention relates to an enantioselective cation-exchange material, comprising a chiral selector (1), composed of a chiral component (2) and at least one cation-exchange group (X), a spacer (3) and a carrier (4). The cation-exchange material is characterized in that the chiral component (2) has a molecular weight of less than 1,000 and the at least one cation-exchange group (X) is an acid group having a pKa
摘要翻译：本发明涉及一种对映选择性阳离子交换材料，其包括由手性组分（2）和至少一个阳离子交换基团（X），间隔物（3）和载体（4）组成的手性选择剂（1））。阳离子交换材料的特征在于手性组分（2）的分子量小于1,000，并且至少一个阳离子交换基团（X）是pKa <4.0的酸基团。

7. 发明授权

US5252321A Biocidal polymers and polymer dispersions, processes for their preparation and their use 失效
标题翻译：杀生物聚合物和聚合物分散体，其制备方法及其用途
公开(公告)号：US5252321A
公开(公告)日：1993-10-12
申请号：US994138
申请日：1992-12-21
申请人： Hans-Ullrich Huth , Wolfgang Lindner
发明人： Hans-Ullrich Huth , Wolfgang Lindner
IPC分类号： C08L101/00 , A01N47/18 , C07D235/32 , C08F20/52 , C08F30/02 , C08F220/58 , C08F230/02 , C08F246/00 , C08L101/02 , A61K9/10
CPC分类号： C08F246/00 , A01N47/18
摘要： Preparation of biocidal polymers and copolymers based on free radical-polymerizable and copolymerizable ethylenically unsaturated monomers containing monomer units composed of BCM salts of ethylenically unsaturated carboxylic acids, sulfonic acids or phosphonic acids, solutions thereof and preferably aqueous dispersions thereof. Processes for their preparation and their use as fungicidal and algicidal impregnating agents, paints and finishing agents for scumbles and dispersion paints providing protection against blue staining on wood, for synthetic resin renderings, for exposed concrete paints and for textile finishing agents.
摘要翻译：制备基于可自由基聚合和可共聚的烯属不饱和单体的杀生物聚合物和共聚物，其含有由烯键式不饱和羧酸，磺酸或膦酸的BCM盐，其溶液和优选其水分散体组成的单体单元。它们的制备方法及其作为杀真菌剂和杀藻剂浸渍剂，涂料和整理剂的用途，用于提供防止木材上的蓝色染色，用于合成树脂效果，用于暴露的混凝土涂料和纺织品整理剂的防污染和分散涂料。

8. 发明授权

US4434070A Granulate-form powder agglomerates of pulverulent rubber chemicals and a process for production 失效
标题翻译：粉状橡胶化学品颗粒状粉末附聚物和生产工艺
公开(公告)号：US4434070A
公开(公告)日：1984-02-28
申请号：US263028
申请日：1981-05-12
申请人： Wolfgang Lindner , G/u/ nter Arend , Carl-Dieter Barnikel , G/u/ nter Frauenkron
发明人： Wolfgang Lindner , G/u/ nter Arend , Carl-Dieter Barnikel , G/u/ nter Frauenkron
IPC分类号： C08K9/08 , B01J2/20 , B29B9/00 , B29B9/06 , B29B15/00 , B29B15/02 , C08J3/22 , C08K9/00 , C08L7/00 , C08L21/00 , C08C4/00 , B29H1/10
CPC分类号： B29B9/06 , B01J2/20 , C08J3/22 , C08J2321/00
摘要： Granulate-form agglomerates of pulverulent rubber chemicals having a maximum primary grain size of 500 .mu.m , an active substance content of at least 90% by weight and an assessment (a) in the intermixing test of at the most 1.5, (b) in the dust proportion test of at the most 10, (c) in the fine material proportion test of at the most 5 and (d) in the falling test of at the most 70, as well as a process for its production characterized in that the pulverulent rubber chemicals of a maximum primary grain size of 500 .mu.m are mixed with a moistening agent and/or a lubricant and are supplied to a double shaft screw granulator with forced conveyance, in which the spacing between the nozzle plate and the vertically cut screw ends is between 0 and 1.6 mm, whereby the compression ratio K.sub.D is between 1:6 and 1:1.5 and the ratio of nozzle channel length to nozzle channel diameter is between 1 and 6, and whereby the specific granulation work is from 2 to 40 Wh/kg, the rubber chemicals are forced axially through a nozzle perforating plate, the issuing strands are severed or are allowed to break-off and are then dried.
摘要翻译：具有最大初级粒度为500μm，活性物质含量为至少90重量％的粉末状橡胶化学品颗粒状附聚物和评估（a）在混合试验中最多为1.5，（b）在最多10个（c）的最大粉尘比例试验，（c）在最多5次的试验中，（d）在最多70次的下降试验中的精细材料比例试验，以及其制造方法，其特征在于，将最大一次粒径为500μm的粉末状橡胶化学品与润湿剂和/或润滑剂混合并供给到强制输送的双轴螺杆造粒机，其中喷嘴板和垂直切割的螺杆之间的间距端部在0和1.6mm之间，由此压缩比KD在1:6和1:1.5之间，并且喷嘴通道长度与喷嘴通道直径之比在1和6之间，由此特定造粒作业是2到40 Wh / kg，橡胶化学品被迫轴向地穿过喷嘴穿孔板，发出股线被切断或被允许断裂，然后被干燥。

9. 发明授权

US07652048B2 Water-based, antimicrobially active, dispersion concentrates 有权
标题翻译：水性，抗微生物活性，分散浓缩液
公开(公告)号：US07652048B2
公开(公告)日：2010-01-26
申请号：US11800411
申请日：2007-05-04
申请人： Werner Bussmann , Burkhard Roessler , Wolfgang Lindner
发明人： Werner Bussmann , Burkhard Roessler , Wolfgang Lindner
IPC分类号： A61K31/425
CPC分类号： A01N47/12 , A01N43/70 , A01N43/80 , A01N47/30 , A01N25/04 , A01N25/22 , A01N25/30 , A01N2300/00
摘要： Highly concentrated, water-based dispersions of certain lipophilic and/or hydrophobic antimicrobially active materials are stabilized to a surprising degree by a surfactant combination including a nonionic acrylic graft copolymer surfactant and a alkoxylated polyarylphenol phosphate ester surfactant. The active materials may be present in dispersion concentrates of the present invention singly or in useful combinations. The active materials are selected from the group of fungicides and bactericides consisting of 1,2-benzisothiazol-3(2H)-one; 2-octyl-2H-isothiazol-3-one; 5-chloro-2-methyl-2H-isothiazol-3-one; 2-methyl-2H-isothiazol-3-one; pyrithione zinc; 3-iodo-2-propynyl butylcarbamate; 2-methylthio-4-ethylamino-6-tert-butylamino-s-triazine; and 3-(4-isopropylphenyl)-1,1-dimethylurea, and mixtures thereof. The dispersion concentrates may be efficiently shipped and stored, and subsequently diluted with water to produce less concentrated dispersions when desired. Even at relatively high concentrations, the dispersion compositions of the present invention can be stored for months or years without significant loss of stability.
摘要翻译：通过包括非离子丙烯酸接枝共聚物表面活性剂和烷氧基化聚芳基酚磷酸酯表面活性剂的表面活性剂组合将某些亲油和/或疏水性抗微生物活性材料的高度浓缩的水基分散体稳定到惊人的程度。活性物质可以单独存在或以有用的组合存在于本发明的分散体浓缩物中。活性物质选自由1,2-苯并异噻唑-3（2H） - 酮组成的杀真菌剂和杀菌剂; 2-辛基-2H-异噻唑-3-酮; 5-氯-2-甲基-2H-异噻唑-3-酮; 2-甲基-2H-异噻唑-3-酮; 吡啶硫酮锌 3-碘-2-丙炔基丁基氨基甲酸酯; 2-甲硫基-4-乙基氨基-6-叔丁基氨基-s-三嗪; 和3-（4-异丙基苯基）-1,1-二甲基脲及其混合物。分散浓缩物可以有效地运输和储存，然后在需要时用水稀释以产生较少浓度的分散体。即使在相对高的浓度下，本发明的分散体组合物也可以保存数月或数年，而不会明显地损失稳定性。

10. 发明申请

US20070275945A1 Immobilized 1,2-benzisothiazolin-3-one 有权
标题翻译：固定化的1,2-苯并异噻唑啉-3-酮
公开(公告)号：US20070275945A1
公开(公告)日：2007-11-29
申请号：US11440965
申请日：2006-05-25
申请人： Wolfgang Lindner
发明人： Wolfgang Lindner
IPC分类号： A61K31/555 , C07F3/06
CPC分类号： C07F3/003 , A61K31/555 , C07B2200/11
摘要： The present invention provides novel antimicrobial immobilized 1,2-benzisothiazolin-3-one/zinc oxide (BIT/ZnO) complexes useful as antimicrobial agents because of their resistance to being leached from the substrate to which they are attached. The present invention is also directed to methods for preparing the BIT/ZnO complexes, to BIT/ZnO complexes prepared by the novel methods, to methods for using the BIT/ZnO complexes to inhibit microbial growth or reduce the level of bacteria on the surface of a substrate, and to substrates protected from microbial attack by being treated with the BIT/ZnO complexes. The present invention is further directed to compositions comprising 1,2-benzisothiazolin-3-one which has been immobilized with zinc oxide.
摘要翻译：本发明提供了新型的抗微生物固定化的1,2-苯并异噻唑啉-3-酮/氧化锌（BIT / ZnO）复合物，因为它们耐受从它们所附着的基质中浸出。本发明还涉及用于制备BIT / ZnO复合物的方法，通过新方法制备的BIT / ZnO复合物，使用BIT / ZnO复合物抑制微生物生长或降低表面上的细菌水平的方法底物，以及通过用BIT / ZnO复合物处理而防止微生物侵袭的底物。本发明还涉及已经用氧化锌固定的1,2-苯并异噻唑啉-3-酮的组合物。

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