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1. 发明授权

US4431006A Passive ultrasound needle probe locator 失效
标题翻译：被动超声针探针定位器
公开(公告)号：US4431006A
公开(公告)日：1984-02-14
申请号：US337899
申请日：1982-01-07
申请人： William S. Trimmer , Bayard Gardineer, Jr. , Andreas Hadjicostis
发明人： William S. Trimmer , Bayard Gardineer, Jr. , Andreas Hadjicostis
IPC分类号： A61B1/00 , A61B10/00 , A61B10/02 , A61B17/32 , A61B17/34
CPC分类号： A61B10/0233 , A61B1/00142 , A61B17/34 , A61B8/0841 , A61B2017/320088 , A61B2017/3413
摘要： A solid steel stylet is carried coaxially within a hollow biopsy needle. The stylet carries a matching layer at its tip, such that when the needle and stylet are inserted into the body, ultrasound energy impinging on the needle tip is converted to pressure waves which are conveyed back up the stylet. An ultrasound transducer located outside the body is coupled to receive sonic energy from the stylet, and to convert it to electrical energy for coordination with, and superposition upon the image of the system.
摘要翻译：固体钢探针同轴地在中空活检针内携带。探针在其尖端处携带匹配层，使得当针和探针插入身体时，撞击针尖的超声波能量被转换成在探针上传送的压力波。位于身体外部的超声换能器被耦合以从探针接收声能，并将其转换成电能以与系统的图像协调和叠加。

2. 发明授权

US11109909B1 Image guided intravascular therapy catheter utilizing a thin ablation electrode 有权
公开(公告)号：US11109909B1
公开(公告)日：2021-09-07
申请号：US16700185
申请日：2019-12-02
申请人： Andreas Hadjicostis
发明人： Andreas Hadjicostis
IPC分类号： A61B18/14 , A61B8/12 , G02B27/09 , G10K11/30 , A61M25/01 , G02B1/04 , A61B18/00
摘要： A method of forming a sound lens having a coating of a first metal, that utilizes a lens-shaped piece of heat resistant material, having a convex major surface, and having a sonic impedance similar to that of human tissue, taken from a group consisting essentially of high temperature plastics and silicone. In the method, the convex major surface is sputter coated with a layer of the first metal, less than 10 microns thick.

3. 发明授权

US08414492B2 Image guided intracardiac catheters 有权
标题翻译：图像引导的心内导管
公开(公告)号：US08414492B2
公开(公告)日：2013-04-09
申请号：US12509880
申请日：2009-07-27
申请人： Andreas Hadjicostis
发明人： Andreas Hadjicostis
IPC分类号： A61B8/00
CPC分类号： A61B8/4488 , A61B5/042 , A61B8/12 , A61B8/4272 , A61B8/445 , A61B18/1492 , A61B2017/003 , A61B2018/0016 , A61B2018/00166 , A61B2018/00351 , A61B2018/00357 , A61B2018/00791 , A61B2018/00839 , A61B2018/1497 , A61B2090/3782 , A61B2090/3784 , A61N2007/0078
摘要： An intracardiac catheter for ultrasound guided ablation and EP mapping. Ablation and mapping electrodes 34, 36, 38, 39 are carried on the surface of an outer catheter 30 and an ultrasound array is mounted inside an inner catheter 20. Backloading the inner catheter into the outer catheter provides the ultrasound array in position to image tissue near the surface electrodes. An acoustic coupling fluid is provided between the catheters and a number of the electrodes 34, 38 are positioned directly within the image field of the array.
摘要翻译：用于超声引导消融和EP映射的心内导管。消融和测绘电极34,36,38,39承载在外导管30的表面上，并且超声阵列安装在内导管20的内部。将内导管重新加载到外导管中将超声阵列置于图像组织的位置靠近表面电极。在导管之间提供声耦合流体，并且多个电极34,38直接位于阵列的图像场内。

4. 发明申请

US20190150893A1 Image Guided Intravascular Therapy Catheter Utilizing a Thin Chip Multiplexor 审中-公开
公开(公告)号：US20190150893A1
公开(公告)日：2019-05-23
申请号：US16259740
申请日：2019-01-28
申请人： Andreas Hadjicostis
发明人： Andreas Hadjicostis
IPC分类号： A61B8/00 , A61B8/12 , A61B18/14
摘要： A medical device that includes an array of ultrasound elements and an integrated circuit, proximal to the ultrasound elements, having a thickness of less than 40 μm, and having an array of ultrasound element driving-and-receiving contacts, matching the array of ultrasound elements and collectively electrically connected to each of the ultrasound elements. The integrated circuit also having a set of input-output signal contacts, the set being collectively switchable into contact with any one of a set of predefined blocks of driving-and-receiving contacts, and a set of control contacts, wherein inputs received by the control contacts collectively command some aspect of chip operation. The medical device further includes a set a protective covering.

5. 发明申请

US20090292209A1 INTRACARDIAC CATHETERS WITH IMAGE FIELD ELECTRODES 有权
标题翻译：具有图像场电极的入射导管
公开(公告)号：US20090292209A1
公开(公告)日：2009-11-26
申请号：US12509902
申请日：2009-07-27
申请人： Andreas Hadjicostis
发明人： Andreas Hadjicostis
IPC分类号： A61B8/14
CPC分类号： A61B8/4488 , A61B5/042 , A61B8/12 , A61B8/4272 , A61B8/445 , A61B18/1492 , A61B2017/003 , A61B2018/0016 , A61B2018/00166 , A61B2018/00351 , A61B2018/00357 , A61B2018/00791 , A61B2018/00839 , A61B2018/1497 , A61B2090/3782 , A61B2090/3784 , A61N2007/0078
摘要： An intracardiac catheter for ultrasound guided ablation and EP mapping. Ablation and mapping electrodes 34, 36, 38, 39 are carried on the surface of an outer catheter 30 and an ultrasound array is mounted inside an inner catheter 20. Backloading the inner catheter into the outer catheter provides the ultrasound array in position to image tissue near the surface electrodes. An acoustic coupling fluid is provided between the catheters and a number of the electrodes 34, 38 are positioned directly within the image field of the array.
摘要翻译：用于超声引导消融和EP映射的心内导管。消融和测绘电极34,36,38,39承载在外导管30的表面上，并且超声阵列安装在内导管20的内部。将内导管重新加载到外导管中将超声阵列置于图像组织的位置靠近表面电极。在导管之间提供声耦合流体，并且多个电极34,38直接位于阵列的图像场内。

6. 发明申请

US20090287090A1 IMAGE GUIDED INTRACARDIAC CATHETERS 有权
标题翻译：图像指导内镜导管
公开(公告)号：US20090287090A1
公开(公告)日：2009-11-19
申请号：US12509880
申请日：2009-07-27
申请人： Andreas Hadjicostis
发明人： Andreas Hadjicostis
IPC分类号： A61B18/14 , A61B8/14
CPC分类号： A61B8/4488 , A61B5/042 , A61B8/12 , A61B8/4272 , A61B8/445 , A61B18/1492 , A61B2017/003 , A61B2018/0016 , A61B2018/00166 , A61B2018/00351 , A61B2018/00357 , A61B2018/00791 , A61B2018/00839 , A61B2018/1497 , A61B2090/3782 , A61B2090/3784 , A61N2007/0078
摘要： An intracardiac catheter for ultrasound guided ablation and EP mapping. Ablation and mapping electrodes 34, 36, 38, 39 are carried on the surface of an outer catheter 30 and an ultrasound array is mounted inside an inner catheter 20. Backloading the inner catheter into the outer catheter provides the ultrasound array in position to image tissue near the surface electrodes. An acoustic coupling fluid is provided between the catheters and a number of the electrodes 34, 38 are positioned directly within the image field of the array.
摘要翻译：用于超声引导消融和EP映射的心内导管。消融和测绘电极34,36,38,39承载在外导管30的表面上，并且超声阵列安装在内导管20的内部。将内导管重新加载到外导管中将超声阵列置于图像组织的位置靠近表面电极。在导管之间提供声耦合流体，并且多个电极34,38直接位于阵列的图像场内。

7. 发明授权

US07195179B2 Piezoelectric mist generation device 失效
标题翻译：压电雾生成装置
公开(公告)号：US07195179B2
公开(公告)日：2007-03-27
申请号：US10858489
申请日：2004-06-01
申请人： Craig Miller , Andreas Hadjicostis
发明人： Craig Miller , Andreas Hadjicostis
IPC分类号： A62C13/62 , B05B1/08 , B05B1/26 , B05B17/04 , A61M11/06
CPC分类号： B05B17/0669 , B05B17/0615
摘要： An apparatus of the present invention includes: a container operable to hold a liquid; circuitry operable to provide an electrical stimulus; and a piezoelectric element electrically coupled to the circuitry. The piezoelectric element includes a first face positioned beneath the liquid when the liquid is placed in the container, the piezoelectric element being responsive to the electrical stimulus to produce acoustic energy that causes droplets to form from the liquid. The piezoelectric element has a focal length along a focal axis intersecting the first face. The piezoelectric element and the container are structured in relation to one another to form an oblique angle between the focal axis and an axis generally parallel to a surface of the liquid when the liquid is at rest in the container.
摘要翻译：本发明的装置包括：可操作以容纳液体的容器; 用于提供电刺激的电路; 以及电耦合到所述电路的压电元件。压电元件包括当液体被放置在容器中时位于液体下方的第一面，压电元件响应于电刺激产生导致从液体形成液滴的声能。压电元件具有沿着与第一面交叉的焦轴的焦距。当液体在容器中静止时，压电元件和容器相互关联地构成，以在焦点轴线和大致平行于液体表面的轴线之间形成倾斜角度。

8. 发明授权

US10492760B2 Image guided intravascular therapy catheter utilizing a thin chip multiplexor 有权
公开(公告)号：US10492760B2
公开(公告)日：2019-12-03
申请号：US16259740
申请日：2019-01-28
申请人： Andreas Hadjicostis
发明人： Andreas Hadjicostis
IPC分类号： A61B8/00 , A61B8/12 , A61B18/14 , A61B18/00 , A61B90/00
CPC分类号： A61B8/445 , A61B8/12 , A61B18/1492 , A61B8/4488 , A61B8/56 , A61B2018/00351 , A61B2018/00386 , A61B2018/00577 , A61B2018/00982 , A61B2090/3784
摘要： A medical device that includes an array of ultrasound elements and an integrated circuit, proximal to the ultrasound elements, having a thickness of less than 40 μm, and having an array of ultrasound element driving-and-receiving contacts, matching the array of ultrasound elements and collectively electrically connected to each of the ultrasound elements. The integrated circuit also having a set of input-output signal contacts, the set being collectively switchable into contact with any one of a set of predefined blocks of driving-and-receiving contacts, and a set of control contacts, wherein inputs received by the control contacts collectively command some aspect of chip operation. The medical device further includes a set a protective covering.

9. 发明授权

US08702609B2 Image-guided intravascular therapy catheters 有权
标题翻译：图像导向血管内治疗导管
公开(公告)号：US08702609B2
公开(公告)日：2014-04-22
申请号：US12122456
申请日：2008-05-16
申请人： Andreas Hadjicostis
发明人： Andreas Hadjicostis
IPC分类号： A61B8/00
CPC分类号： A61B18/1492 , A61B8/12 , A61B8/445 , A61B8/4483 , A61B8/4488 , A61B8/483 , A61B2018/00422 , A61B2018/1467 , A61B2090/3782
摘要： An intravascular ultrasound catheter having an imaging array and ablation electrodes is provided. The imaging array and ablation electrodes are forward facing and the catheter can be used to ablate plaque in partially or totally occluded blood vessels under real time ultrasound visualization. The ablation electrodes are integrated into the distal face of the catheter and allow ultrasound to pass through them, which provides the ability to achieve highly accurate real time visualization of the tissue undergoing treatment.
摘要翻译：提供具有成像阵列和消融电极的血管内超声导管。成像阵列和消融电极是面向前的，并且导管可用于在实时超声可视化下在部分或完全闭塞的血管中消融斑块。消融电极整合到导管的远端，并允许超声波通过它们，这提供了实现经过治疗的组织的高精度实时可视化的能力。

10. 发明授权

US08425421B2 Intracardiac catheters with image field electrodes 有权
标题翻译：具有图像场电极的心内导管
公开(公告)号：US08425421B2
公开(公告)日：2013-04-23
申请号：US12509902
申请日：2009-07-27
申请人： Andreas Hadjicostis
发明人： Andreas Hadjicostis
IPC分类号： A61B8/00
CPC分类号： A61B8/4488 , A61B5/042 , A61B8/12 , A61B8/4272 , A61B8/445 , A61B18/1492 , A61B2017/003 , A61B2018/0016 , A61B2018/00166 , A61B2018/00351 , A61B2018/00357 , A61B2018/00791 , A61B2018/00839 , A61B2018/1497 , A61B2090/3782 , A61B2090/3784 , A61N2007/0078
摘要： An intracardiac catheter for ultrasound guided ablation and EP mapping. Ablation and mapping electrodes 34, 36, 38, 39 are carried on the surface of an outer catheter 30 and an ultrasound array is mounted inside an inner catheter 20. Backloading the inner catheter into the outer catheter provides the ultrasound array in position to image tissue near the surface electrodes. An acoustic coupling fluid is provided between the catheters and a number of the electrodes 34, 38 are positioned directly within the image field of the array.
摘要翻译：用于超声引导消融和EP映射的心内导管。消融和测绘电极34,36,38,39承载在外导管30的表面上，并且超声阵列安装在内导管20的内部。将内导管重新加载到外导管中将超声阵列置于图像组织的位置靠近表面电极。在导管之间提供声耦合流体，并且多个电极34,38直接位于阵列的图像场内。

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